naltrexone and Anxiety

naltrexone has been researched along with Anxiety in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.94)	18.7374
1990's	9 (13.24)	18.2507
2000's	24 (35.29)	29.6817
2010's	29 (42.65)	24.3611
2020's	4 (5.88)	2.80

Authors

Authors	Studies
Araya, EI; Baggio, DF; Barroso, AR; Chichorro, JG; Koren, LO; Turnes, JM; Zanoveli, JM	1
Arnett, PA; McLaughlin, PJ; Odom, LB; Orehek, S; Thomas, GA; Zagon, IS	1
Nagase, H; Oka, JI; Saitoh, A; Yamada, D; Yanagisawa, S; Yanagita, S; Yoshizawa, K	1
Iio, K; Nagase, H; Nishida, M; Saitoh, A; Sakamoto, K; Yamada, D; Yamanaka, N	1
Amstislavskaya, TG; de Abreu, MS; Demin, KA; Galstyan, DS; Giacomini, ACVV; Kalueff, AV; Kolesnikova, TO; Petersen, EV; Strekalova, T; Zabegalov, KN	1
Bujarski, S; Courtney, KE; London, ED; Ray, LA; Roche, DJO; Shoptaw, S; Worley, MJ	1
Bidlack, JM; Callaghan, CK; Dean, RL; Deaver, DR; Knapp, BI; O'Mara, SM; Rouine, J	1
Nagase, H; Oka, JI; Saitoh, A; Sugiyama, A; Yamada, M	1
Carroll, KM; DeVito, EE; Frankforter, TL; Kiluk, BD; Nich, C; Sofuoglu, M; Yip, SW	1
Kayashima, S; Nagase, H; Oka, JI; Saitoh, A; Soda, A; Yamada, M; Yoshizawa, K	1
Krajci, P; Kunoe, N; Latif, ZE; Opheim, A; Šaltyte Benth, J; Sharma-Haase, K; Solli, KK; Tanum, L	1
Gillett, K; Harshberger, E; Valdez, GR	1
Becker, A; Grecksch, G; Havemann-Reinecke, U; Höllt, V; Maurer, HH; Meyer, MR; Neurath, H; Schröder, H; Stolt, AC; Ziebolz, N	1
Crawford, EF; George, O; Koob, GF; Park, PE; Schlosburg, JE; Vendruscolo, LF; Whitfield, TW	1
Nagase, H; Oka, J; Saitoh, A; Sugiyama, A; Yamada, M	1
Gibula-Bruzda, E; Izdebski, J; Kotlinska, JH; Marszalek-Grabska, M; Witkowska, E	1
Hanks, AN; Hughes, ZA; Mejias-Aponte, C; O'Donnell, P; Scott, L; Tejeda, HA	1
Becker, JA; Clesse, D; Diaz, J; Kieffer, BL; Le Merrer, J; Meirsman, AC; Pellissier, LP	1
Lesniak, A; Lipkowski, AW; Misicka, A; Pick, CG; Sacharczuk, M	1
Aldrich, JV; Huang, P; Liu-Chen, LY; Parry, C; Tunis, J; Yakovleva, T	1
Hang, A; Liu, JG; Long, Y; Shu, XH; Wang, Q; Wang, YJ; Zan, GY	1
Ficek, J; Golda, S; Korostynski, M; Piechota, M; Przewlocki, R; Szklarczyk, K	1
Blokhina, E; Burakov, A; Bushara, N; Krupitsky, E; Masalov, D; Palatkin, V; Pecoraro, A; Romanova, T; Tsoy-Podosenin, M; Tyurina, A; Verbitskaya, E; Wahlgren, V; Woody, G; Yaroslavtseva, T; Zvartau, E	1
Drummond, PD; Vo, L	1
Gaburro, S; Herzog, H; Rosskothen, I; Schunk, E; Schwarzer, C; Singewald, N; Wittmann, W	1
