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nafoxidine and Breast Neoplasms

nafoxidine has been researched along with Breast Neoplasms in 59 studies

Nafoxidine: An estrogen antagonist that has been used in the treatment of breast cancer.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"A randomized clinical trial of nafoxidine, a non-steroidal oestrogen antagonist, and ethinyloestradiol in postmenopausal patients with advanced breast cancer produced objective remissions in 31% of 49 women receiving nafoxidine and in 14% of 49 receiving ethinyloestradiol."9.04Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study. ( Blonk-Van Der Wijst, J; Drochmans, A; Engelsman, E; Gorins, A; Heuson, JC; Maass, H; Michel, J; Nowakowski, H, 1975)
"Effects of tamoxifen (TAM), nafoxidine (NFA), 4-hydroxytamoxifen (4-OH-TAM), 3-hydroxytamoxifen (3-OH-TAM), and medroxyprogesterone acetate (MPA) on the clonogenic growth of a hormone-responsive human breast cancer cell line (MCF-7) and its tamoxifen-resistant variant (R-27) were studied."7.67[Effects of antiestrogens and medroxyprogesterone acetate on the clonogenic growth of tamoxifen-sensitive and resistant human breast cancer cells]. ( Nomura, Y; Takaeko, F; Tashiro, H, 1985)
"Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine."7.66Clinical trial of nafoxidine in advanced breast cancer. ( De Jager, RL; Krakoff, IH; Steinbaum, FL, 1978)
"The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of whom the disease had become resistant to, or relapsed after, previous endocrine treatment."7.65Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases. ( Bloom, HJ; Boesen, E, 1974)
"In patients with metastatic breast carcinoma, who have undergone adrenalectomy in the past, a therapeutic trial with Nafoxidine may be worthwhile particularly in patients who have demonstrable estrogen receptor in the tumor of those who have in the past shown regression of tumor after endocrine therapy."6.64Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer. ( Jain, J; Samal, B; Singhakowinta, A; Vaitkevicius, VK, 1977)
"Nafoxidine is a nonsteroidal antiestrogen available as an investigational agent from the Investigational Drug Branch of the National Cancer Institute."5.26Nafoxidine--an antiestrogen for the treatment of breast cancer. ( Carter, SK; Legha, SS; Slavik, M, 1976)
"A randomized clinical trial of nafoxidine, a non-steroidal oestrogen antagonist, and ethinyloestradiol in postmenopausal patients with advanced breast cancer produced objective remissions in 31% of 49 women receiving nafoxidine and in 14% of 49 receiving ethinyloestradiol."5.04Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study. ( Blonk-Van Der Wijst, J; Drochmans, A; Engelsman, E; Gorins, A; Heuson, JC; Maass, H; Michel, J; Nowakowski, H, 1975)
"The most useful new hormonal therapy against estrogen receptor-containing metastatic breast cancer is the development of antiestrogenic agents such as nafoxidine and tamoxifen."4.75Hormonal therapy of breast cancer: new approaches and concepts. ( Davis, HL; Legha, SS; Muggia, FM, 1978)
"The effects of estradiol and antiestrogens on two estrogen-regulated proteins (52 and 160 kDa) and an estrogen-inducible mRNA (pS2) have been measured in the MCF7 human breast cancer cell line and two tamoxifen-resistant sublines."3.67Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines. ( Brown, AM; Chambon, P; Krust, A; Lippman, ME; May, FE; Rochefort, H; Westley, B, 1984)
"Effects of tamoxifen (TAM), nafoxidine (NFA), 4-hydroxytamoxifen (4-OH-TAM), 3-hydroxytamoxifen (3-OH-TAM), and medroxyprogesterone acetate (MPA) on the clonogenic growth of a hormone-responsive human breast cancer cell line (MCF-7) and its tamoxifen-resistant variant (R-27) were studied."3.67[Effects of antiestrogens and medroxyprogesterone acetate on the clonogenic growth of tamoxifen-sensitive and resistant human breast cancer cells]. ( Nomura, Y; Takaeko, F; Tashiro, H, 1985)
"Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine."3.66Clinical trial of nafoxidine in advanced breast cancer. ( De Jager, RL; Krakoff, IH; Steinbaum, FL, 1978)
"Human breast cancer was studied by in vitro techniques on tissue slices and extracts for a specific binding of estradiol and dihydrotestosterone."3.65Steroid hormone receptors in human breast cancer and clinical correlations. ( Engel, B; Maass, H; Nowakowski, H; Stolzenbach, G; Trams, G, 1975)
", nafoxidine, tamoxifen, and clomiphene, have been reported to induce objective clinical remissions in patients with breast cancer."3.65Letter: Antiestrogens in the treatment of cancer. ( Legha, S; Muggia, FM, 1976)
"The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of whom the disease had become resistant to, or relapsed after, previous endocrine treatment."3.65Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases. ( Bloom, HJ; Boesen, E, 1974)
