nalidixic acid has been researched along with Cystic Fibrosis in 4 studies
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Five hundred Haemophilus influenzae isolates were screened for an increased frequency of mutation to resistance to rifampicin, nalidixic acid and spectinomycin: of the 14 hypermutable isolates identified, 12 were isolated from cystic fibrosis (CF) sputum." | 3.72 | Hypermutable Haemophilus influenzae with mutations in mutS are found in cystic fibrosis sputum. ( Burns, JL; Smith, AL; Watson, ME, 2004) |
| "Pseudomonas Isolation Agar (selective agent, Irgasan, 25 mg/1) and Pseudomonas Selective Agar (selective agents, cetrimide 200mg/1 and nalidixic acid 15 mg/1) inhibited some strains of P aeruginosa from cystic fibrosis sputum but did not inhibit isolates from other sources." | 3.67 | Inhibition of Pseudomonas aeruginosa from cystic fibrosis by selective media. ( Fonseca, K; MacDougall, J; Pitt, TL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, WJ | 1 |
| Goeckeler-Fried, JL | 1 |
| Havasi, V | 1 |
| Chiang, A | 1 |
| Rowe, SM | 1 |
| Plyler, ZE | 1 |
| Hong, JS | 1 |
| Mazur, M | 1 |
| Piazza, GA | 1 |
| Keeton, AB | 1 |
| White, EL | 1 |
| Rasmussen, L | 1 |
| Weissman, AM | 1 |
| Denny, RA | 1 |
| Brodsky, JL | 1 |
| Sorscher, EJ | 1 |
| Watson, ME | 1 |
| Burns, JL | 1 |
| Smith, AL | 1 |
| Fonseca, K | 1 |
| MacDougall, J | 1 |
| Pitt, TL | 1 |
| Prince, A | 1 |
4 other studies available for nalidixic acid and Cystic Fibrosis
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regu | 2016 |
Hypermutable Haemophilus influenzae with mutations in mutS are found in cystic fibrosis sputum.
Topics: Adenosine Triphosphatases; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-La | 2004 |
Inhibition of Pseudomonas aeruginosa from cystic fibrosis by selective media.
Topics: Carbanilides; Cetrimonium; Cetrimonium Compounds; Culture Media; Cystic Fibrosis; Humans; Nalidixic | 1986 |
Antibiotic resistance of Pseudomonas species.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Lactams | 1986 |