naltrexone and Alzheimer Disease

naltrexone has been researched along with Alzheimer Disease in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, L; Pei, G; Teng, L; Wang, F; Zhao, J1
Read, SL1
Shi, C; Wang, S; Xie, X; Xue, G; Zhang, L; Zhang, R1
Andreason, PJ; Carson, RE; Cohen, RM; Doudet, DJ; Sunderland, T1
Carson, RE; Cohen, RM; Sunderland, T1
Damasio, AR; Eslinger, PJ; Hyman, BT1
Bagne, CA; Deptula, D; Galloway, MP; Pomara, N; Rhiew, HB; Stanley, M; Tamminga, CA; Tanimoto, K; Verebey, K1
Adler, J; Corwin, J; Jordan, B; Resnick, R; Rotrosen, JP; Serby, M1
Weiss, BL1
Tennant, FS1
Hartman, M; Knopman, DS1
Gershon, S; Pomara, N; Rhiew, HB; Roberts, R; Stanley, M1

Trials

5 trial(s) available for naltrexone and Alzheimer Disease

ArticleYear
Effect of naltrexone on senile dementia of the Alzheimer type.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:11

    Topics: Administration, Oral; Aged; Alzheimer Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naltrexone; Neuropsychological Tests; Receptors, Opioid

1985
Loss of the cortisol response to naltrexone in Alzheimer's disease.
    Biological psychiatry, 1988, Apr-01, Volume: 23, Issue:7

    Topics: Aged; Alzheimer Disease; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Methoxyhydroxyphenylglycol; Naltrexone; Prolactin

1988
Naltrexone and Alzheimer's disease.
    Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:3-5

    Topics: Alzheimer Disease; Clinical Trials as Topic; Humans; Naltrexone

1986
Failure of nalmefene and estrogen to improve memory in Alzheimer's disease.
    The American journal of psychiatry, 1987, Volume: 144, Issue:3

    Topics: Alzheimer Disease; Clinical Trials as Topic; Estradiol; Female; Humans; Memory; Memory Disorders; Naltrexone

1987
Multiple, single-dose naltrexone administrations fail to effect overall cognitive functioning and plasma cortisol in individuals with probable Alzheimer's disease.
    Neurobiology of aging, 1985,Fall, Volume: 6, Issue:3

    Topics: Aged; Alzheimer Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Middle Aged; Naltrexone

1985

Other Studies

7 other study(ies) available for naltrexone and Alzheimer Disease

ArticleYear
A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
    Cell research, 2010, Volume: 20, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Cells, Cultured; Dipeptides; Enkephalin, Leucine-2-Alanine; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiprotein Complexes; Naltrexone; Narcotic Antagonists; Protein Transport; Receptors, G-Protein-Coupled; Receptors, Opioid, delta; Substrate Specificity; Transport Vesicles

2010
Naltrexone effects in patients with dementia.
    The American journal of psychiatry, 2010, Volume: 167, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Alcoholism; Alzheimer Disease; Behavior, Addictive; Comorbidity; Female; Humans; Male; Naltrexone; Treatment Outcome

2010
Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer's disease mouse model.
    Journal of Alzheimer's disease : JAD, 2012, Volume: 31, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Female; Humans; Indans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naltrexone; Pattern Recognition, Visual; Piperidines; Presenilin-1; Random Allocation

2012
Opiate receptor avidity and cerebral blood flow in Alzheimer's disease.
    Journal of the neurological sciences, 1997, May-29, Volume: 148, Issue:2

    Topics: Aged; Alzheimer Disease; Brain Chemistry; Cerebrovascular Circulation; Female; Fluorine Radioisotopes; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Nerve Degeneration; Receptors, Opioid; Tomography, Emission-Computed

1997
Opiate receptor avidity in the thalamus is sexually dimorphic in the elderly.
    Synapse (New York, N.Y.), 2000, Volume: 38, Issue:2

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Female; Humans; Male; Middle Aged; Naltrexone; Receptors, Opioid; Regression Analysis; Sex Factors; Thalamus; Tomography, Emission-Computed

2000
Preliminary observations on naltrexone for treatment of Alzheimer's type dementia.
    Journal of the American Geriatrics Society, 1987, Volume: 35, Issue:4

    Topics: Aged; Alzheimer Disease; Dementia; Humans; Middle Aged; Naltrexone

1987
Cognitive effects of high-dose naltrexone in patients with probable Alzheimer's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:11

    Topics: Aged; Alzheimer Disease; Female; Humans; Male; Naltrexone

1986