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nafamostat and Cancer of Liver

nafamostat has been researched along with Cancer of Liver in 6 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Research Excerpts

ExcerptRelevanceReference
"To investigate whether the administration of nafamostat mesilate (NM) reduces the risk of posthepatectomy liver failure (PHLF) in patients undergoing hepatectomy for hepatocellular carcinoma (HCC)."8.12Effect of postoperative administration of nafamostat mesilate on posthepatectomy liver failure. ( Cho, JY; Han, HS; Jo, Y; Kim, M; Lee, B; Lee, HW; Lee, JS; Yoon, YS, 2022)
"Nafamostat mesilate is an anti-inflammatory drug that is usually used to treat pancreatitis."5.43Inhibition of the NF-κB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis. ( Chen, G; Chen, LZ; Ju, HQ; Kang, TB; Lu, YX; Mo, HY; Pan, ZZ; Sheng, H; Wang, F; Wu, QN; Xie, D; Xu, RH; Yun, JP; Zeng, ZL, 2016)
"To investigate whether the administration of nafamostat mesilate (NM) reduces the risk of posthepatectomy liver failure (PHLF) in patients undergoing hepatectomy for hepatocellular carcinoma (HCC)."4.12Effect of postoperative administration of nafamostat mesilate on posthepatectomy liver failure. ( Cho, JY; Han, HS; Jo, Y; Kim, M; Lee, B; Lee, HW; Lee, JS; Yoon, YS, 2022)
"The effect of nafamostat mesilate on coagulation and fibrinolysis was investigated in a study of 22 patients with hepatocellular carcinoma who underwent a hepatic resection."3.69Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection. ( Kamakura, T; Matsumata, T; Shimada, M; Shirabe, K; Sugimachi, K; Taketomi, A, 1994)
" Nafamostat mesilate (FUT-175), a synthetic serine protease inhibitor, inhibited liver metastasis in a CDF1 mice model with colon 26 adenocarcinoma cells."3.68Inhibitory effect of nafamostat mesilate on metastasis into the livers of mice and on invasion of the extracellular matrix by cancer cells. ( Fuchimoto, S; Hizuta, A; Iwagaki, H; Kimura, T; Orita, K, 1992)
"Nafamostat mesilate is an anti-inflammatory drug that is usually used to treat pancreatitis."1.43Inhibition of the NF-κB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis. ( Chen, G; Chen, LZ; Ju, HQ; Kang, TB; Lu, YX; Mo, HY; Pan, ZZ; Sheng, H; Wang, F; Wu, QN; Xie, D; Xu, RH; Yun, JP; Zeng, ZL, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Lee, B1
Cho, JY1
Han, HS1
Yoon, YS1
Lee, HW1
Lee, JS1
Kim, M1
Jo, Y1
Saito, N1
Uwagawa, T1
Hamura, R1
Takada, N1
Sugano, H1
Shirai, Y1
Shiba, H1
Ohashi, T1
Yanaga, K1
Lu, YX1
Ju, HQ1
Wang, F1
Chen, LZ1
Wu, QN1
Sheng, H1
Mo, HY1
Pan, ZZ1
Xie, D1
Kang, TB1
Chen, G1
Yun, JP1
Zeng, ZL1
Xu, RH1
Shimada, M1
Matsumata, T1
Shirabe, K1
Kamakura, T1
Taketomi, A1
Sugimachi, K1
Suzuki, H1
Nimura, Y1
Kamiya, J1
Kondo, S1
Nagino, M1
Kanai, M1
Miyachi, M1
Kimura, T1
Fuchimoto, S1
Iwagaki, H1
Hizuta, A1
Orita, K1

Reviews

1 review available for nafamostat and Cancer of Liver

ArticleYear
Preoperative transcatheter arterial embolization for giant cavernous hemangioma of the liver with consumption coagulopathy.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:4

    Topics: Adult; Anticoagulants; Benzamidines; Combined Modality Therapy; Disseminated Intravascular Coagulati

1997

Other Studies

5 other studies available for nafamostat and Cancer of Liver

ArticleYear
Effect of postoperative administration of nafamostat mesilate on posthepatectomy liver failure.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2022, Volume: 24, Issue:9

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Benzamidines; Bilirubin; Carcinoma, Hepatocellula

2022
Prevention of early liver metastasis after pancreatectomy by perioperative administration of a nuclear factor-κB inhibitor in mice.
    Surgery, 2019, Volume: 166, Issue:6

    Topics: Animals; Benzamidines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal;

2019
Inhibition of the NF-κB pathway by nafamostat mesilate suppresses colorectal cancer growth and metastasis.
    Cancer letters, 2016, 09-28, Volume: 380, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamidines; Cell Movement; Cel

2016
Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection.
    Journal of the American College of Surgeons, 1994, Volume: 178, Issue:5

    Topics: Aged; Antifibrinolytic Agents; Benzamidines; Blood Coagulation; Blood Loss, Surgical; Carcinoma, Hep

1994
Inhibitory effect of nafamostat mesilate on metastasis into the livers of mice and on invasion of the extracellular matrix by cancer cells.
    The Journal of international medical research, 1992, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antithrombins; Benzamidines; Colonic Neoplasms; Extr

1992