Page last updated: 2024-10-31

nafamostat and Biliary Atresia

nafamostat has been researched along with Biliary Atresia in 1 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Biliary Atresia: Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.

Research Excerpts

ExcerptRelevanceReference
"In infants with biliary atresia, hepatic Granzymes A and B mRNA, but not Perforin, increased at the time of portoenterostomy."1.40Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia. ( Bezerra, JA; Mourya, R; Shivakumar, P, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shivakumar, P1
Mourya, R1
Bezerra, JA1

Other Studies

1 other study available for nafamostat and Biliary Atresia

ArticleYear
Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia.
    Journal of hepatology, 2014, Volume: 60, Issue:2

    Topics: Animals; Animals, Newborn; Benzamidines; Bile Ducts; Biliary Atresia; CD8-Positive T-Lymphocytes; Ch

2014