Antapasis, J; Bolaños Guzmán, CA; Herrera, CM; Poveromo, LB; Wiley, MD	1
Brocardo, PS; Budni, J; Lobato, KR; Rodrigues, AL; Santos, AR	1
Andreoli, S; Bria, P; De Filippis, R; Di Giannantonio, M; Di Nicola, M; Janiri, L; Martinotti, G; Mazza, M; Moroni, N; Pomponi, M; Pozzi, G; Reina, D; Romanelli, R; Tedeschi, D	1
Brissett, DI; van Rijn, RM; Whistler, JL	1
Pescatore, KA; Randall-Thompson, JF; Unterwald, EM	1
Salari, AA; Solati, J; Zarrindast, MR	1
Solati, J	1
Harshberger, E; Valdez, GR	1
Amaya, MI; de Gortari, P; Estrada-Camarena, E; Mejía-Mauríes, S; Mengod, G; Morales-Mulia, M; Sollozo-Dupont, I	1
Bailey, SJ; Casal-Dominguez, JJ; Clark, M; Husbands, SM; Traynor, JR	1
Chen, X; Kirouac, GJ; Li, S; Li, Y; Rogala, B	1
Berrendero, F; Maldonado, R	1
Amikishieva, AV; Kudriavtseva, NN; Obut, TA; Ovsiukova, MV	1
Guaza, C; Llorente, R; Marco, EM; Moreno, E; Pérez-Alvarez, L; Viveros, MP	1
Kamei, J; Onodera, K; Saitoh, A; Yoshikawa, Y	1
Guen, SL; Kieffer, BL; Nieto, MM; Noble, F; Roques, BP	1
Kaneko, C; Kuzumaki, N; Matsuzawa, K; Miyoshi, K; Nagumo, Y; Nakajima, M; Nanjo, K; Narita, M; Suzuki, T; Yamazaki, M	1
De Jong, CJ	1
Bakalkin, G; Kuzmin, A; Madjid, N; Ogren, SO; Terenius, L	1
Sher, L	1
Boerngen de Lacerda, R; Fachin-Scheit, DJ; Frozino Ribeiro, A; Oliveira Goeldner, F; Pigatto, G	1
Hoshaw, BA; Perrine, SA; Unterwald, EM	1
Bell, JR; Haber, PS; Morley, KC; Phung, N; Reid, SC; Richardson, K; Sannibale, C; Teesson, M; Thomson, C; Weltman, M	1
al'Absi, M; Bruehl, S; Burns, JW; Chung, OY; France, CR; France, J; Harju, A	1
Cottone, P; Sabino, V; Steardo, L; Zorrilla, EP	1
Doebrick, C; Fox, H; Hong, KI; Hyman, SM; Sinha, R	1
Drummond, PD; Frew, AK	1
Davidson, D; Gulliver, SB; Longabaugh, R; Wirtz, PW	1
de Cabo de la Vega, C; Paz Viveros, M; Pujol, A	1
Maier, SF; Silbert, LH; Woodmansee, WW	1
Arntz, A; Janssen, SA	2
Krois, S; Liberto, JG; O'Brien, J; Oslin, D	1
Agmo, A; Belzung, C	1
Cole, JC; Little, HJ; Littleton, JM	1
Goto, K; Ishige, A; Komatsu, Y; Omiya, Y	1
Messier, C; Wall, PM	1
Befort, K; Chluba, J; Dierich, A; Filliol, D; Gavériaux-Ruff, C; Ghozland, S; Kieffer, BL; LeMeur, M; Maldonado, R; Martin, M; Matthes, HW; Simonin, F; Valverde, O	1
Zhang, HT	1
Calenco-Choukroun, G; Daugé, V; Féger, J; Gacel, G; Roques, BP	1
Lee, C; Rodgers, RJ	1
Peachey, JE	1
Duka, T; Stephens, DN	1

