naltrexone and Cocaine-Related Disorders

naltrexone has been researched along with Cocaine-Related Disorders in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (12.96)	18.2507
2000's	20 (37.04)	29.6817
2010's	22 (40.74)	24.3611
2020's	5 (9.26)	2.80

Authors

Authors	Studies
Graham, DP; Hamon, SC; Hillhouse, M; Kosten, TR; Lawson, WB; Ling, W; Nielsen, DA; Nielsen, EM; Rotrosen, J; Saxon, AJ; Settles-Reaves, BD; Shmueli-Blumberg, D; Shores-Wilson, K; Trivedi, MH; Walker, R	1
Cippitelli, A; Toll, L; Zribi, G	1
Bachtell, RK; Brown, KT; Levis, SC; Levy, C; O'Neill, CE; Rice, KC; Watkins, LR	1
Kenny, PJ; O'Brien, CP; Pierce, RC; Swinford-Jackson, SE; Unterwald, EM; Vanderschuren, LJMJ	1
Ayers, C; Chan, B; Freeman, M; Kansagara, D; Kondo, K; Korthuis, PT; Paynter, R	1
George, O; Kallupi, M; Martin-Fardon, R; Matzeu, A; Schweitzer, P	1
Buchholz, J; Saxon, AJ	1
Carson, RE; Chang, D; Foltin, R; Grassetti, A; Huang, Y; Lin, SF; Martinez, D; Matuskey, D; Nabulsi, N; Ropchan, J; Salling, M; Slifstein, M; Urban, N; Zheng, MQ	1
Briand, LA; Graziane, NM; Kauer, JA; Pierce, RC; Polter, AM	1
Askalsky, P; Berkower, EL; Comer, SD; Cooper, ZD; Foltin, RW; Haney, M; Jones, JD; Manubay, JM; Martinez, D; Mogali, S; Pines, A; Roux, P; Rubin, E; Saccone, PA; Sullivan, MA; Vosburg, SK; Walker, EA	1
Grabowski, J; Green, CE; Lindsay, JA; Moeller, FG; Rathnayaka, NS; Schmitz, JM; Stotts, AL	1
Aklin, WM; Bigelow, GE; DeFulio, A; Donlin, WD; Dunn, K; Everly, JJ; Fingerhood, M; Leoutsakos, JM; Nuzzo, PA; Silverman, K; Umbricht, A	1
Grosshans, M; Kiefer, F; Mutschler, J	1
Willyard, C	1
Eans, SO; Ganno, ML; Hunkele, A; Le Rouzic, V; Majumdar, S; Marrone, GF; McLaughlin, JP; Pasternak, GW; Subrath, JJ; Váradi, A	1
Sushchyk, S; Wang, JB; Xi, ZX	1
Ang, A; Annon, J; Brigham, GS; Church, S; Dawes, M; Drexler, K; Hasson, A; Hillhouse, MP; Knox, PC; Korthuis, PT; Lawson, W; Ling, W; Liu, DS; Matthews, AG; McCormack, J; Mooney, LJ; Ross, S; Rotrosen, J; Saxon, AJ; Schuman, C; Sparenborg, S; Swafford, W; Thomas, CM; Wiest, K	1
Correia, M; Deakin, JF; Elliott, R; Ersche, KD; Flechais, RS; Lingford-Hughes, AR; McGonigle, J; Murphy, A; Nutt, DJ; Orban, C; Passamonti, L; Paterson, LM; Reed, LJ; Riccelli, R; Robbins, TW; Sahakian, BJ; Savulich, G; Smith, DG; Suckling, J; Tait, R; Taylor, EM	1
