Page last updated: 2024-10-31

nafamostat and Thrombosis

nafamostat has been researched along with Thrombosis in 14 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" The objectives of this retrospective study were to assess the effect of nafamostat on circuit patency of CRRT and the safety regarding bleeding complications in patients at high risk of bleeding."7.78The role of nafamostat mesylate in continuous renal replacement therapy among patients at high risk of bleeding. ( Baek, NN; Huh, W; Jang, HR; Kim, DJ; Kim, YG; Lee, JE; Oh, HY, 2012)
" However, patients with bleeding risk and/or heparin-related side effects may necessitate alternative strategies: among these, nafamostat mesilate (NM) has been reported."5.22Use of nafamostat mesilate for anticoagulation during extracorporeal membrane oxygenation: A systematic review. ( Astuto, M; Brancati, S; CurrĂ², JM; Dezio, V; La Via, L; Martucci, G; Murabito, P; Pappalardo, F; Sanfilippo, F, 2022)
" The objectives of this retrospective study were to assess the effect of nafamostat on circuit patency of CRRT and the safety regarding bleeding complications in patients at high risk of bleeding."3.78The role of nafamostat mesylate in continuous renal replacement therapy among patients at high risk of bleeding. ( Baek, NN; Huh, W; Jang, HR; Kim, DJ; Kim, YG; Lee, JE; Oh, HY, 2012)
"Nafamostat mesilate provided sufficient filter survival without causing major bleeding complications despite the prolongation of APTT."3.77Nafamostat mesilate as an anticoagulant during continuous veno-venous hemodialysis: a three-year retrospective cohort study. ( Hosoya, T; Maruyama, Y; Takinami, M; Uchino, S; Yamamoto, H; Yokoyama, K; Yoshida, H, 2011)
"Multiple hemorrhagic cerebral infarctions were recognized on a computed tomographic (CT) scan."1.39Left atrium ball thrombus in a patient with hemorrhagic cerebral infarction. ( Machida, D; Masuda, M; Matsuki, Y; Okamoto, H; Tokunaga, S; Yasuda, S, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's4 (28.57)18.2507
2000's5 (35.71)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Sanfilippo, F1
CurrĂ², JM1
La Via, L1
Dezio, V1
Martucci, G1
Brancati, S1
Murabito, P1
Pappalardo, F1
Astuto, M1
Yasuda, S1
Tokunaga, S1
Matsuki, Y1
Okamoto, H1
Machida, D1
Masuda, M2
Maruyama, Y1
Yoshida, H1
Uchino, S1
Yokoyama, K1
Yamamoto, H1
Takinami, M1
Hosoya, T1
Baek, NN1
Jang, HR1
Huh, W1
Kim, YG1
Kim, DJ1
Oh, HY1
Lee, JE1
Sekido, H1
Matsuo, K1
Takeda, K1
Morioka, D1
Kubota, T2
Tanaka, K3
Endo, I1
Togo, S1
Shimada, H1
Kaminishi, Y1
Hiramatsu, Y1
Watanabe, Y1
Yoshimura, Y1
Sakakibara, Y1
Sawaki, D1
Otani, Y1
Kobayakawa, N1
Sekita, G1
Fukushima, K1
Takeuchi, H1
Ogawa, T1
Takemura, T1
Aoyagi, T1
Borawski, J1
Takano, H1
Miyamoto, Y1
Kaneko, M1
Matsuwaka, R1
Kuratani, T1
Amemiya, A1
Nakano, S1
Matsuda, H1
Morishita, K1
Inoue, S1
Baba, T1
Sakata, J1
Kazui, T1
Abe, T1
Isogai, E1
Isogai, H1
Kimura, K1
Hayashi, S1
Fujii, N1
Takeshi, K1
Sato, T1
Kondo, C1
Yada, I1
Yuasa, H1
Kusagawa, M1
Nasu, M1
Okada, Y1
Shomura, T1
Matsuo, T1
Matsuo, M1
Ouga-Maruyama, S1
Fukamachi, K1
Matsuzaki, K1
Asou, T1
Toshima, Y1
Kinoshita, K1
Mayumi, H1
Tominaga, R1
Miyamoto, K1
Komori, M1

Reviews

2 reviews available for nafamostat and Thrombosis

ArticleYear
Use of nafamostat mesilate for anticoagulation during extracorporeal membrane oxygenation: A systematic review.
    Artificial organs, 2022, Volume: 46, Issue:12

