nafamostat has been researched along with Blood Loss, Surgical in 4 studies
nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic
Blood Loss, Surgical: Loss of blood during a surgical procedure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of nafamostat mesilate on coagulation and fibrinolysis was investigated in a study of 22 patients with hepatocellular carcinoma who underwent a hepatic resection." | 3.69 | Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection. ( Kamakura, T; Matsumata, T; Shimada, M; Shirabe, K; Sugimachi, K; Taketomi, A, 1994) |
| "Nafamostat mesilate (NM) is a guanidine acid derivative which is synthesized in Japan as an antifibrinolytic drug." | 2.71 | Influence of heparin dosage on hemostasis under combined use of Nafamostat mesilate during deep hypothermic circulatory arrest. ( Matsuyama, M; Nakamura, K; Niina, K; Onitsuka, T; Yano, M; Yano, Y, 2003) |
| " FUT-175 significantly reduced heparin dosage and 24-hour postoperative blood loss (19,200 +/- 3200 versus 29,100 +/- 7700 IU, P < ." | 2.67 | Nafamostat mesilate reduces blood loss during open heart surgery. ( Abe, T; Koyama, T; Maeda, M; Murase, M; Tomita, Y; Usui, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, K | 1 |
| Onitsuka, T | 1 |
| Yano, M | 1 |
| Yano, Y | 1 |
| Matsuyama, M | 1 |
| Niina, K | 1 |
| Pereboom, IT | 1 |
| de Boer, MT | 1 |
| Porte, RJ | 1 |
| Molenaar, IQ | 1 |
| Shimada, M | 1 |
| Matsumata, T | 1 |
| Shirabe, K | 1 |
| Kamakura, T | 1 |
| Taketomi, A | 1 |
| Sugimachi, K | 1 |
| Murase, M | 1 |
| Usui, A | 1 |
| Tomita, Y | 1 |
| Maeda, M | 1 |
| Koyama, T | 1 |
| Abe, T | 1 |
1 review available for nafamostat and Blood Loss, Surgical
| Article | Year |
|---|---|
Aprotinin and nafamostat mesilate in liver surgery: effect on blood loss.
Topics: Anticoagulants; Aprotinin; Benzamidines; Blood Loss, Surgical; Drug Therapy, Combination; Guanidines | 2007 |
2 trials available for nafamostat and Blood Loss, Surgical
| Article | Year |
|---|---|
Influence of heparin dosage on hemostasis under combined use of Nafamostat mesilate during deep hypothermic circulatory arrest.
Topics: Aged; Anticoagulants; Antifibrinolytic Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Benzamidi | 2003 |
Nafamostat mesilate reduces blood loss during open heart surgery.
Topics: Benzamidines; Blood Loss, Surgical; Blood Transfusion; Cardiopulmonary Bypass; Coronary Artery Bypas | 1993 |
1 other study available for nafamostat and Blood Loss, Surgical
| Article | Year |
|---|---|
Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection.
Topics: Aged; Antifibrinolytic Agents; Benzamidines; Blood Coagulation; Blood Loss, Surgical; Carcinoma, Hep | 1994 |