Batki, SL; Dimmock, JA; Leontieva, L; Ploutz-Snyder, R	1
Achat-Mendes, C; Platt, DM; Rowlett, JK; Spealman, RD; Valdez, GR	1
Kampman, KM; Oslin, DW; Pettinati, HM; Plebani, JG; Tirado, CF; Volpicelli, JR	1
Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Spealman, RD	1
Amato, L; Davoli, M; Pani, PP; Trogu, E; Vacca, R; Vecchi, S	1
Kjome, KL; Kramer, LA; Liu, S; Ma, L; Moeller, FG; Narayana, PA; Rathnayaka, N; Schmitz, JM; Steinberg, JL	1
Beardsley, PM; Carroll, FI; Howard, JL; Pollard, GT	1
Koob, GF; Misra, KK; Schlosburg, JE; Vendruscolo, LF; Wee, S	1
Aklin, WM; Bigelow, GE; Fingerhood, M; Lejuez, CW; Severtson, SG; Silverman, K; Umbricht, A	1
Hasson, A; Hillhouse, M; Lindblad, R; Ling, W; McCormack, J; Mooney, LJ; Nielsen, S; Saxon, A; Stablein, D; Thomas, C	1
Aklin, WM; Bigelow, GE; Defulio, A; Donlin, WD; Dunn, KE; Everly, JJ; Fingerhood, M; Leoutsakos, JM; Nuzzo, PA; Silverman, K; Umbricht, A	1
Modesto-Lowe, V; Van Kirk, J	1
Kleber, HD	1
Kosten, TR; McCance-Katz, FE; Oliveto, A; Petrakis, I; Singha, A; Sofuoglu, M	1
Hagan, JJ; Heidbreder, CA	1
Gerrits, MA; Kuzmin, AV; van Ree, JM	1
O'Brien, CP	1
Fantoma, A; Gerra, G; Zaimovic, A	1
Antonilli, L; Cioce, AM; Giudici, FD; Grassi, MC; Nencini, P	1
Aicardi, G; Burattini, C; Burbassi, S; Cervo, L	1
Carroll, K; Levinson, C; Nich, C; Petrakis, I; Poling, J; Ralevski, E; Rounsaville, B	1
McGeary, JE; Miranda, R; Monti, PM; Rohsenow, DJ	1
Dackis, CA; Kampman, KM; Lynch, KG; O'Brien, CP; Oslin, DW; Pettinati, HM; Suh, JJ	1
Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Spealman, RD; Valdez, GR	1
Dackis, C; Kampman, KM; Lynch, KG; O'Brien, CP; Pettinati, HM; Rabinowitz, AR; Xie, H	1
Stitzer, ML; Vandrey, R	1
Braida, D; Gori, E; Paladini, E; Sala, M	1
Bauer, LO; Burleson, JA; Hersh, D; Kranzler, HR; Modesto-Lowe, V	1
Barringer, TM; Cavallaro, CA; Hubbell, CL; Mendez, JJ; Pabello, NG; Reid, LD	1
Hersh, D; Kranzler, HR; Van Kirk, JR	1
Borg, L; Gunduz, M; Ho, A; Kreek, MJ; Schluger, J	1
Kampman, KM; O'Brien, CP; Oslin, DW; Pettinati, HM; Volpicelli, JR; Wolf, AL	1
Hersh, D; Kranzler, HR; Mulgrew, CL; Van Kirk, J	1
Mello, NK; Negus, SS	1
Bornstein, G; Church, SH; Nunes, EV; Rothenberg, JL; Sullivan, MA	1
Dhopesh, V; Fudala, PJ; Yu, E	1

