Page last updated: 2024-10-31

nafamostat and Disseminated Intravascular Coagulation

nafamostat has been researched along with Disseminated Intravascular Coagulation in 34 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Disseminated Intravascular Coagulation: A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.

Research Excerpts

ExcerptRelevanceReference
"After 9 years of treatment for Parkinson's disease, a 68-year-old woman developed the complications of neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) while she was still receiving levodopa, bromocriptine and amantadine hydrochloride."8.78Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease. ( Ogawa, N; Yamawaki, Y, 1992)
"Nafamostat, a serine proteinase inhibitor with various actions including antithrombin, antiplasmin, and antitrypsin effects, has been used in clinical practice to treat disseminated intravascular coagulation (DIC) and pancreatitis."8.02Potential mechanisms of nafamostat therapy for severe COVID-19 pneumonia with disseminated intravascular coagulation. ( Asakura, H; Koba, H; Ogawa, H; Takahashi, W; Tsuji, N; Ueda, T; Yoneda, T, 2021)
"We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synthetic protease inhibitors (SPIs) and compared the effects of gabexate mesilate (FOY) and nafamostat mesilate (FUT)."7.91Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, SI; Kawasaki, Y; Mashima, K; Minakata, D; Morita, K; Muroi, K; Nagayama, T; Nakano, H; Ochi, SI; Oh, I; Ohmine, K; Ohmori, T; Sato, K; Sugimoto, M; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R, 2019)
"Effects of dermatan sulfate (DS) on the endotoxin-induced disseminated intravascular coagulation (DIC) rat model were compared with those of low-molecular weight heparin (LMWH), nafamostat mesilate (NM) and argathroban (AR)."7.70Effects of dermatan sulfate, a heparin cofactor II mediated thrombin inhibitor, on the endotoxin-induced disseminated intravascular coagulation model in the rat: comparison with low-molecular weight heparin, nafamostat mesilate and argathroban. ( Horie, K; Kyogashima, M; Miyauchi, S; Mizuno, S; Onaya, J; Sunose, A, 1998)
"FUT has been reported as a drug for the treatments of DIC (disseminated intravascular coagulation) and acute pancreatitis and as an anticoagulant in extracorporeal circulation."6.41[Pharmacokinetics studies of nafamostat mesilate (FUT), a synthetic protease inhibitor, which has been used for the treatments of DIC and acute pancreatitis, and as an anticoagulant in extracorporeal circulation]. ( Tsukagoshi, S, 2000)
"Dantrolene was effective on the elevated COK level and FUT-175 was effective on the DIC, and symptoms of NMS and DIC were completely improved after a period of 14 days."6.38[Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) with disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease]. ( Ogawa, N; Yamawaki, Y, 1991)
"A 65-year-old man with chronic aortic dissection experienced two massive subcutaneous hemorrhages."5.35Effects of nafamostat mesilate on coagulopathy with chronic aortic dissection. ( Hiraiwa, T; Ito, H; Tanaka, K; Yamamoto, K, 2009)
"Nafamostat mesilate was considered effective for HANE attack."5.28[Hereditary angioneurotic edema associated with DIC and treated effectively by nafamostat mesilate]. ( Kayashima, S; Kimura, F; Makishima, M; Matuura, Y; Mineshita, M; Sasaki, T; Satou, N; Shimomura, S; Takagi, S; Yamamoto, K, 1992)
