naltrexone and Inflammation

naltrexone has been researched along with Inflammation in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (21.82)	18.2507
2000's	20 (36.36)	29.6817
2010's	13 (23.64)	24.3611
2020's	10 (18.18)	2.80

Authors

Authors	Studies
Lie, MRKL; Paulides, E; van der Woude, CJ	1
Abdel-Mohsen, M; Azzoni, L; Fair, M; Giron, LB; Hiserodt, E; Lalley-Chareczko, L; Lynn, K; Montaner, LJ; Mounzer, K; Trooskin, S; Vadrevu, S; Zhao, L	1
Glover, SC; Hoeh, NR; Lin, JC; Moloney, BD; Muthukumaraswamy, S; Plank, JR; Sumner, RL; Sundram, F	1
Di Cerbo, A; Iannitti, T; Morales-Medina, JC; Pugliese, N; Zizzadoro, C	1
Chadwick, AL; Rupp, A; Young, E	1
Jiao, T; Shan, F; Wang, Y; Xu, N; Xue, H; Zhang, N; Zhao, S	1
Shabeeb, N	1
Barrientos, RM; Clements, MA; Duran-Malle, JC; Harris, KM; Kwilasz, AJ; Larson, TA; Litwiler, ST; Maier, SF; Mitten, EH; Rice, KC; Schrama, AEW; Todd, LS; Van Dam, AM; Wang, X; Watkins, LR	1
Choubey, A; Ghosh, D; Girdhar, K; Kar, AK; Kushwaha, S; Mondal, P; Yadav, MK	1
Ballet, S; Bermudez, M; De Neve, J; Dumitrascuta, M; Spetea, M; Trovato, O; Wolber, G	1
Berlau, DJ; Patten, DK; Schultz, BG	1
de Lima, A; Fuhler, GM; Lie, MRKL; Peppelenbosch, MP; van der Ent, C; van der Giessen, J; van der Woude, CJ	1
Hackel, D; Peng, F; Rittner, HL; Wang, Y	1
Immonen, JA; McLaughlin, PJ; Zagon, IS	1
Herrero, JF; Herrero-Zorita, C; Ramos-Zepeda, GA	1
Beaudry, H; Gendron, L; Morón, JA	1
Brederson, JD; Honda, CN	1
Beck, P; Bonacorso, HG; Drewes, C; Ferreira, J; Machado, P; Martins, MA; Mello, CF; Milano, J; Oliveira, SM; Rossato, MF; Rubin, MA; Zanatta, N	1
Brown, N; Panksepp, J	1
Dunlop, SA; Farid, WO; Hulse, GK; McCallum, D; Tait, RJ	1
Bakhle, YS; de Francischi, JN; Dos Reis, WG; Duarte, ID; Lima, PP; Rezende, RM	1
Delaney, CP; Stulberg, JJ; Zeinali, F	1
Fuchs, PN; Uhelski, ML	1
Hervera, A; Leánez, S; Negrete, R; Pol, O	1
Bakhle, YS; de Francischi, JN; dos Reis, WG; Ferreira-Alves, DL; Gassani, BC; Paiva-Lima, P; Rezende, RM	1
Lawson, KP; Mokha, SS; Nag, S; Thompson, AD	1
Chicre-Alcântara, TC; Clemente-Napimoga, JT; Fischer, L; Melo, V; Parada, CA; Tambeli, CH; Torres-Chávez, KE	1
Berman, BM; Lao, L; Li, A; Meng, X; Ren, K; Tan, M; Xin, J; Zhang, RX; Zhang, Y	1
Chateauraynaud, J; Gavello-Baudy, S; Laboureyras, E; Laulin, JP; Le Roy, C; Simonnet, G	1
Bakhle, YS; Camêlo, VM; Dos Reis, WG; Faraco, A; Francischi, JN; Paiva-Lima, P; Rezende, RM	1
Dimitrijević, M; Kovacević-Jovanović, V; Radulović, J; Stanojević, S; Vujić, V	1
Lundeberg, T; Yu, LC; Yu, SQ	1
Ise, Y; Kishimoto, Y; Misawa, K; Narita, M; Suzuki, T; Yajima, Y	1
Dimitrijević, M; Kovacević-Jovanović, V; Mitić, K; Stanojević, S; Vujić, V	1
Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Kim, SK; Lee, MK; Lim, KH; Yang, GY; Yoon, YW	1
Ackermann, LW; Denning, GM; Dickson, EW; Hogrefe, CP; Ludwig, PS; Stoll, LL	1
Chavkin, C; Gendron, L; Pintar, JE	1
Bakhle, YS; dos Reis, WG; França, DS; Francischi, JN; Menezes, GB; Rezende, RM	1
Grau, JW; Hook, MA; Huie, JR	1
Asehnoune, K; Beloeil, H; Benhamou, D; Bonnet, MP; Mazoit, JX	1
Imai, Y; Schäfer, M; Stein, C; Uhl, GR	1
Kovelowski, CJ; Ossipov, MH; Porreca, F	1
Dickenson, AH; Stanfa, LC	1
Grubb, BD; Schaible, HG; Stiller, RU	1
Bianchi, M; Panerai, AE; Sacerdote, P	1
Aarnisalo, AA; Idänpään-Heikkilä, JJ; Kalso, E; Kontinen, VK; Panula, P	1
Kishimoto, Y; Misawa, M; Nagase, H; Suzuki, T; Takeda, F	1
Besson, JM; Catheline, G; Le Guen, S	2
Hammond, DL; Hurley, RW	1
Benowitz, NL; Levine, JD; Miao, FJ	1
Binder, W; Junien, JL; Machelska, H; Mousa, S; Rivière, PJ; Schäfer, M; Schmitt, T; Stein, C	1
Gold, MS; Liebeskind, JC; Morgan, MM; Stein, C	1
Członkowski, A; Herz, A; Parsons, CG; Stein, C	1
Herz, A; Parsons, CG	1