Reviews

9 review(s) available for naltrexone and Cocaine-Related Disorders

Article	Year
A systematic review and meta-analysis of medications for stimulant use disorders in patients with co-occurring opioid use disorders. Drug and alcohol dependence, 2020, 11-01, Volume: 216 Topics: Analgesics, Opioid; Antidepressive Agents; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Female; Humans; Methadone; Naltrexone; Opioid-Related Disorders	2020
Medications to treat cocaine use disorders: current options. Current opinion in psychiatry, 2019, Volume: 32, Issue:4 Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Central Nervous System Stimulants; Cocaine-Related Disorders; Disulfiram; Humans; Naltrexone	2019
Disulfiram for the treatment of cocaine dependence. The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1 Topics: Cocaine-Related Disorders; Disulfiram; Humans; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic	2010
Clinical uses of naltrexone: a review of the evidence. Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:3 Topics: Alcoholism; Animals; Behavior, Addictive; Cocaine-Related Disorders; Feeding and Eating Disorders; Humans; Naltrexone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Schizophrenia; Self-Injurious Behavior; Substance-Related Disorders; Tobacco Use Disorder	2002
Pharmacologic treatments for heroin and cocaine dependence. The American journal on addictions, 2003, Volume: 12, Issue:s2 Topics: Buprenorphine; Clonidine; Cocaine-Related Disorders; Comorbidity; Heroin Dependence; Humans; Mental Disorders; Methadone; Methadyl Acetate; Naltrexone; Narcotic Antagonists; Narcotics	2003
Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving. Current opinion in pharmacology, 2005, Volume: 5, Issue:1 Topics: Alcoholism; Clinical Trials as Topic; Cocaine-Related Disorders; Humans; Naltrexone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Structure-Activity Relationship; Substance-Related Disorders; Tobacco Use Disorder	2005
Anticraving medications for relapse prevention: a possible new class of psychoactive medications. The American journal of psychiatry, 2005, Volume: 162, Issue:8 Topics: Alcoholism; Behavior, Addictive; Bupropion; Cocaine-Related Disorders; Disulfiram; Humans; Naltrexone; Nicotine; Psychotherapy; Psychotropic Drugs; Secondary Prevention; Substance-Related Disorders; Tobacco Use Disorder	2005
Contingency management: utility in the treatment of drug abuse disorders. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:4 Topics: Behavior Therapy; Buprenorphine; Cocaine-Related Disorders; Humans; Motivation; Naltrexone; Narcotic Antagonists; Patient Compliance; Receptors, Opioid, mu; Reinforcement, Psychology; Reward; Substance Abuse Detection; Substance Abuse Treatment Centers; Substance-Related Disorders; Treatment Outcome	2008
Interactions between kappa opioid agonists and cocaine. Preclinical studies. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Discrimination Learning; Humans; Naloxone; Naltrexone; Receptors, Opioid, kappa; Self Administration	2000

