nafronyl has been researched along with Arterial Occlusive Diseases in 31 studies
Nafronyl: A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.
Arterial Occlusive Diseases: Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Evaluation criteria were pain assessment using a visual analogue scale, analgesic consumption considering both the power (WHO scale: level I paracetamol, level II dextropropoxyphene, level III morphine) and the dosage of the analgesic used (analgesic score), index of therapeutic success including the level of pain reduction and the absence of analgesic use." | 2.67 | [Evaluation of the analgesic effect of naftidrofuryl in permanent ischemia in patients with arterial diseases. Double-blind versus placebo study]. ( Glanddier, G; Guidicelli, H; Mosnier, M; Testart, J, 1994) |
| "Iloprost has significant (p < 0." | 2.39 | A meta-analysis of randomized placebo control trials in Fontaine stages III and IV peripheral occlusive arterial disease. ( Chalmers, TC; Dormandy, JA; Loosemore, TM, 1994) |
| " Creatinine concentration did not change following acute or chronic administration of naftidrofuryl; glomerular filtration rate and renal plasma flow were not affected by prolonged treatment (2 alpha less than 0." | 1.25 | [Effect of naftidrofuryl on creatinine serum concentration and on PAH/inulin clearance in peripheral arterial occlusive diseases]. ( Baethke, R; Beyer, KH; Heidrich, VH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (77.42) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Bourrion, B | 1 |
| Hazard, A | 1 |
| Baltazard, H | 1 |
| Sebbag, P | 1 |
| Fournier, L | 1 |
| François, M | 1 |
| Melzer, J | 1 |
| Saller, R | 1 |
| Heidrich, H | 8 |
| Maass, U | 2 |
| Amberger, HG | 1 |
| Böhme, H | 2 |
| Diehm, C | 1 |
| Dimroth, H | 1 |
| Heinrich, F | 2 |
| Hirche, H | 4 |
| Mörl, H | 2 |
| Müller-Bühl, U | 1 |
| Trübestein, G | 1 |
| Rudofsky, G | 1 |
| Kiesewetter, H | 2 |
| Jung, F | 2 |
| Weidinger, P | 1 |
| Janka, HU | 1 |
| Rinninger, F | 1 |
| Mehnert, H | 1 |
| Loosemore, TM | 1 |
| Chalmers, TC | 1 |
| Dormandy, JA | 1 |
| Testart, J | 1 |
| Guidicelli, H | 1 |
| Glanddier, G | 1 |
| Mosnier, M | 2 |
| Barradell, LB | 1 |
| Brogden, RN | 1 |
| Rolland, N | 1 |
| Lebrun, T | 1 |
| Comte, S | 1 |
| Sailly, JC | 1 |
| Frisius, H | 1 |
| Stockmann, U | 2 |
| Pohle, W | 1 |
| Barmeyer, J | 1 |
| Schümichen, C | 1 |
| Hoffmann, G | 1 |
| Schirop, T | 1 |
| Fichte, K | 1 |
| Becker, HM | 1 |
| Elert, O | 1 |
| Häring, R | 1 |
| Maurer, PC | 1 |
| Raithel, D | 1 |
| Sperling, M | 1 |
| Storz, LW | 1 |
| Rey, JL | 1 |
| Quiret, JC | 1 |
| Gamain, J | 1 |
| Errasti, M | 1 |
| Ratschow, R | 1 |
| Heidrich, VH | 1 |
| Baethke, R | 1 |
| Beyer, KH | 1 |
| Ciammaichella, A | 1 |
| Solitro, A | 1 |
| Arcuri, P | 1 |
| Blume, J | 1 |
| Bulling, B | 1 |
| Gerhards, M | 1 |
| Fellmann, N | 1 |
| Fabry, R | 1 |
| Coudert, J | 1 |
| Leonardo, G | 2 |
| Arpaia, MR | 2 |
| Del Guercio, R | 2 |
| Ranft, J | 2 |
| Abendroth, D | 1 |
| Sunder-Plassmann, L | 1 |
| Horsch, S | 1 |
| Lammersen, T | 1 |
| Pointel, JP | 1 |
| Thomas, C | 1 |
| Percebois, G | 1 |
| Debry, G | 1 |
5 reviews available for nafronyl and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Naftidrofuryl in arterial obstructive disease: A systematic revue of the literature].