Reviews

3 review(s) available for naltrexone and Inflammation

Article	Year
Low-dose naltrexone's utility for non-cancer centralized pain conditions: a scoping review. Pain medicine (Malden, Mass.), 2023, Nov-02, Volume: 24, Issue:11 Topics: Chronic Disease; Chronic Pain; Humans; Inflammation; Naltrexone; Quality of Life	2023
The Safety and Efficacy of Low-Dose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohn's Disease, and Other Chronic Pain Disorders. Pharmacotherapy, 2018, Volume: 38, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Chronic Pain; Crohn Disease; Dose-Response Relationship, Drug; Fibromyalgia; Humans; Inflammation; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Quality of Life	2018
Pharmacological management of postoperative ileus. Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bisacodyl; Cathartics; Cisapride; Dihydroergotamine; Humans; Ileus; Inflammation; Naltrexone; Neostigmine; Parasympathomimetics; Piperidines; Postoperative Complications; Propranolol; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Serotonin Receptor Agonists	2009

Trials

3 trial(s) available for naltrexone and Inflammation

Article	Year
Low-dose naltrexone for the induction of remission in patients with mild to moderate Crohn's disease: protocol for the randomised, double-blinded, placebo-controlled, multicentre LDN Crohn study. BMJ open, 2022, 04-08, Volume: 12, Issue:4 Topics: Crohn Disease; Humans; Inflammation; Inflammatory Bowel Diseases; Multicenter Studies as Topic; Naltrexone; Randomized Controlled Trials as Topic; Remission Induction	2022
A randomized, double-blind, placebo-controlled, hybrid parallel-arm study of low-dose naltrexone as an adjunctive anti-inflammatory treatment for major depressive disorder. Trials, 2022, Sep-30, Volume: 23, Issue:1 Topics: Anti-Inflammatory Agents; Australia; Biomarkers; C-Reactive Protein; Depressive Disorder, Major; Double-Blind Method; Humans; Inflammation; Naltrexone; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome	2022
Low dose Naltrexone for induction of remission in inflammatory bowel disease patients. Journal of translational medicine, 2018, 03-09, Volume: 16, Issue:1 Topics: Adult; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoscopy; Epithelial Cells; Female; Humans; Inflammation; Inflammatory Bowel Diseases; Interleukin-8; Intestinal Mucosa; Male; Middle Aged; Naltrexone; Remission Induction; Wound Healing	2018