"After 9 years of treatment for Parkinson's disease, a 68-year-old woman developed the complications of neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) while she was still receiving levodopa, bromocriptine and amantadine hydrochloride."4.78Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease. ( Ogawa, N; Yamawaki, Y, 1992)
"Nafamostat, a serine proteinase inhibitor with various actions including antithrombin, antiplasmin, and antitrypsin effects, has been used in clinical practice to treat disseminated intravascular coagulation (DIC) and pancreatitis."4.02Potential mechanisms of nafamostat therapy for severe COVID-19 pneumonia with disseminated intravascular coagulation. ( Asakura, H; Koba, H; Ogawa, H; Takahashi, W; Tsuji, N; Ueda, T; Yoneda, T, 2021)
"We evaluated clinical outcomes of disseminated intravascular coagulation (DIC) in patients with hematological malignancies treated with synthetic protease inhibitors (SPIs) and compared the effects of gabexate mesilate (FOY) and nafamostat mesilate (FUT)."3.91Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, SI; Kawasaki, Y; Mashima, K; Minakata, D; Morita, K; Muroi, K; Nagayama, T; Nakano, H; Ochi, SI; Oh, I; Ohmine, K; Ohmori, T; Sato, K; Sugimoto, M; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R, 2019)
"Effects of dermatan sulfate (DS) on the endotoxin-induced disseminated intravascular coagulation (DIC) rat model were compared with those of low-molecular weight heparin (LMWH), nafamostat mesilate (NM) and argathroban (AR)."3.70Effects of dermatan sulfate, a heparin cofactor II mediated thrombin inhibitor, on the endotoxin-induced disseminated intravascular coagulation model in the rat: comparison with low-molecular weight heparin, nafamostat mesilate and argathroban. ( Horie, K; Kyogashima, M; Miyauchi, S; Mizuno, S; Onaya, J; Sunose, A, 1998)
"Nafamostat mesilate (NM), a synthetic protease inhibitor, is frequently used for the treatment of disseminated intravascular coagulation (DIC) in Japan."3.69Effect of nafamostat mesilate, a synthetic protease inhibitor, on tissue factor-factor VIIa complex activity. ( Abe, H; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M, 1994)
"The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms."2.72COVID-19-associated coagulopathy and disseminated intravascular coagulation. ( Asakura, H; Ogawa, H, 2021)
"Whereas in DIC associated with trauma, since balance between coagulation and fibrinolysis collapses drastically in a short period, both anticoagulantion therapy and antifibrinolytic therapy can be utilized depending on clinical conditions."2.53[Anti DIC therapy]. ( Sakamoto, Y; Yahata, M, 2016)
"FUT has been reported as a drug for the treatments of DIC (disseminated intravascular coagulation) and acute pancreatitis and as an anticoagulant in extracorporeal circulation."2.41[Pharmacokinetics studies of nafamostat mesilate (FUT), a synthetic protease inhibitor, which has been used for the treatments of DIC and acute pancreatitis, and as an anticoagulant in extracorporeal circulation]. ( Tsukagoshi, S, 2000)
"5 days later he developed adult respiratory distress syndrome (ARDS)."2.39[A case of adult onset Still's disease complicated with adult respiratory distress syndrome and disseminated intravascular coagulation]. ( Akizuki, M; Fujii, T; Ichikawa, Y; Mimori, T; Shinozawa, T; Suwa, A; Tojo, T; Yokoyama, M, 1995)