Trials

22 trial(s) available for naltrexone and Cocaine-Related Disorders

Article	Year
Moderation of buprenorphine therapy for cocaine dependence efficacy by variation of the Prodynorphin gene. European journal of clinical pharmacology, 2022, Volume: 78, Issue:6 Topics: Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Enkephalins; Humans; Injections, Intramuscular; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Protein Precursors	2022
Effects of acute oral naltrexone on the subjective and physiological effects of oral D-amphetamine and smoked cocaine in cocaine abusers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:12 Topics: Administration, Oral; Adult; Cardiovascular System; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dextroamphetamine; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Smoking	2013
A two-phased screening paradigm for evaluating candidate medications for cocaine cessation or relapse prevention: modafinil, levodopa-carbidopa, naltrexone. Drug and alcohol dependence, 2014, Mar-01, Volume: 136 Topics: Adolescent; Adult; Benzhydryl Compounds; Carbidopa; Central Nervous System Stimulants; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Data Interpretation, Statistical; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Agents; Female; Humans; Levodopa; Male; Middle Aged; Modafinil; Motivational Interviewing; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Patient Compliance; Secondary Prevention; Treatment Outcome; Young Adult	2014
Employment-based reinforcement of adherence to oral naltrexone in unemployed injection drug users: 12-month outcomes. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2015, Volume: 29, Issue:2 Topics: Adult; Cocaine-Related Disorders; Drug Users; Employment; Female; Follow-Up Studies; Humans; Injections; Male; Medication Adherence; Middle Aged; Naltrexone; Opioid-Related Disorders; Reinforcement, Psychology; Secondary Prevention; Treatment Outcome; Unemployment	2015
Buprenorphine + naloxone plus naltrexone for the treatment of cocaine dependence: the Cocaine Use Reduction with Buprenorphine (CURB) study. Addiction (Abingdon, England), 2016, Volume: 111, Issue:8 Topics: Administration, Oral; Adult; Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Treatment Outcome	2016
Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery. Translational psychiatry, 2017, 03-07, Volume: 7, Issue:3 Topics: Adult; Adult Survivors of Child Adverse Events; Alcoholism; Amygdala; Brain; Case-Control Studies; Cocaine-Related Disorders; Cross-Over Studies; Cues; Double-Blind Method; Female; Functional Neuroimaging; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid-Related Disorders; Prefrontal Cortex; Substance-Related Disorders; Young Adult	2017
Combined effects of alcohol and hepatitis C: a secondary analysis of alcohol use biomarkers and high-risk behaviors from two medication trials for alcohol dependence. Addictive behaviors, 2010, Volume: 35, Issue:2 Topics: Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Cocaine-Related Disorders; Female; gamma-Glutamyltransferase; Hepatitis C; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Risk Factors; Risk-Taking; Transferrin	2010
Working memory fMRI activation in cocaine-dependent subjects: association with treatment response. Psychiatry research, 2010, Mar-30, Volume: 181, Issue:3 Topics: Adult; Amphetamine; Analysis of Variance; Benzhydryl Compounds; Brain; Brain Mapping; Carbidopa; Central Nervous System Stimulants; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Dopamine Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Mathematics; Memory Disorders; Memory, Short-Term; Middle Aged; Modafinil; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Oxygen	2010
Risk-taking propensity as a predictor of induction onto naltrexone treatment for opioid dependence. The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8 Topics: Administration, Oral; Adult; Baltimore; Cocaine-Related Disorders; Conditioning, Operant; Female; Heroin Dependence; Humans; Male; Medication Adherence; Middle Aged; Naltrexone; Narcotic Antagonists; Odds Ratio; Opioid-Related Disorders; Patient Acceptance of Health Care; Personality Assessment; Psychometrics; Rehabilitation, Vocational; Risk-Taking; Sheltered Workshops; Substance Abuse Detection; Substance Abuse, Intravenous	2012
