nafamostat has been researched along with Kidney Failure, Chronic in 16 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nafamostat mesylate has a similar profile of anti-coagulative activity to heparin." | 5.35 | Superior outcome of nafamostat mesilate as an anticoagulant in patients undergoing maintenance hemodialysis with intracerebral hemorrhage. ( Choi, SO; Han, BG; Kim, BR; Kim, YS; Lee, YH; Yang, JW; Yu, JM, 2009) |
| "Therefore, hemodialysis using an arteriovenous fistula was induced for renal replacement therapy." | 1.56 | Induction of hemodialysis with an arteriovenous fistula in a patient with hemophilia A. ( Aomatsu, A; Hirai, K; Hoshino, T; Ishii, H; Ito, K; Kaku, Y; Kaneko, S; Kitano, T; Matsuyama, M; Minato, S; Miyazawa, H; Miyoshi, C; Morino, J; Morishita, Y; Ookawara, S; Shimoyama, H; Shindo, M; Ueda, Y; Yanai, K, 2020) |
| "Nafamostat mesylate has a similar profile of anti-coagulative activity to heparin." | 1.35 | Superior outcome of nafamostat mesilate as an anticoagulant in patients undergoing maintenance hemodialysis with intracerebral hemorrhage. ( Choi, SO; Han, BG; Kim, BR; Kim, YS; Lee, YH; Yang, JW; Yu, JM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, H | 1 |
| Miyoshi, C | 1 |
| Hirai, K | 1 |
| Morino, J | 1 |
| Minato, S | 1 |
| Kaneko, S | 1 |
| Yanai, K | 1 |
| Matsuyama, M | 1 |
| Kitano, T | 1 |
| Shindo, M | 1 |
| Aomatsu, A | 1 |
| Shimoyama, H | 1 |
| Miyazawa, H | 1 |
| Ito, K | 1 |
| Ueda, Y | 1 |
| Kaku, Y | 1 |
| Hoshino, T | 1 |
| Ookawara, S | 1 |
| Morishita, Y | 1 |
| Yang, JW | 1 |
| Han, BG | 1 |
| Kim, BR | 1 |
| Lee, YH | 1 |
| Kim, YS | 1 |
| Yu, JM | 1 |
| Choi, SO | 1 |
| Hara, T | 1 |
| Jojima, K | 1 |
| Takeuchi, K | 1 |
| Takai, K | 1 |
| Naito, K | 1 |
| Inoue, K | 1 |
| Yoshiba, M | 1 |
| Ogata, H | 1 |
| Kinugasa, E | 2 |
| Hara, S | 1 |
| Ubara, Y | 1 |
| Sugimura, K | 1 |
| Kim, T | 1 |
| Goto, T | 1 |
| Kasai, S | 1 |
| Takemoto, Y | 1 |
| Matsuda, J | 1 |
| Yoshimoto, M | 1 |
| Yamagami, S | 1 |
| Kishimoto, T | 1 |
| Hoshino, R | 1 |
| Okubo, T | 1 |
| Kaneko, K | 1 |
| Goko, C | 1 |
| Maruyama, H | 1 |
| Miyakawa, Y | 1 |
| Gejyo, F | 2 |
| Arakawa, M | 1 |
| Fujisawa, K | 1 |
| Matsumoto, Y | 1 |
| Muramatsu, H | 1 |
| Shinzato, T | 1 |
| Hiramatsu, K | 1 |
| Horie, K | 1 |
| Cai, Z | 1 |
| Oka, H | 1 |
| Amano, I | 1 |
| Muramatsu, T | 1 |
| Maeda, K | 1 |
| Matsuo, T | 1 |
| Matsuo, M | 1 |
| Kario, K | 1 |
| Koide, M | 1 |
| Higuchi, N | 1 |
| Yamazaki, H | 1 |
| Kikuchi, H | 1 |
| Wake, M | 1 |
| Sanagawa, Y | 1 |
| Tanaka, Y | 1 |
| Makita, T | 1 |
| Akizawa, T | 1 |
| Koshikawa, S | 1 |
| Terada, H | 1 |
| Takahashi, H | 1 |
| Shibata, A | 1 |
3 reviews available for nafamostat and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Blood purification for patients with chronic renal failure accompanied by severe liver disease].