Reviews

2 review(s) available for naltrexone and Anxiety

Article	Year
Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra. Pharmacology, biochemistry, and behavior, 2021, Volume: 207 Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish	2021
Alcoholism and suicidal behavior: a clinical overview. Acta psychiatrica Scandinavica, 2006, Volume: 113, Issue:1 Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Antidepressive Agents, Tricyclic; Anxiety; Comorbidity; Depressive Disorder, Major; Humans; Hydroxyindoleacetic Acid; Naltrexone; Narcotic Antagonists; Personality Disorders; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Suicide; Suicide, Attempted; Taurine	2006

Article

Year

Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra.

Pharmacology, biochemistry, and behavior, 2021, Volume: 207

Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish

2021

Alcoholism and suicidal behavior: a clinical overview.

Acta psychiatrica Scandinavica, 2006, Volume: 113, Issue:1

Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Antidepressive Agents, Tricyclic; Anxiety; Comorbidity; Depressive Disorder, Major; Humans; Hydroxyindoleacetic Acid; Naltrexone; Narcotic Antagonists; Personality Disorders; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Suicide; Suicide, Attempted; Taurine

2006

Trials

11 trial(s) available for naltrexone and Anxiety

Article	Year
Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug and alcohol dependence, 2018, 11-01, Volume: 192 Topics: Administration, Oral; Adult; Anhedonia; Anxiety; Depression; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Patient Dropouts; Treatment Outcome	2018
Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone: A Randomized Clinical Trial and Follow-up Study. JAMA psychiatry, 2019, 02-01, Volume: 76, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Anxiety; Buprenorphine, Naloxone Drug Combination; Comorbidity; Delayed-Action Preparations; Depression; Female; Follow-Up Studies; Humans; Injections, Intramuscular; Male; Middle Aged; Naltrexone; Opioid-Related Disorders; Sleep Initiation and Maintenance Disorders; Young Adult	2019
Anhedonia, depression, anxiety, and craving in opiate dependent patients stabilized on oral naltrexone or an extended release naltrexone implant. The American journal of drug and alcohol abuse, 2016, Volume: 42, Issue:5 Topics: Administration, Oral; Adult; Anhedonia; Anxiety; Craving; Delayed-Action Preparations; Depression; Double-Blind Method; Drug Implants; Female; Humans; Male; Naltrexone; Opioid-Related Disorders; Treatment Outcome; Young Adult	2016
Pregabalin versus naltrexone in alcohol dependence: a randomised, double-blind, comparison trial. Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:9 Topics: Adult; Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Anticonvulsants; Anxiety; Calcium Channel Blockers; Double-Blind Method; Female; gamma-Aminobutyric Acid; Hostility; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Obsessive-Compulsive Disorder; Pregabalin; Severity of Illness Index; Substance Withdrawal Syndrome	2010
Naltrexone versus acamprosate in the treatment of alcohol dependence: A multi-centre, randomized, double-blind, placebo-controlled trial. Addiction (Abingdon, England), 2006, Volume: 101, Issue:10 Topics: Acamprosate; Adult; Alcohol Deterrents; Alcohol-Related Disorders; Anxiety; Australia; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Patient Compliance; Placebos; Secondary Prevention; Taurine; Treatment Outcome	2006
Anger management style and endogenous opioid function: is gender a moderator? Journal of behavioral medicine, 2007, Volume: 30, Issue:3 Topics: Adult; Anger; Anxiety; Depression; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain Threshold; Sex Factors; Skin; Statistics as Topic	2007
Stress and drug-cue-induced craving in opioid-dependent individuals in naltrexone treatment. Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:2 Topics: Adult; Anxiety; Behavior, Addictive; Blood Pressure; Cues; Emotions; Female; Heart Rate; Humans; Imagery, Psychotherapy; Male; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Stress, Psychological	2007
Naltrexone's suppressant effects on drinking are limited to the first 3 months of treatment. Psychopharmacology, 2007, Volume: 194, Issue:1 Topics: Adolescent; Adult; Aged; Alcoholism; Anxiety; Double-Blind Method; Drug Administration Schedule; Fatigue; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nausea; Patient Compliance; Time Factors; Treatment Outcome; Withholding Treatment	2007
Anxiety and pain: attentional and endorphinergic influences. Pain, 1996, Volume: 66, Issue:2-3 Topics: Adolescent; Adult; Anxiety; Attention; Electric Stimulation; Endorphins; Female; Galvanic Skin Response; Humans; Middle Aged; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Phobic Disorders	1996
Tolerability of naltrexone in treating older, alcohol-dependent patients. The American journal on addictions, 1997,Summer, Volume: 6, Issue:3 Topics: Age Factors; Alcoholism; Anxiety; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Sleep	1997
No interactive effects of naltrexone and benzodiazepines on pain during phobic fear. Behaviour research and therapy, 1999, Volume: 37, Issue:1 Topics: Adolescent; Adult; Alprazolam; Anxiety; Benzodiazepines; Drug Interactions; Electroshock; Female; Humans; Middle Aged; Naltrexone; Pain; Pain Measurement; Pain Threshold; Phobic Disorders	1999

