nafronyl has been researched along with Ischemia in 31 studies
Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anti-hypoxic effect of cinnarizine was studied using the following experimental methods: hypobaric and anoxic hypoxia in mice, complete ischemia by decapitation in mice and hemic hypoxia in rats." | 3.67 | Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin. ( Milanova, D; Nikolov, R; Nikolova, M, 1984) |
| " Evaluation criteria were pain assessment using a visual analogue scale, analgesic consumption considering both the power (WHO scale: level I paracetamol, level II dextropropoxyphene, level III morphine) and the dosage of the analgesic used (analgesic score), index of therapeutic success including the level of pain reduction and the absence of analgesic use." | 2.67 | [Evaluation of the analgesic effect of naftidrofuryl in permanent ischemia in patients with arterial diseases. Double-blind versus placebo study]. ( Glanddier, G; Guidicelli, H; Mosnier, M; Testart, J, 1994) |
| "The Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched May 2012) and CENTRAL (2012, Issue 4)." | 2.48 | Intravenous naftidrofuryl for critical limb ischaemia. ( Bradbury, A; Fowkes, G; Smith, FB, 2012) |
| " Long term use of these drugs may prevent deterioration in those patients with progressive disease, and controlled trials on this aspect of treatment are now required." | 2.36 | Can drugs help patients with lower limb ischaemia? ( Bell, PR; Boobis, LH, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (58.06) | 18.7374 |
| 1990's | 8 (25.81) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vietto, V | 1 |
| Franco, JV | 1 |
| Saenz, V | 1 |
| Cytryn, D | 1 |
| Chas, J | 1 |
| Ciapponi, A | 1 |
| Kuznetsov, MR | 1 |
| Kosykh, IV | 1 |
| Iumin, SM | 1 |
| Kunitsyn, NV | 1 |
| Kuznetsova, VF | 1 |
| Tolstikhin, VIu | 1 |
| Magnitskiĭ, LA | 1 |
| Smith, FB | 2 |
| Bradbury, A | 1 |
| Fowkes, G | 1 |
| Boobis, LH | 1 |
| Bell, PR | 1 |
| Nikolov, R | 1 |
| Nikolova, M | 1 |
| Milanova, D | 1 |
| Mustapha, NM | 1 |
| Jain, SK | 1 |
| Dudley, P | 1 |
| Redhead, RG | 1 |
| Awwad, AM | 1 |
| White, RJ | 1 |
| Webster, MH | 1 |
| Vance, JP | 1 |
| Meehan, SE | 1 |
| Preece, PE | 1 |
| Walker, WF | 1 |
| Greenhalgh, RM | 1 |
| Wong, AL | 1 |
| McBain, GC | 1 |
| Drummond, M | 1 |
| Davies, L | 1 |
| Testart, J | 1 |
| Guidicelli, H | 1 |
| Glanddier, G | 1 |
| Mosnier, M | 2 |
| Michiels, C | 1 |
| Arnould, T | 1 |
| Janssens, D | 1 |
| Alexandre, I | 1 |
| Houbion, A | 1 |
| Remacle, J | 1 |
| Mouren, X | 1 |
| Caillard, P | 1 |
| Bensoussan, JJ | 1 |
| Massonneau, M | 1 |
| Gamand, S | 1 |
| Stevens, WH | 1 |
| Lamm, K | 1 |
| Arnold, W | 1 |
| Bradbury, AW | 1 |
| Fowkes, FG | 1 |
| Cosnier, D | 1 |
| Cheucle, M | 1 |
| Rispat, G | 1 |
| Streichenberger, G | 1 |
| Stadnik, J | 1 |
| Cieślik, R | 1 |
| Jarochowski, M | 1 |
| Macyszyn, R | 1 |
| Davies, AH | 1 |
| Magee, TR | 1 |
| Baird, RN | 1 |
| Horrocks, M | 1 |
| Cooper, GG | 1 |
| Masser, MR | 1 |
| Moir, GC | 1 |
| Salim, AS | 1 |
| Kiesewetter, H | 1 |
| Jung, F | 1 |
| Blume, J | 1 |
| Bulling, B | 1 |
| Gerhards, M | 1 |
| Alnot, JY | 1 |
| Whabi, S | 1 |
| Oberlin, C | 1 |
| Huten, D | 1 |
| Grossin, M | 1 |
| Nakamuta, H | 1 |
| Muguruma, K | 1 |
| Koida, M | 1 |
| Hiramatsu, Y | 1 |
| Ogawa, Y | 1 |
| Fellmann, N | 1 |
| Fabry, R | 1 |
| Coudert, J | 1 |
| Vayssairat, M | 1 |
| Baudot, N | 1 |
| Sainte-Beuve, C | 1 |
| Leonardo, G | 1 |
| Arpaia, MR | 1 |
| Del Guercio, R | 1 |
| Barker, JH | 1 |
| Menger, MD | 1 |
| Sack, FU | 1 |
| Messmer, K | 1 |
| Chachques, JC | 1 |
| Fabiani, JN | 1 |
| Acar, C | 1 |
| Jebara, VA | 1 |
| Dreyfus, G | 1 |
| Carpentier, A | 1 |
5 reviews available for nafronyl and Ischemia
| Article | Year |
|---|---|
Prostanoids for critical limb ischaemia.
