Page last updated: 2024-10-31

naftopidil and Urination Disorders

naftopidil has been researched along with Urination Disorders in 20 studies

Urination Disorders: Abnormalities in the process of URINE voiding, including bladder control, frequency of URINATION, as well as the volume and composition of URINE.

Research Excerpts

ExcerptRelevanceReference
"To examine the efficacy of dose increase therapy in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia who responded poorly to 50 mg/day of naftopidil."9.17α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy. ( Kakizaki, H; Numata, A; Osanai, H; Watanabe, M; Yamaguchi, S, 2013)
"We compared the efficacy, safety, and patient preferences for two α1-adrenoceptor (AR) antagonists with different affinity for AR subtypes, naftopidil (Naf) and silodosin (Silo), for the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia (male LUTS/BPH)."9.16[Comparison of naftopidil and silodosin in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, crossover study]. ( Asakura, T; Hashiba, T; Jinza, S; Masuda, M; Masuko, H, 2012)
"To investigate the incidence of ejaculatory disorders caused by naftopidil and tamsulosin in patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)."9.14Ejaculatory disorders caused by alpha-1 blockers for patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: comparison of naftopidil and tamsulosin in a randomized multicenter study. ( Furuya, R; Iwasawa, A; Masumori, N; Mori, M; Sonoda, T; Tsukamoto, T, 2009)
"We examined the tolerability of dosage methods of naftopidil in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH/male LUTS)."9.14A prospective, randomized, controlled, multicenter study of naftopidil for treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: 75 mg once daily in the evening compared to 25 mg thrice daily. ( Kazama, T; Kimura, H; Nozaki, T; Okumura, A; Tsuritani, S, 2010)
"To compare the efficacy of two alpha(1)-adrenoceptor antagonists, alpha(1A)-adrenoceptor-selective tamsulosin hydrochloride and alpha(1D)-adrenoceptor-selective naftopidil, in the treatment of lower urinary tract symptoms (LUTS) with benign prostatic hyperplasia (BPH)."9.12Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: a randomized crossover study. ( Deguchi, T; Ishihara, S; Masue, T; Miwa, K; Nishino, Y; Takahashi, Y, 2006)
"The present study investigated the efficacy, safety, and utility of starting an alpha(1d)-selective antagonist, naftopidil, at 75 or 25 mg/day in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)."9.12Comparison of 25 and 75 mg/day naftopidil for lower urinary tract symptoms associated with benign prostatic hyperplasia: a prospective, randomized controlled study. ( Kumon, H; Nasu, Y; Takamoto, H; Watanabe, T; Yokoyama, T, 2006)
"We studied the efficacy of naftopidil (50 mg/day) on nocturia associated with benign prostatic hyperplasia in 35 patients (62-80 years old)."9.10[Clinical effects of naftopidil on nocturia associated with benign prostatic hyperplasia]. ( Araki, I; Fukuzawa, S; Hashimura, T; Soeda, T; Sugino, Y; Takeuchi, H; Taki, Y, 2003)
"Naftopidil, a phenylpiperazine derivative, is a novel alpha 1-adrenoceptor antagonist and is new drug for the bladder outlet obstruction in patients with benign prostatic hyperplasia (BPH)."8.80[Pharmacological properties of naftopidil, a drug for treatment of the bladder outlet obstruction for patients with benign prostatic hyperplasia]. ( Ikegaki, I, 2000)
"We examined the effectiveness of naftopidil in 81 patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)."7.74[The effectiveness of naftopidil in patients with benign prostatic hyperplasia evaluated by QOL index]. ( Hamano, S; Murakami, S; Nakatsu, H; Naoi, M; Sekiyama, K; Suzuki, N; Tanaka, M, 2007)
