Page last updated: 2024-10-31

nafronyl and Raynaud Disease

nafronyl has been researched along with Raynaud Disease in 5 studies

Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

Raynaud Disease: An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.

Research Excerpts

ExcerptRelevanceReference
"Testicular cancer has a favorable prognosis in the majority of patients due to the excellent susceptibility to chemotherapy with cisplatin, etoposide and bleomycin (BEP), which is commonly administered over 3-4 cycles of treatment."1.33Acral necrosis after inadequate excessive administration of bleomycin in a testicular cancer patient. ( Bolte, O; Ganser, A; Grünwald, V; Schöffski, P; Wiebe, S, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pope, J1
Grünwald, V1
Bolte, O1
Wiebe, S1
Ganser, A1
Schöffski, P1
Gaylarde, PM2
Tan, OT2
Sarkany, I2
Nilsen, KH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-controlled Trial of St.John's Wort(a Natural Health Product) in the Treatment on Raynaud's Phenomenon[NCT00351117]Phase 320 participants (Actual)Interventional2007-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nafronyl and Raynaud Disease

ArticleYear
Raynaud's phenomenon (primary).
    Clinical evidence, 2003, Issue:9

    Topics: Amlodipine; Diltiazem; Humans; Nafronyl; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agent

2003

Trials

1 trial available for nafronyl and Raynaud Disease

ArticleYear
Effects of naftidrofuryl on microcirculatory cold sensitivity in Raynaud's phenomenon.
    British medical journal, 1979, Jan-06, Volume: 1, Issue:6155

    Topics: Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Furans; Humans; Microcirculation; N

1979

Other Studies

3 other studies available for nafronyl and Raynaud Disease

ArticleYear
Acral necrosis after inadequate excessive administration of bleomycin in a testicular cancer patient.
    Onkologie, 2005, Volume: 28, Issue:1

    Topics: Adult; Antineoplastic Agents; Bleomycin; Clonidine; Dose-Response Relationship, Drug; Drug Administr

2005
Blood flow changes with naftidrofuryl in systemic sclerosis and Raynaud's phenomenon.
    The British journal of dermatology, 1980, Volume: 102, Issue:1

    Topics: Adult; Aged; Body Temperature Regulation; Female; Fingers; Forearm; Furans; Humans; Leg; Male; Middl

1980
Effect of naftidrofuryl oxalate (praxilene) on peripheral circulation measured by calorimetry.
    The Australasian journal of dermatology, 1978, Volume: 19, Issue:2

    Topics: Adult; Body Temperature; Calorimetry; Female; Fingers; Furans; Humans; Injections, Intravenous; Male

1978