Topics: Alprostadil; Amputation, Surgical; Epoprostenol; Humans; Iloprost; Ischemia; Leg; Leg Ulcer; Nafrony | 2018 |
[Use of naftidrofuryl in angiology].
Topics: Humans; Ischemia; Nafronyl; Randomized Controlled Trials as Topic; Receptors, Serotonin, 5-HT2; Sero | 2014 |
Intravenous naftidrofuryl for critical limb ischaemia.
Topics: Amputation, Surgical; Extremities; Female; Humans; Infusions, Intravenous; Ischemia; Male; Nafronyl; | 2012 |
Can drugs help patients with lower limb ischaemia?
Topics: Aged; Arteriosclerosis; Aspirin; Cholesterol; Collateral Circulation; Female; Hemodynamics; Humans; | 1982 |
Intravenous naftidrofuryl for critical limb ischaemia.
Topics: Extremities; Humans; Infusions, Intravenous; Ischemia; Nafronyl; Peripheral Vascular Diseases; Serot | 2000 |
6 trials available for nafronyl and Ischemia
| Article | Year |
|---|---|
The usefulness of naftidrofuryl in severe peripheral ischaemia--a symptomatic assessment using linear analogue scales.
Topics: Aged; Clinical Trials as Topic; Female; Furans; Humans; Ischemia; Male; Middle Aged; Nafronyl; Throm | 1982 |
Naftidrofuryl for ischaemic rest pain: a controlled trial.
Topics: Aged; Clinical Trials as Topic; Furans; Humans; Ischemia; Leg; Middle Aged; Nafronyl; Pain; Placebos | 1981 |
[Evaluation of the analgesic effect of naftidrofuryl in permanent ischemia in patients with arterial diseases. Double-blind versus placebo study].
Topics: Aged; Aged, 80 and over; Analgesics; Arterial Occlusive Diseases; Double-Blind Method; Female; Human | 1994 |
The effect of naftidrofuryl on transcutaneous oxygen tension during a treadmill test in patients with peripheral arterial occlusive disease.
Topics: Aged; Area Under Curve; Double-Blind Method; Exercise Test; Female; Humans; Intermittent Claudicatio | 1998 |
Calf sweat lactate in peripheral arterial occlusive disease.
Topics: Aged; Arterial Occlusive Diseases; Biomarkers; Double-Blind Method; Female; Furans; Humans; Ischemia | 1989 |
Why does placebo improve severe limb ischaemia?
Topics: Blood Gas Monitoring, Transcutaneous; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1988 |
20 other studies available for nafronyl and Ischemia
| Article | Year |
|---|---|
Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin.
Topics: Animals; Atmospheric Pressure; Brain; Cinnarizine; Drug Interactions; Epoprostenol; Hypoxia; Ischemi | 1984 |
The effect of oxygen inhalation and intravenous naftidrofuryl on the transcutaneous partial oxygen pressure in ischaemic lower limbs.
Topics: Adolescent; Adult; Combined Modality Therapy; Furans; Humans; Infusions, Parenteral; Ischemia; Leg; | 1984 |
Effect of naftidrofuryl oxalate (Praxilene) on blood flow in the experimental saphenous flap model.