Other Studies

55 other study(ies) available for naltrexone and Anxiety

Article	Year
Blockade of kappa opioid receptors reduces mechanical hyperalgesia and anxiety-like behavior in a rat model of trigeminal neuropathic pain. Behavioural brain research, 2022, 01-24, Volume: 417 Topics: Animals; Anxiety; Central Amygdaloid Nucleus; Chronic Pain; Disease Models, Animal; Hyperalgesia; Male; Naltrexone; Nociception; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Trigeminal Neuralgia	2022
Low-dose naltrexone reduced anxiety in persons with multiple sclerosis during the COVID-19 pandemic. International immunopharmacology, 2022, Volume: 113, Issue:Pt B Topics: Anxiety; COVID-19 Drug Treatment; Humans; Multiple Sclerosis; Naltrexone; Pandemics	2022
Selective agonists of the δ-opioid receptor, KNT-127 and SNC80, act differentially on extinction learning of contextual fear memory in mice. Neuropharmacology, 2019, 12-01, Volume: 160 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzamides; Conditioning, Psychological; Extinction, Psychological; Fear; Learning; Male; Memory; Mice; Morphinans; Motor Activity; Naltrexone; Piperazines; Receptors, Opioid, delta	2019
A selective delta opioid receptor agonist SNC80, but not KNT-127, induced tremor-like behaviors via hippocampal glutamatergic system in mice. Brain research, 2021, 04-15, Volume: 1757 Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Benzamides; Hippocampus; Insular Cortex; Mice; Morphinans; Motor Activity; Naltrexone; Piperazines; Receptors, Opioid, delta	2021
Naltrexone moderates the relationship between cue-induced craving and subjective response to methamphetamine in individuals with methamphetamine use disorder. Psychopharmacology, 2017, Volume: 234, Issue:13 Topics: Anxiety; Behavior, Addictive; Conditioning, Psychological; Craving; Cues; Data Collection; Double-Blind Method; Emotions; Humans; Methamphetamine; Naltrexone; Time Factors	2017
Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model. Brain, behavior, and immunity, 2018, Volume: 67 Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Proliferation; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Interferon-alpha; Male; Naltrexone; Narcotic Antagonists; Neurons; Rats, Wistar; Receptors, Opioid	2018
Administration of a delta opioid receptor agonist KNT-127 to the basolateral amygdala has robust anxiolytic-like effects in rats. Psychopharmacology, 2018, Volume: 235, Issue:10 Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Basolateral Nuclear Complex; Fear; Learning; Male; Morphinans; Muscimol; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta	2018
A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice. Journal of pharmacological sciences, 2018, Volume: 138, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Anti-Anxiety Agents; Anxiety; Aspartic Acid; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Microinjections; Morphinans; Naltrexone; Prefrontal Cortex; Receptors, Opioid, delta	2018
Protracted withdrawal from ethanol and enhanced responsiveness stress: regulation via the dynorphin/kappa opioid receptor system. Alcohol (Fayetteville, N.Y.), 2013, Volume: 47, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcoholism; Analgesics, Non-Narcotic; Animals; Anxiety; Dose-Response Relationship, Drug; Dynorphins; Ethanol; Male; Maze Learning; Motor Activity; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, kappa; Stress, Psychological; Substance Withdrawal Syndrome	2013
Behavioral and neurochemical characterization of kratom (Mitragyna speciosa) extract. Psychopharmacology, 2014, Volume: 231, Issue:1 Topics: Administration, Oral; Animals; Anxiety; Behavior, Animal; Blotting, Western; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; HEK293 Cells; Hot Temperature; Humans; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Mice, Knockout; Mitragyna; Naltrexone; Narcotic Antagonists; Pain Threshold; Plant Extracts; Receptors, Dopamine D1; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2014
Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Dec-04, Volume: 33, Issue:49 Topics: Animals; Anxiety; Catheterization; Conditioning, Operant; Enkephalins; Heroin Dependence; Immunohistochemistry; Male; Motivation; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reinforcement Schedule; Self Administration; Substance Withdrawal Syndrome	2013
DOR(2)-selective but not DOR(1)-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127. Neuropharmacology, 2014, Volume: 79 Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzylidene Compounds; Exploratory Behavior; Formaldehyde; Male; Maze Learning; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Nociception; Rats; Rats, Wistar; Receptors, Opioid, delta	2014
Enkephalin analog, cyclo[N(ε),N(β)-carbonyl-D-Lys(2),Dap(5)] enkephalinamide (cUENK6), inhibits the ethanol withdrawal-induced anxiety-like behavior in rats. Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:3 Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Central Nervous System Depressants; Enkephalin, Leucine; Enkephalins; Ethanol; Morphine; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome	2015
