nafronyl and Pain
nafronyl has been researched along with Pain in 6 studies
Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "A systematic review and network meta-analysis was undertaken to consider the evidence for the efficacy and tolerability of placebo, cilostazol, naftidrofuryl oxalate and pentoxifylline in patients with intermittent claudication due to peripheral arterial disease (PAD)." | 8.88 | Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. ( Harnan, S; Meng, Y; Michaels, J; Simpson, E; Squires, H; Stansby, G; Stevens, JW; Thomas, S, 2012) |
| "A systematic review and network meta-analysis was undertaken to consider the evidence for the efficacy and tolerability of placebo, cilostazol, naftidrofuryl oxalate and pentoxifylline in patients with intermittent claudication due to peripheral arterial disease (PAD)." | 4.88 | Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. ( Harnan, S; Meng, Y; Michaels, J; Simpson, E; Squires, H; Stansby, G; Stevens, JW; Thomas, S, 2012) |
| "The Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched May 2012) and CENTRAL (2012, Issue 4)." | 2.48 | Intravenous naftidrofuryl for critical limb ischaemia. ( Bradbury, A; Fowkes, G; Smith, FB, 2012) |
| "Authors and companies were approached for additional information and individual patient data." | 2.45 | Naftidrofuryl for intermittent claudication: meta-analysis based on individual patient data. ( De Backer, T; Lehert, P; Van Bortel, L; Vander Stichele, R, 2009) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| De Backer, T | 1 |
| Vander Stichele, R | 1 |
| Lehert, P | 2 |
| Van Bortel, L | 1 |
| Smith, FB | 1 |
| Bradbury, A | 1 |
| Fowkes, G | 1 |
| Stevens, JW | 1 |
| Simpson, E | 1 |
| Harnan, S | 1 |
| Squires, H | 1 |
| Meng, Y | 1 |
| Thomas, S | 1 |
| Michaels, J | 1 |
| Stansby, G | 1 |
| Greenhalgh, RM | 1 |
| Kieffer, E | 1 |
| Bahnini, A | 1 |
| Mouren, X | 1 |
| Gamand, S | 1 |
| Spengel, F | 1 |
| Clément, D | 1 |
| Boccalon, H | 1 |
| Liard, F | 1 |
| Brown, T | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)[NCT03883412] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for nafronyl and Pain
| Article | Year |
|---|---|
Naftidrofuryl for intermittent claudication: meta-analysis based on individual patient data.
Topics: Female; Humans; Intermittent Claudication; Male; Middle Aged; Nafronyl; Pain; Randomized Controlled | 2009 |
Intravenous naftidrofuryl for critical limb ischaemia.
Topics: Amputation, Surgical; Extremities; Female; Humans; Infusions, Intravenous; Ischemia; Male; Nafronyl; | 2012 |
Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication.
Topics: Cilostazol; Humans; Intermittent Claudication; Nafronyl; Pain; Pentoxifylline; Peripheral Vascular D | 2012 |
Trials
3 trials available for nafronyl and Pain
| Article | Year |
|---|---|
Naftidrofuryl for ischaemic rest pain: a controlled trial.
Topics: Aged; Clinical Trials as Topic; Furans; Humans; Ischemia; Leg; Middle Aged; Nafronyl; Pain; Placebos | 1981 |
A new study demonstrates the efficacy of naftidrofuryl in the treatment of intermittent claudication. Findings of the Naftidrofuryl Clinical Ischemia Study (NCIS).
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Intermitt | 2001 |
Findings of the Naftidrofuryl in Quality of Life (NIQOL) European study program.
Topics: Adult; Aged; Aged, 80 and over; Europe; Female; Follow-Up Studies; Humans; Intermittent Claudication | 2002 |