"In patients with metastatic breast carcinoma, who have undergone adrenalectomy in the past, a therapeutic trial with Nafoxidine may be worthwhile particularly in patients who have demonstrable estrogen receptor in the tumor of those who have in the past shown regression of tumor after endocrine therapy."2.64Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer. ( Jain, J; Samal, B; Singhakowinta, A; Vaitkevicius, VK, 1977)
"In T47D breast cancer cells, the NBD-progestin showed receptor-mediated uptake and nuclear localization."1.28Receptor binding of NBD-labeled fluorescent estrogens and progestins in whole cells and cell-free preparations. ( Carlson, KE; Coppey, M; Katzenellenbogen, JA; Magdelenat, H, 1989)
"In human breast cancer the proliferating cells appear to differ from those containing estrogen receptors (ER) as shown by studies on isolated cellular subpopulations."1.27In vitro analysis of the cellular proliferative response to 17-beta-estradiol of human breast cancer. ( Bover, L; Bravo, AI; Dain, L; Guman, N; Mordoh, J; Podhajcer, OL, 1988)
"Patients with advanced breast cancer may develop acute, severe hypercalcemia when treated with estrogens or antiestrogens."1.27Estrogens and antiestrogens stimulate release of bone resorbing activity by cultured human breast cancer cells. ( Eilon, G; Mundy, GR; Saez, S; Valentin-Opran, A, 1985)
"We describe studies with T47D human breast cancer cells, whose PRs are not regulated by estradiol, though present in extraordinary amounts (300,000 sites per cell)."1.26Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance. ( Horwitz, KB; Lessey, BA; Mockus, MB, 1982)
"The human breast cancer cell line MCF-7 does not require estrogen for growth, but paradoxically its growth is inhibited by antiestrogens."1.26Human breast cancer: biologically active estrogen receptor in the absence of estrogen? ( Chamness, GC; Horwitz, KB; McGuire, WL; Zava, DT, 1977)
"We have used human breast cancer cells in long term culture as an in vitro model to study the roles of estradiol and the antiestrogens, tamoxifen and nafoxidine, on cell growth and progesterone receptor (PgR) induction."1.26Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. ( Horwitz, KB; Koseki, Y; McGuire, WL, 1978)
"Nafoxidine is a nonsteroidal antiestrogen available as an investigational agent from the Investigational Drug Branch of the National Cancer Institute."1.26Nafoxidine--an antiestrogen for the treatment of breast cancer. ( Carter, SK; Legha, SS; Slavik, M, 1976)
"The presence of estrogen receptors in human mammary carcinomas has a distinct correlation with the response to adrenalectomy."1.25Human breast cancer and estrogen receptor. ( Cleton, FJ; Engelsman, E; Korsten, CB; Persijn, JP, 1973)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199056 (94.92)18.7374
1990's3 (5.08)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosati, RL1
Da Silva Jardine, P1
Cameron, KO1
Thompson, DD1
Ke, HZ1
Toler, SM1
Brown, TA1
Pan, LC1
Ebbinghaus, CF1
Reinhold, AR1
Elliott, NC1
Newhouse, BN1
Tjoa, CM1
Sweetnam, PM1
Cole, MJ1
Arriola, MW1
Gauthier, JW1
Crawford, DT1
Nickerson, DF1
Pirie, CM1
Qi, H1
Simmons, HA1
Tkalcevic, GT1
van Marle, J1
Lindeman, J1
Ariens, AT1
Labruyère, W1
van Weeren-Kramer, J1
Westley, B1
May, FE1
Brown, AM1
Krust, A1
Chambon, P1
Lippman, ME2
Rochefort, H1
Eckert, RL1
Mullick, A1
Rorke, EA1
Katzenellenbogen, BS1
Osborne, CK1
Boldt, DH1
Estrada, P1
Adams, DJ3
Hajj, H1
Edwards, DP4
Bjercke, RJ1
McGuire, WL11
Horwitz, KB7
Syne, JS1
Markaverich, BM1
Clark, JH1
Panko, WB1
Aiginger, P1
Kuttenn, F1
Mockus, MB1
Lessey, BA1
Stoll, BA2
Murthy, SR1
Savage, N1
Strobl, JS1
Monaco, ME1
Brooks, SC1
Saunders, DE1
Singhakowinta, A2
Vaitkevicius, VK2
Wiseman, H1
Halliwell, B1
Poortman, J1
Prenen, JA1
Schwarz, F1
Thijssen, JH1
Bolt, HM1
Braunsberg, H1
Carbone, PP1
Maass, H3
Engel, B1
Nowakowski, H3
Stolzenbach, G1
Trams, G1
Görlich, M2
Heise, E2
Zava, DT3
Chamness, GC2
Tagnon, HJ1
Jain, J1
Samal, B1
Legha, SS3
Davis, HL1
Muggia, FM2
Számel, I1
Kerpel-Fronius, S1
Mulder, J1
Verhaar, MA1
McIntosh, IH1
Thynne, GS1
Metz, R1
Bey, P1
Moseson, DL1
Sasaki, GH2
Kraybill, WG1
Leung, BS2
Davenport, CE1
Fletcher, WS2
Steinbaum, FL1
De Jager, RL1
Krakoff, IH1
Burke, RE1
Mira, JG1
Datta, R1
Garola, RE1
Koseki, Y1
Heuson, JC4
Longeval, E1
Mattheiem, WH1
Deboel, MC1
Sylvester, RJ1
Leclercq, G1
Legha, S1
Slavik, M1
Carter, SK2
Engelsman, E5
Blonk-Van Der Wijst, J1
Drochmans, A2
Michel, J1
Gorins, A2
Blonk Van Der Wijst, J1
Cheix, F1
Sobrinho, LG1
Eskenazi, F1
Lopes, MC1
Tavares, MC1
Vale, MG1
Carvalho, AP1
Carlson, KE1
Coppey, M1
Magdelenat, H1
Katzenellenbogen, JA1
Kida, N1
Yoshimura, T1
Mori, K1
Hayashi, K1
Nomura, Y1
Tashiro, H1
Takaeko, F1
Podhajcer, OL1
Bravo, AI1
Dain, L1
Guman, N1
Bover, L1
Mordoh, J1
Valentin-Opran, A1
Eilon, G1
Saez, S1
Mundy, GR1
Santa Cruz, AR1
Medrano, EE1
Baldi, A1
Korsten, CB2
Persijn, JP2
Cleton, FJ2
Bloom, HJ1
Boesen, E1
L'Hermite, M1
Robyn, C1
Rozencweig, M1