    Topics: Anticoagulants; Extracorporeal Membrane Oxygenation; Hemorrhage; Heparin; Humans; Retrospective Stud

2022
Myeloperoxidase as a marker of hemodialysis biocompatibility and oxidative stress: the underestimated modifying effects of heparin.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Anticoagulants; Atherosclerosis; Benzamidines; Biocompatible Materials; Biomarkers; Blood Vessels; E

2006

Trials

2 trials available for nafamostat and Thrombosis

ArticleYear
Effects of nafamostat mesilate and minimal-dose aprotinin on blood-foreign surface interactions in cardiopulmonary bypass.
    The Annals of thoracic surgery, 2004, Volume: 77, Issue:2

    Topics: Aged; Aprotinin; Benzamidines; Cardiopulmonary Bypass; Dose-Response Relationship, Drug; Drug Therap

2004
Our distal aortic perfusion system in descending thoracic and thoracoabdominal aortic aneurysm repairs.
    Artificial organs, 1997, Volume: 21, Issue:7

    Topics: Analysis of Variance; Anticoagulants; Antithrombins; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Th

1997

Other Studies

10 other studies available for nafamostat and Thrombosis

ArticleYear
Left atrium ball thrombus in a patient with hemorrhagic cerebral infarction.
    The Annals of thoracic surgery, 2013, Volume: 96, Issue:6

    Topics: Aged; Anticoagulants; Benzamidines; Cardiac Surgical Procedures; Cerebral Hemorrhage; Cerebral Infar

2013
Nafamostat mesilate as an anticoagulant during continuous veno-venous hemodialysis: a three-year retrospective cohort study.
    The International journal of artificial organs, 2011, Volume: 34, Issue:7

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Analysis of Variance; Anticoagulants; Benzamidines; Cr

2011
The role of nafamostat mesylate in continuous renal replacement therapy among patients at high risk of bleeding.
    Renal failure, 2012, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Anticoagulants; Benzamidines; Female; Fibrinolysin; Follow-Up Studies; Guanidin

2012
Successful adult ABO-incompatible liver transplantation: therapeutic strategy for thrombotic microangiopathy is the key to success.
    Transplantation, 2003, May-15, Volume: 75, Issue:9

    Topics: ABO Blood-Group System; Benzamidines; Blood Group Incompatibility; Female; Guanidines; Humans; Liver

2003
A case of heparin-induced thrombocytopenia with sepsis and congestive heart failure--first autopsy report on Japan--.
    Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:12

    Topics: Aged; Aged, 80 and over; Antibodies; Benzamidines; Enzyme-Linked Immunosorbent Assay; Fatal Outcome;

2004
[Experimental study on heparin-free cardiopulmonary bypass using nafamostat mesilate (FUT-175) and heparin-coated circuit].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1993, Volume: 41, Issue:11

    Topics: Animals; Benzamidines; Blood Coagulation Tests; Cardiopulmonary Bypass; Guanidines; Heparin; Platele

1993
Role of tumor necrosis factor alpha in gnotobiotic mice infected with an Escherichia coli O157:H7 strain.
    Infection and immunity, 1998, Volume: 66, Issue:1

    Topics: Animals; Bacterial Toxins; Benzamidines; Brain; Colon; Colony Count, Microbial; Edema; Escherichia c

1998
Hematological problems during the use of cardiac assist devices: clinical experiences in Japan.
    Artificial organs, 1992, Volume: 16, Issue:2

    Topics: Aged; Anticoagulants; Antithrombin III; Benzamidines; Blood Coagulation; Female; Fibrinopeptide A; G

1992
Can nafamostat mesilate be used for temporary management of hemodialysis in a patient with heparin-induced thrombocytopenia (HIT)?
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:4

    Topics: Anticoagulants; Benzamidines; Guanidines; Heparin; Humans; Male; Middle Aged; Platelet Activation; P

2001
[Clinical assessment of anticoagulation therapy during left ventricular assist with artificial heart: induction with protease inhibitor].
    Kyobu geka. The Japanese journal of thoracic surgery, 1989, Volume: 42, Issue:6

    Topics: Aged; Assisted Circulation; Benzamidines; Drug Evaluation; Drug Therapy, Combination; Gabexate; Guan

1989