Topics: Animals; Blood Flow Velocity; Blood Vessels; Dogs; Furans; Ischemia; Nafronyl; Skin; Surgical Flaps | 1983 |
The importance of personality measurement in the assessment of response to treatment for ischaemic rest pain.
Topics: Aged; Amputation, Surgical; Bed Rest; Extraversion, Psychological; Extremities; Female; Follow-Up St | 1980 |
Economic evaluation of drugs in peripheral vascular disease and stroke.
Topics: Cerebrovascular Disorders; Cost-Benefit Analysis; Decision Trees; Economics, Pharmaceutical; Health | 1994 |
Effects of naftidrofuryl on hypoxia-induced activation and mortality of human endothelial cells.
Topics: Adenosine Triphosphate; Arachidonic Acid; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cytoso | 1993 |
The effect of blood flow promoting drugs on cochlear blood flow, perilymphatic pO(2) and auditory function in the normal and noise-damaged hypoxic and ischemic guinea pig inner ear.
Topics: Animals; Betahistine; Cochlea; Ear, Inner; Female; Ginkgo biloba; Guinea Pigs; Hearing Loss, Noise-I | 2000 |
Naftidrofuryl (Praxilene) in peripheral vascular disease.
Topics: Animals; Furans; Humans; Intermittent Claudication; Ischemia; Leg; Male; Mice; Middle Aged; Nafronyl | 1979 |
Influence of hypercapnia on the cerebrovascular activities of some drugs used in the treatment of cerebral ischemia.
Topics: Animals; Brain; Cerebrovascular Circulation; Cinnarizine; Heptaminol; Hypercapnia; Ischemia; Nafrony | 1977 |
[Trial treatment of atherosclerosis--derived ischemia of the lower extremities with dusodril (author's transl)].
Topics: Arteriosclerosis; Diabetes Complications; Furans; Humans; Ischemia; Leg; Nafronyl | 1977 |
Praxilene (naftidrofuryl oxalate) as an alternative for the augmentation of femoro-distal bypass blood flow.
Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Femoral Artery; Humans; Ischemia; Leg; Middle A | 1992 |
Naftidrofluryl dose and vascular resistance.
Topics: Dose-Response Relationship, Drug; Femoral Artery; Humans; Injections, Intra-Arterial; Ischemia; Leg; | 1992 |
A randomised controlled study to evaluate the effect of Naftidrofuryl in a rat ischaemic skin flap model.
Topics: Animals; Drug Evaluation; Graft Survival; Ischemia; Male; Nafronyl; Random Allocation; Rats; Rats, I | 1991 |
Naftidrofuryl protects the rat against chronic gastric ulceration.
Topics: Animals; Female; Gastric Acid; Gastric Mucosa; Ischemia; Male; Nafronyl; Rats; Rats, Inbred Strains; | 1991 |
Conservative drug therapy and walking exercise in stage IIb peripheral arterial occlusion disease.
Topics: Adult; Aged; Arm; Arterial Occlusive Diseases; Combined Modality Therapy; Female; Furans; Hemodiluti | 1986 |
[Effects of transient ischemia on inguinal flaps of the rat. Study of cutaneous microvascularization and the effects of vasodilator agents].
Topics: Animals; Ischemia; Microcirculation; Nafronyl; Rats; Skin; Surgical Flaps; Vasodilator Agents | 1986 |
Ischemia-induced changes in brain levels of monoamines and their metabolites of mice and rats: some protective effects of naftidrofuryl.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Brain; Disease Models, Animal; Dopamine; Ischemia; M | 1989 |
A new method for the quantitative assessment of arterial insufficiency of the limbs: cutaneous postischemic hyperemia test by laser Doppler.
Topics: Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Blood Pressure; Female; Humans; Hype | 1987 |
[Nutritive skin circulation in partial ischemia: effect of various vasoactive substances].
Topics: Animals; Furans; Ischemia; Mice; Mice, Hairless; Nafronyl; Pentoxifylline; Pyrrolidines; Regional Bl | 1988 |
[Histochemical quantification of muscular ischemia: effect of treatment with naftidrofuryl].
Topics: Animals; Energy Metabolism; Hindlimb; Histocytochemistry; Ischemia; Male; Mitochondria, Muscle; Musc | 1988 |