Compounds > nafamostat
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nafamostat and Extravascular Hemolysis

nafamostat has been researched along with Extravascular Hemolysis in 11 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Research Excerpts

ExcerptRelevanceReference
", Forssman shock, Forssman cutaneous vasculitis, zymosan-induced paw edema, endotoxin shock and local Shwartzman reaction, FUT-175 was highly effective in that, for example, intravenous dosing at 3 mg/kg could completely protect guinea pigs from the lethal Forssman shock."1.27Pharmacological studies of FUT-175, nafamstat mesilate. I. Inhibition of protease activity in in vitro and in vivo experiments. ( Aoyama, T; Fujita, M; Ino, Y; Koshiyama, Y; Oda, M; Ozeki, M; Sato, T; Suzuki, S, 1984)
"and 25 mg/kg p."1.26Inhibition of various immunological reactions in vivo by a new synthetic complement inhibitor. ( Fujii, S; Hitomi, Y, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujita, H1
Sakuma, R1
Fujimoto, S1
Hazama, Y1
Ohtake, C1
Moriyama, A1
Kuhara, K1
Nishimura, S1
Hitomi, Y2
Fujii, S2
Iwaki, M3
Oda, M3
Ozeki, M2
Ino, Y5
Suzuki, K2
Koshiyama, Y2
Motoyoshi, A1
Ogihara, M1
Suzuki, S4
Fujita, M2
Aoyama, T1
Sato, T3
Ikari, N1
Sakai, Y1
Miyagawa, S2
Shirakura, R2
Matsumiya, G2
Fukushima, N2
Nakata, S2
Matsuda, H1
Matsumoto, M2
Kitamura, H2
Seya, T2
Mukai, S1
Orihashi, K1
Sueda, T1
Kajihara, H1
Matsuura, Y1
Ueda, N1
Midorikawa, A1
Nakamura, K1
Kurumi, M1
Kitagawa, S1
Nakano, S1
Yoshikawa, T1

Other Studies

11 other studies available for nafamostat and Extravascular Hemolysis

ArticleYear
Nafamostat mesilate, a noncalcium compound, as an anticoagulant, induces calcium-dependent haemolysis when infused with packed erythrocytes.
    Transfusion medicine (Oxford, England), 2012, Volume: 22, Issue:3

    Topics: Anticoagulants; Benzamidines; Calcium; Citrates; Citric Acid; Drug Evaluation, Preclinical; Edetic A

2012
Inhibition of various immunological reactions in vivo by a new synthetic complement inhibitor.
    International archives of allergy and applied immunology, 1982, Volume: 69, Issue:3

    Topics: Animals; Arthus Reaction; Benzamidines; Complement Inactivator Proteins; Forssman Antigen; Guanidine

1982
[Pharmacological studies of FUT-175, nafamstat mesilate. III. Anti-inflammatory activities of FUT-175].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 84, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; Benzamidines; Capillary Permeability; Chemotaxis

1984
Pharmacological studies of FUT-175, nafamstat mesilate. I. Inhibition of protease activity in in vitro and in vivo experiments.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Benzamidines; Complement Activation; Complement Inactivator Prote

1984
New synthetic inhibitor to the alternative complement pathway.
    Immunology, 1983, Volume: 49, Issue:4

    Topics: Animals; Benzamidines; Complement Activation; Complement Factor B; Complement Factor D; Complement I

1983
Prolonging discordant xenograft survival with anticomplement reagents K76COOH and FUT175.
    Transplantation, 1993, Volume: 55, Issue:4

    Topics: Animals; Benzamidines; Complement C3; Complement Factor B; Complement Factor D; Complement Inactivat

1993
Effects of complement suppression on xenograft survival in hyperacute rejection.
    Hiroshima journal of medical sciences, 1999, Volume: 48, Issue:1

    Topics: Animals; Benzamidines; Complement Hemolytic Activity Assay; Complement Inactivator Proteins; Complem

1999
Inhibitory effects of newly synthesized active center-directed trypsin-like serine protease inhibitors on the complement system.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:1

    Topics: Animals; Benzamidines; Complement C1 Inactivator Proteins; Complement C1r; Complement C1s; Guanidine

2000
Effect of anticomplement reagents, K-76 COOH and FUT175, on discordant xenograft survival.
    Transplantation proceedings, 1992, Volume: 24, Issue:2

    Topics: Animals; Antibodies; Benzamidines; Complement Inactivator Proteins; Complement System Proteins; Cyto

1992
[Comparative studies of nafamostat mesilate and various serine protease inhibitors in vitro].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:6

    Topics: alpha-Macroglobulins; Aprotinin; Benzamidines; Complement Inactivator Proteins; Gabexate; Glycoprote

1986
Inhibitory effects of FUT-175, a new synthetic protease inhibitor, on intravascular hemolysis by human serum in mice.
    International journal of immunopharmacology, 1987, Volume: 9, Issue:5

    Topics: Animals; Benzamidines; Blood Physiological Phenomena; Dogs; Erythrocytes; Guanidines; Guinea Pigs; H

1987