Cocaine use reduction with buprenorphine (CURB): rationale, design, and methodology. Contemporary clinical trials, 2013, Volume: 34, Issue:2 Topics: Administration, Sublingual; Adolescent; Adult; Aged; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Treatment Outcome; Young Adult	2013
Employment-based reinforcement of adherence to oral naltrexone treatment in unemployed injection drug users. Experimental and clinical psychopharmacology, 2013, Volume: 21, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Aged; Cocaine-Related Disorders; Employment; Female; Humans; Male; Medication Adherence; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Dropouts; Reinforcement, Psychology; Substance Abuse, Intravenous; Substance-Related Disorders; Workplace	2013
Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:4 Topics: Adult; Area Under Curve; Behavior, Addictive; Blood Pressure; Cocaine-Related Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Isradipine; Male; Naltrexone	2003
Short-term efficacy of Disulfiram or Naltrexone in reducing positive urinalysis for both cocaine and cocaethylene in cocaine abusers: a pilot study. Pharmacological research, 2007, Volume: 55, Issue:2 Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Disulfiram; Humans; Naltrexone; Narcotic Antagonists; Patient Compliance; Pilot Projects; Time Factors; Treatment Outcome	2007
Naltrexone and disulfiram in patients with alcohol dependence and current depression. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2 Topics: Alcohol Deterrents; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Comorbidity; Connecticut; Depressive Disorder, Major; Disulfiram; Double-Blind Method; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Gastrointestinal Diseases; Humans; Male; Massachusetts; Middle Aged; Naltrexone; Narcotic Antagonists; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Stress Disorders, Post-Traumatic; Treatment Outcome; Veterans	2007
Family history and antisocial traits moderate naltrexone's effects on heavy drinking in alcoholics. Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:3 Topics: Adult; Age of Onset; Alcohol Drinking; Alcoholism; Antisocial Personality Disorder; Cocaine-Related Disorders; Comorbidity; Double-Blind Method; Family; Female; Genetic Predisposition to Disease; Humans; Male; Marijuana Abuse; Naltrexone	2007
Gender differences with high-dose naltrexone in patients with co-occurring cocaine and alcohol dependence. Journal of substance abuse treatment, 2008, Volume: 34, Issue:4 Topics: Adolescent; Adult; Aged; Alcoholism; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Sex Factors	2008
A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependence. Addictive behaviors, 2008, Volume: 33, Issue:5 Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Cocaine-Related Disorders; Disulfiram; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Treatment Outcome	2008
Effects of naltrexone on cue-elicited craving for alcohol and cocaine. Drug and alcohol dependence, 1997, Volume: 49, Issue:1 Topics: Adolescent; Adult; Affect; Alcoholism; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Psychiatric Status Rating Scales; Severity of Illness Index; Surveys and Questionnaires; Time Factors; Visual Perception	1997
Naltrexone treatment of comorbid alcohol and cocaine use disorders. Psychopharmacology, 1998, Volume: 139, Issue:1-2 Topics: Adult; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Cocaine-Related Disorders; Compliance; Double-Blind Method; Female; Humans; Male; Naltrexone	1998
Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:1 Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Dynorphins; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Prolactin; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Characteristics; Time Factors	1999
The effects of naltrexone on alcohol and cocaine use in dually addicted patients. Journal of substance abuse treatment, 1999, Volume: 16, Issue:2 Topics: Adult; Alcohol Drinking; Alcoholism; Ambulatory Care; Cocaine-Related Disorders; Combined Modality Therapy; Comorbidity; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Prevalence; Psychotherapy; Treatment Outcome	1999
The validity of self-reported cocaine use in two groups of cocaine abusers. Journal of consulting and clinical psychology, 1999, Volume: 67, Issue:1 Topics: Adult; Carbamazepine; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Interview, Psychological; Male; Naltrexone; Predictive Value of Tests; Psychometrics; Reproducibility of Results; Self Disclosure; Substance Abuse Detection	1999

