nafamostat has been researched along with Chemical and Drug Induced Liver Injury in 4 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nafamostat mesilate (NM) is a synthetic protease inhibitor with various biological effects." | 1.33 | Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells. ( Choda, Y; Haga, S; Huda, K; Iwagaki, H; Katsuno, G; Miyaso, H; Morimoto, Y; Murata, H; Ozaki, M; Shinoura, S; Takahashi, H; Tanaka, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okada, T | 1 |
| Honda, S | 1 |
| Miyagi, H | 1 |
| Minato, M | 1 |
| Kubota, KC | 1 |
| Taketomi, A | 1 |
| Miyaso, H | 1 |
| Morimoto, Y | 1 |
| Ozaki, M | 1 |
| Haga, S | 1 |
| Shinoura, S | 1 |
| Choda, Y | 1 |
| Murata, H | 1 |
| Katsuno, G | 1 |
| Huda, K | 1 |
| Takahashi, H | 1 |
| Tanaka, N | 1 |
| Iwagaki, H | 1 |
| Ogawa, M | 2 |
| Mori, Y | 2 |
| Ueda, S | 2 |
| Mori, T | 1 |
| Makino, Y | 2 |
| Hori, J | 1 |
| Ohto, M | 2 |
| Wakashin, M | 2 |
| Mor, T | 1 |
| Azemoto, R | 1 |
| Wakashin, Y | 1 |
| Yoshida, H | 1 |
4 other studies available for nafamostat and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Nafamostat mesilate-induced hepatocellular necrosis in a child with pancreatitis caused by pancreaticobiliary maljunction: drug-induced liver injury.
Topics: Benzamidines; Biopsy; Chemical and Drug Induced Liver Injury; Child, Preschool; Cholangiopancreatogr | 2012 |
Protective effects of nafamostat mesilate on liver injury induced by lipopolysaccharide in rats: possible involvement of CD14 and TLR-4 downregulation on Kupffer cells.
Topics: Animals; Benzamidines; Chemical and Drug Induced Liver Injury; Down-Regulation; Guanidines; Hepatocy | 2006 |
Protective effects of FUT-175 on acute massive hepatic necrosis induced in mice following endotoxin injection and immunization with liver proteins.
Topics: Acute Disease; Animals; Autoimmune Diseases; Benzamidines; Chemical and Drug Induced Liver Injury; E | 1993 |
[Effects of FUT-175 on mouse model of acute hepatic necrosis induced by endotoxin following immunological procedure].
Topics: Adjuvants, Immunologic; Animals; Benzamidines; Chemical and Drug Induced Liver Injury; Dose-Response | 1990 |