nafamostat has been researched along with Shock in 9 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "and 25 mg/kg p." | 1.26 | Inhibition of various immunological reactions in vivo by a new synthetic complement inhibitor. ( Fujii, S; Hitomi, Y, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rathore, AP | 1 |
| Mantri, CK | 1 |
| Aman, SA | 1 |
| Syenina, A | 1 |
| Ooi, J | 1 |
| Jagaraj, CJ | 1 |
| Goh, CC | 1 |
| Tissera, H | 1 |
| Wilder-Smith, A | 1 |
| Ng, LG | 1 |
| Gubler, DJ | 1 |
| St John, AL | 1 |
| Ishimaru, K | 1 |
| Mitsuoka, H | 2 |
| Unno, N | 1 |
| Inuzuka, K | 1 |
| Nakamura, S | 1 |
| Schmid-Schönbein, GW | 4 |
| Hitomi, Y | 1 |
| Fujii, S | 1 |
| Miyazaki, M | 1 |
| Yoda, K | 1 |
| Ogli, K | 1 |
| Yokono, S | 1 |
| Kistler, EB | 3 |
| Ueda, N | 1 |
| Midorikawa, A | 1 |
| Ino, Y | 1 |
| Oda, M | 1 |
| Nakamura, K | 1 |
| Suzuki, S | 1 |
| Kurumi, M | 1 |
| Hugli, TE | 2 |
| Lefer, AM | 1 |
| Kashima, K | 1 |
| Kataoka, K | 1 |
| Umehara, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue Patients: a Multicenter Randomized, Double-blind, Placebo Controlled, Superiority Trial[NCT04673422] | Phase 2/Phase 3 | 358 participants (Actual) | Interventional | 2021-01-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for nafamostat and Shock
| Article | Year |
|---|---|
Dengue virus-elicited tryptase induces endothelial permeability and shock.
Topics: Animals; Benzamidines; Capillary Permeability; Cell Line; Dengue; Dengue Virus; Endothelium, Vascula | 2019 |
Pancreatic proteases and inflammatory mediators in peritoneal fluid during splanchnic arterial occlusion and reperfusion.
Topics: Animals; Arteries; Benzamidines; Blood Pressure; Cardiovascular System; Endopeptidases; Enzyme Inhib | 2004 |
Inhibition of various immunological reactions in vivo by a new synthetic complement inhibitor.
Topics: Animals; Arthus Reaction; Benzamidines; Complement Inactivator Proteins; Forssman Antigen; Guanidine | 1982 |
[Problems in the use of newly introduced anti-shock agents].
Topics: Adrenal Cortex Hormones; Animals; Benzamidines; Complement Inactivator Proteins; Gabexate; Guanidine | 1983 |
Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes.
Topics: Animals; Benzamidines; Bile; Blood Pressure; Guanidines; Intestinal Mucosa; Intestines; Ischemia; Le | 2000 |
Inhibitory effects of newly synthesized active center-directed trypsin-like serine protease inhibitors on the complement system.
Topics: Animals; Benzamidines; Complement C1 Inactivator Proteins; Complement C1r; Complement C1s; Guanidine | 2000 |
The pancreas as a source of cardiovascular cell activating factors.
Topics: Animals; Benzamidines; Biological Factors; Blood Pressure; Cell Survival; Chemotactic Factors; Color | 2000 |
Plasma activation during splanchnic arterial occlusion shock.
Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Benzamidines; Biological Factors; Cats; Celiac | 2000 |
[Treatment of acute pancreatitis].
Topics: Acute Disease; Benzamidines; Disseminated Intravascular Coagulation; Drainage; Gabexate; Glycoprotei | 1992 |