Compounds > naltrexone

naltrexone and Acute Liver Injury, Drug-Induced

naltrexone has been researched along with Acute Liver Injury, Drug-Induced in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.26)	18.7374
1990's	2 (10.53)	18.2507
2000's	3 (15.79)	29.6817
2010's	12 (63.16)	24.3611
2020's	1 (5.26)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ahmadian, S; Dehpour, AR; Ebrahim-Habibi, A; Kashani-Amin, E; Malek, MR; Shafizadeh, M	1
Azar, MR; Cashman, JR	1
Dehpou, AR; Dehpour, AR; Hassanzadeh, G; Moslehi, A; Nabavizadeh, F; Nahrevanian, H; Sohanaki, H; Tavanga, SM; Zekri, A	1
Cheng, PY; Peng, YJ; Wang, CC; Wei, HP; Wu, ES; Yen, MH	1
Garbutt, JC	1
Clemens, MG; Day, SA; Lakner, AM; Moore, CC; Schrum, LW; Wu, ES; Yen, MH	1
Bryant, K; Fiellin, DA; Goulet, JL; Justice, AC; McGinnis, KA; Sullivan, LE; Tate, JP; Tetrault, JM	1
Henderson, RD; McCombe, PA	1
Hong, JS; Ko, HC; Lu, RB; Tang, FI; Yen, MH	1
Kim, A; Kornetsky, C; Sax, DS	1
Hetrick, WP; Krutzik, MN; Martinazzi, VP; Rusu, L; Sandman, CA; Taylor, DV	1
Mitchell, JE	1

Reviews

2 review(s) available for naltrexone and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Efficacy and tolerability of naltrexone in the management of alcohol dependence. Current pharmaceutical design, 2010, Volume: 16, Issue:19 Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Naltrexone; Narcotic Antagonists; Nausea	2010

Other Studies

17 other study(ies) available for naltrexone and Acute Liver Injury, Drug-Induced

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Investigating the role of endogenous opioid system in chloroquine-induced phospholipidosis in rat liver by morphological, biochemical and molecular modelling studies. Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:9 Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroquine; Disease Models, Animal; Fatty Liver; Glycine; Hippurates; Liver; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Naltrexone; Narcotic Antagonists; Opioid Peptides; Phospholipids; Rats; Receptors, Opioid, mu; Signal Transduction	2020
Potent inhibition of alcohol self-administration in alcohol-preferring rats by a κ-opioid receptor antagonist. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:1 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Conditioning, Operant; Ethanol; Male; Morphinans; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Self Administration; Thioamides	2014
Naltrexone attenuates endoplasmic reticulum stress induced hepatic injury in mice. Acta physiologica Hungarica, 2014, Volume: 101, Issue:3 Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Chemical and Drug Induced Liver Injury; Cholesterol; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Fatty Liver; Liver; Liver Circulation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Non-alcoholic Fatty Liver Disease; Proto-Oncogene Proteins c-bcl-2; Triglycerides; Tumor Necrosis Factor-alpha; Tunicamycin	2014
Naltrexone protects against lipopolysaccharide/D-galactosamine-induced hepatitis in mice. Journal of pharmacological sciences, 2008, Volume: 108, Issue:3 Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Neutrophils; Nitrates; Nitrites; Superoxides; Time Factors; Tumor Necrosis Factor-alpha	2008
Opioid-like compound exerts anti-fibrotic activity via decreased hepatic stellate cell activation and inflammation. Biochemical pharmacology, 2011, Apr-15, Volume: 81, Issue:8 Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen; Disease Models, Animal; Hepatic Stellate Cells; Immunoblotting; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Morphinans; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction	2011
Hepatic safety and antiretroviral effectiveness in HIV-infected patients receiving naltrexone. Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:2 Topics: Adult; Aged; Alanine Transaminase; Alcoholism; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; CD4 Lymphocyte Count; Chemical and Drug Induced Liver Injury; Cohort Studies; Databases, Factual; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Liver; Liver Function Tests; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; RNA, Viral; Veterans	2012
Riluzole: a glimmer of hope in the treatment of motor neurone disease. The Medical journal of Australia, 2005, Aug-01, Volume: 183, Issue:3 Topics: Chemical and Drug Induced Liver Injury; Drug Interactions; Humans; Male; Middle Aged; Motor Neuron Disease; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Riluzole	2005
Study of hepatotoxicity of naltrexone in the treatment of alcoholism. Alcohol (Fayetteville, N.Y.), 2006, Volume: 38, Issue:2 Topics: Adolescent; Adult; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Time Factors	2006
Lack of hepatotoxicity with naltrexone treatment. Journal of clinical pharmacology, 1994, Volume: 34, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Humans; Huntington Disease; Liver Function Tests; Middle Aged; Movement Disorders; Naltrexone	1994
Naltrexone has no hepatotoxic effects in a self-injurious patient with chronic hepatitis. Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:6 Topics: Adult; Chemical and Drug Induced Liver Injury; Hepatitis, Viral, Human; Humans; Liver Function Tests; Male; Naltrexone; Self-Injurious Behavior	1993
Naltrexone and hepatotoxicity. Lancet (London, England), 1986, May-24, Volume: 1, Issue:8491 Topics: Chemical and Drug Induced Liver Injury; Humans; Hyperphagia; Naltrexone	1986