Page last updated: 2024-10-31

nafamostat and Burns

nafamostat has been researched along with Burns in 3 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"The systemic effects of epidermal growth factor (EGF) ointment containing nafamostat (NM), gabexate, or gelatin was studied in rats with burns or open wounds."7.68Systemic effects of epidermal growth factor (EGF) ointment containing protease inhibitor or gelatin in rats with burns or open wounds. ( Fuwa, T; Iwakawa, S; Kiyohara, Y; Komada, F; Okumura, K, 1993)
"When epidermal growth factor (EGF) ointment containing a protease inhibitor, nafamostat (NM), was applied to burn sites in rats, the superoxide dismutase (SOD) enzyme activity and protein content increased 45% and 60%, respectively, at these sites 1 d after the burns compared with the control ointment."3.68Cytoprotective effects of epidermal growth factor (EGF) ointment containing nafamostat, a protease inhibitor, on tissue damage at burn sites in rats. ( Hirai, M; Iwakawa, S; Kiyohara, Y; Komada, F; Nishiguchi, K; Okumura, K, 1993)
"The systemic effects of epidermal growth factor (EGF) ointment containing nafamostat (NM), gabexate, or gelatin was studied in rats with burns or open wounds."3.68Systemic effects of epidermal growth factor (EGF) ointment containing protease inhibitor or gelatin in rats with burns or open wounds. ( Fuwa, T; Iwakawa, S; Kiyohara, Y; Komada, F; Okumura, K, 1993)
" No improvement in wound healing was found on topical application of EGF alone to burn sites, but an ointment containing EGF and nafamostat mesilate (NM), a protease inhibitor, accelerated the healing rate of burns."3.68Improvement in wound healing by epidermal growth factor (EGF) ointment. II. Effect of protease inhibitor, nafamostat, on stabilization and efficacy of EGF in burn. ( Fuwa, T; Hirai, M; Iwakawa, S; Kiyohara, Y; Komada, F; Okumura, K, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kiyohara, Y3
Nishiguchi, K1
Komada, F3
Iwakawa, S3
Hirai, M2
Okumura, K3
Fuwa, T2

Other Studies

3 other studies available for nafamostat and Burns

ArticleYear
Cytoprotective effects of epidermal growth factor (EGF) ointment containing nafamostat, a protease inhibitor, on tissue damage at burn sites in rats.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:11

    Topics: Animals; Benzamidines; Blotting, Northern; Burns; Drug Combinations; Epidermal Growth Factor; Guanid

1993
Systemic effects of epidermal growth factor (EGF) ointment containing protease inhibitor or gelatin in rats with burns or open wounds.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:1

    Topics: Animals; Aspartate Aminotransferases; Benzamidines; Body Weight; Burns; Drug Interactions; Drug Syne

1993
Improvement in wound healing by epidermal growth factor (EGF) ointment. II. Effect of protease inhibitor, nafamostat, on stabilization and efficacy of EGF in burn.
    Journal of pharmacobio-dynamics, 1991, Volume: 14, Issue:1

    Topics: Animals; Benzamidines; Burns; Drug Interactions; Drug Stability; Drug Therapy, Combination; Epiderma

1991