naltrexone and Disease Models, Animal

Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Brain; Buprenorphine; Disease Models, Animal; Endocannabinoids; Glutamic Acid; Humans; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Orexins; Reward; Secondary Prevention; Signal Transduction; Treatment Outcome

Topics: Animals; Disease Models, Animal; Humans; Naltrexone; Narcotic Antagonists; Neoplasms; Receptors, Opioid

Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish

Topics: Aldehyde Reductase; Animals; Corneal Diseases; Diabetes Complications; Disease Models, Animal; Enzyme Inhibitors; Humans; Insulin; Naltrexone; Wound Healing

Topics: Alcohol Deterrents; Alcoholism; Animals; Clinical Trials as Topic; Disease Models, Animal; Humans; Mice; Mutation, Missense; Naltrexone; Polymorphism, Single Nucleotide; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Animals; Corneal Diseases; Diabetes Complications; Disease Models, Animal; Epithelium; Humans; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Wound Healing

Topics: Alcoholism; Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Excitatory Amino Acids; Genetic Predisposition to Disease; Humans; Mice; Naltrexone; Narcotic Antagonists; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid, mu; Social Environment; Stress, Psychological

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Naltrexone; Rodentia; Taurine

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Baclofen; Corticotropin-Releasing Hormone; Disease Models, Animal; Disulfiram; Fructose; Humans; Naltrexone; Neuropeptide Y; Nociceptin; Ondansetron; Opioid Peptides; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Taurine; Topiramate

Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome

Topics: Alcoholism; Animals; Choice Behavior; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ibogaine; Naltrexone; Narcotics; Phytotherapy; Piperazines; Point Mutation; Pueraria; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Serotonin Antagonists

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Carbamazepine; Depression; Disease Models, Animal; Disulfiram; Fructose; Humans; Naltrexone; Secondary Prevention; Taurine; Topiramate

Topics: Acamprosate; Alcoholism; Animals; Behavior, Animal; Calcium Channels; Disease Models, Animal; Humans; Naltrexone; Narcotic Antagonists; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Recurrence; Substance Withdrawal Syndrome; Synaptic Transmission; Taurine

Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Drug Tolerance; Motivation; Naltrexone; Narcotic Antagonists; Predictive Value of Tests; Rats; Reinforcement, Psychology; Reproducibility of Results; Substance Withdrawal Syndrome; Taurine

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Clinical Trials as Topic; Disease Models, Animal; Dopamine Agents; Humans; Naltrexone; Narcotic Antagonists; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate; Secondary Prevention; Serotonin Agents; Taurine

Topics: Animals; Cholestasis; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Guanidines; Ligation; Male; Maze Learning; Memory Disorders; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Space Perception; Time Factors

Topics: Adult; Animal Feed; Animals; Antidepressive Agents; Bupropion; Disease Models, Animal; Drug Therapy, Combination; Fasting; Female; Humans; Male; Mice; Mice, Obese; Naltrexone; Narcotic Antagonists; Obesity; Overweight; United States; Weight Loss

Topics: Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chemokine CCL5; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Morphine; Naloxone; Pain; Pain Measurement; Receptors, CCR5

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Analgesics, Opioid; Animals; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Male; Morphine; Naltrexone; Neuroinflammatory Diseases; Neuroprotective Agents; Rats; Rats, Wistar

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Female; Hindlimb; Humans; Naltrexone; Narcotic Antagonists; Pilot Projects; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries

Topics: Animals; Antipruritics; Behavior, Animal; Chloroquine; Deoxycholic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Nalbuphine; Naltrexone; Narcotic Antagonists; Pruritus; Receptors, Opioid, kappa; tat Gene Products, Human Immunodeficiency Virus

Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Chronic Pain; Disease Models, Animal; Hyperalgesia; Male; Naltrexone; Nociception; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Trigeminal Neuralgia

Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Chitosan; Disease Models, Animal; Immunity, Humoral; Interleukin-17; Interleukin-4; Mice; Mice, Inbred BALB C; Naltrexone; Nanoparticles; Protozoan Proteins; Protozoan Vaccines; Recombinant Proteins; Th1 Cells; Th17 Cells; Toxoplasma

Topics: Animals; Anticonvulsants; Chloroquine; Disease Models, Animal; Electroshock; Mefloquine; Mice; Naltrexone; Nitrites; Pentylenetetrazole; Seizures

Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; Mice; Models, Theoretical; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pentylenetetrazole; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Receptors, Opioid; Seizures; Stroke; Sumatriptan; Tumor Necrosis Factor-alpha

Topics: Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Drug Inverse Agonism; Hyperalgesia; Inflammation; Mice; Naltrexone; Opioid Peptides; Opioid-Related Disorders; Rats; Rats, Wistar

Topics: Animals; Antidepressive Agents; Behavior, Animal; Buprenorphine; Depression; Disease Models, Animal; Drug Therapy, Combination; Locomotion; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley

Topics: Acute Lung Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Thoracotomy; Toll-Like Receptor 4

Topics: Animals; Behavior Observation Techniques; Behavior, Animal; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Repositioning; Female; Humans; Male; Mice; Mice, Knockout; Naltrexone; Nucleus Accumbens; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Factors

Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroquine; Disease Models, Animal; Fatty Liver; Glycine; Hippurates; Liver; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Naltrexone; Narcotic Antagonists; Opioid Peptides; Phospholipids; Rats; Receptors, Opioid, mu; Signal Transduction

Topics: Animals; Anticonvulsants; Disease Models, Animal; Hippocampus; Male; Mice; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Receptors, Opioid, delta; Seizures; Signal Transduction; Social Isolation; Stress, Psychological

Topics: Analgesics, Non-Narcotic; Animals; Brain-Derived Neurotrophic Factor; Carbamazepine; Disease Models, Animal; Facial Pain; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Spinal Cord; Trigeminal Neuralgia

Topics: Animals; Bucladesine; Cell Cycle; Cells, Cultured; Cysteine Proteases; Disease Models, Animal; Frontotemporal Dementia; Gene Expression Profiling; Gene Expression Regulation; Gene Knockout Techniques; High-Throughput Nucleotide Sequencing; Humans; Lysosomes; Mice; Microglia; Models, Biological; Naltrexone; Progranulins; Sequence Analysis, RNA; Small Molecule Libraries

Topics: Alcoholism; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Female; gamma-Aminobutyric Acid; Male; Medicine, Ayurvedic; Mice; Naltrexone; Plant Extracts; Plant Roots; Rats, Wistar; Withania

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Hyperinsulinism; Inflammation; Insulin Resistance; Male; Mice; Naltrexone; RAW 264.7 Cells; Sirtuin 1; Transcription Factor RelA

Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Central Nervous System Sensitization; Central Nervous System Stimulants; Conditioning, Classical; Disease Models, Animal; Extinction, Psychological; Male; Mental Recall; Methamphetamine; Mice; Motivation; Naltrexone; Narcotic Antagonists

