Page last updated: 2024-10-31

nafamostat and Cholestasis

nafamostat has been researched along with Cholestasis in 1 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"In infants with biliary atresia, hepatic Granzymes A and B mRNA, but not Perforin, increased at the time of portoenterostomy."1.40Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia. ( Bezerra, JA; Mourya, R; Shivakumar, P, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shivakumar, P1
Mourya, R1
Bezerra, JA1

Other Studies

1 other study available for nafamostat and Cholestasis

ArticleYear
Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia.
    Journal of hepatology, 2014, Volume: 60, Issue:2

    Topics: Animals; Animals, Newborn; Benzamidines; Bile Ducts; Biliary Atresia; CD8-Positive T-Lymphocytes; Ch

2014