Topics: Acute Disease; Anticoagulants; Benzamidines; Carrier State; Cellulose; Chronic Disease; Dialysis Sol | 2004 |
[Treatment of uremic patients with high bleeding risk].
Topics: Anticoagulants; Benzamidines; Blood Platelet Disorders; Guanidines; Hemorrhage; Heparin, Low-Molecul | 2004 |
[Uremic pericarditis].
Topics: Anticoagulants; Benzamidines; Cardiac Surgical Procedures; Death; Dialysis; Drainage; Glucocorticoid | 2007 |
1 trial available for nafamostat and Kidney Failure, Chronic
| Article | Year |
|---|---|
Increased serum midkine levels during hemodialysis using heparin in chronic renal failure.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anticoagulants; Benzamidines; Carrier Proteins; Cytokines; | 1998 |
12 other studies available for nafamostat and Kidney Failure, Chronic
| Article | Year |
|---|---|
Induction of hemodialysis with an arteriovenous fistula in a patient with hemophilia A.
Topics: Aged, 80 and over; Anticoagulants; Arteriovenous Fistula; Benzamidines; Coagulants; Factor VIII; Gua | 2020 |
Superior outcome of nafamostat mesilate as an anticoagulant in patients undergoing maintenance hemodialysis with intracerebral hemorrhage.
Topics: Aged; Anticoagulants; Benzamidines; Cerebral Hemorrhage; Female; Guanidines; Humans; Kidney Failure, | 2009 |
Intraoperative management of a congenital antithrombin deficient patient on chronic hemodialysis.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Benzamidines; Guanidines; Humans; Intraoperative Care | 2004 |
Serum hepatocyte growth factor levels in patients with chronic renal failure.
Topics: Adult; Aged; Antithrombins; Benzamidines; Female; Guanidines; Heparin; Hepatocyte Growth Factor; Hum | 1995 |
[Cardiac surgery in hemodialysis patients].
Topics: Adult; Antithrombins; Benzamidines; Coronary Artery Bypass; Extracorporeal Circulation; Female; Guan | 1993 |
Anaphylactoid reaction induced by nafamostat mesilate in a hemodialysis patient.
Topics: Anaphylaxis; Anticoagulants; Benzamidines; Equipment Failure; Female; Guanidines; Humans; Kidney Fai | 1996 |
Effect of an anticoagulant (heparin versus nafamostat mesilate) on the extrinsic coagulation pathway in chronic hemodialysis.
Topics: Adult; Aged; Anticoagulants; Benzamidines; Blood Coagulation Factors; Female; Guanidines; Heparin; H | 1998 |
Anaphylactoid reaction induced by a protease inhibitor, nafamostat mesilate, following nine administrations in a hemodialysis patient.
Topics: Aged; Anaphylaxis; Benzamidines; Guanidines; Humans; Kidney Failure, Chronic; Male; Protease Inhibit | 2000 |
[Management of intraoperative anticoagulantless CHD with EVAL-dialyzer in four patients on maintenance hemodialysis].
Topics: Adult; Aged; Benzamidines; Female; Guanidines; Humans; Intraoperative Care; Kidney Failure, Chronic; | 2002 |
[Treatment of uremic patients at high bleeding risk].
Topics: Benzamidines; Blood Transfusion; Deamino Arginine Vasopressin; Gabexate; Guanidines; Hemorrhage; Hep | 1992 |
[Changes in platelets, coagulation and fibrinolysis in patients with chronic kidney diseases and hemodialysis].
Topics: Benzamidines; Blood Coagulation; Blood Platelets; Epoprostenol; Fibrinolysis; Gabexate; Guanidines; | 1992 |
[Bleeding tendency in chronic kidney failure with hemodialysis].
Topics: Benzamidines; Deamino Arginine Vasopressin; Estrogens; Factor VIII; Fibrinogen; Guanidines; Hemorrha | 1992 |