Topics: Alveolar Bone Loss; Animals; Bone Resorption; Cytokines; Disease Models, Animal; Male; Morphinans; Naltrexone; Narcotic Antagonists; Osteoblasts; Osteoclasts; Periodontitis; Rats; Rats, Wistar; Receptors, Opioid

Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Function Tests; Myocytes, Cardiac; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Opioid; Treatment Outcome; Ventricular Dysfunction, Left; Water Intoxication

Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Antidepressive Agents; Disease Models, Animal; Drug Therapy, Combination; Male; Mice; Mice, Inbred C57BL; Motivation; Naltrexone; Self Administration; Serotonin Plasma Membrane Transport Proteins; Sertraline; Stress Disorders, Post-Traumatic; Stress, Psychological; Time Factors

Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Neuralgia; Stavudine

Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Classical; Conditioning, Operant; Disease Models, Animal; Ethanol; Extinction, Psychological; Male; Mice; Minocycline; Naltrexone; Reward; Secondary Prevention

Topics: Aging; Alcohol Drinking; Animals; Central Nervous System Depressants; Choice Behavior; Disease Models, Animal; Ethanol; Exploratory Behavior; Female; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptors, Opioid, kappa; Restraint, Physical; Risk-Taking; Sex Characteristics; Stress, Psychological

Topics: Animals; Behavior, Animal; Compulsive Behavior; Disease Models, Animal; Dopaminergic Neurons; Dorsal Raphe Nucleus; Female; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Morphinans; Naltrexone; Narcotic Antagonists; Prefrontal Cortex; Receptors, Opioid, kappa; Reinforcement, Psychology; Spiro Compounds; Stress, Psychological; Ventral Tegmental Area

Topics: Alcohol Abstinence; Alcohol Drinking; Alcoholism; Animals; Baclofen; Disease Models, Animal; GABA-B Receptor Agonists; Naltrexone; Papio; Reinforcement, Psychology; Self Administration

Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Darkness; Disease Models, Animal; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Naltrexone; Taurine

Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Proliferation; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Interferon-alpha; Male; Naltrexone; Narcotic Antagonists; Neurons; Rats, Wistar; Receptors, Opioid

Topics: Analgesics; Animals; Cinnamates; Dinoprostone; Disease Models, Animal; Male; Mice; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Receptors, Opioid; Serotonin

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; AMP-Activated Protein Kinases; Animals; Antihypertensive Agents; Apoptosis; Autophagy; Blood Pressure; Cell Proliferation; Cells, Cultured; Chloroquine; Disease Models, Animal; Hypertension, Pulmonary; Male; Myocytes, Smooth Muscle; Naltrexone; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Signal Transduction; TOR Serine-Threonine Kinases

Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunologic Factors; Lung; Mice, Inbred BALB C; Naltrexone; Narcotic Antagonists; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus Vaccines; T-Lymphocyte Subsets; Viral Load

Topics: Animals; Blood Glucose; Disease Models, Animal; Epinephrine; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pure Autonomic Failure; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Serine; Tyrosine 3-Monooxygenase

Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Humans; Injections, Intradermal; Male; Mice; Naltrexone; Narcotic Antagonists; Opioid Peptides; Oxadiazoles; Piperazines; Pruritus; Quaternary Ammonium Compounds; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Sumatriptan

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Deoxycholic Acid; Disease Models, Animal; Drug Tolerance; Dysbiosis; Enterococcus faecalis; Female; Gastrointestinal Microbiome; Metabolome; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Phosphatidylethanolamines; Statistics, Nonparametric

Topics: Animals; Brain Ischemia; Cerebral Arteries; Chromones; Cyclic GMP; Disease Models, Animal; Diterpenes, Clerodane; Male; Morpholines; Naltrexone; NG-Nitroarginine Methyl Ester; Phosphatidylinositol 3-Kinases; Pia Mater; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Hydroxybutyrates; Male; Motivation; Naltrexone; Rats; Self Administration

Topics: Analgesics, Opioid; Animals; Cannabinoid Receptor Antagonists; Convulsants; Disease Models, Animal; Electroshock; Male; Mice; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Piperidines; Pyrazoles; Receptors, Cannabinoid; Seizures; Stress, Psychological

Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Disease Models, Animal; Ethanol; Female; Naltrexone; Nicotine; Nicotinic Antagonists; Picolines; Pyridinium Compounds; Rats; Self Administration; Smoking Cessation Agents; Tobacco Use Disorder; Treatment Outcome; Varenicline

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Binge Drinking; Central Amygdaloid Nucleus; Disease Models, Animal; Dynorphins; Genetic Techniques; Male; Mice; Mice, Inbred C57BL; Naltrexone; Receptors, Opioid, kappa

Topics: Animals; Axons; Baclofen; Charcot-Marie-Tooth Disease; Demyelinating Diseases; Disease Models, Animal; Drug Combinations; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Muscle Weakness; Myelin Proteins; Naltrexone; Neural Conduction; Phosphatidylinositol 3-Kinases; Proof of Concept Study; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Schwann Cells; Signal Transduction; Sorbitol

Topics: Animals; Central Amygdaloid Nucleus; Chronic Pain; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Naltrexone; Narcotic Antagonists; Neural Inhibition; Neuralgia; Neurons; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Signal Transduction; Synaptic Transmission

Topics: Alcoholism; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Ethanol; Models, Biological; Naltrexone; Narcotic Antagonists

Topics: Animals; Avoidance Learning; Brain Ischemia; Disease Models, Animal; Functional Laterality; Hippocampus; Injections, Intraventricular; Ischemic Preconditioning; Learning Disabilities; Lipopolysaccharides; Male; Maze Learning; Naltrexone; Neuroprotective Agents; Photic Stimulation; Random Allocation; Rats; Rats, Wistar; Reaction Time; Treatment Outcome

Topics: Analgesics; Animals; Disease Models, Animal; Female; Glyburide; Hyperalgesia; Metformin; Mice; Naltrexone; Neuralgia; Nociception; Psychomotor Performance; Receptors, Opioid

Topics: Aged; Analgesics, Opioid; Animals; Behavior, Animal; Cadaver; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Pruritus; Receptors, Bombesin; Receptors, Opioid, mu; Spinal Cord

Topics: Alcohol Abstinence; Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Ethanol; Food Preferences; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Naltrexone; Narcotic Antagonists; Species Specificity; Time Factors

Topics: Animals; Appetite Depressants; Bariatric Surgery; Benzazepines; Bupropion; Chronic Disease; Combined Modality Therapy; Diet, Reducing; Disease Models, Animal; Drug Combinations; Exercise; Fructose; Humans; Mood Disorders; Naltrexone; Obesity; Overweight; Phentermine; Psychotic Disorders; Randomized Controlled Trials as Topic

Topics: Adenosine; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Seizures; Xanthines

Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Flavanones; Flavonoids; Gastrointestinal Transit; Male; Maze Learning; Mice; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Measurement; Protein Binding; Receptors, Opioid, mu; Tritium; Visceral Pain

