nalmefene and Disease Models, Animal

nalmefene has been researched along with Disease Models, Animal in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Kang, P; Wang, HQ; Yang, J; Yang, P; Zhang, NL; Zhao, T1
Browne, CA; Lucki, I; Smith, T1
Bidlack, JM; Callaghan, CK; Dean, RL; Deaver, DR; Knapp, BI; O'Mara, SM; Rouine, J1
Bont, L; Gharagozlou, MJ; Golara, M; Jamali, A; Mahmoodi, M; Minaei, B; Mirzaei, H; Mokhtari-Azad, T; Ramezani, A; Salimi, V; Shahabi, S; Shokri, F; Tahamtan, A1
Diouf, M; González-Marín, MC; Jeanblanc, J; Lebourgeois, S; Naassila, M1
Hackett, D; Heal, DJ; Hutson, PH; Murray, F; Vickers, SP1
Dudek, M; Herr, DR; Hytönen, HR; Hyytiä, P; Korpi, ER; Linden, AM; Paasikoski, N; Vashchinkina, E1
Bilsky, EJ; Giuvelis, D; Lowery, JJ; Osborn, MD; Skorput, AG1
Clemens, MG; Day, SA; Lakner, AM; Moore, CC; Schrum, LW; Wu, ES; Yen, MH1
June, HL1
Faden, AI; McIntosh, TK; Rhomhanyi, R; Vink, R1

Other Studies

12 other study(ies) available for nalmefene and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Effects of nalmefene hydrochloride on TLR4 signaling pathway in rats with lung ischemia-reperfusion injury.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:1

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Thoracotomy; Toll-Like Receptor 4

2020
Behavioral effects of the kappa opioid receptor partial agonist nalmefene in tests relevant to depression.
    European journal of pharmacology, 2020, Apr-05, Volume: 872

    Topics: Animals; Behavior Observation Techniques; Behavior, Animal; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Repositioning; Female; Humans; Male; Mice; Mice, Knockout; Naltrexone; Nucleus Accumbens; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Factors

2020
Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model.
    Brain, behavior, and immunity, 2018, Volume: 67

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Proliferation; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Interferon-alpha; Male; Naltrexone; Narcotic Antagonists; Neurons; Rats, Wistar; Receptors, Opioid

2018
Blocking of opioid receptors in experimental formaline-inactivated respiratory syncytial virus (FI-RSV) immunopathogenesis: from beneficial to harmful impacts.
    Medical microbiology and immunology, 2018, Volume: 207, Issue:2

    Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Immunologic Factors; Lung; Mice, Inbred BALB C; Naltrexone; Narcotic Antagonists; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus Vaccines; T-Lymphocyte Subsets; Viral Load

2018
Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking.
    Neuropharmacology, 2018, 09-15, Volume: 140

    Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Hydroxybutyrates; Male; Motivation; Naltrexone; Rats; Self Administration

2018
Effects of lisdexamfetamine in a rat model of binge-eating.
    Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:12

    Topics: Animals; Baclofen; Behavior, Animal; Benzazepines; Benzodiazepines; Body Weight; Bulimia; Disease Models, Animal; Eating; Feeding Behavior; Female; Idazoxan; Lisdexamfetamine Dimesylate; Naltrexone; Olanzapine; Prazosin; Prodrugs; Raclopride; Rats; Rats, Wistar; Rolipram

2015
Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors.
    Addiction biology, 2017, Volume: 22, Issue:4

    Topics: Alcoholism; Animals; Brain; Disease Models, Animal; Ethanol; Female; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid

2017
In vivo characterization of the opioid antagonist nalmefene in mice.
    Life sciences, 2010, Apr-10, Volume: 86, Issue:15-16

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Time Factors

2010
Opioid-like compound exerts anti-fibrotic activity via decreased hepatic stellate cell activation and inflammation.
    Biochemical pharmacology, 2011, Apr-15, Volume: 81, Issue:8

    Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen; Disease Models, Animal; Hepatic Stellate Cells; Immunoblotting; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Morphinans; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2011
Preclinical models to evaluate potential pharmacotherapeutic agents in treating alcoholism and studying the neuropharmacological bases of ethanol-seeking behaviors in rats.
    Current protocols in neuroscience, 2002, Volume: Chapter 9

    Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Addictive; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Female; Male; Naltrexone; Rats; Reinforcement Schedule

2002
Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:11

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain Injuries; Disease Models, Animal; Energy Metabolism; Magnesium; Magnetic Resonance Spectroscopy; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains

1990