Page last updated: 2024-10-31

nafoxidine and Neoplasm Metastasis

nafoxidine has been researched along with Neoplasm Metastasis in 9 studies

Nafoxidine: An estrogen antagonist that has been used in the treatment of breast cancer.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine."7.66Clinical trial of nafoxidine in advanced breast cancer. ( De Jager, RL; Krakoff, IH; Steinbaum, FL, 1978)
"In patients with metastatic breast carcinoma, who have undergone adrenalectomy in the past, a therapeutic trial with Nafoxidine may be worthwhile particularly in patients who have demonstrable estrogen receptor in the tumor of those who have in the past shown regression of tumor after endocrine therapy."6.64Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer. ( Jain, J; Samal, B; Singhakowinta, A; Vaitkevicius, VK, 1977)
"Nafoxidine is a nonsteroidal antiestrogen available as an investigational agent from the Investigational Drug Branch of the National Cancer Institute."5.26Nafoxidine--an antiestrogen for the treatment of breast cancer. ( Carter, SK; Legha, SS; Slavik, M, 1976)
"The most useful new hormonal therapy against estrogen receptor-containing metastatic breast cancer is the development of antiestrogenic agents such as nafoxidine and tamoxifen."4.75Hormonal therapy of breast cancer: new approaches and concepts. ( Davis, HL; Legha, SS; Muggia, FM, 1978)
"Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine."3.66Clinical trial of nafoxidine in advanced breast cancer. ( De Jager, RL; Krakoff, IH; Steinbaum, FL, 1978)
"In patients with metastatic breast carcinoma, who have undergone adrenalectomy in the past, a therapeutic trial with Nafoxidine may be worthwhile particularly in patients who have demonstrable estrogen receptor in the tumor of those who have in the past shown regression of tumor after endocrine therapy."2.64Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer. ( Jain, J; Samal, B; Singhakowinta, A; Vaitkevicius, VK, 1977)
"Nafoxidine is a nonsteroidal antiestrogen available as an investigational agent from the Investigational Drug Branch of the National Cancer Institute."1.26Nafoxidine--an antiestrogen for the treatment of breast cancer. ( Carter, SK; Legha, SS; Slavik, M, 1976)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Myers, AM1
Moore, GE1
Major, FJ1
Stoll, BA1
Tagnon, HJ1
Jain, J1
Samal, B1
Singhakowinta, A2
Vaitkevicius, VK2
Legha, SS2
Davis, HL1
Muggia, FM1
Feun, LG1
Drelichman, A1
Oishi, N1
Steinbaum, FL1
De Jager, RL1
Krakoff, IH1
Slavik, M1
Carter, SK1
Sasaki, GH1
Leung, BS1
Fletcher, WS1

Reviews

2 reviews available for nafoxidine and Neoplasm Metastasis

ArticleYear
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977
Hormonal therapy of breast cancer: new approaches and concepts.
    Annals of internal medicine, 1978, Volume: 88, Issue:1

    Topics: Adrenalectomy; Breast Neoplasms; Castration; Clomiphene; Ergotamines; Estrogen Antagonists; Female;

1978

Trials

3 trials available for nafoxidine and Neoplasm Metastasis

ArticleYear
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977
Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer.
    Cancer, 1977, Volume: 40, Issue:5

    Topics: Adrenalectomy; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; F

1977
Phase II study of nafoxidine in the therapy for advanced renal carcinoma.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Kidney Neopl

1979

Other Studies

5 other studies available for nafoxidine and Neoplasm Metastasis

ArticleYear
Advanced ovarian carcinoma: response to antiestrogen therapy.
    Cancer, 1981, Dec-01, Volume: 48, Issue:11

    Topics: Adult; Cystadenocarcinoma; Estrogen Antagonists; Female; Humans; Megestrol; Middle Aged; Nafoxidine;

1981
Clinical experience with tamoxifen in advanced breast cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 71

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Clomiphene; Drug Tolerance; Female; Humans; Hypercalcemi

1980
Clinical trial of nafoxidine in advanced breast cancer.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Mid

1978
Nafoxidine--an antiestrogen for the treatment of breast cancer.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Animals; Breast Neoplasms; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Ichthyosis

1976
Therapeutic value of nafoxidine hydrochloride in the treatment of advanced carcinoma of the human breast.
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:4

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Midd

1976