Prefrontal Cortical Kappa Opioid Receptors Attenuate Responses to Amygdala Inputs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:13 Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Anxiety; Basolateral Nuclear Complex; Benzeneacetamides; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Mice, Inbred C57BL; Microelectrodes; Naltrexone; Narcotic Antagonists; Neural Pathways; Optogenetics; Prefrontal Cortex; Pyrrolidines; Random Allocation; Rats, Long-Evans; Receptors, Opioid, kappa	2015
Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist. Biological psychiatry, 2016, 06-01, Volume: 79, Issue:11 Topics: Amygdala; Animals; Anxiety; Corpus Striatum; Dendrites; Dopamine; Female; Hippocampus; Male; Mice, Inbred C57BL; Mice, Knockout; Movement Disorders; Naltrexone; Narcotic Antagonists; Receptors, G-Protein-Coupled; Receptors, Opioid, delta; Receptors, Opioid, mu; Serotonin; Spatial Learning	2016
Biphalin protects against cognitive deficits in a mouse model of mild traumatic brain injury (mTBI). Neuropharmacology, 2016, Volume: 101 Topics: Analgesics; Analysis of Variance; Animals; Anxiety; Brain Injuries; Cognition Disorders; Disease Models, Animal; Enkephalins; Exploratory Behavior; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Recognition, Psychology; Silver Staining	2016
Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests. Neuroscience letters, 2016, Feb-26, Volume: 615 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dynorphins; Feeding Behavior; Male; Mice; Motor Activity; Naltrexone; Peptide Fragments; Proteins; Receptors, Opioid, kappa	2016
The anxiolytic- and antidepressant-like effects of ATPM-ET, a novel κ agonist and μ partial agonist, in mice. Psychopharmacology, 2016, Volume: 233, Issue:12 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Avoidance Learning; Emotions; Exploratory Behavior; Hindlimb Suspension; Locomotion; Mice; Morphinans; Naltrexone; Receptors, Opioid, kappa; Receptors, Opioid, mu	2016
Endogenous opioids regulate glucocorticoid-dependent stress-coping strategies in mice. Neuroscience, 2016, 08-25, Volume: 330 Topics: Adaptation, Psychological; Amygdala; Animals; Anxiety; Conditioning, Psychological; Depression; Dexamethasone; Fear; Freezing Reaction, Cataleptic; Glucocorticoids; Male; Mice, Inbred Strains; Mifepristone; Motor Activity; Naltrexone; Neurotransmitter Agents; Opioid Peptides; Receptors, Glucocorticoid; Receptors, Opioid; Species Specificity; Stress, Psychological	2016
Effect of combined opioid receptor and α Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:6 Topics: Adolescent; Adrenergic alpha-2 Receptor Antagonists; Adult; Analgesics, Opioid; Anxiety; Blinking; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pain; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Reflex, Startle; Yohimbine; Young Adult	2017
Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amygdala; Animals; Anxiety; Brain Stem; Corticosterone; Corticotropin-Releasing Hormone; Dynorphins; Enkephalins; Exploratory Behavior; Female; Guanidines; Hypothalamus; Male; Maze Learning; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphinans; Naltrexone; Neuropeptide Y; Neuropeptides; Protein Precursors; Raphe Nuclei; Receptors, Opioid, kappa; Stress, Psychological	2009
Kappa-opioid system regulates the long-lasting behavioral adaptations induced by early-life exposure to methylphenidate. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:5 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Food Preferences; Male; Methylphenidate; Motor Activity; Naltrexone; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stress, Psychological	2009
Evidence for the involvement of the opioid system in the antidepressant-like effect of folic acid in the mouse forced swimming test. Behavioural brain research, 2009, Jun-08, Volume: 200, Issue:1 Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; Exploratory Behavior; Folic Acid; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Swimming	2009
Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:1 Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzamides; Diazepam; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Piperazines; Quinolines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, delta; Substance Withdrawal Syndrome	2010
A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors. Psychopharmacology, 2010, Volume: 212, Issue:4 Topics: Amygdala; Analgesics, Opioid; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fear; Male; Microinjections; Motor Activity; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Swimming; Time Factors	2010
Dorsal hippocampal opioidergic system modulates anxiety-like behaviors in adult male Wistar rats. Psychiatry and clinical neurosciences, 2010, Volume: 64, Issue:6 Topics: Analgesics, Opioid; Animals; Anxiety; CA1 Region, Hippocampal; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Male; Maze Learning; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu	2010
