nafamostat has been researched along with Intracranial Hemorrhages in 3 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Intracranial Hemorrhages: Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nafamostat mesilate (NM) is a synthetic protease-inhibiting agent that has not only potent inhibitory activity against coagulation factors (Xlla, Xa) but also an anti-inflammatory action." | 5.40 | Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke. ( Gotake, Y; Inoue, T; Izawa, N; Kano, H; Matsumori, M; Miyahara, S; Okada, K; Okita, Y; Sakamoto, T, 2014) |
| "Nafamostat mesilate (NM) is a synthetic protease-inhibiting agent that has not only potent inhibitory activity against coagulation factors (Xlla, Xa) but also an anti-inflammatory action." | 1.40 | Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke. ( Gotake, Y; Inoue, T; Izawa, N; Kano, H; Matsumori, M; Miyahara, S; Okada, K; Okita, Y; Sakamoto, T, 2014) |
| "Generally, patients with a recent intracranial hemorrhage are believed to be a contraindication to undergo cardiac surgery with cardiopulmonary bypass." | 1.34 | Cardiopulmonary bypass using nafamostat mesilate for patients with infective endocarditis and recent intracranial hemorrhage. ( Kano, H; Okada, K; Okita, Y; Ota, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakamoto, T | 1 |
| Kano, H | 2 |
| Miyahara, S | 1 |
| Inoue, T | 1 |
| Izawa, N | 1 |
| Gotake, Y | 1 |
| Matsumori, M | 1 |
| Okada, K | 2 |
| Okita, Y | 2 |
| Morimoto, N | 1 |
| Henmi, S | 1 |
| Yoshida, M | 1 |
| Mukohara, N | 1 |
| Ota, T | 1 |
3 other studies available for nafamostat and Intracranial Hemorrhages
| Article | Year |
|---|---|
Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke.
Topics: Adult; Aged; Anticoagulants; Benzamidines; Blood Coagulation Tests; Cardiac Surgical Procedures; Car | 2014 |
Cardiopulmonary bypass strategy with low-dose heparin and nafamostat mesilate in cardiac surgery: a safe option for patients with acute stroke.
Topics: Aged; Aged, 80 and over; Anticoagulants; Benzamidines; Cardiac Surgical Procedures; Cardiopulmonary | 2012 |
Cardiopulmonary bypass using nafamostat mesilate for patients with infective endocarditis and recent intracranial hemorrhage.
Topics: Adult; Aged; Benzamidines; Cardiopulmonary Bypass; Endocarditis, Bacterial; Female; Guanidines; Huma | 2007 |