naltrexone and Atrophy, Muscular, Peroneal

naltrexone has been researched along with Atrophy, Muscular, Peroneal in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Adams, D; Amato, A; Attarian, S; Brannagan, TH; Carter, G; Casanovas, C; de Visser, M; Felice, K; Magy, L; Péréon, Y; Statland, JM; Stino, A; Tard, C; Thomas, FP; Van Damme, P; Verhamme, C; Walk, D; Walter, MC; Young, P1
Adam, J; Barrantes-Freer, A; Bartl, M; Boussicault, L; Brureau, A; Cohen, D; Czesnik, D; Ewers, D; Hajj, R; Jäger, K; Laffaire, J; Linhoff, L; Nabirotchkin, S; Nave, KA; Primas, G; Prukop, T; Quintes, S; Rinaudo, P; Schmidt, J; Schwab, MH; Sereda, MW; Wernick, S; Winter, L; Zschüntzsch, J1
Adam, J; Cohen, D; Ewers, D; Hajj, R; Kungl, T; Mroczek, M; Nabirotchkin, S; Nave, KA; Prukop, T; Sereda, MW; Stenzel, J; Wernick, S1
Bertrand, V; Boucard, A; Cholet, N; Chumakov, I; Cohen, D; Foucquier, J; Glibert, F; Graudens, E; Guedj, M; Hajj, R; Laffaire, J; Mandel, J; Milet, A; Nabirotchkin, S; Nave, KA; Pereira, Y; Primas, G; Sereda, MW; Vial, E1
Al-Moussawi, M; Attarian, S; Bertrand, V; Bossi, L; Boudiaf, L; Chumakov, I; Cohen, D; Dubourg, O; Franques, J; Funalot, B; Ghorab, K; Gilbert, W; Gonnaud, PM; Guedj, M; Hajj, R; Lacour, A; Leclair-Visonneau, L; Lefebvre, MN; Lehert, P; Magot, A; Magy, L; Mandel, J; Micallef, J; Milet, A; Nabirotchkin, S; Péréon, Y; Pouget, J; Preudhomme, M; Scart-Grès, C; Stojkovic, T; Tiffreau, V; Vallat, JM1

Trials

2 trial(s) available for naltrexone and Atrophy, Muscular, Peroneal

ArticleYear
A double-blind, placebo-controlled, randomized trial of PXT3003 for the treatment of Charcot-Marie-Tooth type 1A.
    Orphanet journal of rare diseases, 2021, 10-16, Volume: 16, Issue:1

    Topics: Baclofen; Charcot-Marie-Tooth Disease; Double-Blind Method; Humans; Naltrexone; Sorbitol

2021
An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.
    Orphanet journal of rare diseases, 2014, Dec-18, Volume: 9

    Topics: Adult; Baclofen; Charcot-Marie-Tooth Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Sorbitol

2014

Other Studies

3 other study(ies) available for naltrexone and Atrophy, Muscular, Peroneal

ArticleYear
Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats.
    Journal of neuroscience research, 2020, Volume: 98, Issue:10

    Topics: Animals; Baclofen; Charcot-Marie-Tooth Disease; Coculture Techniques; Demyelinating Diseases; Drug Synergism; Drug Therapy, Combination; Female; Male; Myelin Proteins; Naltrexone; Neural Conduction; Neuromuscular Junction; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Sorbitol

2020
Early short-term PXT3003 combinational therapy delays disease onset in a transgenic rat model of Charcot-Marie-Tooth disease 1A (CMT1A).
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Animals; Axons; Baclofen; Charcot-Marie-Tooth Disease; Demyelinating Diseases; Disease Models, Animal; Drug Combinations; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Muscle Weakness; Myelin Proteins; Naltrexone; Neural Conduction; Phosphatidylinositol 3-Kinases; Proof of Concept Study; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Schwann Cells; Signal Transduction; Sorbitol

2019
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy.
    Orphanet journal of rare diseases, 2014, Dec-10, Volume: 9

    Topics: Animals; Axons; Baclofen; Charcot-Marie-Tooth Disease; Coculture Techniques; Disease Models, Animal; Down-Regulation; Drug Repositioning; Drug Therapy, Combination; Female; Gene Expression Regulation; Male; Mice; Myelin Proteins; Naltrexone; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Sciatic Neuropathy; Sorbitol

2014