nafamostat has been researched along with Brain Injuries in 3 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to evaluate the effects of nafamostat, a serin protease inhibitor, in the management of subarachnoid hemorrhage (SAH)." | 8.12 | Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice. ( Egashira, Y; Enomoto, Y; Hara, H; Imai, T; Iwama, T; Matsubara, H; Nakamura, S; Nakayama, N; Oka, N; Shimazawa, M; Tsuji, S, 2022) |
| "This study aimed to evaluate the effects of nafamostat, a serin protease inhibitor, in the management of subarachnoid hemorrhage (SAH)." | 4.12 | Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice. ( Egashira, Y; Enomoto, Y; Hara, H; Imai, T; Iwama, T; Matsubara, H; Nakamura, S; Nakayama, N; Oka, N; Shimazawa, M; Tsuji, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Matsubara, H | 1 |
| Imai, T | 1 |
| Tsuji, S | 1 |
| Oka, N | 1 |
| Egashira, Y | 1 |
| Enomoto, Y | 1 |
| Nakayama, N | 1 |
| Nakamura, S | 1 |
| Shimazawa, M | 1 |
| Iwama, T | 1 |
| Hara, H | 1 |
| Kwon, SK | 1 |
| Ahn, M | 1 |
| Song, HJ | 1 |
| Kang, SK | 1 |
| Jung, SB | 1 |
| Harsha, N | 1 |
| Jee, S | 1 |
| Moon, JY | 1 |
| Suh, KS | 1 |
| Lee, SD | 1 |
| Jeon, BH | 1 |
| Kim, DW | 1 |
| Kim, CS | 1 |
| Nakamura, T | 1 |
| Kuroda, Y | 1 |
| Hosomi, N | 1 |
| Okabe, N | 1 |
| Kawai, N | 1 |
| Tamiya, T | 1 |
| Xi, G | 1 |
| Keep, RF | 1 |
| Itano, T | 1 |
3 other studies available for nafamostat and Brain Injuries
| Article | Year |
|---|---|
Nafamostat protects against early brain injury after subarachnoid hemorrhage in mice.
Topics: Animals; Benzamidines; Brain; Brain Injuries; Cells, Cultured; Cerebrovascular Circulation; Disease | 2022 |
Nafamostat mesilate attenuates transient focal ischemia/reperfusion-induced brain injury via the inhibition of endoplasmic reticulum stress.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Benzamidines; Br | 2015 |
Serine protease inhibitor attenuates intracerebral hemorrhage-induced brain injury and edema formation in rat.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Basal Ganglia; Benzamidines; Brain Edema; Brain Injuries; Cere | 2010 |