Topics: Arterial Occlusive Diseases; Humans; Intermittent Claudication; Mobility Limitation; Nafronyl; Rando | 2020 |
[Clinical studies in peripheral arterial occlusive disease: update from the aspects of a meta-narrative review].
Topics: Arterial Occlusive Diseases; Cilostazol; Complementary Therapies; Humans; Intermittent Claudication; | 2013 |
[Peripheral arterial occlusions. Principles, possibilities and limits of conservative therapy].
Topics: Ancrod; Anticoagulants; Arterial Occlusive Diseases; Aspirin; Cardiomyopathies; Dextrans; Digitalis | 1981 |
A meta-analysis of randomized placebo control trials in Fontaine stages III and IV peripheral occlusive arterial disease.
Topics: Alprostadil; Amputation, Surgical; Ancrod; Arterial Occlusive Diseases; Epoprostenol; Humans; Ilopro | 1994 |
Oral naftidrofuryl. A review of its pharmacology and therapeutic use in the management of peripheral occlusive arterial disease.
Topics: Arterial Occlusive Diseases; Arteries; Half-Life; Humans; Nafronyl; Vasodilator Agents | 1996 |
10 trials available for nafronyl and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Naftidrofuryl in arterial occlusive disease. Controlled multicenter double-blind study with oral administration].
Topics: Administration, Oral; Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Bli | 1984 |
Naftidrofuryl in chronic arterial disease. Results of a controlled multicenter study.
Topics: Adult; Arterial Occlusive Diseases; Blood Flow Velocity; Blood Pressure; Chronic Disease; Clinical T | 1984 |
[Thrombocyte function in parenteral naftidrofuryl therapy].
Topics: Aged; Arterial Occlusive Diseases; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; F | 1982 |
[Evaluation of the analgesic effect of naftidrofuryl in permanent ischemia in patients with arterial diseases. Double-blind versus placebo study].
Topics: Aged; Aged, 80 and over; Analgesics; Arterial Occlusive Diseases; Double-Blind Method; Female; Human | 1994 |
[Consequences of obliterating arteriopathy of the legs on the professional activity of patients and external assistance].
Topics: Activities of Daily Living; Aged; Arterial Occlusive Diseases; Double-Blind Method; Female; Humans; | 1999 |
[Double-blind study of naftidrofuryl-hydrogen oxalate in peripheral arterial occlusive disease].
Topics: Adult; Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Double-Blind Method; Furans; Hum | 1979 |
[Influence of vasoactive substances on blood sugar and serum insulin in normal and diabetic carbohydrate metabolism (author's transl)].
Topics: Actihaemyl; Arterial Occlusive Diseases; Bencyclane; Blood Glucose; Diabetes Mellitus; Female; Gluco | 1977 |
[Effectiveness of Dusodril-Pi in arterial occlusive diseases. A multicentric double-blind study].
Topics: Arterial Occlusive Diseases; Double-Blind Method; Drug Evaluation; Femoral Artery; Furans; Humans; I | 1979 |
Calf sweat lactate in peripheral arterial occlusive disease.
Topics: Aged; Arterial Occlusive Diseases; Biomarkers; Double-Blind Method; Female; Furans; Humans; Ischemia | 1989 |
[Vasoactive drugs in peripheral arterial perfusion disorders. Problems, principles and results of the determination of therapeutic efficacy].
Topics: Arterial Occlusive Diseases; Cardiovascular Agents; Cinnarizine; Clinical Trials as Topic; Dihydroer | 1985 |
16 other studies available for nafronyl and Arterial Occlusive Diseases
| Article | Year |
|---|---|
[Current EMNID survey on peripheral arterial occlusive disease].