Reviews

3 reviews available for nafoxidine and Breast Neoplasms

ArticleYear
Studies on mechanisms of estrogen and antiestrogen action in human breast cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 71

    Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Dactinomycin; Dose-Response Relationship, Drug

1980
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977
Hormonal therapy of breast cancer: new approaches and concepts.
    Annals of internal medicine, 1978, Volume: 88, Issue:1

    Topics: Adrenalectomy; Breast Neoplasms; Castration; Clomiphene; Ergotamines; Estrogen Antagonists; Female;

1978

Trials

5 trials available for nafoxidine and Breast Neoplasms

ArticleYear
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977
Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer.
    Cancer, 1977, Volume: 40, Issue:5

    Topics: Adrenalectomy; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; F

1977
Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study.
    British medical journal, 1975, Jun-28, Volume: 2, Issue:5973

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Ethinyl Estradiol; Fe

1975
Controlled clinical trial of L-dopa and nafoxidine in advanced breast cancer: an E.O.R.T.C. study.
    British medical journal, 1975, Jun-28, Volume: 2, Issue:5973

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Levod

1975
Letter: Breast cancer regression under oestrogen therapy.
    British medical journal, 1974, Mar-02, Volume: 1, Issue:5904

    Topics: Aged; Breast Neoplasms; Estrogens; Ethinyl Estradiol; Female; Humans; Menopause; Middle Aged; Nafoxi

1974

Other Studies

52 other studies available for nafoxidine and Breast Neoplasms

ArticleYear
Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene.
    Journal of medicinal chemistry, 1998, Jul-30, Volume: 41, Issue:16

    Topics: Administration, Oral; Animals; Biological Availability; Bone Density; Breast Neoplasms; Cell Divisio

