nafamostat has been researched along with Reperfusion Injury in 12 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study clarifies the effects of nafamostat mesilate (NM), a strong serine protease inhibitor, and FR167653, a suppressant of both tumor necrosis factor-alpha and interleukin-1beta release, on warm ischemia-reperfusion injury and establishes the procurement of the grafts for a successful liver transplant using uncontrolled NHBDs." | 3.72 | Effects of anti-inflammatory cytokine agent (FR167653) and serine protease inhibitor on warm ischemia-reperfusion injury of the liver graft. ( Miyagi, S; Ohkohchi, N; Oikawa, K; Satoh, M; Satomi, S; Tsukamoto, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryu, HG | 1 |
| Jung, CW | 1 |
| Lee, CS | 1 |
| Lee, J | 1 |
| Gobbetti, T | 1 |
| Cenac, N | 1 |
| Motta, JP | 1 |
| Rolland, C | 1 |
| Martin, L | 1 |
| Andrade-Gordon, P | 1 |
| Steinhoff, M | 1 |
| Barocelli, E | 1 |
| Vergnolle, N | 1 |
| Miyagi, S | 1 |
| Ohkohchi, N | 2 |
| Oikawa, K | 1 |
| Satoh, M | 1 |
| Tsukamoto, S | 2 |
| Satomi, S | 2 |
| Ishimaru, K | 1 |
| Mitsuoka, H | 1 |
| Unno, N | 1 |
| Inuzuka, K | 1 |
| Nakamura, S | 1 |
| Schmid-Schönbein, GW | 2 |
| Urushihara, T | 2 |
| Sumimoto, K | 2 |
| Sumimoto, R | 2 |
| Ikeda, M | 2 |
| Fukuda, Y | 2 |
| Dohi, K | 2 |
| Shimizu, Y | 1 |
| Nakai, I | 1 |
| Morita, S | 1 |
| Uchiyama, K | 1 |
| Yoshimura, T | 1 |
| Itokawa, Y | 1 |
| Oka, T | 1 |
| Yamanaka, K | 1 |
| Okugawa, K | 1 |
| Sakimoto, H | 1 |
| Nishihara, M | 1 |
| Kimura, T | 1 |
| Andoh, A | 1 |
| Fujiyama, Y | 1 |
| Saotome, T | 1 |
| Bamba, T | 1 |
| Fukumori, T | 1 |
| Orii, T | 1 |
| Asakura, T | 1 |
| Takayama, J | 1 |
| Shibuya, H | 1 |
| Kato, H | 1 |
| Kistler, EB | 1 |
| Lefer, AM | 1 |
| Hugli, TE | 1 |
| Kirschfink, M | 1 |
| Kuratani, T | 1 |
| Matsuda, H | 1 |
| Sawa, Y | 1 |
| Kaneko, M | 1 |
| Nakano, S | 1 |
| Kawashima, Y | 1 |
1 review available for nafamostat and Reperfusion Injury
| Article | Year |
|---|---|
Targeting complement in therapy.
Topics: Anaphylatoxins; Angioedema; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Antibo | 2001 |
1 trial available for nafamostat and Reperfusion Injury
| Article | Year |
|---|---|
Nafamostat mesilate attenuates Postreperfusion Syndrome during liver transplantation.
Topics: Adult; Benzamidines; Double-Blind Method; Female; Guanidines; Humans; Infusions, Intravenous; Kallik | 2011 |
10 other studies available for nafamostat and Reperfusion Injury
| Article | Year |
|---|---|
Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine.
Topics: alpha-Macroglobulins; Animals; Benzamidines; Chemokines; Cysteine Proteinase Inhibitors; Granulocyte | 2012 |
Effects of anti-inflammatory cytokine agent (FR167653) and serine protease inhibitor on warm ischemia-reperfusion injury of the liver graft.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Benzamidines; Bile; Cyclooxygena | 2004 |
Pancreatic proteases and inflammatory mediators in peritoneal fluid during splanchnic arterial occlusion and reperfusion.
Topics: Animals; Arteries; Benzamidines; Blood Pressure; Cardiovascular System; Endopeptidases; Enzyme Inhib | 2004 |
Nafamostat mesilate rinse solution improves graft survival after rat pancreas and heart preservation.
Topics: Adenosine; Allopurinol; Animals; Benzamidines; Glutathione; Graft Survival; Guanidines; Heart; Heart | 1995 |
Nafamostat mesilate prevents warm ischemia-reperfusion injury in canine pancreas autotransplantation.
Topics: Animals; Benzamidines; Dogs; Guanidines; Male; Nitrites; Pancreas; Pancreas Transplantation; Proteas | 1995 |
Prevention of reperfusion injury after rat pancreas preservation using rinse solution containing nafamostat mesilate.
Topics: Adenosine; Allopurinol; Animals; Benzamidines; Blood Glucose; Glutathione; Graft Survival; Guanidine | 1996 |
A blockade of complement activation prevents rapid intestinal ischaemia-reperfusion injury by modulating mucosal mast cell degranulation in rats.
Topics: Anaphylatoxins; Animals; Benzamidines; Cell Degranulation; Cell Membrane Permeability; Chelating Age | 1998 |
Elimination of Kupffer cells and nafamostat mesilate rinse prevent reperfusion injury in liver grafts from agonal non-heart-beating donors.
Topics: Adenosine Triphosphate; Animals; Benzamidines; Bilirubin; Cell Survival; Energy Metabolism; Guanidin | 1999 |
Plasma activation during splanchnic arterial occlusion shock.
Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Benzamidines; Biological Factors; Cats; Celiac | 2000 |
Experimental study in a rabbit model of ischemia-reperfusion lung injury during cardiopulmonary bypass.
Topics: Adenosine Triphosphate; Animals; Benzamidines; Blood; Cardiopulmonary Bypass; Constriction; Guanidin | 1992 |