nafamostat has been researched along with Eosinophilia in 4 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nafamostat was administered in a mouse model for asthma based on sensitization by house dust mite (HDM) extract, followed by the assessment of effects on airway hyperreactivity, inflammatory parameters and gene expression." | 8.31 | Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity. ( Akula, S; Allam, VSRR; Pejler, G; Taha, S; Waern, I; Wernersson, S, 2023) |
| "We sought to investigate the effects of serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on airway inflammation in a mouse model of allergic asthma." | 7.73 | Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. ( Chen, CL; Kao, ST; Lin, KJ; Tani, T; Wang, JY; Wang, SD; Yu, CK; Zeng, ZY, 2006) |
| "A 61-year-old Japanese female on hemodialysis developed marked eosinophilia induced by nafamostat mesilate as an anticoagulant for hemodialysis." | 7.68 | Marked eosinophilia induced by nafamostat mesilate, an anticoagulant in a hemodialysis patient. ( Fujii, M; Horio, M; Kaneko, T; Kashiwai, K; Kawagoe, H; Nakanishi, K; Yano, F, 1992) |
| "Nafamostat was administered in a mouse model for asthma based on sensitization by house dust mite (HDM) extract, followed by the assessment of effects on airway hyperreactivity, inflammatory parameters and gene expression." | 4.31 | Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity. ( Akula, S; Allam, VSRR; Pejler, G; Taha, S; Waern, I; Wernersson, S, 2023) |
| "We sought to investigate the effects of serine protease inhibitors nafamostat mesilate (FUT), gabexate mesilate (FOY), and ulinastatin (UTI) on airway inflammation in a mouse model of allergic asthma." | 3.73 | Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. ( Chen, CL; Kao, ST; Lin, KJ; Tani, T; Wang, JY; Wang, SD; Yu, CK; Zeng, ZY, 2006) |
| "A 61-year-old Japanese female on hemodialysis developed marked eosinophilia induced by nafamostat mesilate as an anticoagulant for hemodialysis." | 3.68 | Marked eosinophilia induced by nafamostat mesilate, an anticoagulant in a hemodialysis patient. ( Fujii, M; Horio, M; Kaneko, T; Kashiwai, K; Kawagoe, H; Nakanishi, K; Yano, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allam, VSRR | 1 |
| Waern, I | 1 |
| Taha, S | 1 |
| Akula, S | 1 |
| Wernersson, S | 1 |
| Pejler, G | 1 |
| Legrand, F | 1 |
| Driss, V | 1 |
| Delbeke, M | 1 |
| Loiseau, S | 1 |
| Hermann, E | 1 |
| Dombrowicz, D | 1 |
| Capron, M | 1 |
| Chen, CL | 1 |
| Wang, SD | 1 |
| Zeng, ZY | 1 |
| Lin, KJ | 1 |
| Kao, ST | 1 |
| Tani, T | 1 |
| Yu, CK | 1 |
| Wang, JY | 1 |
| Nakanishi, K | 1 |
| Kaneko, T | 1 |
| Yano, F | 1 |
| Horio, M | 1 |
| Kawagoe, H | 1 |
| Fujii, M | 1 |
| Kashiwai, K | 1 |
4 other studies available for nafamostat and Eosinophilia
| Article | Year |
|---|---|
Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Eosinophilia; Eosinophils; Gene Expression; Human | 2023 |
Human eosinophils exert TNF-α and granzyme A-mediated tumoricidal activity toward colon carcinoma cells.
Topics: Antibodies; Apoptosis; Benzamidines; CD11a Antigen; CD18 Antigens; Cell Line, Tumor; Coculture Techn | 2010 |
Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.
Topics: Animals; Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Benzamidines; Chemokines; Cysteine | 2006 |
Marked eosinophilia induced by nafamostat mesilate, an anticoagulant in a hemodialysis patient.
Topics: Anticoagulants; Benzamidines; Eosinophilia; Female; Guanidines; Humans; Middle Aged; Renal Dialysis | 1992 |