nalmefene and Drug Withdrawal Symptoms

nalmefene has been researched along with Drug Withdrawal Symptoms in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's4 (20.00)18.2507
2000's3 (15.00)29.6817
2010's11 (55.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Kunzler, NM; Nelson, LS; Wightman, RS1
Gibaja, V; Gillet, P; Labroca, P; Lemarié, J; Martini, H; Paille, F; Petitpain, N; Yéléhé-Okouma, M1
Franchitto, N; Jullian, B; Pelissier, F; Rolland, B; Salles, J1
Carton, L; Gaboriau, L; Lescut, C; Rolland, B1
Astrup, A; Christensen, R; Johansen, KGV; Lund, H; Pagsberg, AK; Tarp, S1
Heinz, A; Müller, CA1
Donnerstag, N; Lüthi, A; Mehlig, A; Raetz Bravo, A; Schneider, T; Taegtmeyer, A1
Higuchi, S; Yumoto, Y1
Dahmke, H; Kullak-Ublick, GA; Kupferschmidt, H; Weiler, S1
Franchitto, N; Nubukpo, P; Pélissier, F; Rougé Bugat, ME1
Ali, R; Gowing, L; White, JM1
Bilsky, EJ; Giuvelis, D; Lowery, JJ; Osborn, MD; Skorput, AG1
Koob, GF; Walker, BM1
Bauman, M; Bullen, BA; Evans, WJ; Henley, K; McArthur, JW; Pehrson, J; Skrinar, GS; Turnbull, BA; Turner, A1
Chami, TN; Cheskin, LJ; Jaffe, JH; Johnson, RE1
Capodano, RJ; Gaeta, TJ; Spevack, TA1
Cullen, DJ; Dwyer, MJ; Gold, CG; Gonzales, S; Houtmeyers, D1
Brady, KT; Malcolm, R; Myrick, H1
Bilsky, EJ; Raehal, KM; Sadée, W; Wang, D1
Losowsky, MS; Thornton, JR1

Reviews

7 review(s) available for nalmefene and Drug Withdrawal Symptoms

ArticleYear
Opioid Withdrawal Precipitated by Long-Acting Antagonists.
    The Journal of emergency medicine, 2020, Volume: 58, Issue:2

    Topics: Drug Combinations; Emergency Service, Hospital; Humans; Morphine; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome

2020
Management of precipitated opiate withdrawal syndrome induced by nalmefene mistakenly prescribed in opiate-dependent patients: a review for clinicians.
    Expert opinion on drug metabolism & toxicology, 2017, Volume: 13, Issue:6

    Topics: Alcoholism; Analgesics, Opioid; Animals; Drug Interactions; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Risk Factors; Substance Withdrawal Syndrome

2017
Harms associated with taking nalmefene for substance use and impulse control disorders: A systematic review and meta-analysis of randomised controlled trials.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Disruptive, Impulse Control, and Conduct Disorders; Humans; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders

2017
[New treatment options for alcohol dependence].
    MMW Fortschritte der Medizin, 2013, May-02, Volume: 155, Issue:8

    Topics: Acamprosate; Alcoholism; Baclofen; Combined Modality Therapy; Ethanol; Fructose; Humans; Naltrexone; Psychotherapy; Secondary Prevention; Socioenvironmental Therapy; Substance Withdrawal Syndrome; Taurine; Topiramate

2013
[Pharmacological therapies for alcohol use disorder in Japan].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73, Issue:9

    Topics: Acamprosate; Alcohol-Related Disorders; Alcohols; Humans; Japan; Naltrexone; Substance Withdrawal Syndrome; Taurine

2015
Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal.
    The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1

    Topics: Anesthetics; Humans; Hypnotics and Sedatives; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome

2010
New developments in the pharmacotherapy of alcohol dependence.
    The American journal on addictions, 2001, Volume: 10, Issue:s1

    Topics: Acamprosate; Adjuvants, Anesthesia; Alcohol Deterrents; Alcoholism; Anticonvulsants; Buspirone; Carbamazepine; Drug Therapy; Ethanol; Humans; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Ritanserin; Serotonin Agents; Sodium Oxybate; Substance Withdrawal Syndrome; Taurine; Valproic Acid; Vigabatrin

