nafamostat has been researched along with Endocarditis in 1 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nafamostat mesilate (NM) is a synthetic protease-inhibiting agent that has not only potent inhibitory activity against coagulation factors (Xlla, Xa) but also an anti-inflammatory action." | 5.40 | Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke. ( Gotake, Y; Inoue, T; Izawa, N; Kano, H; Matsumori, M; Miyahara, S; Okada, K; Okita, Y; Sakamoto, T, 2014) |
| "Nafamostat mesilate (NM) is a synthetic protease-inhibiting agent that has not only potent inhibitory activity against coagulation factors (Xlla, Xa) but also an anti-inflammatory action." | 1.40 | Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke. ( Gotake, Y; Inoue, T; Izawa, N; Kano, H; Matsumori, M; Miyahara, S; Okada, K; Okita, Y; Sakamoto, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakamoto, T | 1 |
| Kano, H | 1 |
| Miyahara, S | 1 |
| Inoue, T | 1 |
| Izawa, N | 1 |
| Gotake, Y | 1 |
| Matsumori, M | 1 |
| Okada, K | 1 |
| Okita, Y | 1 |
1 other study available for nafamostat and Endocarditis
| Article | Year |
|---|---|
Efficacy of nafamostat mesilate as anticoagulation during cardiopulmonary bypass for early surgery in patients with active infective endocarditis complicated by stroke.
Topics: Adult; Aged; Anticoagulants; Benzamidines; Blood Coagulation Tests; Cardiac Surgical Procedures; Car | 2014 |