Topics: Acupuncture Analgesia; Acupuncture Points; Animals; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Naloxone; Naltrexone; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid; Time

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Male; Medial Forebrain Bundle; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Self Administration; Self Stimulation; Substance-Related Disorders

Topics: Acetamides; Alcohol Deterrents; Alcohol Drinking; Allosteric Regulation; Animals; Bacterial Proteins; Binge Drinking; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; GABA-B Receptor Agonists; Male; Mice; Naltrexone; Transcription Factors; Triazines

Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Depression; Disease Models, Animal; Dopamine; Gene Expression Regulation; Ketoprofen; Lactic Acid; Male; Medial Forebrain Bundle; Morphine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Stimulation; Time Factors

Topics: Acute Pain; Adenosine Monophosphate; Adenylyl Cyclases; Animals; Chronic Pain; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Isoflurane; Male; Mice; Naltrexone; Nociceptive Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome

Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enkephalins; Fentanyl; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu

Topics: Animals; Asphyxia; Benzamides; Blotting, Western; Brain Damage, Chronic; Cardiopulmonary Resuscitation; CREB-Binding Protein; Disease Models, Animal; Heart Arrest; Immunoenzyme Techniques; Male; Naltrexone; Neuroprotective Agents; Piperazines; Rats, Sprague-Dawley

Topics: Animals; Disease Models, Animal; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Neuralgia; Neuroglia; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyridines; Radiculopathy; Rats; Rats, Sprague-Dawley; Xanthines

Topics: Alcoholism; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Ethanol; Male; Naltrexone; Nicotine; Rats; Rats, Long-Evans; Self Administration; Smoking

Topics: Alcohol Drinking; Alcoholism; Animals; Animals, Newborn; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Hippocampus; Male; Naltrexone; Narcotic Antagonists; Rats, Sprague-Dawley; Schizophrenia

Topics: Abdominal Pain; Administration, Oral; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Diarrhea; Disease Models, Animal; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Exploratory Behavior; Gastrointestinal Motility; Injections, Intraperitoneal; Irritable Bowel Syndrome; Male; Mice; Motor Activity; Naltrexone; Receptors, Opioid, kappa; Receptors, Opioid, mu

Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Cholesterol; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Fatty Liver; Liver; Liver Circulation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Non-alcoholic Fatty Liver Disease; Proto-Oncogene Proteins c-bcl-2; Triglycerides; Tumor Necrosis Factor-alpha; Tunicamycin

Topics: Animals; Disease Models, Animal; Epilepsy, Absence; Female; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid; Reward; Sexual Behavior, Animal; Vocalization, Animal

Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dynorphins; Epigenesis, Genetic; Gene Expression Regulation; Hydroxamic Acids; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Pain Measurement; Spinal Cord; Vorinostat

Topics: Analgesics, Opioid; Animals; Body Weight; Conditioning, Operant; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Inhibition, Psychological; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Stimulation

Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord

Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Central Nervous System Depressants; Choice Behavior; Conditioning, Operant; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Seeking Behavior; Ethanol; Glutamic Acid; Guanfacine; Male; Naltrexone; Prefrontal Cortex; Pyramidal Cells; Rats, Wistar; Tissue Culture Techniques; Treatment Outcome

Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Exercise Test; Heart; HSP72 Heat-Shock Proteins; Male; Myocardial Reperfusion Injury; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Cerebrovascular Circulation; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression Regulation; Medulla Oblongata; Microinjections; Naltrexone; Narcotic Antagonists; Opioid Peptides; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Subarachnoid Hemorrhage; Time Factors

Topics: Adhesiveness; Administration, Ophthalmic; Animals; Calorimetry, Differential Scanning; Chickens; Chorioallantoic Membrane; Conjunctivitis; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Stability; Drug Storage; Gels; In Vitro Techniques; Microscopy, Electron, Scanning; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Surface Properties; Tensile Strength

Topics: Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Down-Regulation; Female; Hyperalgesia; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tibia

Topics: Animals; Axons; Baclofen; Charcot-Marie-Tooth Disease; Coculture Techniques; Disease Models, Animal; Down-Regulation; Drug Repositioning; Drug Therapy, Combination; Female; Gene Expression Regulation; Male; Mice; Myelin Proteins; Naltrexone; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Sciatic Neuropathy; Sorbitol

Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Hot Temperature; Hyperalgesia; Lumbar Vertebrae; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Pain, Postoperative; Piperidines; Posterior Horn Cells; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Remifentanil; Spinal Cord; Tissue Culture Techniques; Touch

Topics: Adaptation, Physiological; Animals; Binding, Competitive; Calcium Channels, L-Type; Disease Models, Animal; Enkephalins; Heart Failure; Ligands; Male; Myocardium; Naltrexone; Protein Binding; Protein Precursors; Radioligand Assay; Rats, Wistar; Receptors, Opioid, delta; Ryanodine Receptor Calcium Release Channel; Stroke Volume; Ventricular Function, Left

Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Freund's Adjuvant; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats, Sprague-Dawley; Receptors, Opioid, delta

Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gonadotropins, Pituitary; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reproduction; Substance-Related Disorders; Testosterone

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Pain; Pentazocine; Receptors, Opioid, kappa

Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Diclofenac; Disease Models, Animal; Female; Gyrus Cinguli; Lidocaine; Morphine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Rats; Rats, Inbred F344

Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Blood Alcohol Content; Choice Behavior; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug-Seeking Behavior; Indans; Male; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Reinforcement, Psychology; Species Specificity; Triazoles

Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Buprenorphine; Depression; Disease Models, Animal; Drug Therapy, Combination; Male; Maze Learning; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu

Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalins; Male; Mice, Inbred C57BL; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Protein Precursors; Receptors, Opioid, kappa; RNA, Messenger; Substance Withdrawal Syndrome

Topics: Administration, Intranasal; Alcoholism; Animals; Central Amygdaloid Nucleus; Central Nervous System Depressants; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Male; Motivation; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptors, Opioid, kappa; Self Administration; Substance Withdrawal Syndrome

Topics: Animals; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Functional Laterality; Male; Myalgia; Naltrexone; Narcotic Antagonists; Neural Pathways; Nociceptive Pain; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Receptors, Opioid, mu; Saline Solution, Hypertonic; Thalamic Nuclei; Time Factors

Topics: Animals; CD4-Positive T-Lymphocytes; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enkephalin, Methionine; Female; Mice; Multiple Sclerosis; Naltrexone; Narcotic Antagonists

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Arrestins; beta-Arrestins; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Guanidines; Isoquinolines; Male; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Motor Activity; Naltrexone; Pruritus; Receptors, Opioid, kappa

Topics: Analgesics; Analysis of Variance; Animals; Anxiety; Brain Injuries; Cognition Disorders; Disease Models, Animal; Enkephalins; Exploratory Behavior; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Recognition, Psychology; Silver Staining

Topics: Animals; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Histamine Agonists; Histamine Antagonists; Male; Mice; Morphine; Naltrexone; Pentylenetetrazole; Receptors, Histamine H1; Receptors, Histamine H3; Seizures

