naloxone has been researched along with Cadaver* in 3 studies
1 trial(s) available for naloxone and Cadaver
Article | Year |
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Opiate receptor blockade improves function and survival of high-risk renal allografts.
Topics: Adult; Cadaver; Graft Survival; Hemodynamics; Humans; Immunosuppressive Agents; Kidney Transplantation; Naloxone; Narcotic Antagonists; Renal Artery; Tissue Donors; Transplantation, Homologous | 1993 |
2 other study(ies) available for naloxone and Cadaver
Article | Year |
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Respiratory arrest after cadaveric renal transplant.
Topics: Adult; Analgesics, Opioid; Cadaver; Fentanyl; Humans; Kidney Transplantation; Male; Naloxone; Narcotic Antagonists; Respiratory Insufficiency | 2009 |
Tritiated-naloxone binding to brainstem opioid receptors in the sudden infant death syndrome.
The sudden infant death syndrome (SIDS) is defined as the sudden death of an infant under 1 year of age that remains unexplained after a thorough case investigation, including a complete autopsy. We hypothesized that SIDS is associated with altered 3H - naloxone binding to opioid receptors in brainstem nuclei related to respiratory and autonomic control. We analyzed 3H - naloxone binding in 21 regions in SIDS and control brainstems using quantitative tissue receptor autoradiography. Three groups were analyzed: SIDS (n = 45); acute controls (n = 14); and a chronic group with oxygenation disorders (n = 15). Opioid binding was heavily concentrated in the caudal nucleus of the solitary tract, nucleus parabrachialis medialis, spinal trigeminal nucleus, inferior olive, and interpeduncular nucleus in all cases analyzed (n = 74). The arcuate nucleus on the ventral medullary surface contained negligible binding in all cases (n = 74), and therefore binding was not measurable at this site. We found no significant differences among the three groups in the age-adjusted mean 3H - naloxone binding in 21 brainstem sites analyzed. The only differences we have found to date between SIDS and acute controls are decreases in 3H - quinuclidinyl benzilate binding to muscarinic cholinergic receptors and in 3H - kainate binding to kainate receptors in the arcuate nucleus in alternate sections of this same data set. The present study suggests that there is not a defect in opioid receptor binding in cardiorespiratory nuclei in SIDS brainstems. Topics: Autoradiography; Brain Stem; Cadaver; Humans; Hypoxia; Infant; Infant, Newborn; Naloxone; Receptors, Opioid; Sudden Infant Death; Tissue Distribution; Tritium | 1998 |