"Dantrolene was effective on the elevated COK level and FUT-175 was effective on the DIC, and symptoms of NMS and DIC were completely improved after a period of 14 days."2.38[Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) with disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease]. ( Ogawa, N; Yamawaki, Y, 1991)
"She developed disseminated intravascular coagulation on the fourth day after admission."1.40Adult-onset Still's disease with disseminated intravascular coagulation and hemophagocytic syndrome: a case report. ( Kibata, M; Mimura, T; Shimodaira, M; Shirahata, K; Tsukadaira, A, 2014)
"A 65-year-old man with chronic aortic dissection experienced two massive subcutaneous hemorrhages."1.35Effects of nafamostat mesilate on coagulopathy with chronic aortic dissection. ( Hiraiwa, T; Ito, H; Tanaka, K; Yamamoto, K, 2009)
"Nafamostat mesilate was considered effective for HANE attack."1.28[Hereditary angioneurotic edema associated with DIC and treated effectively by nafamostat mesilate]. ( Kayashima, S; Kimura, F; Makishima, M; Matuura, Y; Mineshita, M; Sasaki, T; Satou, N; Shimomura, S; Takagi, S; Yamamoto, K, 1992)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19905 (14.71)18.7374
1990's14 (41.18)18.2507
2000's3 (8.82)29.6817
2010's10 (29.41)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Takahashi, W1
Yoneda, T1
Koba, H1
Ueda, T1
Tsuji, N1
Ogawa, H2
Asakura, H2
Minakata, D1
Fujiwara, SI1
Ikeda, T1
Kawaguchi, SI1
Toda, Y1
Ito, S1
Ochi, SI1
Nagayama, T1
Mashima, K1
Umino, K1
Nakano, H1
Yamasaki, R1
Morita, K1
Kawasaki, Y1
Sugimoto, M1
Yamamoto, C1
Ashizawa, M1
Hatano, K1
Sato, K1
Oh, I1
Ohmine, K1
Muroi, K1
Ohmori, T1
Kanda, Y1
Wada, H1
Matsumoto, T1
Yamashita, Y1
Mimura, T1
Shimodaira, M1
Kibata, M1
Tsukadaira, A1
Shirahata, K1
Machioka, K1
Shigehara, K1
Kadomoto, S1
Iwamoto, H1
Miyagi, T1
Nakashima, T1
Namiki, M1
Nishimura, H1
Yamaya, M1
Kawano, H1
Hata, T1
Uda, A1
Maemura, K1
Goto, S1
Ookawara, S1
Tabei, K1
Yahata, M1
Sakamoto, Y1
Yamamoto, K2
Ito, H1
Hiraiwa, T1
Tanaka, K1
Koyama, T1
Takahashi, H1
Yoshikawa, T2
Murakami, M2
Furukawa, Y2
Onodera, H1
Yoshida, N1
Ueda, M1
Kato, H2
Takemura, S2
Sugino, S1
Kondo, M2
Denno, R1
Hasegawa, I1
Sasaki, K1
Gotoh, Y1
Ebata, T1
Totsuka, M1
Hayasaka, H1
Yokoyama, M1
Suwa, A1
Shinozawa, T1
Fujii, T1
Mimori, T1
Akizuki, M1
Ichikawa, Y1
Tojo, T1
Ohsawa, T1
Tsubota, M1
Endo, M1
Kobayashi, K1
Sato, H1
Seki, M1
Uchiba, M1
Okajima, K1
Abe, H1
Okabe, H1
Takatsuki, K1
Aramoto, H1
Saito, H1
Shigematsu, H1
Muto, T1
Suzuki, H1
Nimura, Y1
Kamiya, J1
Kondo, S1
Nagino, M1
Kanai, M1
Miyachi, M1
Onaya, J1
Kyogashima, M1
Sunose, A1
Miyauchi, S1
Mizuno, S1
Horie, K1
Tsukagoshi, S2
Kashima, K1
Kataoka, K1
Umehara, K1
Yamawaki, Y2
Ogawa, N2
Mineshita, M1
Kayashima, S1
Makishima, M1
Kimura, F1
Sasaki, T1
Takagi, S1
Matuura, Y1
Shimomura, S1
Satou, N1
Murakawa, M1
Okamura, T1
Shibuya, T1
Harada, M1
Otsuka, T1
Niho, Y1
Yoshida, K1
Toki, F1
Takeuchi, T1
Kuroda, T1
Suzuki, S1
Konno, M1
Amano, T1
Mikame, M1
Okamoto, K1
Takeda, S1
Ohsato, K1
Takemoto, Y1
Tanaka, S1
Tanabe, J1
Nakamura, Y1
Kohama, A1
Shibata, S1
Koshiyama, Y1
Kobori, A1
Ogihara, M1
Yokomoto, Y1
Ohtani, K1
Shimamura, K1
Iwaki, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
RAndomized Clinical Trial in COvid19 Patients to Assess the Efficacy of the Transmembrane Protease Serine 2 (TMPRSS2) Inhibitor NAfamostat (RACONA Study)[NCT04352400]Phase 2/Phase 3256 participants (Anticipated)Interventional2021-06-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for nafamostat and Disseminated Intravascular Coagulation