Topics: Animals; Baclofen; Behavior, Animal; Benzazepines; Benzodiazepines; Body Weight; Bulimia; Disease Models, Animal; Eating; Feeding Behavior; Female; Idazoxan; Lisdexamfetamine Dimesylate; Naltrexone; Olanzapine; Prazosin; Prodrugs; Raclopride; Rats; Rats, Wistar; Rolipram

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors

Topics: Animals; Cannabidiol; Cocaine; Conditioning, Classical; Cues; Disease Models, Animal; Male; Memory; Mental Recall; Morphine; Naltrexone; Rats; Rats, Wistar; Reward

Topics: Alcohol Abstinence; Alcohol Drinking; Analysis of Variance; Animals; Chlorides; Conditioning, Operant; Disease Models, Animal; Ethanol; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Manganese Compounds; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Time Factors

Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Electroshock; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Propranolol; Seizures; Time Factors

Topics: Alcoholism; Animals; Brain; Disease Models, Animal; Ethanol; Female; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid

Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Disease Models, Animal; Fluoxetine; Grooming; Heroin; Heroin Dependence; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Social Behavior; Time; Treatment Outcome

Topics: Analgesics, Opioid; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Tramadol

Topics: Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Decision Making; Disease Models, Animal; Gambling; Male; Naltrexone; Narcotic Antagonists; Rats

Topics: Animals; Binding, Competitive; CHO Cells; Cricetulus; Disease Models, Animal; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Mice; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Naltrexone; Neurons; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Longitudinal Studies; Magnetic Resonance Imaging; Naltrexone; Narcotic Antagonists; Rats

Topics: Animals; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ileum; Indomethacin; Intestinal Mucosa; Male; Naltrexone; Narcotic Antagonists; Rats; Sulfasalazine; Treatment Outcome

Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Disease Models, Animal; Diterpenes, Clerodane; Male; Mice; Mice, Inbred C57BL; Naltrexone; Receptors, Opioid, kappa; Reperfusion Injury

Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Choice Behavior; Delay Discounting; Disease Models, Animal; Eating; Feeding Behavior; Humans; Male; Naltrexone; Oxycodone; Rats; Reward; Time Factors

Topics: Animals; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Male; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Narcotics; Nociception; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Recovery of Function; Spinal Cord Injuries

Topics: Analgesia; Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Drug Tolerance; Gene Deletion; Hyperalgesia; Long-Term Potentiation; Mice; Mice, Knockout; Microglia; Morphine; Naltrexone; Nociception; Nociceptors; Pain, Postoperative; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Signal Transduction; Spinal Cord

Topics: Animals; Brain; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Exploratory Behavior; Illness Behavior; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Statistics as Topic

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal Pain; Analgesics; Analgesics, Opioid; Animals; Colon; Diarrhea; Disease Models, Animal; Gastrointestinal Motility; Gastrointestinal Transit; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Thebaine

Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Antipruritics; Arachidonate 12-Lipoxygenase; Behavior, Animal; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fatty Alcohols; Glycols; Male; Mice; Mice, Inbred ICR; Naltrexone; Pruritus; Receptors, Leukotriene B4; Signal Transduction; Tetrazoles; Video Recording

Topics: Animals; Biomarkers; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-12; Interleukin-6; Male; Mice; Naltrexone; Narcotic Antagonists; Weight Loss

Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Ethanol; Food Preferences; Male; Naltrexone; Narcotic Antagonists; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Analgesia; Analgesics; Animals; Cyclic AMP; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Hyperalgesia; Male; Mice; Naltrexone; Narcotic Antagonists; Nociceptors; Phosphodiesterase Inhibitors; Receptors, G-Protein-Coupled; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Time Factors

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Chronic Periodontitis; Disease Models, Animal; Male; Morphine; Naltrexone; Narcotic Antagonists; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa

Topics: Amygdala; Animals; Avoidance Learning; Behavior, Animal; C-Reactive Protein; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nerve Tissue Proteins; Retention, Psychology; Septal Nuclei; Substance Withdrawal Syndrome

Topics: Analysis of Variance; Animals; Association Learning; Behavior, Animal; Benzylidene Compounds; Conditioning, Classical; Disease Models, Animal; Male; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Statistics, Nonparametric

Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Neutrophils; Nitrates; Nitrites; Superoxides; Time Factors; Tumor Necrosis Factor-alpha

Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cold Temperature; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Naltrexone; Narcotic Antagonists; Random Allocation; Rats; Rats, Wistar; Reaction Time; Sexual Behavior, Animal; Stress, Psychological; Testosterone; Time Factors

Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Exploratory Behavior; Heroin; Heroin Dependence; Male; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Seizures

Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; Exploratory Behavior; Folic Acid; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Swimming

Topics: Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Extracellular Space; Hyperkinesis; Male; Morphinans; Naltrexone; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Schizophrenia; Serotonin; Spiro Compounds

Topics: Animals; Bile Ducts; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Genitalia, Male; Ligation; Luteinizing Hormone; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Opioid Peptides; Rats; Rats, Sprague-Dawley; Sperm Count; Sperm Motility; Testosterone

Topics: Angiogenesis Inducing Agents; Animals; Cholestasis, Extrahepatic; Common Bile Duct; Disease Models, Animal; Ligation; Male; Microvessels; Naltrexone; Narcotic Antagonists; Neovascularization, Physiologic; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid

Topics: Afferent Pathways; Analgesics, Opioid; Animals; Antipruritics; Biomarkers; Disease Models, Animal; Guanidines; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Nociceptors; p-Methoxy-N-methylphenethylamine; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pruritus; Receptors, Opioid, kappa; Sensory Receptor Cells; Spinal Cord; Spiro Compounds; Treatment Outcome

Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Dendritic Spines; Disease Models, Animal; Male; Microscopy, Confocal; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Neurons; Nucleus Accumbens; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Silver Staining; Substance Withdrawal Syndrome; Time Factors; Withania

Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors

Topics: Adrenergic Antagonists; Analgesics; Animals; Antidepressive Agents; Clonidine; Disease Models, Animal; Drug Interactions; Male; Mice; Mice, Inbred ICR; Morphine; Morpholines; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Reboxetine; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Animals; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Enkephalin, D-Penicillamine (2,5)-; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Pain Measurement; Receptors, Opioid, delta; Time Factors

Topics: Alcoholism; Animals; Aspartame; Conditioning, Operant; Disease Models, Animal; Female; Food Preferences; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Sweetening Agents

Topics: Analgesics; Animals; Disease Models, Animal; Functional Laterality; Male; Naltrexone; Narcotic Antagonists; Nitrous Oxide; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Random Allocation; Rats; Rats, Sprague-Dawley; Temperature; Time Factors; Treatment Outcome

Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Functional Laterality; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Propanolamines; Receptors, Adrenergic, beta-2; Sciatica; Time Factors

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Methadone; Morphine; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Time Factors

Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Corneal Diseases; Diabetes Complications; Disease Models, Animal; Enkephalin, Methionine; Epithelium, Corneal; Intraocular Pressure; Male; Naltrexone; Narcotic Antagonists; Rabbits; Regeneration; Time Factors

Topics: Animals; Biomedical Research; Brain Mapping; Disease Models, Animal; Genomics; Hot Temperature; Image Processing, Computer-Assisted; Kv Channel-Interacting Proteins; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Oxygen; Pain; Physical Stimulation; Repressor Proteins

Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Compounding; Hypericum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Perylene; Phorbol Esters; Phytotherapy; Protein Kinase C; Quercetin; Somatostatin; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Time Factors

Topics: Analgesics; Animals; Benzimidazoles; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Macaca mulatta; Male; Morphine; Naltrexone; Nociceptin; Opioid Peptides; Pain Measurement; Pain Threshold; Piperidines

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Time Factors

Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Central Nervous System; Cytokines; Disease Models, Animal; Female; Humans; Immunoglobulin E; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Stress, Psychological; Th2 Cells

Topics: Acamprosate; Alcohol Deterrents; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Disease Models, Animal; Disulfiram; Drug Design; Humans; Naltrexone; Narcotic Antagonists; Neuropeptides; Neuropharmacology; Neurotransmitter Agents; Receptors, Neurotransmitter; Taurine

Topics: Abdominal Pain; Animals; CD11b Antigen; Chymases; Colon; Delayed-Action Preparations; Disease Models, Animal; Gastrointestinal Transit; Hyperalgesia; Immunohistochemistry; Intestinal Mucosa; Male; Mast Cells; Microglia; Minocycline; Morphine; Naltrexone; Narcotic Antagonists; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Pressure; Rats; Rats, Wistar; Spinal Cord; Syndrome; Thioxanthenes; Time Factors; Ubiquitin Thiolesterase; Xanthones

Topics: 8,11,14-Eicosatrienoic Acid; Analgesics, Opioid; Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin

Topics: Animals; Antidepressive Agents; Anxiety Disorders; Brain; Depressive Disorder; Disease Models, Animal; Humans; Limbic System; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred WKY; Receptors, Opioid, kappa

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Exploratory Behavior; Male; Mental Recall; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reward; Stress, Psychological; Swimming

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Hindlimb; Hyperalgesia; Male; Mice; Morphine; Naltrexone; Pain Measurement; Pruritus; Skin

Topics: Alcohol Drinking; Animals; Baclofen; Disease Models, Animal; Ethanol; Excitatory Amino Acid Antagonists; GABA-B Receptor Agonists; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Pyridines; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Receptors, Opioid; Self Administration; Sucrose

Topics: Analgesics, Opioid; Animals; Anxiety; CA1 Region, Hippocampal; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Male; Maze Learning; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Animals; Antigens, Plant; Behavior, Animal; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Injections, Intradermal; Irritants; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Mucuna; Naltrexone; Narcotic Antagonists; Pain; Pruritus; Receptor, PAR-2; Receptors, Opioid, mu; Receptors, Thrombin; Time Factors

Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Disease Models, Animal; Estradiol; Female; Gonadal Steroid Hormones; Naltrexone; Narcotic Antagonists; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Opioid; Sympathetic Nervous System; Yohimbine

Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen; Disease Models, Animal; Hepatic Stellate Cells; Immunoblotting; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Morphinans; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

Topics: Animals; beta-Endorphin; Brain Stem; Disease Models, Animal; Enkephalin, Methionine; Male; Naltrexone; Narcotic Antagonists; Neuralgia; Pain Threshold; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Opioid

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid, mu; Seizures

Topics: Animals; Antiparkinson Agents; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Drug Interactions; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Macaca fascicularis; Male; Naltrexone; Narcotic Antagonists; Parkinsonian Disorders; Receptors, Opioid, mu

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Facial Pain; Formaldehyde; Ketoprofen; Male; Meloxicam; Mice; Naltrexone; Narcotic Antagonists; Stereoisomerism; Thiazines; Thiazoles

Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Mice, Nude; Naltrexone; Neovascularization, Pathologic; Ovarian Neoplasms; Paclitaxel; Treatment Outcome

Topics: Affect; Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Gyrus Cinguli; Hyperalgesia; Inflammation; Male; Naltrexone; Pain Management; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin

Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Locomotion; Male; Methadone; Naltrexone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Carrageenan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fentanyl; Hyperalgesia; Inflammation; Ketamine; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming; Time Factors

Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Routes; Immobility Response, Tonic; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome; Swimming; Time Factors

Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Male; Methadone; Naltrexone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Stereoisomerism

Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Electroacupuncture; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Paclitaxel; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Somatostatin

Topics: Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Naltrexone; Ovarian Neoplasms; Treatment Outcome

Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blotting, Western; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Diterpenes, Clerodane; Gastrointestinal Motility; Male; Mice; Naltrexone; Pain; Peroxidase; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, kappa; Salvia; Trinitrobenzenesulfonic Acid

Topics: Analgesics, Opioid; Animals; Brain; Cyclic AMP; Disease Models, Animal; Guanosine 5'-O-(3-Thiotriphosphate); Immunoprecipitation; Male; Naltrexone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu; Species Specificity; Spinal Cord

Topics: 5-Methoxytryptamine; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Naltrexone; Narcotic Antagonists; Pruritus; Rats; Rats, Wistar; Spinal Cord

Topics: Animals; Disease Models, Animal; Histamine; Mice; Mice, Inbred C57BL; Naltrexone; Oligopeptides; Peptide Fragments; Pruritus; Receptors, Thrombin; Touch

Topics: Analgesics, Opioid; Animals; Antipruritics; Disease Models, Animal; Face; Grooming; Injections, Intradermal; Male; Morphine; Mustard Plant; Naltrexone; Narcotic Antagonists; Pain; Plant Oils; Pruritus; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors

Topics: Animals; Conditioning, Psychological; Disease Models, Animal; Extinction, Psychological; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid, kappa; Recurrence; Risk Factors; Self Administration; Smoking; Stress, Psychological

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Female; Humans; Indans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naltrexone; Pattern Recognition, Visual; Piperidines; Presenilin-1; Random Allocation

Topics: Alcohol Drinking; Animals; Behavioral Symptoms; Cues; Disease Models, Animal; Dopamine; Drug Discovery; Ethanol; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Piperidines; Rats; Reward; Secondary Prevention; Substance Withdrawal Syndrome

Topics: Analysis of Variance; Anhedonia; Animals; Behavior, Animal; Disease Models, Animal; Mice; Mice, Knockout; Naltrexone; Object Attachment; Reactive Attachment Disorder; Receptors, Opioid, mu; Synaptic Transmission

Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Interleukin-6; Male; Naltrexone; Narcotic Antagonists; Pancreatitis; Peroxidase; Random Allocation; Rats; Rats, Wistar; Receptors, Opioid; Taurocholic Acid; Tumor Necrosis Factor-alpha

Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Ethanol; Exploratory Behavior; Gene Expression Regulation, Enzymologic; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, mu; RNA, Messenger; Time Factors

Topics: Alcohol Drinking; Animals; Benzazepines; Binge Drinking; Choice Behavior; Disease Models, Animal; Dopamine Antagonists; Ethanol; Male; Naltrexone; Narcotic Antagonists; Pyrimidines; Rats; Receptors, Corticotropin-Releasing Hormone; Self Administration

Topics: Analysis of Variance; Animals; Binge-Eating Disorder; Conditioning, Operant; Disease Models, Animal; Feeding Behavior; Male; Motivation; Naltrexone; Narcotic Antagonists; Opioid Peptides; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement, Psychology

Topics: Alcohol Drinking; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Ethanol; Goals; Male; Naltrexone; Rats; Rats, Long-Evans; Self Administration; Sucrose

Topics: Administration, Inhalation; Alcoholism; Animals; Appetitive Behavior; Behavior, Animal; Conditioning, Psychological; Corticotropin-Releasing Hormone; Cues; Disease Models, Animal; Drug Synergism; Electroshock; Ethanol; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Recurrence; Self Administration; Stress, Physiological

Topics: Analysis of Variance; Animals; Bile Ducts; Bone Remodeling; Cholestasis; Dental Alloys; Disease Models, Animal; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Nickel; Opioid Peptides; Orthodontic Wires; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics as Topic; Stress, Mechanical; Titanium; Tooth Movement Techniques; Treatment Outcome

Topics: Acute Disease; Analgesics, Opioid; Animals; Disease Models, Animal; Fentanyl; Male; Methadone; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Drug Interactions; Female; Injections, Spinal; Injections, Subcutaneous; Macaca mulatta; Male; Morphine; Naltrexone; Narcotic Antagonists; Pruritus; Receptors, Opioid, kappa

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; beta-Endorphin; Buprenorphine; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors

Topics: Animals; Behavior, Animal; Disease Models, Animal; Hindlimb; Injections, Intradermal; Male; Naltrexone; Narcotic Antagonists; Pruritus; Rats; Rats, Sprague-Dawley; Reflex; Serotonin

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation, Physiological; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Osmolar Concentration; Planarians; Reaction Time; Receptors, Opioid, kappa; Substance Withdrawal Syndrome

Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome

Topics: Adenylyl Cyclases; Animals; Brain; Disease Models, Animal; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Receptors, Opioid, mu; Signal Transduction; Substance Withdrawal Syndrome; Sulfur Radioisotopes

Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Grooming; Head Movements; Male; Mastication; Morphine; Mustard Plant; Naltrexone; Narcotic Antagonists; Neural Pathways; Nociceptors; Pain; Plant Extracts; Plant Oils; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Temporomandibular Joint Disorders; Trigeminal Caudal Nucleus

Topics: Animals; Antiemetics; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Injections, Intraperitoneal; Kaolin; Male; Morphine; Naltrexone; Narcotic Antagonists; Ondansetron; Pica; Quaternary Ammonium Compounds; Rats; Rats, Wistar

Topics: Alcoholism; Animals; Behavior, Addictive; Disease Models, Animal; Humans; Naltrexone; Societies, Medical; United States

Topics: Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentylenetetrazole; Piperidines; Pyrazoles; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Statistics, Nonparametric; Time Factors

Topics: Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Escape Reaction; Helplessness, Learned; Immobilization; Immunohistochemistry; Limbic System; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Stress, Physiological

Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Behavior, Addictive; Disease Models, Animal; Endorphins; Ethanol; Euphoria; Humans; Naltrexone; Receptors, Dopamine D2; Receptors, Opioid; Secondary Prevention; Taurine

Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Cholestasis, Extrahepatic; Disease Models, Animal; Drug Therapy, Combination; Gastrointestinal Transit; Injections, Intraperitoneal; Injections, Subcutaneous; Intestine, Small; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone

Topics: Animals; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentylenetetrazole; Reaction Time; Seizures

Topics: Adjuvants, Immunologic; Animals; beta-Endorphin; Cell Proliferation; Chickens; Disease Models, Animal; Enkephalins; Gene Expression; Macrophages, Peritoneal; Male; Melatonin; Naltrexone; Narcotic Antagonists; Opioid Peptides; Peritonitis; Pro-Opiomelanocortin; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen; Thioglycolates

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dyskinesias; Female; Levodopa; Macaca fascicularis; Motor Activity; Naltrexone; Narcotic Antagonists; Ovariectomy; Parkinsonian Disorders; Statistics, Nonparametric; Time Factors

Topics: Age Factors; Animals; Antipruritics; Autoimmune Diseases; Behavior, Animal; Chlorpheniramine; Dermis; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunoglobulin E; Immunoglobulin G; Male; Mice; Mice, Inbred ICR; Mice, Inbred MRL lpr; Mice, Inbred Strains; Morphinans; Naltrexone; Pruritus; Receptors, Opioid, kappa; Sex Factors; Spiro Compounds

Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; Chronic Disease; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Piperazines; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatica; Somatostatin; Sulfur Isotopes; Time Factors; Tranquilizing Agents

Topics: Acetic Acid; Analgesics, Opioid; Analysis of Variance; Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Isomerism; Male; Maze Learning; Memory Disorders; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Pentazocine; Propylamines; Receptors, Opioid, kappa; Receptors, sigma; Scopolamine

Topics: Amphetamine-Related Disorders; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Methamphetamine; Mice; Naltrexone; Narcotic Antagonists

Topics: Aconitum; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Injections, Intraperitoneal; Injections, Spinal; Male; Naltrexone; Pain Measurement; Pain Threshold; Plant Tubers; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sciatic Nerve; Sciatica

Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Bile Ducts; Cardiomyopathies; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoproterenol; Ligation; Male; Myocardial Contraction; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Opioid Peptides; Papillary Muscles; Phenylephrine; Rats; Rats, Sprague-Dawley

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic Agents; AIDS-Related Complex; Amphetamine; Analgesics, Non-Narcotic; Animals; Antiparkinson Agents; Behavior, Animal; Carrier Proteins; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Functional Laterality; Homer Scaffolding Proteins; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oxidopamine; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation

Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Opioid; Sciatic Nerve

Topics: Animals; Behavior, Animal; Blotting, Western; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Gene Expression; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Solitary Nucleus; Substance Withdrawal Syndrome; Time Factors

Topics: Alcoholism; Animals; Anxiety; Disease Models, Animal; Individuality; Male; Mice; Motor Activity; Naltrexone; Narcotic Antagonists; Reproducibility of Results; Self Administration

Topics: Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Tolerance; Female; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Rats; Rats, Inbred F344; Rats, Long-Evans; Rats, Sprague-Dawley; Sex Factors; Species Specificity

Topics: Alcohol Drinking; Analysis of Variance; Animals; Behavior, Animal; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Administration Routes; Drug Interactions; Eating; Ethanol; Exploratory Behavior; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Receptors, Opioid; Receptors, Opioid, mu; Time Factors

