naloxone has been researched along with Heart-Valve-Diseases* in 3 studies
3 other study(ies) available for naloxone and Heart-Valve-Diseases
| Article | Year |
|---|---|
Effects of mu-, delta- and kappa-opioid antagonists in atrial preparations from nonfailing and failing human hearts.
1. We examined the effects of naloxone (preferentially mu-antagonist), naltrindole (selective delta-antagonist) or nor-binaltorphimine (nor-BNI, selective kappa-antagonist) on auricular myocardium tissue from nonfailing and failing human hearts. 2. The opioid antagonists used in this study induced inhibitory effects in auricular strips from failing and nonfailing human hearts. In addition, the maximal effect, the IC50, and the slope of concentration-response curves obtained with mu-, delta-, and kappa-opioid antagonists were similar in failing and nonfailing human heart tissues. 3. The kappa-antagonist was more effective than naltrindole or naloxone. Moreover, the IC50 for nor-BNI (0.25 +/- 0.01 x 10(-5) M) was lower than the IC50 for naloxone (26.5 +/- 5.0 x 10(-5) M) and naltrindole (13.8 +/- 2.0 x 10(-5) M). Similar results were obtained in auricular strips from failing human hearts. 4. Our results demonstrate that the failing heart does not modify the inhibitory cardiac effects obtained with selective opioid antagonists. Topics: Adult; Aged; Depression, Chemical; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Heart Valve Diseases; Humans; In Vitro Techniques; Male; Middle Aged; Mitral Valve; Myocardial Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
High dose fentanyl-oxygen anesthesia for intracranial mycotic aneurysm surgery: a clinical report.
The resection of a mycotic aneurysm in a patient with concurrent cardiac valvular disease was carried out successfully using high dose fentanyl-oxygen anesthesia followed by immediate postoperative naloxone reversal. The technique and benefits of this type of anesthesia in neurosurgical procedures are discussed. Topics: Adult; Anesthesia; Aneurysm, Infected; Female; Fentanyl; Heart Valve Diseases; Humans; Intracranial Aneurysm; Naloxone; Oxygen; Postoperative Care | 1983 |
High-performance liquid chromatographic analysis of plasma levels of nalbuphine in cardiac surgical patients.
Topics: Adult; Aged; Anesthesia; Chromatography, High Pressure Liquid; Electrochemistry; Half-Life; Heart Valve Diseases; Humans; Middle Aged; Morphinans; Nalbuphine; Naloxone; Reference Standards | 1982 |