naltrexone and Crohn Disease

naltrexone has been researched along with Crohn Disease in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's14 (87.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Lie, MRKL; Paulides, E; van der Woude, CJ1
Berlau, DJ; Patten, DK; Schultz, BG1
Raknes, G; Simonsen, P; Småbrekke, L1
Chande, N; MacDonald, JK; Nguyen, TM; Parker, CE; Segal, D1
Feng, J; Griffin, N; Li, Z; Shan, F; You, Y1
Jackson, WE; Lashner, BA; Rizk, M1
Chande, N; Macdonald, JK; Segal, D1
Weinstock, LB1
Handberg, G; Plesner, KB; Vægter, HB1
Abdel-Salam, LO; Kamel, MM; Khattab, A; Osman, AS; Tawfik, DI; Tolba, HM1
Alkhouri, N; Kaplan, B; Mahajan, L; Mayacy, S; Shannon, A1
Bingaman, SI; Mauger, DT; McGovern, CO; Mukherjee, A; Ruggiero, F; Smith, JP; Zagon, IS1
Giverhaug, T; Raknes, G1
McLaughlin, PJ; Zagon, IS1
Bingaman, SI; Evans, R; Field, D; Mauger, DT; Smith, JP1
Bingaman, S; Mauger, D; Rogosnitzky, M; Smith, JP; Stock, H; Zagon, IS1

Reviews

5 review(s) available for naltrexone and Crohn Disease

ArticleYear
The Safety and Efficacy of Low-Dose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohn's Disease, and Other Chronic Pain Disorders.
    Pharmacotherapy, 2018, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chronic Pain; Crohn Disease; Dose-Response Relationship, Drug; Fibromyalgia; Humans; Inflammation; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Quality of Life

2018
Low dose naltrexone for induction of remission in Crohn's disease.
    The Cochrane database of systematic reviews, 2018, 04-01, Volume: 4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Crohn Disease; Humans; Induction Chemotherapy; Intention to Treat Analysis; Naltrexone; Randomized Controlled Trials as Topic

2018
Low-dose naltrexone (LDN): A promising treatment in immune-related diseases and cancer therapy.
    International immunopharmacology, 2018, Volume: 61

    Topics: Analgesics, Opioid; Animals; Autoimmunity; Crohn Disease; Drug Dosage Calculations; Humans; Immunologic Factors; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Neoplasms; Off-Label Use; Receptors, Opioid; Substance Abuse Treatment Centers

2018
Low dose naltrexone for induction of remission in Crohn's disease.
    The Cochrane database of systematic reviews, 2014, Feb-21, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Crohn Disease; Humans; Induction Chemotherapy; Naltrexone; Randomized Controlled Trials as Topic

2014
[Low dose naltrexone for treatment of pain].
    Ugeskrift for laeger, 2015, Oct-09, Volume: 177, Issue:43

    Topics: Analgesics, Opioid; Crohn Disease; Fibromyalgia; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Pain

2015

Trials

3 trial(s) available for naltrexone and Crohn Disease

ArticleYear
Low-dose naltrexone for the induction of remission in patients with mild to moderate Crohn's disease: protocol for the randomised, double-blinded, placebo-controlled, multicentre LDN Crohn study.
    BMJ open, 2022, 04-08, Volume: 12, Issue:4

    Topics: Crohn Disease; Humans; Inflammation; Inflammatory Bowel Diseases; Multicenter Studies as Topic; Naltrexone; Randomized Controlled Trials as Topic; Remission Induction

2022
Therapy with the opioid antagonist naltrexone promotes mucosal healing in active Crohn's disease: a randomized placebo-controlled trial.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:7

    Topics: Adult; Aged; Colonoscopy; Crohn Disease; Fatigue; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Remission Induction; Severity of Illness Index; Treatment Outcome; Young Adult

2011
Safety and tolerability of low-dose naltrexone therapy in children with moderate to severe Crohn's disease: a pilot study.
    Journal of clinical gastroenterology, 2013, Volume: 47, Issue:4

    Topics: Administration, Oral; Adolescent; Age Factors; Child; Crohn Disease; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Pennsylvania; Pilot Projects; Quality of Life; Remission Induction; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Treatment Outcome

2013

Other Studies

8 other study(ies) available for naltrexone and Crohn Disease

ArticleYear
The Effect of Low-Dose Naltrexone on Medication in Inflammatory Bowel Disease: A Quasi Experimental Before-and-After Prescription Database Study.
    Journal of Crohn's & colitis, 2018, May-25, Volume: 12, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Databases, Factual; Drug Prescriptions; Female; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Norway; Off-Label Use; Tumor Necrosis Factor-alpha

2018
Avoiding narcotics in Crohn's disease.
    Journal of clinical gastroenterology, 2013, Volume: 47, Issue:4

    Topics: Crohn Disease; Female; Humans; Male; Naltrexone; Narcotic Antagonists

2013
Naltrexone therapy for Crohn's disease and ulcerative colitis.
    Journal of clinical gastroenterology, 2014, Volume: 48, Issue:8

    Topics: Crohn Disease; Female; Humans; Male; Naltrexone; Narcotic Antagonists

2014
Evaluation of therapeutic effect of low dose naltrexone in experimentally-induced Crohn's disease in rats.
    Neuropeptides, 2016, Volume: 59

    Topics: Animals; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ileum; Indomethacin; Intestinal Mucosa; Male; Naltrexone; Narcotic Antagonists; Rats; Sulfasalazine; Treatment Outcome

2016
Low-dose naltrexone for treatment of duodenal Crohn's disease in a pediatric patient.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:9

    Topics: Adolescent; Crohn Disease; Dose-Response Relationship, Drug; Duodenal Diseases; Female; Humans; Naltrexone; Narcotic Antagonists; Treatment Outcome

2010
[Naltrexone--high expectations to low dosages].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2011, May-06, Volume: 131, Issue:8

    Topics: Crohn Disease; Dose-Response Relationship, Drug; Humans; Multiple Sclerosis; Naltrexone; Narcotic Antagonists; Treatment Outcome

2011
Targeting opioid signaling in Crohn's disease: new therapeutic pathways.
    Expert review of gastroenterology & hepatology, 2011, Volume: 5, Issue:5

    Topics: Analgesics, Opioid; B-Lymphocytes; Cell Proliferation; Crohn Disease; Humans; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Signal Transduction; T-Lymphocytes

2011
Low-dose naltrexone therapy improves active Crohn's disease.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:4

    Topics: Adult; Blood Sedimentation; C-Reactive Protein; Crohn Disease; Endoscopy, Gastrointestinal; Female; Gastrointestinal Agents; Humans; Male; Middle Aged; Naltrexone; Pilot Projects; Prospective Studies; Quality of Life; Surveys and Questionnaires; Treatment Outcome

2007