Other Studies

49 other study(ies) available for naltrexone and Inflammation

Article	Year
Methadone use is associated with increased levels of sCD14, immune activation, and inflammation during suppressed HIV infection. Journal of leukocyte biology, 2022, Volume: 112, Issue:4 Topics: Analgesics, Opioid; Cross-Sectional Studies; Cytokines; HIV Infections; Humans; Immunoglobulin G; Inflammation; Lipopolysaccharide Receptors; Methadone; Naltrexone; Pilot Projects; Receptors, Opioid, mu	2022
Evidence for Endogenous Opioid Dependence Related to Latent Sensitization in a Rat Model of Chronic Inflammatory Pain. International journal of molecular sciences, 2023, Feb-01, Volume: 24, Issue:3 Topics: Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Drug Inverse Agonism; Hyperalgesia; Inflammation; Mice; Naltrexone; Opioid Peptides; Opioid-Related Disorders; Rats; Rats, Wistar	2023
Naltrexone (NTX) relieves inflammation in the collagen-induced- arthritis (CIA) rat models through regulating TLR4/NFκB signaling pathway. International immunopharmacology, 2020, Volume: 79 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Humans; Inflammation; Naltrexone; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; T-Lymphocyte Subsets; Th17 Cells; Toll-Like Receptor 4	2020
The lowdown on low-dose naltrexone. Cutis, 2020, Volume: 105, Issue:1 Topics: Dose-Response Relationship, Drug; Humans; Inflammation; Naltrexone; Narcotic Antagonists; Off-Label Use; Skin Diseases	2020
Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone. Behavioural brain research, 2021, 01-01, Volume: 396 Topics: Animals; Behavior, Animal; Cells, Cultured; Conditioning, Classical; Encephalomyelitis, Autoimmune, Experimental; Fear; Hippocampus; Inflammation; Male; Memory Disorders; Mice; Microglia; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4	2021
Low-dose naltrexone rescues inflammation and insulin resistance associated with hyperinsulinemia. The Journal of biological chemistry, 2020, 11-27, Volume: 295, Issue:48 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hyperinsulinism; Inflammation; Insulin Resistance; Male; Mice; Naltrexone; RAW 264.7 Cells; Sirtuin 1; Transcription Factor RelA	2020
Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking. Molecules (Basel, Switzerland), 2021, 05-28, Volume: 26, Issue:11 Topics: Acute Pain; Analgesics; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Cycloheptanes; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Mice; Models, Molecular; Molecular Docking Simulation; Morphine; Movement; Naloxone; Naltrexone; Nociceptin; Oligopeptides; Opioid Peptides; Pain Management; Piperidines; Receptors, Opioid, mu	2021
Long-term antinociception by electroacupuncture is mediated via peripheral opioid receptors in free-moving rats with inflammatory hyperalgesia. European journal of pain (London, England), 2013, Volume: 17, Issue:10 Topics: Acupuncture Analgesia; Acupuncture Points; Animals; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Naloxone; Naltrexone; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid; Time	2013
Topical naltrexone accelerates full-thickness wound closure in type 1 diabetic rats by stimulating angiogenesis. Experimental biology and medicine (Maywood, N.J.), 2013, Volume: 238, Issue:7 Topics: Actins; Administration, Topical; Animals; Blood Glucose; Body Weight; Cell Count; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fibroblast Growth Factor 2; Hyperglycemia; Inflammation; Male; Mast Cells; Naltrexone; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Skin; Streptozocin; Vascular Endothelial Growth Factor A; Wound Healing	2013
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes. Behavioural pharmacology, 2014, Volume: 25, Issue:8 Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord	2014
Implication of delta opioid receptor subtype 2 but not delta opioid receptor subtype 1 in the development of morphine analgesic tolerance in a rat model of chronic inflammatory pain. The European journal of neuroscience, 2015, Volume: 41, Issue:7 Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Freund's Adjuvant; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats, Sprague-Dawley; Receptors, Opioid, delta	2015
Primary afferent neurons express functional delta opioid receptors in inflamed skin. Brain research, 2015, Jul-21, Volume: 1614 Topics: Action Potentials; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Freund's Adjuvant; Inflammation; Male; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Oligopeptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Skin	2015
Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice. Life sciences, 2008, Nov-21, Volume: 83, Issue:21-22 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dipyrone; Freund's Adjuvant; Indomethacin; Inflammation; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain, Postoperative; Postural Balance; Pyrazoles; Stomach Ulcer	2008
Low-dose naltrexone for disease prevention and quality of life. Medical hypotheses, 2009, Volume: 72, Issue:3 Topics: Cytokines; Dose-Response Relationship, Drug; Humans; Inflammation; Models, Immunological; Naltrexone; Narcotic Antagonists; Neoplasms; Quality of Life	2009
Minor pathological changes are induced by naltrexone-poly(DL-lactide) implants in pregnant rats. Journal of biomedical materials research. Part A, 2009, Dec-15, Volume: 91, Issue:4 Topics: Animals; Biocompatible Materials; Birefringence; Female; Foreign-Body Reaction; Implants, Experimental; Inflammation; Male; Naltrexone; Polyesters; Pregnancy; Rats; Rats, Sprague-Dawley; Skin	2009
The analgesic actions of centrally administered celecoxib are mediated by endogenous opioids. Pain, 2009, Volume: 142, Issue:1-2 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Immunologic Factors; Inflammation; Injections, Intraventricular; Leucine; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Reaction Time; Sulfonamides; Time Factors	2009
Naltrexone fails to increase pain affect in response to inflammatory pain in a novel escape/avoidance paradigm. Physiology & behavior, 2009, Sep-07, Volume: 98, Issue:3 Topics: Animals; Avoidance Learning; Carrageenan; Dose-Response Relationship, Drug; Drug Interactions; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley	2009
The peripheral administration of a nitric oxide donor potentiates the local antinociceptive effects of a DOR agonist during chronic inflammatory pain in mice. Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 380, Issue:4 Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Enkephalin, D-Penicillamine (2,5)-; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Pain Measurement; Receptors, Opioid, delta; Time Factors	2009
Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity? Pharmacological research, 2010, Volume: 62, Issue:5 Topics: Acetazolamide; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Hyperalgesia; Inflammation; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides	2010
Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia. Pain, 2010, Volume: 151, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Area Under Curve; Dose-Response Relationship, Drug; Estradiol; Estrous Cycle; Female; Inflammation; Injections, Spinal; Lumbosacral Region; Male; Naltrexone; Orchiectomy; Ovariectomy; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics; Spinal Cord; Testosterone	2010
Local kappa opioid receptor activation decreases temporomandibular joint inflammation. Inflammation, 2012, Volume: 35, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Dose-Response Relationship, Drug; Formaldehyde; Inflammation; Male; Naltrexone; Neutrophil Infiltration; Neutrophils; Rats; Rats, Wistar; Receptors, Opioid, kappa; Temporomandibular Joint	2012
Acupuncture alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia. Neurochemical research, 2011, Volume: 36, Issue:11 Topics: Affect; Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Gyrus Cinguli; Hyperalgesia; Inflammation; Male; Naltrexone; Pain Management; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin	2011
Endogenous opioids released during non-nociceptive environmental stress induce latent pain sensitization Via a NMDA-dependent process. The journal of pain, 2011, Volume: 12, Issue:10 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Carrageenan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fentanyl; Hyperalgesia; Inflammation; Ketamine; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming; Time Factors	2011
Endogenous opioid and cannabinoid mechanisms are involved in the analgesic effects of celecoxib in the central nervous system. Pharmacology, 2012, Volume: 89, Issue:3-4 Topics: Analgesics; Animals; Carrageenan; Celecoxib; Central Nervous System; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Inflammation; Male; Naltrexone; Pain; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfonamides	2012
