nafamostat has been researched along with Mucositis in 1 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Mucositis: An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to clarify the effect of nafamostat mesilate (nafamostat) on intestinal mucositis as well as the potentiation of intestinal 5-hydroxytryptamine (5-HT) dynamics induced by methotrexate, an anti-cancer drug, in rats." | 4.31 | Low-dose nafamostat mesilate ameliorates tissue injury and inhibits 5-hydroxytryptamine synthesis in the rat intestine after methotrexate administration. ( Hamaue, N; Hasebe, S; Hiraide, S; Iizuka, K; Kobayashi, N; Machida, T; Tamura, M; Tanno, C; Yamamoto, T, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamamoto, T | 1 |
| Machida, T | 1 |
| Tanno, C | 1 |
| Hasebe, S | 1 |
| Tamura, M | 1 |
| Kobayashi, N | 1 |
| Hiraide, S | 1 |
| Hamaue, N | 1 |
| Iizuka, K | 1 |
1 other study available for nafamostat and Mucositis
| Article | Year |
|---|---|
Low-dose nafamostat mesilate ameliorates tissue injury and inhibits 5-hydroxytryptamine synthesis in the rat intestine after methotrexate administration.
Topics: Animals; Guanidines; Intestines; Methotrexate; Mucositis; Rats; Serotonin | 2023 |