Page last updated: 2024-10-31

nafamostat and Anaphylactic Reaction

nafamostat has been researched along with Anaphylactic Reaction in 6 studies

nafamostat: inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic

Research Excerpts

ExcerptRelevanceReference
"Nafamostat is an approved short-acting serine protease inhibitor."1.72Nafamostat is a Potent Human Diamine Oxidase Inhibitor Possibly Augmenting Hypersensitivity Reactions during Nafamostat Administration. ( Alix, M; Boehm, T; Borth, N; Gludovacz, E; Jilma, B; Petroczi, K; Salminen, TA; Vakal, S, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Boehm, T1
Alix, M1
Petroczi, K1
Vakal, S1
Gludovacz, E1
Borth, N1
Salminen, TA1
Jilma, B1
Ookawara, S1
Ito, K1
Morishita, Y1
Sendo, T1
Sumimura, T1
Itoh, Y1
Goromaru, T1
Aki, K1
Yano, T1
Oike, M1
Ito, Y1
Mori, S1
Nishibori, M1
Oishi, R1
Maruyama, H1
Miyakawa, Y1
Gejyo, F2
Arakawa, M1
Higuchi, N1
Yamazaki, H1
Kikuchi, H1
Nagai, H1
Yakuo, I1
Inagaki, N1
Koda, A1
Hamano, S1
Ujiie, A1
Nakazawa, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketotifen as a Treatment for Vascular Leakage During Dengue Fever (KETODEN)[NCT02673840]Phase 4110 participants (Anticipated)Interventional2015-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for nafamostat and Anaphylactic Reaction

ArticleYear
Nafamostat is a Potent Human Diamine Oxidase Inhibitor Possibly Augmenting Hypersensitivity Reactions during Nafamostat Administration.
    The Journal of pharmacology and experimental therapeutics, 2022, Volume: 382, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Anaphylaxis; Benzamidines; Diminazene; Edetic Acid; Guanidines; H

2022
Sustained Deterioration of Hepatic Oxygenation After Nafamostat Mesilate-Induced Anaphylactic Shock During Hemodiafiltration.
    Artificial organs, 2018, Volume: 42, Issue:6

    Topics: Aged; Anaphylaxis; Anticoagulants; Benzamidines; Brain; Guanidines; Hemodiafiltration; Humans; Liver

2018
Involvement of proteinase-activated receptor-2 in mast cell tryptase-induced barrier dysfunction in bovine aortic endothelial cells.
    Cellular signalling, 2003, Volume: 15, Issue:8

    Topics: Actins; Anaphylaxis; Animals; Antigens, CD; Aorta; Benzamidines; Cadherins; Calcium Signaling; Capil

2003
Anaphylactoid reaction induced by nafamostat mesilate in a hemodialysis patient.
    Nephron, 1996, Volume: 74, Issue:2

    Topics: Anaphylaxis; Anticoagulants; Benzamidines; Equipment Failure; Female; Guanidines; Humans; Kidney Fai

1996
Anaphylactoid reaction induced by a protease inhibitor, nafamostat mesilate, following nine administrations in a hemodialysis patient.
    Nephron, 2000, Volume: 86, Issue:3

    Topics: Aged; Anaphylaxis; Benzamidines; Guanidines; Humans; Kidney Failure, Chronic; Male; Protease Inhibit

2000
Role of thromboxane (Tx) A2 in guinea pig Forssman shock and the effect of OKY-046, Tx A2 synthetase inhibitor.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 26, Issue:2

    Topics: Acrylates; Airway Resistance; Anaphylaxis; Animals; Benzamidines; Female; Forssman Antigen; Guanidin

1987