ArticleYear
COVID-19-associated coagulopathy and disseminated intravascular coagulation.
    International journal of hematology, 2021, Volume: 113, Issue:1

    Topics: Adult; Anticoagulants; Benzamidines; Blood Coagulation Disorders; Blood Coagulation Tests; COVID-19;

2021
[Recent therapeutic strategy for disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2014
[Anti DIC therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzamidines; Disseminated Intravascular Coa

2016
[Treatment of disseminated intravascular coagulation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2010, Volume: 51, Issue:1

    Topics: Anticoagulants; Antithrombins; Benzamidines; Chondroitin Sulfates; Dalteparin; Dermatan Sulfate; Dis

2010
[Synthetic protease inhibitors for the treatment of DIC].
    Rinsho byori. The Japanese journal of clinical pathology, 2011, Volume: Suppl 147

    Topics: Anticoagulants; Arginine; Benzamidines; Disseminated Intravascular Coagulation; Gabexate; Guanidines

2011
[A case of adult onset Still's disease complicated with adult respiratory distress syndrome and disseminated intravascular coagulation].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 1995, Volume: 18, Issue:2

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzamidines; Disseminated

1995
[Synthetic protease inhibitors in the treatment of disseminated intravascular coagulation].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:1

    Topics: Benzamidines; Disseminated Intravascular Coagulation; Gabexate; Glycoproteins; Guanidines; Half-Life

1993
Preoperative transcatheter arterial embolization for giant cavernous hemangioma of the liver with consumption coagulopathy.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:4

    Topics: Adult; Anticoagulants; Benzamidines; Combined Modality Therapy; Disseminated Intravascular Coagulati

1997
[Pharmacokinetics studies of nafamostat mesilate (FUT), a synthetic protease inhibitor, which has been used for the treatments of DIC and acute pancreatitis, and as an anticoagulant in extracorporeal circulation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:5

    Topics: Acute Disease; Adult; Anticoagulants; Benzamidines; Disseminated Intravascular Coagulation; Extracor

2000
[Molecular specificity of nafamostat mesilate (FUT), a drug used for the treatments of DIC and acute pancreatitis and as an anticoagulant--the pharmacodynamics and pharmacological action].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:9

    Topics: Benzamidines; Disseminated Intravascular Coagulation; Guanidines; Humans; Inhibitory Concentration 5

2001
Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) and disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:11

    Topics: Aged; Antithrombins; Benzamidines; Dantrolene; Disseminated Intravascular Coagulation; Female; Guani

1992
[Successful treatment of levodopa-induced neuroleptic malignant syndrome (NMS) with disseminated intravascular coagulation (DIC) in a patient with Parkinson's disease].
    Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:1

    Topics: Aged; Benzamidines; Dantrolene; Disseminated Intravascular Coagulation; Female; Guanidines; Humans;

1991

Other Studies

22 other studies available for nafamostat and Disseminated Intravascular Coagulation

ArticleYear
Potential mechanisms of nafamostat therapy for severe COVID-19 pneumonia with disseminated intravascular coagulation.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 102

    Topics: Aged; Anticoagulants; Benzamidines; Blood Coagulation; COVID-19; Disseminated Intravascular Coagulat

2021
Comparison of gabexate mesilate and nafamostat mesilate for disseminated intravascular coagulation associated with hematological malignancies.
    International journal of hematology, 2019, Volume: 109, Issue:2

    Topics: Adult; Anticoagulants; Benzamidines; Disseminated Intravascular Coagulation; Female; Gabexate; Guani

2019
Adult-onset Still's disease with disseminated intravascular coagulation and hemophagocytic syndrome: a case report.
    BMC research notes, 2014, Dec-22, Volume: 7

    Topics: Anti-Inflammatory Agents; Benzamidines; Disseminated Intravascular Coagulation; Female; Guanidines;

2014
[Treatment with recombinant thrombomodulin on disseminated intravascular coagulation caused by urinary tract infections; a retrospective comparative study with control cases].
    Hinyokika kiyo. Acta urologica Japonica, 2015, Volume: 61, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Benzamidines; Disseminated Intravascular Coagulation; Femal

2015
A Synthetic Serine Protease Inhibitor, Nafamostat Mesilate, Is a Drug Potentially Applicable to the Treatment of Ebola Virus Disease.
    The Tohoku journal of experimental medicine, 2015, Volume: 237, Issue:1

    Topics: Animals; Antiviral Agents; Benzamidines; Disseminated Intravascular Coagulation; Ebolavirus; Factor

2015
Use of rivaroxaban for the effective management of disseminated intravascular coagulation associated with abdominal aortic aneurysm.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:20

    Topics: Aged; Anticoagulants; Aortic Aneurysm, Abdominal; Benzamidines; Blood Platelets; Blood Transfusion;

2015
Effectiveness of Plasma Exchange for Acute Pancreatitis Induced by Hypertriglyceridemia During Pregnancy.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2016, Volume: 20, Issue:1