"Naftopidil was administered to 67 patients with benign prostatic hyperplasia (BPH) for 12 months."7.72[Long-term efficacy of naftopidil for treatment of lower urinary tract symptoms with benign prostatic hyperplasia]. ( Akasaka, T; Fujishima, M; Funaki, H; Hirano, S; Iinuma, M; Kudou, T; Ohinata, M; Suzuki, A, 2003)
"Tamsulosin was more effective than naftopidil on intermittency, nocturia and quality of life scores."6.73Crossover comparison study on the therapeutic effects of tamsulosin hydrochloride and naftopidil in lower urinary tract symptoms associated with benign prostatic hyperplasia. ( Hosokawa, Y; Kishino, T; Momose, H; Ono, T; Oyama, N, 2007)
"Naftopidil was administered for three months to the patients with BPH who had nocturia with a urinary frequency of two or more times."5.32[Etiology of nocturia and clinical efficacy of naftopidil on nocturia in patients with benign prostatic hyperplasia--analysis of frequency volume charts]. ( Furuhata, A; Hirokawa, M; Hiromoto, Y; Ikeda, A; Kawasaki, C; Masuda, M; Nakayama, K; Satomi, Y; Shiramizu, M, 2004)
"To examine the efficacy of dose increase therapy in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia who responded poorly to 50 mg/day of naftopidil."5.17α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy. ( Kakizaki, H; Numata, A; Osanai, H; Watanabe, M; Yamaguchi, S, 2013)
"We compared the efficacy, safety, and patient preferences for two α1-adrenoceptor (AR) antagonists with different affinity for AR subtypes, naftopidil (Naf) and silodosin (Silo), for the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia (male LUTS/BPH)."5.16[Comparison of naftopidil and silodosin in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, crossover study]. ( Asakura, T; Hashiba, T; Jinza, S; Masuda, M; Masuko, H, 2012)
"To investigate the incidence of ejaculatory disorders caused by naftopidil and tamsulosin in patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH)."5.14Ejaculatory disorders caused by alpha-1 blockers for patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: comparison of naftopidil and tamsulosin in a randomized multicenter study. ( Furuya, R; Iwasawa, A; Masumori, N; Mori, M; Sonoda, T; Tsukamoto, T, 2009)
"We examined the tolerability of dosage methods of naftopidil in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH/male LUTS)."5.14A prospective, randomized, controlled, multicenter study of naftopidil for treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: 75 mg once daily in the evening compared to 25 mg thrice daily. ( Kazama, T; Kimura, H; Nozaki, T; Okumura, A; Tsuritani, S, 2010)
"To compare the efficacy of two alpha(1)-adrenoceptor antagonists, alpha(1A)-adrenoceptor-selective tamsulosin hydrochloride and alpha(1D)-adrenoceptor-selective naftopidil, in the treatment of lower urinary tract symptoms (LUTS) with benign prostatic hyperplasia (BPH)."5.12Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: a randomized crossover study. ( Deguchi, T; Ishihara, S; Masue, T; Miwa, K; Nishino, Y; Takahashi, Y, 2006)
"The present study investigated the efficacy, safety, and utility of starting an alpha(1d)-selective antagonist, naftopidil, at 75 or 25 mg/day in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)."5.12Comparison of 25 and 75 mg/day naftopidil for lower urinary tract symptoms associated with benign prostatic hyperplasia: a prospective, randomized controlled study. ( Kumon, H; Nasu, Y; Takamoto, H; Watanabe, T; Yokoyama, T, 2006)