Topics: Animals; Anxiety Disorders; Astrocytes; Brain Tissue Transplantation; Cells, Cultured; Cerebral Cortex; Chronic Disease; Culture Media, Conditioned; Disease Models, Animal; Gliosis; Gyrus Cinguli; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Neuralgia; Pain, Intractable; Peripheral Nervous System Diseases; Receptors, Opioid, delta; Sciatic Neuropathy; Stem Cells

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileus; Laparotomy; Male; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol-Induced Disorders, Nervous System; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anticonvulsants; Brain; Central Nervous System Depressants; Disease Models, Animal; Drug Interactions; Drug Synergism; Ethanol; Male; Naltrexone; Receptors, Opioid, kappa; Seizures; Species Specificity; Substance Withdrawal Syndrome; Treatment Outcome

Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Conjunctiva; Cornea; Disease Models, Animal; DNA; Epithelium; Follow-Up Studies; Homeostasis; Male; Mitosis; Naltrexone; Narcotic Antagonists; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley; Time Factors

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Parkinson Disease; Prosencephalon; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reserpine; Tritium

Topics: Alcohol Drinking; Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Depressants; Conditioning, Operant; Cues; Disease Models, Animal; Ethanol; Gene Expression Regulation; Male; Naltrexone; Narcotic Antagonists; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reaction Time

Topics: Aging; Analysis of Variance; Animals; Attention; Cognition Disorders; Disease Models, Animal; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley

Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Gingiva; Injections; Injections, Subcutaneous; Leukocyte Count; Male; Morphine; Naltrexone; Narcotic Antagonists; Neutrophils; Periodontal Attachment Loss; Periodontal Diseases; Rats; Rats, Sprague-Dawley; Receptors, Opioid

Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Behavior, Animal; Central Nervous System Depressants; Darkness; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drinking Behavior; Ethanol; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Piperazines; Reproducibility of Results; Self Administration; Signal Transduction

Topics: Analgesics, Opioid; Animals; Apoptosis; Biological Factors; Cholestasis; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Hepatocytes; Liver; Naltrexone; Narcotic Antagonists; Oxidative Stress; Rats

Topics: Analysis of Variance; Animals; Body Temperature; Body Weight; Calorimetry, Indirect; Cardiac Catheterization; Disease Models, Animal; Drug Evaluation, Preclinical; Energy Intake; Energy Metabolism; Injections, Intravenous; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Obesity; Rats; Rats, Zucker; Receptors, Opioid, kappa; Respiration; Telemetry

Topics: Acid Sensing Ion Channels; Analgesics; Animals; Area Under Curve; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalins; Membrane Proteins; Mice; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Pain; Pain Measurement; Peptides; Protein Precursors; Reaction Time; Sodium Channels; Spider Venoms; Spinal Cord; Time Factors

Topics: Animals; Anticonvulsants; Bile Ducts; Cannabinoid Receptor Modulators; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Ligation; Male; Mice; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Time Factors

Topics: Animals; Cell Migration Assays, Leukocyte; Cytokines; Disease Models, Animal; Interleukin-6; Intestinal Mucosa; Larva; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Naltrexone; Narcotic Antagonists; Nematospiroides dubius; Nitric Oxide; Opioid Peptides; Specific Pathogen-Free Organisms; Strongylida Infections

Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression; Inflammation; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Narcotic Antagonists; Opioid Peptides; Physical Exertion; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid; RNA, Messenger; Time Factors

Topics: Analgesics, Opioid; Animals; Brain Chemistry; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, Methionine; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Male; Morphine Dependence; Naltrexone; Narcotic Antagonists; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu

Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carrageenan; Dipyrone; Disease Models, Animal; Hyperalgesia; Inflammation; Injections, Intralesional; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Rats, Wistar; Research Design; Time Factors

Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Bilirubin; Biomarkers; Cholestasis; Corn Oil; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Infusions, Intravenous; Intubation, Gastrointestinal; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid; Seizures; Time Factors

Topics: Amphetamine; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Benzoxazines; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Interactions; Morpholines; Naltrexone; Naphthalenes; Narcotic Antagonists; Planarians; Substance Withdrawal Syndrome; Time Factors

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Methionine; FMRFamide; Gene Expression Regulation; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors

Topics: Alcohol Deterrents; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ethanol; Male; Naltrexone; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Saccharin; Self Administration; Sweetening Agents; Thiophenes

Topics: Alcoholism; Alleles; Animals; Clinical Trials as Topic; Disease Models, Animal; Genetic Markers; Genomics; Humans; Macaca mulatta; Naltrexone; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid, mu

Topics: Alcohol Drinking; Alcoholism; Analysis of Variance; Animals; Behavior, Animal; beta-Endorphin; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Female; Naltrexone; Narcotic Antagonists; Rats; Time Factors

Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Addictive; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Female; Male; Naltrexone; Rats; Reinforcement Schedule

Topics: Alcohol Drinking; Animals; Behavior, Animal; Bilirubin; Brain; Disease Models, Animal; Drinking; Liver Cirrhosis; Male; Naloxone; Naltrexone; Narcotic Antagonists; Prothrombin Time; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, mu; Thioacetamide; Time Factors

Topics: Animals; Disease Models, Animal; Ligation; Liver Cirrhosis, Biliary; Male; Mesentery; Naltrexone; Narcotic Antagonists; Nitrates; Nitrites; Phenylephrine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstriction; Vasoconstrictor Agents

Topics: Administration, Oral; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Hyperalgesia; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Neuralgia; Oxycodone; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Signal Transduction; Spinal Nerves

Topics: Animals; Behavior, Animal; Disease Models, Animal; Enkephalin, Leucine-2-Alanine; Hyperalgesia; Ligation; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuralgia; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Nerves; Thalamic Nuclei

Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Partial Agonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Sulfur Radioisotopes; Thalamus; Time Factors

Topics: Animals; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

Topics: Adrenocorticotropic Hormone; Animals; Disease Models, Animal; Endorphins; Humans; Naltrexone; Peptide Fragments; Rats; Social Behavior; Social Behavior Disorders

Topics: Animals; Disease Models, Animal; Electroshock; Endorphins; Epilepsy; Female; Gerbillinae; Male; Models, Neurological; Naltrexone; Pentylenetetrazole; Seizures

Topics: Animals; Behavior, Animal; Differential Threshold; Disease Models, Animal; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve; Time Factors

Topics: Alcoholism; Animals; Disease Models, Animal; Ethanol; Humans; Isoquinolines; Macaca mulatta; Male; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Self Administration; Tetrahydroisoquinolines

Topics: Analgesia; Analysis of Variance; Animals; Behavior, Animal; Blood-Brain Barrier; Disease Models, Animal; Drug Interactions; Hindlimb; Male; Naltrexone; Narcotic Antagonists; Nerve Compression Syndromes; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sciatic Nerve; Vocalization, Animal