    Topics: Adult; Anticoagulants; Benzamidines; Disseminated Intravascular Coagulation; Female; Guanidines; Hum

2016
Effects of nafamostat mesilate on coagulopathy with chronic aortic dissection.
    The Annals of thoracic surgery, 2009, Volume: 88, Issue:4

    Topics: Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Benzamidines; Blood Vessel Prosthesis Implantati

2009
[Inhibition of platelet aggregation and prevention of endotoxin-induced DIC by a protease inhibitor, FUT-175, in rats].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:4

    Topics: Animals; Benzamidines; Disseminated Intravascular Coagulation; Female; Guanidines; Humans; Platelet

1984
Effects of FUT-175, a new synthetic protease inhibitor on endotoxin-induced disseminated intravascular coagulation in rats.
    Haemostasis, 1983, Volume: 13, Issue:6

    Topics: Animals; Benzamidines; Disseminated Intravascular Coagulation; Endotoxins; Female; Fibrin Fibrinogen

1983
[Effects of new protease inhibitor (FUT-175) on experimental DIC].
    Masui. The Japanese journal of anesthesiology, 1984, Volume: 33, Issue:2

    Topics: Animals; Benzamidines; Blood Pressure; Disseminated Intravascular Coagulation; Endotoxins; Guanidine

1984
[A successfully treated case of thoracoabdominal aortic aneurysm complicated with the coagulation disorder].
    Kyobu geka. The Japanese journal of thoracic surgery, 1995, Volume: 48, Issue:9

    Topics: Aged; Anticoagulants; Antithrombins; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Benzamid

1995
Effect of nafamostat mesilate, a synthetic protease inhibitor, on tissue factor-factor VIIa complex activity.
    Thrombosis research, 1994, Apr-15, Volume: 74, Issue:2

    Topics: Amino Acid Sequence; Benzamidines; Blood Coagulation; Disseminated Intravascular Coagulation; Factor

1994
Effects of dermatan sulfate, a heparin cofactor II mediated thrombin inhibitor, on the endotoxin-induced disseminated intravascular coagulation model in the rat: comparison with low-molecular weight heparin, nafamostat mesilate and argathroban.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:4

    Topics: Animals; Arginine; Benzamidines; Dermatan Sulfate; Disease Models, Animal; Disseminated Intravascula

1998
[Treatment of acute pancreatitis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Dec-10, Volume: 81, Issue:12

    Topics: Acute Disease; Benzamidines; Disseminated Intravascular Coagulation; Drainage; Gabexate; Glycoprotei

1992
[Hereditary angioneurotic edema associated with DIC and treated effectively by nafamostat mesilate].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:1

    Topics: Adult; Angioedema; Benzamidines; Complement C1 Inactivator Proteins; Disseminated Intravascular Coag

1992
Use of a synthetic protease inhibitor for the treatment of L-asparaginase-induced acute pancreatitis complicated by disseminated intravascular coagulation.
    Annals of hematology, 1992, Volume: 64, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benz

1992
[Antienzyme preparations in the treatment of acute pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:1

    Topics: Acute Disease; Adult; Aprotinin; Benzamidines; Cytidine Diphosphate Choline; Disseminated Intravascu

1990
[A case of scrub typhus with disseminated intravascular coagulation, meningitis and pulmonary fibrosis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Nov-10, Volume: 80, Issue:11

    Topics: Benzamidines; Disseminated Intravascular Coagulation; Guanidines; Humans; Hydrocortisone; Male; Meni

1991
[Treatment of disseminated intravascular coagulation with proteinase inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Antithrombin III; Benzamidines; Disseminated Intravascular Coagulation; Drug Therapy, Combination; F

1991
Studies on the effects of primary therapy for DIC following circulatory arrest.
    American journal of hematology, 1986, Volume: 21, Issue:4

    Topics: Animals; Anticoagulants; Benzamidines; Blood Coagulation Tests; Disseminated Intravascular Coagulati

1986
[The effects of FUT-175 (nafamostat mesilate) on blood coagulation and experimental disseminated intravascular coagulation (DIC)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 90, Issue:6

    Topics: Animals; Benzamidines; Blood Coagulation; Disseminated Intravascular Coagulation; Guanidines; Male;

1987