nalbuphine and Asphyxia

nalbuphine has been researched along with Asphyxia* in 1 studies

Other Studies

1 other study(ies) available for nalbuphine and Asphyxia

Article	Year
[Post-asphyctic encephalopathy of the neonate following administration of nalbuphine during childbirth]. Nederlands tijdschrift voor geneeskunde, 1992, May-30, Volume: 136, Issue:22 After an intramuscular injection of nalbuphine during parturition a foetal bradycardia of 30-40 beats/minute developed, which normalised after an intravenous maternal injection of naloxone. Because the cardiotocography did not show variability after the event, a caesarean section was performed. Six months later the child still had a severe neurological disorder which was attributed to intrauterine asphyxia. Several authors published reports in which no relevant clinical problems were described after nalbuphine given during labour. Recently, however, four children have been described with bradycardia and respiratory depression after maternal intravenous and/or intramuscular injection of nalbuphine. Apparently, the use of nalbuphine during labour can cause foetal bradycardia, both after intravenous and after intramuscular administration. Great reserve is advised regarding use of nalbuphine for this indication. The antidote naloxone should be within reach. Topics: Adult; Asphyxia; Brain Diseases; Cardiotocography; Cesarean Section; Female; Fetal Diseases; Heart Rate, Fetal; Humans; Infant, Newborn; Nalbuphine; Pregnancy	1992

Article

Year

[Post-asphyctic encephalopathy of the neonate following administration of nalbuphine during childbirth].

Nederlands tijdschrift voor geneeskunde, 1992, May-30, Volume: 136, Issue:22

After an intramuscular injection of nalbuphine during parturition a foetal bradycardia of 30-40 beats/minute developed, which normalised after an intravenous maternal injection of naloxone. Because the cardiotocography did not show variability after the event, a caesarean section was performed. Six months later the child still had a severe neurological disorder which was attributed to intrauterine asphyxia. Several authors published reports in which no relevant clinical problems were described after nalbuphine given during labour. Recently, however, four children have been described with bradycardia and respiratory depression after maternal intravenous and/or intramuscular injection of nalbuphine. Apparently, the use of nalbuphine during labour can cause foetal bradycardia, both after intravenous and after intramuscular administration. Great reserve is advised regarding use of nalbuphine for this indication. The antidote naloxone should be within reach.

Topics: Adult; Asphyxia; Brain Diseases; Cardiotocography; Cesarean Section; Female; Fetal Diseases; Heart Rate, Fetal; Humans; Infant, Newborn; Nalbuphine; Pregnancy

1992