Page last updated: 2024-10-31

nafronyl and Pain

nafronyl has been researched along with Pain in 6 studies

Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"A systematic review and network meta-analysis was undertaken to consider the evidence for the efficacy and tolerability of placebo, cilostazol, naftidrofuryl oxalate and pentoxifylline in patients with intermittent claudication due to peripheral arterial disease (PAD)."8.88Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. ( Harnan, S; Meng, Y; Michaels, J; Simpson, E; Squires, H; Stansby, G; Stevens, JW; Thomas, S, 2012)
"A systematic review and network meta-analysis was undertaken to consider the evidence for the efficacy and tolerability of placebo, cilostazol, naftidrofuryl oxalate and pentoxifylline in patients with intermittent claudication due to peripheral arterial disease (PAD)."4.88Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. ( Harnan, S; Meng, Y; Michaels, J; Simpson, E; Squires, H; Stansby, G; Stevens, JW; Thomas, S, 2012)
"The Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched May 2012) and CENTRAL (2012, Issue 4)."2.48Intravenous naftidrofuryl for critical limb ischaemia. ( Bradbury, A; Fowkes, G; Smith, FB, 2012)
"Authors and companies were approached for additional information and individual patient data."2.45Naftidrofuryl for intermittent claudication: meta-analysis based on individual patient data. ( De Backer, T; Lehert, P; Van Bortel, L; Vander Stichele, R, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Backer, T1
Vander Stichele, R1
Lehert, P2
Van Bortel, L1
Smith, FB1
Bradbury, A1
Fowkes, G1
Stevens, JW1
Simpson, E1
Harnan, S1
Squires, H1
Meng, Y1
Thomas, S1
Michaels, J1
Stansby, G1
Greenhalgh, RM1
Kieffer, E1
Bahnini, A1
Mouren, X1
Gamand, S1
Spengel, F1
Clément, D1
Boccalon, H1
Liard, F1
Brown, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)[NCT03883412]Phase 460 participants (Anticipated)Interventional2019-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for nafronyl and Pain

ArticleYear
Naftidrofuryl for intermittent claudication: meta-analysis based on individual patient data.
    BMJ (Clinical research ed.), 2009, Mar-10, Volume: 338

    Topics: Female; Humans; Intermittent Claudication; Male; Middle Aged; Nafronyl; Pain; Randomized Controlled

2009
Intravenous naftidrofuryl for critical limb ischaemia.
    The Cochrane database of systematic reviews, 2012, Jul-11, Issue:7

    Topics: Amputation, Surgical; Extremities; Female; Humans; Infusions, Intravenous; Ischemia; Male; Nafronyl;

2012
Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication.
    The British journal of surgery, 2012, Volume: 99, Issue:12

    Topics: Cilostazol; Humans; Intermittent Claudication; Nafronyl; Pain; Pentoxifylline; Peripheral Vascular D

2012

Trials

3 trials available for nafronyl and Pain

ArticleYear
Naftidrofuryl for ischaemic rest pain: a controlled trial.
    The British journal of surgery, 1981, Volume: 68, Issue:4

    Topics: Aged; Clinical Trials as Topic; Furans; Humans; Ischemia; Leg; Middle Aged; Nafronyl; Pain; Placebos

1981
A new study demonstrates the efficacy of naftidrofuryl in the treatment of intermittent claudication. Findings of the Naftidrofuryl Clinical Ischemia Study (NCIS).
    International angiology : a journal of the International Union of Angiology, 2001, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Intermitt

2001
Findings of the Naftidrofuryl in Quality of Life (NIQOL) European study program.
    International angiology : a journal of the International Union of Angiology, 2002, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Europe; Female; Follow-Up Studies; Humans; Intermittent Claudication

2002