Topics: Animals; Biological Assay; Disease Models, Animal; Dizocilpine Maleate; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peptide Fragments; Phencyclidine; Receptors, Opioid, mu; Spinal Cord; Substance P

Topics: Acute Disease; Animals; Cholestasis; Disease Models, Animal; Enkephalins; Flow Cytometry; Leukocytes; Lymphocytes; Male; Monocytes; Naltrexone; Neutrophils; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

Topics: Adrenal Cortex; Animals; Cerebral Cortex; Corticosterone; Cycloheximide; Dexamethasone; Disease Models, Animal; Disease Susceptibility; Electroencephalography; Epilepsy; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred DBA; Mifepristone; Morphine; Naltrexone

Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Disease Models, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vocalization, Animal

Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepines; Carbolines; Catecholamines; Corticosterone; Diazepam; Disease Models, Animal; Female; GABA-A Receptor Agonists; Glucocorticoids; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mifepristone; Nadolol; Naltrexone; Neurosecretory Systems; Oxidopamine; Phentolamine; Picrotoxin; Propranolol; Receptors, GABA-A; Spleen; Sympathetic Nervous System

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Haplorhini; Humans; Naltrexone; Narcotic Antagonists; Rats; Serotonin Antagonists; Serotonin Receptor Agonists; Taurine; Thyrotropin-Releasing Hormone

Topics: Acepromazine; Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Ethology; Female; Horse Diseases; Horses; Humans; Naltrexone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Opioid Peptides; Paroxetine; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereotyped Behavior; Stress, Psychological

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Binding, Competitive; Disease Models, Animal; Drug Implants; Exons; Gene Targeting; Immune System; Immunosuppression Therapy; Interleukin-2; Ligands; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Knockout; Mitogens; Morphine; Naltrexone; Organ Size; Phagocytosis; Receptors, Opioid, mu; Spleen; Substance-Related Disorders; Thymidine; Thymus Gland; Tumor Necrosis Factor-alpha

Topics: Action Potentials; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Peptide Fragments; Perforant Pathway; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Status Epilepticus

Topics: Animals; Anti-Arrhythmia Agents; beta-Endorphin; Disease Models, Animal; Dynorphins; Enkephalin, Leucine-2-Alanine; Heart; Immobilization; Ligands; Morphine; Myocardial Infarction; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Stress, Physiological; Ventricular Fibrillation

Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hyperalgesia; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Nervous System Diseases; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Somatostatin; Time Factors; Vocalization, Animal

Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzofurans; Biogenic Monoamines; Clonidine; Disease Models, Animal; Drug Combinations; Drug Synergism; Locomotion; Male; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Prazosin; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reserpine; Yohimbine

Topics: Analgesics, Opioid; Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Maleate; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Nociceptin; Opioid Peptides; Psychomotor Performance; Rats; Scopolamine

Topics: Animals; Behavior, Animal; Disease Models, Animal; Female; Fetus; Humans; Maternal-Fetal Exchange; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pregnancy; Rats; Substance Withdrawal Syndrome

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Naltrexone; Narcotic Antagonists; Rats; Reproducibility of Results; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome; Taurine

Topics: Animals; Avoidance Learning; Behavior, Animal; Chronic Disease; Conditioning, Psychological; Depression; Disease Models, Animal; Fear; Feeding Behavior; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Opioid Peptides; Random Allocation; Rats; Rats, Wistar; Single-Blind Method; Stress, Psychological

Topics: Age Factors; Amygdala; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Locus Coeruleus; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid-Related Disorders; Periaqueductal Gray; Quaternary Ammonium Compounds; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome

Topics: Androstanes; Animals; Benzimidazoles; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Drug Administration Routes; Male; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Lew; Receptors, Opioid; Specific Pathogen-Free Organisms; Substance P

Topics: Adrenocorticotropic Hormone; Animals; Apoptosis; beta-Endorphin; Blood Pressure; Corticosterone; Cytokines; Disease Models, Animal; Hemodynamics; Interleukin-1; Interleukin-10; Interleukin-6; Lung; Male; Naltrexone; Narcotic Antagonists; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Spleen; Time Factors; Tumor Necrosis Factor-alpha

Topics: Animals; Behavior, Animal; Brain Stem; Disease Models, Animal; Immunotoxins; Ligation; Male; Medulla Oblongata; Microinjections; N-Glycosyl Hydrolases; Naltrexone; Neuralgia; Neurons; Oligopeptides; Opioid Peptides; Pain Measurement; Physical Stimulation; Plant Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Recombinant Fusion Proteins; Ribosome Inactivating Proteins, Type 1; Saporins; Spinal Nerves

Topics: Alcohol Deterrents; Animals; Arginine; Bile Ducts; Cholestasis; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Ligation; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Opioid Peptides; Rats; Stomach Ulcer

Topics: Analgesics, Opioid; Analysis of Variance; Animals; Blood Pressure; Disease Models, Animal; Drug Interactions; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Threshold; Rats; Rats, Inbred SHR; Rats, Inbred WKY

Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Callithrix; Disease Models, Animal; Drug Therapy, Combination; Dyskinesias; Female; Hypokinesia; Levodopa; Male; Morphinans; Motor Activity; Naltrexone; Narcotic Antagonists; Parkinsonian Disorders; Posture; Receptors, Opioid, delta; Receptors, Opioid, mu

Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cardiac Surgical Procedures; Coronary Circulation; Disease Models, Animal; Drug Evaluation, Preclinical; Enkephalin, D-Penicillamine (2,5)-; Heart Arrest, Induced; Hypothermia, Induced; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Naltrexone; Narcotic Antagonists; Organ Size; Oxygen Consumption; Rabbits; Receptors, Opioid, delta; Recovery of Function; Stroke Volume; Ventricular Pressure

Topics: Animals; Antipruritics; Chlorpheniramine; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Ketotifen; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Pruritus; Receptors, Opioid, kappa; Spiro Compounds; Substance P

Topics: Animals; Cholestasis; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures

Topics: Conditioning, Operant; Disease Models, Animal; Heroin Dependence; Humans; Male; Naltrexone; Placebos; Reinforcement Schedule; Self Administration

Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain Injuries; Disease Models, Animal; Energy Metabolism; Magnesium; Magnetic Resonance Spectroscopy; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains

Topics: Animals; beta-Endorphin; Disease Models, Animal; Dose-Response Relationship, Drug; Endorphins; Female; Hemodynamics; Naloxone; Naltrexone; Narcotic Antagonists; Papio; Shock, Hemorrhagic; Time Factors

Topics: Animals; beta-Endorphin; Disease Models, Animal; Endorphins; Graft Survival; Immunity, Cellular; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naltrexone; Neoplasm Transplantation; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; T-Lymphocytes; Time Factors

Topics: Animals; Brain Ischemia; Cats; Cerebrovascular Disorders; Consciousness; Diprenorphine; Disease Models, Animal; Male; Morphinans; Movement; Naloxone; Naltrexone; Pupil; Sensation