Dorsal hippocampal N-methyl-D-aspartate glutamatergic and δ-opioidergic systems modulate anxiety behaviors in rats in a noninteractive manner. The Kaohsiung journal of medical sciences, 2011, Volume: 27, Issue:11 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; CA1 Region, Hippocampal; Enkephalin, D-Penicillamine (2,5)-; Male; Maze Learning; Motor Activity; Naltrexone; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta	2011
κ opioid regulation of anxiety-like behavior during acute ethanol withdrawal. Pharmacology, biochemistry, and behavior, 2012, Volume: 102, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcoholism; Animals; Anxiety; Behavior, Animal; Ethanol; Male; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, kappa; Substance Withdrawal Syndrome	2012
Anxiolytic effects of ethanol are partially related to a reduced expression of adenylyl cyclase 5 but not to μ-opioid receptor activation in rat nucleus accumbens. Behavioural brain research, 2012, Dec-01, Volume: 235, Issue:2 Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Ethanol; Exploratory Behavior; Gene Expression Regulation, Enzymologic; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, mu; RNA, Messenger; Time Factors	2012
In vivo and in vitro characterization of naltrindole-derived ligands at the κ-opioid receptor. Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:2 Topics: Analgesics; Animals; Anxiety; Behavior, Animal; Depression; Guinea Pigs; Ligands; Male; Mice; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu	2013
Effects of a post-shock injection of the kappa opioid receptor antagonist norbinaltorphimine (norBNI) on fear and anxiety in rats. PloS one, 2012, Volume: 7, Issue:11 Topics: Animals; Anxiety; Behavior, Animal; Fear; Injections, Subcutaneous; Male; Naltrexone; Rats; Receptors, Opioid, kappa	2012
Involvement of the opioid system in the anxiolytic-like effects induced by Delta(9)-tetrahydrocannabinol. Psychopharmacology, 2002, Volume: 163, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Darkness; Dronabinol; Endorphins; Light; Male; Mice; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rimonabant	2002
[Anxiolytic effect of the dehydroepiandrosterone sulfate: mu-opioid mechanism]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:5 Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Competitive Behavior; Dehydroepiandrosterone Sulfate; Dominance-Subordination; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Social Dominance; Stress, Psychological	2003
The kappa-opioid receptor is involved in the stimulating effect of nicotine on adrenocortical activity but not in nicotine induced anxiety. Behavioural brain research, 2005, Sep-08, Volume: 163, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Corticosterone; Drug Interactions; Endocrine System; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Opioid, kappa	2005
Role of delta-opioid receptor subtypes in anxiety-related behaviors in the elevated plus-maze in rats. Psychopharmacology, 2005, Volume: 182, Issue:3 Topics: Animals; Anxiety; Benzamides; Benzylidene Compounds; Blood Specimen Collection; Corticosterone; Male; Maze Learning; Naltrexone; Piperazines; Rats; Rats, Inbred Lew; Receptors, Opioid, delta	2005
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors. Neuroscience, 2005, Volume: 135, Issue:2 Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; Emotions; Enkephalins; Enzyme Inhibitors; Exploratory Behavior; Freezing Reaction, Cataleptic; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Phenylalanine; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Swimming; Time Factors	2005
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:4 Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; Chronic Disease; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Piperazines; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatica; Somatostatin; Sulfur Isotopes; Time Factors; Tranquilizing Agents	2006
General anaesthesia is patient-friendly in opioid antagonist detoxification treatment. Addiction (Abingdon, England), 2005, Volume: 100, Issue:11 Topics: Anesthesia, General; Anxiety; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders	2005
Big dynorphin, a prodynorphin-derived peptide produces NMDA receptor-mediated effects on memory, anxiolytic-like and locomotor behavior in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:9 Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Hot Temperature; Male; Memory; Mice; Molecular Sequence Data; Motor Activity; Naltrexone; Pain Measurement; Protein Precursors; Reaction Time; Receptors, N-Methyl-D-Aspartate	2006
Development of a mouse model of ethanol addiction: naltrexone efficacy in reducing consumption but not craving. Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:9 Topics: Alcoholism; Animals; Anxiety; Disease Models, Animal; Individuality; Male; Mice; Motor Activity; Naltrexone; Narcotic Antagonists; Reproducibility of Results; Self Administration	2006
