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nafronyl and Cerebrovascular Disorders

nafronyl has been researched along with Cerebrovascular Disorders in 17 studies

Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.

Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

Research Excerpts

ExcerptRelevanceReference
" It covers firstly the general problems of stroke, dementia and 'common symptoms' of the elderly, and then looks in detail at those compounds which have to date attracted most attention (ergot derivatives, cinnarizine, flunarizine, vincamine, eburnamonine, naftidrofuryl, oxpentifylline, piracetam and citicoline), as well as those which are currently considered investigational (choline and lecithin)."6.15'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders. ( Spagnoli, A; Tognoni, G, 1983)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's5 (29.41)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Spagnoli, A1
Tognoni, G1
Kobayashi, S1
Yamaguchi, S1
Katsube, T1
Okada, K1
Kitani, M1
Murao, M1
Tsunematsu, T1
Cook, P1
James, I1
Drummond, M1
Davies, L1
Akopov, SE1
Darbinian, VZh1
Ovanesian, GO1
Admani, AK1
Perkin, GD1
Judge, TG1
Steiner, T1
Capildeo, R1
Rose, FC1
Cox, JR1
Steiner, TJ2
Capon, A1
Lehert, P1
Opsomer, L1
Gray, CS1
French, JM1
Venables, GS1
Cartlidge, NE1
James, OF1
Bates, D1
Sandercock, P1

Reviews

4 reviews available for nafronyl and Cerebrovascular Disorders

ArticleYear
'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders.
    Drugs, 1983, Volume: 26, Issue:1

    Topics: Adult; Aged; Cerebrovascular Disorders; Cinnarizine; Clinical Trials as Topic; Cytidine Diphosphate

1983
Drug therapy: cerebral vasodilators (first of two parts).
    The New England journal of medicine, 1981, Dec-17, Volume: 305, Issue:25

    Topics: Aged; Aging; Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Cycla

1981
Naftidrofuryl after acute stroke: a review and a hypothesis.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 3

    Topics: Acute Disease; Cerebrovascular Disorders; Clinical Trials as Topic; Humans; Nafronyl

1990
Naftidrofuryl (Praxilene).
    Drug and therapeutics bulletin, 1988, Apr-05, Volume: 26, Issue:7

    Topics: Acute Disease; Cerebrovascular Disorders; Dementia; Furans; Humans; Nafronyl

1988

Trials

11 trials available for nafronyl and Cerebrovascular Disorders

ArticleYear
'Cerebroactive' drugs. Clinical pharmacology and therapeutic role in cerebrovascular disorders.
    Drugs, 1983, Volume: 26, Issue:1

    Topics: Adult; Aged; Cerebrovascular Disorders; Cinnarizine; Clinical Trials as Topic; Cytidine Diphosphate

1983
Effects of naftidrofuryl on the time course of the regional cerebral blood flow in acute ischemic stroke.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:11

    Topics: Adult; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders;

1984
Drug therapy: cerebral vasodilators (first of two parts).
    The New England journal of medicine, 1981, Dec-17, Volume: 305, Issue:25

    Topics: Aged; Aging; Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Cycla

1981
New approach to treatment of recent stroke.
    British medical journal, 1978, Dec-16, Volume: 2, Issue:6153

    Topics: Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Female; Furans; Huma

1978
New approach to treatment of recent stroke?
    British medical journal, 1979, May-12, Volume: 1, Issue:6173

    Topics: Cerebral Hemorrhage; Cerebral Infarction; Cerebrovascular Disorders; Clinical Trials as Topic; Drug

1979
Treatment of acute stroke.
    The Medical journal of Australia, 1979, Jun-30, Volume: 1, Issue:13

    Topics: Cerebrovascular Disorders; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Glycerol; H

1979
Double-blind evaluation of naftidrofuryl in treating elderly confused hospitalised patients.
    Gerontologia clinica, 1975, Volume: 17, Issue:3

    Topics: Aged; Attitude of Health Personnel; Cerebrovascular Disorders; Clinical Trials as Topic; Cognition D

1975
Naftidrofuryl in the treatment of subacute stroke.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cerebrovascular Disorders; Double-Blind Method; Femal

1990
A randomized double-blind controlled trial of naftidrofuryl in acute stroke.
    Age and ageing, 1990, Volume: 19, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Cerebrovascular Disorders; Delayed-Action Preparat

1990
Naftidrofuryl in the treatment of recent stroke. Results of a controlled clinical trial.
    VASA. Supplementum, 1988, Volume: 24

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Cerebrovascular Disorders; Clinical Trials as Topi

1988
Important new treatments for acute ischaemic stroke?
    British medical journal (Clinical research ed.), 1987, Nov-14, Volume: 295, Issue:6608

    Topics: Acute Disease; Cerebrovascular Disorders; Clinical Trials as Topic; Glycerol; Humans; Nafronyl; Nimo

1987

Other Studies

4 other studies available for nafronyl and Cerebrovascular Disorders

ArticleYear
Economic evaluation of drugs in peripheral vascular disease and stroke.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 3

    Topics: Cerebrovascular Disorders; Cost-Benefit Analysis; Decision Trees; Economics, Pharmaceutical; Health

1994
[Blood filterability and its correction with naftidrofuril in patients with cerebrovascular diseases].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1996, Volume: 96, Issue:1

    Topics: Acute Disease; Aged; Brain Ischemia; Cerebrovascular Disorders; Drug Evaluation; Erythrocyte Deforma

1996
The therapeutic uses of naftidrofuryl (Praxilene)--cerebrovascular disease.
    Scottish medical journal, 1978, Volume: 23, Issue:1

    Topics: Aged; Animals; Cerebrovascular Disorders; Dementia; Furans; Humans; Nafronyl

1978
New approach to treatment of recent stroke.
    British medical journal, 1979, Feb-10, Volume: 1, Issue:6160

    Topics: Cerebrovascular Disorders; Furans; Humans; Nafronyl; Research Design

1979