1998
Estrogen receptors in human breast cancer. I. Specificity of the histochemical localization of estrogen receptors using an estrogen-albumin FITC complex.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1982, Volume: 40, Issue:1

    Topics: Animals; Breast Neoplasms; Cattle; Cell Transformation, Neoplastic; Estrogens; Fluorescein-5-isothio

1982
Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines.
    The Journal of biological chemistry, 1984, Aug-25, Volume: 259, Issue:16

    Topics: Breast Neoplasms; Cell Line; Drug Resistance; Estradiol; Estrogen Antagonists; Female; Humans; Kinet

1984
Estrogen receptor synthesis and turnover in MCF-7 breast cancer cells measured by a density shift technique.
    Endocrinology, 1984, Volume: 114, Issue:2

    Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytosol; Female; Humans

1984
Human breast cancer cell cycle synchronization by estrogens and antiestrogens in culture.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Breast Neoplasms; Cell Cycle; Cell Line; Culture Media; Estradiol; Estrogen Antagonists; Female; Hum

1984
Detection of a Mr 24,000 estrogen-regulated protein in human breast cancer by monoclonal antibodies.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Biopsy; Breast Neoplasms; Cell Line; Elec

1983
Estrogen binding sites in the nucleus of normal and malignant human tissue: characteristics of the multiple nuclear binding sites.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Breast Neoplasms; Cell Nucleus; Cytosol; DNA, Neoplasm; Estradiol; Female; Humans; Kinetics; Myometr

1982
Nuclear estrogen receptor release from antiestrogen suppression: amplified induction of progesterone receptor in MCF-7 human breast cancer cells.
    Endocrinology, 1981, Volume: 108, Issue:5

    Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Dactinomycin; Estradiol; Female; Humans; Kinetics; Nafoxi

1981
Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.
    Cell, 1982, Volume: 28, Issue:3

    Topics: Breast Neoplasms; Bromodeoxyuridine; Butyrates; Cell Nucleus; Cells, Cultured; Cycloheximide; Cytopl

1982
Estrogen regulation of specific messinger RNA's in human breast cancer cells.
    Biochemical and biophysical research communications, 1980, Dec-31, Volume: 97, Issue:4

    Topics: Breast Neoplasms; Cell Line; Estradiol; Female; Humans; Molecular Weight; Nafoxidine; Neoplasm Prote

1980
Clinical experience with tamoxifen in advanced breast cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 71

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Clomiphene; Drug Tolerance; Female; Humans; Hypercalcemi

1980
Effects of estrogen and antiestrogen on DNA polymerase in human breast cancer.
    Cancer research, 1980, Volume: 40, Issue:5

    Topics: Breast Neoplasms; Cell Division; Cell Line; DNA-Directed DNA Polymerase; Dose-Response Relationship,

1980
Estrogen induced synthesis of specific proteins in human breast cancer cells.
    Biochemical and biophysical research communications, 1980, Apr-14, Volume: 93, Issue:3

    Topics: Breast Neoplasms; Carbon Radioisotopes; Cell Line; Estradiol; Female; Humans; Kinetics; Leucine; Naf

1980
The role of intracellular equilibria and the effect of antiestrogens on estrogen-receptor dissociation kinetics from perfused cultures of human breast cancer cells.
    Endocrinology, 1980, Volume: 107, Issue:2

    Topics: Binding Sites; Breast Neoplasms; Cell Line; Clomiphene; Estradiol; Estriol; Female; Humans; Kinetics

1980
Relation of tumor content of estrogen and progesterone receptors with response of patient to endocrine therapy.
    Cancer, 1980, Dec-15, Volume: 46, Issue:12 Suppl

    Topics: Breast Neoplasms; Diethylstilbestrol; Estrogen Antagonists; Female; Humans; Nafoxidine; Neoplasms, H

1980
Tamoxifen and related compounds protect against lipid peroxidation in isolated nuclei: relevance to the potential anticarcinogenic benefits of breast cancer prevention and therapy with tamoxifen?
    Free radical biology & medicine, 1994, Volume: 17, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Nucleus; Estradiol; Estrogen Antagonists; F

1994
Interaction of delta-5-androstene-3beta, 17beta-diol with estradiol and dihydrotestosterone receptors in human myometrial and mammary cancer tissue.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:3

    Topics: Adult; Aged; Androstenediols; Androstenedione; Binding, Competitive; Breast Neoplasms; Cyproterone;