Different effects of methionine-enkephalin on paw edema in two inbred rat strains. Peptides, 2002, Volume: 23, Issue:9 Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Edema; Enkephalin, Methionine; Glucocorticoids; Inflammation; Kinetics; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Species Specificity; Time Factors	2002
Involvement of oxytocin in spinal antinociception in rats with inflammation. Brain research, 2003, Sep-05, Volume: 983, Issue:1-2 Topics: Analgesics; Animals; Carrageenan; Hot Temperature; Inflammation; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxytocin; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Vasotocin	2003
Direct evidence for the involvement of the mesolimbic kappa-opioid system in the morphine-induced rewarding effect under an inflammatory pain-like state. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:1 Topics: Animals; Brain Chemistry; Conditioning, Operant; Dopamine; Dynorphins; Edema; Foot; Formaldehyde; Inflammation; Limbic System; Male; Microdialysis; Microinjections; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward	2005
Beta-endorphin differentially affects inflammation in two inbred rat strains. European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3 Topics: Animals; beta-Endorphin; Concanavalin A; Dose-Response Relationship, Drug; Edema; Female; Granulocytes; Hindlimb; Inflammation; Male; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nitric Oxide; Phagocytosis; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, kappa; Species Specificity	2006
Intramuscular administration of morphine reduces mustard-oil-induced craniofacial-muscle pain behavior in lightly anesthetized rats. European journal of pain (London, England), 2008, Volume: 12, Issue:3 Topics: Analgesics; Anesthesia, General; Animals; Inflammation; Injections; Injections, Intramuscular; Male; Masseter Muscle; Morphine; Mustard Plant; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Plant Oils; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Single-Blind Method; Somatostatin	2008
Exercise enhances myocardial ischemic tolerance via an opioid receptor-dependent mechanism. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1 Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression; Inflammation; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Narcotic Antagonists; Opioid Peptides; Physical Exertion; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid; RNA, Messenger; Time Factors	2008
Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia. Neuroscience, 2007, Dec-19, Volume: 150, Issue:4 Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Protein Precursors; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin	2007
Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain. British journal of pharmacology, 2008, Volume: 153, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carrageenan; Dipyrone; Disease Models, Animal; Hyperalgesia; Inflammation; Injections, Intralesional; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Rats, Wistar; Research Design; Time Factors	2008
Peripheral inflammation undermines the plasticity of the isolated spinal cord. Behavioral neuroscience, 2008, Volume: 122, Issue:1 Topics: Analysis of Variance; Animals; Capsaicin; Conditioning, Psychological; Dose-Response Relationship, Drug; Electric Stimulation; Inflammation; Learning Disabilities; Male; Naltrexone; Narcotic Antagonists; Neuronal Plasticity; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord Injuries; Time Factors; Touch	2008
The mu opioid receptor mediates morphine-induced tumor necrosis factor and interleukin-6 inhibition in toll-like receptor 2-stimulated monocytes. Anesthesia and analgesia, 2008, Volume: 106, Issue:4 Topics: Cell Separation; Cells, Cultured; Cytokines; Humans; Inflammation; Interleukin-6; Monocytes; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha	2008
Inflammation enhances peripheral mu-opioid receptor-mediated analgesia, but not mu-opioid receptor transcription in dorsal root ganglia. European journal of pharmacology, 1995, Jun-12, Volume: 279, Issue:2-3 Topics: Amino Acid Sequence; Analgesia; Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Foot; Ganglia, Spinal; Inflammation; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, mu; Ribonucleases; RNA, Messenger	1995
The increase in morphine antinociceptive potency produced by carrageenan-induced hindpaw inflammation is blocked by naltrindole, a selective delta-opioid antagonist. Neuroscience letters, 1995, Jan-30, Volume: 184, Issue:3 Topics: Animals; Carrageenan; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1995