2001

Trials

4 trial(s) available for nalmefene and Drug Withdrawal Symptoms

ArticleYear
Nalmefene enhances LH secretion in a proportion of oligo-amenorrheic athletes.
    Acta endocrinologica, 1993, Volume: 128, Issue:4

    Topics: Adult; Amenorrhea; Analysis of Variance; Androstenedione; Dehydroepiandrosterone; Estradiol; Female; Humans; Luteinizing Hormone; Menstruation; Naltrexone; Narcotic Antagonists; Oligomenorrhea; Physical Education and Training; Pituitary Gland; Progesterone; Sports; Substance Withdrawal Syndrome; Thyrotropin; Thyroxine; Time Factors; Vagina

1993
Assessment of nalmefene glucuronide as a selective gut opioid antagonist.
    Drug and alcohol dependence, 1995, Volume: 39, Issue:2

    Topics: Adult; Arousal; Autonomic Nervous System; Constipation; Dose-Response Relationship, Drug; Gastrointestinal Motility; Humans; Male; Methadone; Naltrexone; Narcotic Antagonists; Neurologic Examination; Opioid-Related Disorders; Substance Withdrawal Syndrome

1995
Rapid opioid detoxification during general anesthesia: a review of 20 patients.
    Anesthesiology, 1999, Volume: 91, Issue:6

    Topics: Adult; Anesthesia, General; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome

1999
Opioid peptides and primary biliary cirrhosis.
    BMJ (Clinical research ed.), 1988, Dec-10, Volume: 297, Issue:6662

    Topics: Adult; Aged; Bilirubin; Fatigue; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pruritus; Substance Withdrawal Syndrome

1988

Other Studies

9 other study(ies) available for nalmefene and Drug Withdrawal Symptoms

ArticleYear
Opioid substitution therapy or hidden opioids are a minefield for nalmefene: an atypical case series of 11 patients in Lorraine.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:5

    Topics: Adult; Aged; Alcoholism; Analgesics, Opioid; Female; France; Gastrointestinal Diseases; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Pancreatitis; Retrospective Studies; Substance Withdrawal Syndrome

2017
Naltrexone- or Nalmefene-Related Buprenorphine Withdrawal: Treat It With… More Buprenorphine.
    Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:5

    Topics: Alcoholism; Antisocial Personality Disorder; Buprenorphine; Heroin Dependence; Humans; Male; Medication Errors; Middle Aged; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome

2017
Severe opioid withdrawal syndrome after a single dose of nalmefene.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Adult; Alcoholism; Analgesics, Opioid; Codeine; Contraindications; Drug Interactions; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2015
[Nalmefene and Opioid Withdrawal Syndrome: Analysis of the Global Pharmacovigilance Database for Adverse Drug Reactions].
    Praxis, 2015, Oct-14, Volume: 104, Issue:21

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Alcoholism; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Pharmacovigilance; Substance Withdrawal Syndrome

2015
Nalmefene Mistakenly Prescribed to Reduce Alcohol Consumption in Patients Under Buprenorphine Substitution Therapy Resulting in Acute Opioid Withdrawal: Management in an Emergency Setting.
    Journal of clinical psychopharmacology, 2016, Volume: 36, Issue:1

    Topics: Adult; Alcohol Drinking; Analgesics, Opioid; Buprenorphine; Drug Interactions; Female; Humans; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2016
In vivo characterization of the opioid antagonist nalmefene in mice.
    Life sciences, 2010, Apr-10, Volume: 86, Issue:15-16

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Time Factors

2010
Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:3

    Topics: Administration, Inhalation; Alcoholism; Animals; Central Nervous System Depressants; Conditioning, Operant; Data Interpretation, Statistical; Dynorphins; Ethanol; Injections, Intraventricular; Male; Motivation; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Substance Withdrawal Syndrome

2008
Potential danger of nalmefene use in the emergency department.
    Annals of emergency medicine, 1997, Volume: 29, Issue:1

    Topics: Emergency Service, Hospital; Heroin; Humans; Naltrexone; Narcotic Antagonists; Patient Discharge; Substance Withdrawal Syndrome

1997
Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence.
    Journal of neurochemistry, 2001, Volume: 77, Issue:6

    Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cell Line; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kidney; Magnesium; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Receptors, Opioid, mu; Signal Transduction; Substance Withdrawal Syndrome; Sulfur Radioisotopes; Transfection; Tritium

2001