Topics: Arterial Occlusive Diseases; Evidence-Based Medicine; Germany; Guideline Adherence; Humans; Intermit | 2002 |
[Hemorheologic therapy in peripheral arterial occlusive disease].
Topics: Adult; Aged; Arterial Occlusive Diseases; Combined Modality Therapy; Hematocrit; Hemodilution; Human | 1984 |
[Functional results of oral dusodril therapy of obliterating arteriopathy of the lower extremities. Comparison of the angiogram, plethysmogram and Doppler ultrasound].
Topics: Angiography; Arterial Occlusive Diseases; Female; Furans; Humans; Leg; Male; Middle Aged; Nafronyl; | 1983 |
Longterm pH-measurements in the hind limb of the dog.
Topics: Animals; Arterial Occlusive Diseases; Dextrans; Dogs; Hindlimb; Hydrogen-Ion Concentration; Muscles; | 1976 |
[Status epilepticus and transient disorders of heart conduction induced by too fast intravenous infusion of naftidrofuryl].
Topics: Aged; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Electrocardiography; Electroencephalography | 1978 |
[Conservative treatment of arterial occlusive diseases with naftidrofuryl hydrogen oxalate (author's transl)].
Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Diabetes Complications; Exercise Therapy; | 1976 |
[Effect of naftidrofuryl on creatinine serum concentration and on PAH/inulin clearance in peripheral arterial occlusive diseases].
Topics: Aminohippuric Acids; Arterial Occlusive Diseases; Creatinine; Furans; Glomerular Filtration Rate; Hu | 1975 |
[Naftidrofuryl in the treatment of obstructive arterial diseases of the lower extremities].
Topics: Adolescent; Adult; Aged; Arterial Occlusive Diseases; Drug Evaluation; Furans; Humans; Male; Middle | 1975 |
Conservative drug therapy and walking exercise in stage IIb peripheral arterial occlusion disease.
Topics: Adult; Aged; Arm; Arterial Occlusive Diseases; Combined Modality Therapy; Female; Furans; Hemodiluti | 1986 |
A new method for the quantitative assessment of arterial insufficiency of the limbs: cutaneous postischemic hyperemia test by laser Doppler.
Topics: Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Blood Pressure; Female; Humans; Hype | 1987 |
[Capillary microscopic effect of naftidrofuryl in peripheral arterial occlusive disease].
Topics: Administration, Oral; Aged; Arterial Occlusive Diseases; Capillaries; Female; Furans; Humans; Inject | 1988 |
[Effect of intravenous naftidrofuryl on the microcirculation of patients in stages III and IV of arterial occlusive disease].
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Female; Furans; Humans; Infusions, Intravenous | 1988 |
[Naftidrofuryl in stages III and IV of peripheral arterial occlusive disease].
Topics: Aged; Arterial Occlusive Diseases; Blood Gas Monitoring, Transcutaneous; Drug Administration Schedul | 1988 |
Evaluation of the effects of vasoactive drugs on cutaneous microcirculation by laser Doppler velocimetry.
Topics: Adult; Aged; Arterial Occlusive Diseases; Female; Humans; Injections, Intra-Arterial; Lasers; Male; | 1986 |
[Transcutaneous measures of oxygen partial pressure and capillaroscopic parameters as affected by naftidrofuryl in patients with obliterative arteriopathies, Fontaine stages II-IV].
Topics: Aged; Aged, 80 and over; Arterial Occlusive Diseases; Capillaries; Female; Furans; Humans; Leg; Male | 1987 |
tcpO2, arterial blood flow and lactate/pyruvate modifications induced by a single dose of naftidrofuryl IV during stage III lower-limb arteriopathies.
Topics: Aged; Arterial Occlusive Diseases; Blood Gas Monitoring, Transcutaneous; Female; Furans; Humans; Lac | 1986 |