Electrophysiological studies on the spinal roles of endogenous opioids in carrageenan inflammation. Pain, 1994, Volume: 56, Issue:2 Topics: Analgesics; Animals; Carrageenan; Dipeptides; Dynorphins; Electrophysiology; Endorphins; Inflammation; Injections, Spinal; Male; Microelectrodes; Naltrexone; Nerve Fibers; Neurons; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission	1994
Neurophysiological evidence for increased kappa opioidergic control of spinal cord neurons in rats with unilateral inflammation at the ankle. The European journal of neuroscience, 1993, Nov-01, Volume: 5, Issue:11 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Arthritis, Experimental; Freund's Adjuvant; Inflammation; Joints; Male; Naltrexone; Neurons; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reference Values; Spinal Cord; Stress, Mechanical	1993
Involvement of beta-endorphin in the modulation of paw inflammatory edema in the rat. Regulatory peptides, 1996, Jul-05, Volume: 63, Issue:2-3 Topics: Animals; Antibodies; Benzomorphans; beta-Endorphin; Edema; Enkephalin, Leucine; Foot; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Yeasts	1996
Neuropeptide FF in the rat spinal cord during carrageenan inflammation. Peptides, 1997, Volume: 18, Issue:2 Topics: Animals; Carrageenan; Hot Temperature; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Neurons; Neuropeptides; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord	1997
Role of the kappa-opioid system in the attenuation of the morphine-induced place preference under chronic pain. Life sciences, 1999, Volume: 64, Issue:1 Topics: Animals; Chronic Disease; Conditioning, Psychological; Formaldehyde; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Reward; Time Factors	1999
Effects of opioid receptor antagonists on the effects of i.v. morphine on carrageenin evoked c-Fos expression in the superficial dorsal horn of the rat spinal cord. Brain research, 1999, Apr-03, Volume: 824, Issue:1 Topics: Analgesics, Opioid; Animals; Carrageenan; Hindlimb; Inflammation; Injections, Intravenous; Male; Morphine; Naltrexone; Narcotic Antagonists; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord	1999
Effects of U-69,593, a kappa-opioid receptor agonist, on carrageenin-induced peripheral oedema and Fos expression in the rat spinal cord. European journal of pharmacology, 1999, Apr-16, Volume: 370, Issue:3 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzeneacetamides; Carrageenan; Dose-Response Relationship, Drug; Drug Interactions; Edema; Immunochemistry; Inflammation; Male; Naltrexone; Narcotic Antagonists; Photomicrography; Proto-Oncogene Proteins c-fos; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spinal Cord	1999
Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-01, Volume: 21, Issue:7 Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Inflammation; Male; Microinjections; Naltrexone; Pain; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	2001
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. British journal of pharmacology, 2001, Volume: 133, Issue:1 Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors	2001
Analgesic and antiinflammatory effects of two novel kappa-opioid peptides. Anesthesiology, 2001, Volume: 94, Issue:6 Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Dose-Response Relationship, Drug; Inflammation; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Threshold; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa	2001
Periaqueductal gray stimulation produces a spinally mediated, opioid antinociception for the inflamed hindpaw of the rat. Brain research, 1991, Apr-05, Volume: 545, Issue:1-2 Topics: Analysis of Variance; Animals; Electric Stimulation; Freund's Adjuvant; Hindlimb; Inflammation; Male; Mycobacterium; Naloxone; Naltrexone; Pain; Periaqueductal Gray; Rats; Rats, Inbred Strains; Spinal Cord	1991
Peripheral opioid receptors mediating antinociception in inflammation. Activation by endogenous opioids and role of the pituitary-adrenal axis. Pain, 1990, Volume: 41, Issue:1 Topics: Adrenalectomy; Analysis of Variance; Animals; Cold Temperature; Dose-Response Relationship, Drug; Endorphins; Foot; Hypophysectomy; Inflammation; Male; Naloxone; Naltrexone; Nociceptors; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming	1990
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2 Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan	1990