1975
[The importance of estrogen receptors in the pharmacotherapy of mammary carcinoma (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Feb-28, Volume: 117, Issue:9

    Topics: Androgens; Breast Neoplasms; Castration; Cytoplasm; Estrogen Antagonists; Estrogens; Female; Humans;

1975
Factors influencing the estimation of oestrogen receptors in human malignant breast tumours.
    European journal of cancer, 1975, Volume: 11, Issue:7

    Topics: Breast Neoplasms; Cytosol; Estradiol; Freezing; Humans; Nafoxidine; Nitromifene; Receptors, Cell Sur

1975
Editorial: Antiestrogens and breast cancer treatment.
    Annals of internal medicine, 1975, Volume: 83, Issue:5

    Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Nafoxidine; Receptors, Cell Surface; Tamoxif

1975
Steroid hormone receptors in human breast cancer and clinical correlations.
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Castration; Dihydrotestosterone; Estradiol; Female; Humans; Menopause

1975
Estradiol receptor activity in tissues of human breast cancer.
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5

    Topics: Androstanols; Breast Neoplasms; Estradiol; Female; Humans; Lymph Nodes; Menopause; Nafoxidine; Progn

1975
Human breast cancer: biologically active estrogen receptor in the absence of estrogen?
    Science (New York, N.Y.), 1977, May-06, Volume: 196, Issue:4290

    Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Cytoplasm; Estradiol; Nafoxidine; Neoplasm

1977
Chemotherapeutic agents and estradiol receptor binding capacity.
    Oncology, 1979, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Dianhydrogalactitol; Estradiol; Female;

1979
Estrogen control of progesterone receptor induction in human breast cancer: role of nuclear estrogen receptor.
    Advances in experimental medicine and biology, 1979, Volume: 117

    Topics: Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Estradiol; Female; Humans; Nafoxidine; Recepto

1979
A comparative study on estradiol receptor assays in human breast cancer tissue.
    Clinica chimica acta; international journal of clinical chemistry, 1979, Dec-03, Volume: 99, Issue:2

    Topics: Binding, Competitive; Breast Neoplasms; Cytosol; Estradiol; Female; Humans; Kinetics; Nafoxidine; Re

1979
Tumour stimulation by anti-oestrogens.
    The British journal of surgery, 1977, Volume: 64, Issue:12

    Topics: Adult; Breast Neoplasms; Female; Humans; Middle Aged; Nafoxidine; Pyrrolidines; Recurrence; Tamoxife

1977
[Treatment of breast cancers with antiestrogens. Clinical study of nafoxidine].
    La Nouvelle presse medicale, 1977, Dec-24, Volume: 6, Issue:44

    Topics: Breast Neoplasms; Female; Humans; Nafoxidine; Pyrrolidines

1977
The use of antiestrogens tamoxifen and nafoxidine in the treatment of human breast cancer in correlation with estrogen receptor values. A phase II study.
    Cancer, 1978, Volume: 41, Issue:3

    Topics: Breast Neoplasms; Female; Humans; Nafoxidine; Pyrrolidines; Receptors, Estrogen; Tamoxifen

1978
Clinical trial of nafoxidine in advanced breast cancer.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Mid

1978
Estrogen action following irradiation of human breast cancer cells.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Line; Estradiol; Gamma Rays; Humans; Nafoxidine; Neoplasms, E

1978
Receptors and breast cancer: do we know it all?
    Journal of steroid biochemistry, 1978, Volume: 9, Issue:5

    Topics: Breast Neoplasms; Cell Nucleus; Cells, Cultured; Cytosol; Dihydrotestosterone; Estradiol; Female; Hu

1978
Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen.
    Endocrinology, 1978, Volume: 103, Issue:5

    Topics: Breast Neoplasms; Cells, Cultured; Estradiol; Estrogen Antagonists; Humans; Nafoxidine; Receptors, P

1978
Significance of quantitative assessment of estrogen receptors for endocrine therapy in advanced breast cancer.
    Cancer, 1977, Volume: 39, Issue:5

    Topics: Adrenalectomy; Adult; Aged; Androgens; Breast Neoplasms; Castration; Ethinyl Estradiol; Female; Huma

1977
Letter: Antiestrogens in the treatment of cancer.
    Annals of internal medicine, 1976, Volume: 84, Issue:6

    Topics: Breast Neoplasms; Clomiphene; Estrogen Antagonists; Female; Hormone Antagonists; Humans; Male; Nafox