"We studied the efficacy of naftopidil (50 mg/day) on nocturia associated with benign prostatic hyperplasia in 35 patients (62-80 years old)."5.10[Clinical effects of naftopidil on nocturia associated with benign prostatic hyperplasia]. ( Araki, I; Fukuzawa, S; Hashimura, T; Soeda, T; Sugino, Y; Takeuchi, H; Taki, Y, 2003)
"Naftopidil, a phenylpiperazine derivative, is a novel alpha 1-adrenoceptor antagonist and is new drug for the bladder outlet obstruction in patients with benign prostatic hyperplasia (BPH)."4.80[Pharmacological properties of naftopidil, a drug for treatment of the bladder outlet obstruction for patients with benign prostatic hyperplasia]. ( Ikegaki, I, 2000)
"We examined the effectiveness of naftopidil in 81 patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)."3.74[The effectiveness of naftopidil in patients with benign prostatic hyperplasia evaluated by QOL index]. ( Hamano, S; Murakami, S; Nakatsu, H; Naoi, M; Sekiyama, K; Suzuki, N; Tanaka, M, 2007)
"Naftopidil was administered to 67 patients with benign prostatic hyperplasia (BPH) for 12 months."3.72[Long-term efficacy of naftopidil for treatment of lower urinary tract symptoms with benign prostatic hyperplasia]. ( Akasaka, T; Fujishima, M; Funaki, H; Hirano, S; Iinuma, M; Kudou, T; Ohinata, M; Suzuki, A, 2003)
"Tamsulosin was more effective than naftopidil on intermittency, nocturia and quality of life scores."2.73Crossover comparison study on the therapeutic effects of tamsulosin hydrochloride and naftopidil in lower urinary tract symptoms associated with benign prostatic hyperplasia. ( Hosokawa, Y; Kishino, T; Momose, H; Ono, T; Oyama, N, 2007)
"Naftopidil was administered for three months to the patients with BPH who had nocturia with a urinary frequency of two or more times."1.32[Etiology of nocturia and clinical efficacy of naftopidil on nocturia in patients with benign prostatic hyperplasia--analysis of frequency volume charts]. ( Furuhata, A; Hirokawa, M; Hiromoto, Y; Ikeda, A; Kawasaki, C; Masuda, M; Nakayama, K; Satomi, Y; Shiramizu, M, 2004)
" KT-611 at a dosage of once or twice a day was evaluated for its effects on 49 patients with benign prostatic hypertrophy."1.28[Effect of KT-611 (Naftopidil) on the contraction of human prostatic tissue and its use in benign prostatic obstruction]. ( Fukaya, Y; Itou, K; Kameoka, H; Kuma, Y; Kumakawa, K; Shiraiwa, Y; Yamaguchi, O; Yamanaka, N; Yokota, T; Yokoyama, J, 1991)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's12 (60.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ukimura, O1
Kanazawa, M1
Fujihara, A1
Kamoi, K1
Okihara, K1
Miki, T1
Ishizaka, K1
Machida, T1
Tanaka, M2
Kawamura, N1
Nakamura, K1
Kihara, K1
Masumori, N1
Tsukamoto, T1
Iwasawa, A1
Furuya, R1
Sonoda, T1
Mori, M1
Tsuritani, S1
Nozaki, T1
Okumura, A1
Kimura, H1
Kazama, T1
Yokoyama, T2
Hara, R1
Fukumoto, K1
Fujii, T1
Jo, Y1
Miyaji, Y1
Nagai, A1
Sone, A1
Yamaguchi, S1
Osanai, H1
Numata, A1
Watanabe, M1
Kakizaki, H1
Park, WH1
Ishizuka, O1
Funahashi, Y1
Masuda, M2
Jinza, S1
Masuko, H1
Asakura, T1
Hashiba, T1
Akasaka, T1
Funaki, H1
Hirano, S1
Ohinata, M1
Fujishima, M1
Kudou, T1
Suzuki, A1
Iinuma, M1
Sugino, Y1
Fukuzawa, S1
Takeuchi, H1
Taki, Y1
Hashimura, T1
Soeda, T1
Araki, I1
Ikemoto, I1
Kiyota, H1
Ohishi, Y1
Abe, K1
Goto, H1
Kishimoto, K1
Miki, K1
Nakayama, K1
Hiromoto, Y1
Hirokawa, M1
Satomi, Y1
Shiramizu, M1
Furuhata, A1
Ikeda, A1
Kawasaki, C1
Nishino, Y1
Masue, T1
Miwa, K1
Takahashi, Y1
Ishihara, S1
Deguchi, T1
Kumon, H1
Nasu, Y1
Takamoto, H1
Watanabe, T1
Nakatsu, H1
Naoi, M1
Sekiyama, K1
Hamano, S1
Suzuki, N1
Murakami, S1
Momose, H1
Hosokawa, Y1
Kishino, T1
Ono, T1
Oyama, N1
Ikegaki, I1
Yamanaka, N1
Yamaguchi, O1
Kameoka, H1
Fukaya, Y1
Yokota, T1
Shiraiwa, Y1
Yokoyama, J1
Kumakawa, K1
Itou, K1
Kuma, Y1