Other Studies

23 other study(ies) available for naltrexone and Cocaine-Related Disorders

Article	Year
PPL-103: A mixed opioid partial agonist with desirable anti-cocaine properties. Progress in neuro-psychopharmacology & biological psychiatry, 2022, 12-20, Volume: 119 Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Humans; Naltrexone; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration	2022
Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking. Psychopharmacology, 2023, Volume: 240, Issue:7 Topics: Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Lipopolysaccharides; Naltrexone; Rats; Rats, Sprague-Dawley; Self Administration; Toll-Like Receptor 4	2023
The Persistent Challenge of Developing Addiction Pharmacotherapies. Cold Spring Harbor perspectives in medicine, 2021, 11-01, Volume: 11, Issue:11 Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Bupropion; Central Nervous System Stimulants; Cocaine-Related Disorders; Drug Therapy; Humans; Naltrexone; Narcotic Antagonists; Nicotinic Agonists; Smoking Cessation Agents; Substance-Related Disorders; Varenicline	2021
Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:5 Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Drug Interactions; Dynorphins; Excitatory Postsynaptic Potentials; Extinction, Psychological; Male; Microinjections; Miniature Postsynaptic Potentials; Naltrexone; Orexins; Paraventricular Hypothalamic Nucleus; Rats; Reward; Self Administration	2018
Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:10 Topics: Adult; Brain; Carbon Radioisotopes; Case-Control Studies; Choice Behavior; Cocaine; Cocaine Smoking; Cocaine-Related Disorders; Dynorphins; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neostriatum; Piperazines; Positron-Emission Tomography; Pyrrolidines; Receptors, Opioid, kappa; Stress, Psychological	2019
Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity. Neuron, 2013, Mar-06, Volume: 77, Issue:5 Topics: Animals; Cocaine-Related Disorders; Dopaminergic Neurons; Drug-Seeking Behavior; Extinction, Psychological; In Vitro Techniques; Long-Term Potentiation; Microinjections; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Opioid, kappa; Recurrence; Self Administration; Stress, Psychological; Swimming; Synapses; Ventral Tegmental Area	2013
Treatment of cocaine craving with as-needed nalmefene, a partial κ opioid receptor agonist: first clinical experience. International clinical psychopharmacology, 2015, Volume: 30, Issue:4 Topics: Adult; Behavior, Addictive; Cocaine-Related Disorders; Craving; Drug Partial Agonism; Female; Humans; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Recurrence; Time Factors; Treatment Outcome	2015
Pharmacotherapy: Quest for the quitting pill. Nature, 2015, Jun-25, Volume: 522, Issue:7557 Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins	2015
Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior. ACS chemical neuroscience, 2015, Nov-18, Volume: 6, Issue:11 Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Morphinans; Naltrexone; Nociception; Nuclear Receptor Subfamily 1, Group F, Member 1; Random Allocation; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Spatial Behavior	2015
Combination of Levo-Tetrahydropalmatine and Low Dose Naltrexone: A Promising Treatment for Prevention of Cocaine Relapse. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:2 Topics: Animals; Berberine Alkaloids; beta-Endorphin; Cocaine-Related Disorders; Drug Therapy, Combination; Drug-Seeking Behavior; Hypothalamus; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Pro-Opiomelanocortin; Rats; Rats, Wistar; Recurrence; Self Administration; Substance Withdrawal Syndrome	2016
Negative symptoms are associated with less alcohol use, craving, and "high" in alcohol dependent patients with schizophrenia. Schizophrenia research, 2008, Volume: 105, Issue:1-3 Topics: Adult; Alcohol Drinking; Alcoholism; Behavior, Addictive; Cocaine-Related Disorders; Cognition Disorders; Comorbidity; Diagnostic and Statistical Manual of Mental Disorders; Euphoria; Female; Humans; Male; Marijuana Abuse; Naltrexone; Narcotic Antagonists; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index	2008
Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazine. Psychopharmacology, 2009, Volume: 204, Issue:3 Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Female; Heroin; Injections, Intravenous; Macaca mulatta; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance Abuse, Intravenous	2009
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms. Psychopharmacology, 2010, Volume: 210, Issue:2 Topics: Animals; Benzofurans; Citalopram; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Fluoxetine; Ligands; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Saimiri; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin; Serotonin 5-HT1 Receptor Agonists	2010
Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diure Psychopharmacology, 2010, Volume: 210, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine-Related Disorders; Diuresis; Dose-Response Relationship, Drug; Male; Naltrexone; Pain; Piperidines; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Self Administration; Tetrahydroisoquinolines	2010
A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence. Science translational medicine, 2012, Aug-08, Volume: 4, Issue:146 Topics: Animals; Buprenorphine; Cocaine; Cocaine-Related Disorders; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Substance Withdrawal Syndrome	2012
Reinstatement of cocaine-seeking behavior in rats is attenuated following repeated treatment with the opioid receptor antagonist naltrexone. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:3 Topics: Animals; Behavior, Animal; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Recurrence; Substance Abuse, Intravenous	2005
Naltrexone and buprenorphine combination in the treatment of opioid dependence. Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:6 Topics: Adult; Affect; Buprenorphine; Cocaine; Cocaine-Related Disorders; Female; Heroin Dependence; Humans; Liver; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Psychiatric Status Rating Scales; Substance Abuse Detection; Survival Analysis	2006
Effects of naltrexone on cocaine- and sucrose-seeking behaviour in response to associated stimuli in rats. The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:1 Topics: Animals; Behavior, Animal; Cocaine-Related Disorders; Cues; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Sucrose	2008
Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2 Topics: Animals; Behavior, Addictive; Benzofurans; Clonidine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Male; Naltrexone; Norepinephrine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri; Self Administration; Stress, Psychological	2007
Naltrexone, naltrindole, and CTOP block cocaine-induced sensitization to seizures and death. Peptides, 1997, Volume: 18, Issue:8 Topics: Animals; Cocaine-Related Disorders; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures; Somatostatin	1997
Responding for rewarding brain stimulation: cocaine and isradipine plus naltrexone. Pharmacology, biochemistry, and behavior, 1998, Volume: 61, Issue:2 Topics: Analysis of Variance; Animals; Brain; Calcium Channel Blockers; Cocaine-Related Disorders; Drug Therapy, Combination; Electric Stimulation; Fluoxetine; Isradipine; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Valproic Acid	1998
Concurrent substance use and outcome in combined behavioral and naltrexone therapy for opiate dependence. The American journal of drug and alcohol abuse, 2001, Volume: 27, Issue:3 Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Anxiety Agents; Behavior Therapy; Benzodiazepines; Cocaine-Related Disorders; Female; Humans; Male; Marijuana Smoking; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Abuse Detection; Treatment Outcome	2001
Conservative management with naltrexone of an iatrogenic methadone overdose in an opiate-naive patient. Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:2 Topics: Alcoholism; Cocaine-Related Disorders; Diagnosis, Dual (Psychiatry); Drug Overdose; Humans; Male; Medication Errors; Methadone; Middle Aged; Naltrexone; Schizophrenia	2002