1976
Nafoxidine--an antiestrogen for the treatment of breast cancer.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Animals; Breast Neoplasms; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Ichthyosis

1976
Antiestrogens in the treatment of breast cancer.
    Cancer treatment reviews, 1976, Volume: 3, Issue:4

    Topics: Breast Neoplasms; Clomiphene; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Humans

1976
[Further aspects of hormone therapy of metastatic breast cancer].
    Semaine des hopitaux. Therapeutique, 1975, Volume: 51, Issue:1

    Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Nafoxidine; Prolactin; Pyrrolidines; Stilben

1975
Therapeutic value of nafoxidine hydrochloride in the treatment of advanced carcinoma of the human breast.
    Surgery, gynecology & obstetrics, 1976, Volume: 142, Issue:4

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Midd

1976
Characterization of estrogen and antiestrogen binding to the cytosol and microsomes of breast tumors.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:3

    Topics: Binding, Competitive; Breast Neoplasms; Clomiphene; Cytosol; Enclomiphene; Estrogen Antagonists; Est

1991
Receptor binding of NBD-labeled fluorescent estrogens and progestins in whole cells and cell-free preparations.
    Journal of steroid biochemistry, 1989, Volume: 32, Issue:3

    Topics: Affinity Labels; Binding, Competitive; Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Estradi

1989
Hormonal regulation of synthesis and secretion of pS2 protein relevant to growth of human breast cancer cells (MCF-7).
    Cancer research, 1989, Jul-01, Volume: 49, Issue:13

    Topics: Androgens; Breast Neoplasms; Cell Division; Cycloheximide; Dactinomycin; DNA, Neoplasm; Estrogens; H

1989
[Effects of antiestrogens and medroxyprogesterone acetate on the clonogenic growth of tamoxifen-sensitive and resistant human breast cancer cells].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:4

    Topics: Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; Drug Resistance; Estrogen Antagonists;

1985
In vitro analysis of the cellular proliferative response to 17-beta-estradiol of human breast cancer.
    Cancer, 1988, May-01, Volume: 61, Issue:9

    Topics: Breast Neoplasms; Carcinoembryonic Antigen; Cell Division; Diethylstilbestrol; DNA Replication; DNA,

1988
Estrogens and antiestrogens stimulate release of bone resorbing activity by cultured human breast cancer cells.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Biological Products; Bone Resorption; Breast Neoplasms; Cells, Cultured; Cytokines; Dinoprostone; Es

1985
Dolichol-sugar derivative synthesis in human breast cancer cell line (T47D). Effects of estrogens and antiestrogens.
    Biochemical and biophysical research communications, 1985, Jan-16, Volume: 126, Issue:1

    Topics: Breast Neoplasms; Cell Line; Chromatography, Ion Exchange; Chromatography, Thin Layer; Estradiol; Fe

1985
Letter: Anti-oestrogens and breast cancer.
    Lancet (London, England), 1974, Jul-20, Volume: 2, Issue:7873

    Topics: Biopsy; Breast Neoplasms; Estrogen Antagonists; Female; Humans; Nafoxidine; Pyrrolidines; Remission,

1974
Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases.
    British medical journal, 1974, Apr-06, Volume: 2, Issue:5909

    Topics: Adult; Aged; Breast Neoplasms; Cataract; Estrogen Antagonists; Female; Humans; Hypophysectomy; Menop

1974
Antioestrogens in treatment of breast cancer.
    British medical journal, 1974, Jun-01, Volume: 2, Issue:5917

    Topics: Antineoplastic Agents; Breast Neoplasms; Dimethylamines; Estrogen Antagonists; Female; Humans; Menop

1974
Proceedings: Clinical value of predictive tests for advanced breast cancer.
    British journal of cancer, 1974, Volume: 30, Issue:2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Androgens; Breast Neoplasms; Castration; Estradiol; Estrogen

1974
Human breast cancer and estrogen receptor.
    Archivum chirurgicum Neerlandicum, 1973, Volume: 25, Issue:4

    Topics: Adrenalectomy; Breast Neoplasms; Castration; Estrogens; Ethinyl Estradiol; Female; Humans; Hypophyse

1973
Letter: Antioestrogens in treatment of breast cancer.
    British medical journal, 1974, May-25, Volume: 2, Issue:5916

    Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Menopause; Nafoxidine; Pyrrolidines

1974