Delta opioid receptor ligands modulate anxiety-like behaviors in the rat. British journal of pharmacology, 2006, Volume: 147, Issue:8 Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Dose-Response Relationship, Drug; Male; Naltrexone; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	2006
Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:3 Topics: Adiposity; Animals; Anxiety; Behavior, Animal; Body Weight; Eating; Feeding Behavior; Female; Food; Food Preferences; Ghrelin; Growth Hormone; Leptin; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Wistar	2008
Negative affect, pain and sex: the role of endogenous opioids. Pain, 2007, Volume: 132 Suppl 1 Topics: Adolescent; Adult; Affect; Anger; Anxiety; Central Nervous System; Cold Temperature; Depression; Double-Blind Method; Electroshock; Female; Humans; Male; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Sex Characteristics; Stress, Psychological	2007
Neonatally administered naltrexone affects several behavioral responses in adult rats of both genders. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2 Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Emotions; Exploratory Behavior; Female; Habituation, Psychophysiologic; Male; Motor Activity; Naltrexone; Rats; Rats, Wistar; Sex Characteristics	1995
Factors that modulate inescapable shock-induced reductions in daily activity in the rat. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: Animals; Anxiety; Brain Chemistry; Carbolines; Electroshock; Helplessness, Learned; Male; Motor Activity; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stress, Psychological	1993
The role of subtypes of the opioid receptor in the anxiolytic action of chlordiazepoxide. Neuropharmacology, 1998, Volume: 37, Issue:2 Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Male; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid	1998
Acamprosate, but not naltrexone, inhibits conditioned abstinence behaviour associated with repeated ethanol administration and exposure to a plus-maze. Psychopharmacology, 2000, Volume: 147, Issue:4 Topics: Acamprosate; Alcohol Deterrents; Animals; Anxiety; Central Nervous System Depressants; Ethanol; Exploratory Behavior; Male; Mice; Naltrexone; Substance Withdrawal Syndrome; Taurine	2000
Changes in analgesia-producing mechanism of repeated cold stress loading in mice. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Anxiety; Cold Temperature; Diazepam; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pain Threshold; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Physiological	2000
Concurrent modulation of anxiety and memory. Behavioural brain research, 2000, Volume: 109, Issue:2 Topics: Animals; Anxiety; Behavior, Animal; Limbic System; Male; Maze Learning; Memory; Mice; Mice, Inbred Strains; Microinjections; Naltrexone; Narcotic Antagonists; Prefrontal Cortex; Random Allocation; Receptors, Opioid, kappa	2000
Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nature genetics, 2000, Volume: 25, Issue:2 Topics: Animals; Anxiety; Binding Sites; Darkness; Depression; Electroshock; Female; Gene Deletion; Light; Male; Mice; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Phenotype; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Characteristics; Swimming	2000
[Regulation of the central opioidergic nervous system on the emotional state of anxiety and its possible mechanisms]. Sheng li ke xue jin zhan [Progress in physiology], 1997, Volume: 28, Issue:1 Topics: Animals; Anxiety; Brain; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Serotonin; Substance Withdrawal Syndrome	1997
Opioid delta agonists and endogenous enkephalins induce different emotional reactivity than mu agonists after injection in the rat ventral tegmental area. Psychopharmacology, 1991, Volume: 103, Issue:4 Topics: Animals; Anxiety; Emotions; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Exploratory Behavior; Indoles; Injections; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali	1991
Antinociceptive effects of elevated plus-maze exposure: influence of opiate receptor manipulations. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred DBA; Morphine; Naltrexone; Pain; Pain Measurement; Receptors, Opioid	1990
The role of drugs in the treatment of opioid addicts. The Medical journal of Australia, 1986, Oct-20, Volume: 145, Issue:8 Topics: Alcoholism; Anxiety; Clonidine; Dextropropoxyphene; Heroin; Humans; Inactivation, Metabolic; Kinetics; Methadone; Mood Disorders; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders	1986
Potentiation of the propunishment, but not the convulsant action of the beta-carboline DMCM by naltrexone. Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3 Topics: Animals; Anxiety; Carbolines; Drug Synergism; Female; Male; Mice; Motor Activity; Naltrexone; Punishment; Receptors, GABA-A; Receptors, Opioid; Seizures	1986