Reviews

1 review available for naftopidil and Urination Disorders

ArticleYear
[Pharmacological properties of naftopidil, a drug for treatment of the bladder outlet obstruction for patients with benign prostatic hyperplasia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2000, Volume: 116, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Animals; Binding, Competitive; Dogs; Humans; Male; Naphthalenes;

2000

Trials

11 trials available for naftopidil and Urination Disorders

ArticleYear
Naftopidil versus tamsulosin hydrochloride for lower urinary tract symptoms associated with benign prostatic hyperplasia with special reference to the storage symptom: a prospective randomized controlled study.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:12

    Topics: Adrenergic alpha-Antagonists; Aged; Humans; Male; Middle Aged; Naphthalenes; Piperazines; Prospectiv

2008
Ejaculatory disorders caused by alpha-1 blockers for patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: comparison of naftopidil and tamsulosin in a randomized multicenter study.
    Urologia internationalis, 2009, Volume: 83, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Ejaculation; Humans; Male; Middle Aged; Naphthalenes; Piperazine

2009
A prospective, randomized, controlled, multicenter study of naftopidil for treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: 75 mg once daily in the evening compared to 25 mg thrice daily.
    Urologia internationalis, 2010, Volume: 85, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Drug Administration Schedule; Huma

2010
Effects of three types of alpha-1 adrenoceptor blocker on lower urinary tract symptoms and sexual function in males with benign prostatic hyperplasia.
    International journal of urology : official journal of the Japanese Urological Association, 2011, Volume: 18, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Ejaculation; Erectile Dysfunction;

2011
α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy.
    International journal of urology : official journal of the Japanese Urological Association, 2013, Volume: 20, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Dose-Response Relationship, Drug; Humans; Male; Middl

2013
[Comparison of naftopidil and silodosin in the treatment of male lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, crossover study].
    Hinyokika kiyo. Acta urologica Japonica, 2012, Volume: 58, Issue:12

    Topics: Adrenergic alpha-Antagonists; Cross-Over Studies; Humans; Indoles; Male; Naphthalenes; Piperazines;

2012
[Clinical effects of naftopidil on nocturia associated with benign prostatic hyperplasia].
    Hinyokika kiyo. Acta urologica Japonica, 2003, Volume: 49, Issue:8

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Drug Administration Schedule; Humans; Male; M

2003
Usefulness of tamsulosin hydrochloride and naftopidil in patients with urinary disturbances caused by benign prostatic hyperplasia: a comparative, randomized, two-drug crossover study.
    International journal of urology : official journal of the Japanese Urological Association, 2003, Volume: 10, Issue:11

    Topics: Adrenergic alpha-Antagonists; Aged; Cross-Over Studies; Dizziness; Headache; Humans; Hypotension, Or

2003
Comparison of two alpha1-adrenoceptor antagonists, naftopidil and tamsulosin hydrochloride, in the treatment of lower urinary tract symptoms with benign prostatic hyperplasia: a randomized crossover study.
    BJU international, 2006, Volume: 97, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Cross-Over Studies; Humans; Male; Naphthalenes; Piperazines; Pro

2006
Comparison of 25 and 75 mg/day naftopidil for lower urinary tract symptoms associated with benign prostatic hyperplasia: a prospective, randomized controlled study.
    International journal of urology : official journal of the Japanese Urological Association, 2006, Volume: 13, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule;

2006
Crossover comparison study on the therapeutic effects of tamsulosin hydrochloride and naftopidil in lower urinary tract symptoms associated with benign prostatic hyperplasia.
    Drugs of today (Barcelona, Spain : 1998), 2007, Volume: 43 Suppl A

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Cross-Over Studies; Drug Therapy, Combination

2007

Other Studies

8 other studies available for naftopidil and Urination Disorders

ArticleYear
Clinical efficacy of naftopidil on lower urinary tract symptoms after radical prostatectomy.
    International journal of urology : official journal of the Japanese Urological Association, 2009, Volume: 16, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Drug Admini

2009
Editorial comment from Dr Park to α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy.
    International journal of urology : official journal of the Japanese Urological Association, 2013, Volume: 20, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Humans; Male; Naphthalenes; Piperazines; Prostatic Hyperpla

2013
Editorial comment from Dr Ishizuka to α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy.
    International journal of urology : official journal of the Japanese Urological Association, 2013, Volume: 20, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Humans; Male; Naphthalenes; Piperazines; Prostatic Hyperpla

2013
Editorial comment from Dr Funahashi to α1D/A-adrenoceptor antagonist naftopidil for the male lower urinary tract symptoms associated with benign prostatic hyperplasia: efficacy of dose increase therapy.
    International journal of urology : official journal of the Japanese Urological Association, 2013, Volume: 20, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Humans; Male; Naphthalenes; Piperazines; Prostatic Hyperpla

2013
[Long-term efficacy of naftopidil for treatment of lower urinary tract symptoms with benign prostatic hyperplasia].
    Hinyokika kiyo. Acta urologica Japonica, 2003, Volume: 49, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Drug Administration Schedule; Humans; Male; M

2003
[Etiology of nocturia and clinical efficacy of naftopidil on nocturia in patients with benign prostatic hyperplasia--analysis of frequency volume charts].
    Hinyokika kiyo. Acta urologica Japonica, 2004, Volume: 50, Issue:5

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Circadian Rhythm; Drug Administration Schedul

2004
[The effectiveness of naftopidil in patients with benign prostatic hyperplasia evaluated by QOL index].
    Hinyokika kiyo. Acta urologica Japonica, 2007, Volume: 53, Issue:1

    Topics: Adrenergic alpha-Antagonists; Aged; Drug Administration Schedule; Humans; Male; Middle Aged; Naphtha

2007
[Effect of KT-611 (Naftopidil) on the contraction of human prostatic tissue and its use in benign prostatic obstruction].
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:12

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Drug Administration Schedule; Humans;

1991