Page last updated: 2024-08-17

nadp and Pancreatic Neoplasms

nadp has been researched along with Pancreatic Neoplasms in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's4 (26.67)29.6817
2010's5 (33.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Boutros, PC; Brown, KR; Chung, S; Dhavarasa, P; Dvorkin-Gheva, A; Hedley, D; Jain, P; Jang, GH; Jessa, F; Koritzinsky, M; Malbeteau, L; Moffat, J; Mollen, E; Notta, F; Vora, P; Wouters, BG; Xie, M1
Fang, J; Guo, D; Jiang, Y; Li, L; Li, M; Liang, J; Lin, SH; Lu, Z; Ma, C; Shao, F; Tong, Y; Yang, D; Yu, Q; Yu, R1
Shang, H; Sun, L; Wu, Y; Xin, X1
Asara, JM; Blenis, J; Dephoure, N; Gomes, AP; Low, V; McReynolds, MR; Piskounova, E; Rabinowitz, JD; Schaffer, BE; Schild, T; Shea, C1
Cantley, LC; Kimmelman, AC; Lyssiotis, CA; Son, J1
Cheng, JK; Gao, X; Huang, X; Lei, QY; Liu, YB; Wang, J; Wang, TS; Wang, YP; Xu, YY; Zhou, W; Zou, SW; Zuo, Y1
Achreja, A; Baddour, J; Chang, E; Chen, A; DePinho, RA; Dey, P; Draetta, G; Fleming, J; Genovese, G; Gutschner, T; Kang, Y; Lan, Z; Lee, J; Liao, WT; Maitra, A; Muller, F; Nagrath, D; Satani, N; Viale, A; Wang, H; Wang, YA; Wu, CC; Yang, L; Ying, H; Zhao, D1
Achreja, A; Chen, G; Chiao, PJ; DePinho, RA; Fu, J; Huang, P; Hung, MC; Ju, HQ; Ling, J; Lu, Y; Nagrath, D; Tian, T; Wang, H; Wu, M; Xu, RH; Yang, L; Yao, J; Ying, H; Zhuang, Z1
Binker, MG; Binker-Cosen, AA; Cosen-Binker, LI; Oliver, B; Richards, D1
Binker, MG; Binker-Cosen, AA; Cosen-Binker, LI; de Cosen, RH; Gaisano, HY; Richards, D1
Chaffard, G; Maechler, P; Merglen, A; Rubi, B; Theander, S; Wollheim, CB1
Asbury, CR; Aykin-Burns, N; Coleman, MC; Cullen, JJ; Daniels, D; Du, J; Li, L; Smith, BJ; Spitz, DR1
Ashford, ML; Hales, CN; Reale, V1
Chen, SC; Kolar, C; Lawson, TA; Mirvish, SS; Wang, X; Zhou, L1
Blachier, F; Malaisse, WJ; Sener, A1

Other Studies

15 other study(ies) available for nadp and Pancreatic Neoplasms

ArticleYear
NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4.
    Science advances, 2021, Volume: 7, Issue:19

    Topics: Endoplasmic Reticulum; Humans; Hydrogen Peroxide; NADP; NADPH Oxidase 4; Oxidation-Reduction; Pancreatic Neoplasms; Peroxiredoxins; Reactive Oxygen Species

2021
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells.
    Molecular cell, 2021, 06-03, Volume: 81, Issue:11

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Glutathione; Heterografts; Humans; Male; Mice; Mice, Nude; NADP; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Prognosis; Protein Processing, Post-Translational; Signal Transduction; Succinate-CoA Ligases; Succinic Acid; Survival Analysis

2021
Hypericin-mediated photodynamic therapy enhances gemcitabine induced Capan-2 cell apoptosis via inhibiting NADPH level.
    The Journal of pharmacy and pharmacology, 2022, Apr-20, Volume: 74, Issue:4

    Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabine; Humans; NADP; Pancreatic Neoplasms; Perylene; Photochemotherapy; Reactive Oxygen Species

2022
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma.
    Cell reports, 2021, 06-15, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Animals; Biosynthetic Pathways; Carcinogenesis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Female; HEK293 Cells; Humans; Male; Mice, Inbred C57BL; Mice, Nude; NADP; Pancreatic Neoplasms; Phosphorylation; Phosphoserine; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Proto-Oncogene Proteins p21(ras); Signal Transduction

2021
Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance.
    Cell cycle (Georgetown, Tex.), 2013, Jul-01, Volume: 12, Issue:13

    Topics: Cell Proliferation; Glutamine; Humans; Metabolic Networks and Pathways; NADP; Oxidation-Reduction; Pancreatic Neoplasms

2013
Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer.
    Molecular cell, 2016, 11-17, Volume: 64, Issue:4

    Topics: Arginine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutamine; HEK293 Cells; Humans; Malate Dehydrogenase (NADP+); Methylation; Mitochondria; Models, Molecular; NADP; Oxidation-Reduction; Pancreatic Neoplasms; Protein Multimerization; Protein Structure, Secondary; Protein-Arginine N-Methyltransferases; RNA, Small Interfering; Signal Transduction

2016
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer.
    Nature, 2017, 02-02, Volume: 542, Issue:7639

    Topics: Amino Acids, Branched-Chain; AMP-Activated Protein Kinases; Animals; Biocatalysis; Carcinoma, Pancreatic Ductal; Gene Deletion; Humans; Ketoglutaric Acids; Malate Dehydrogenase; Male; Mice; Minor Histocompatibility Antigens; Mitochondria; NADP; Pancreatic Neoplasms; Pregnancy Proteins; Reactive Oxygen Species; Sterol Regulatory Element Binding Protein 1; Transaminases

2017
Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
    Nature communications, 2017, 02-24, Volume: 8

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Assays; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NADP; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Oxidation-Reduction; Pancreas; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Signal Transduction; Up-Regulation; Xenograft Model Antitumor Assays

2017
EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2.
    Biochemical and biophysical research communications, 2009, Feb-06, Volume: 379, Issue:2

    Topics: Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; NADP; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; rac1 GTP-Binding Protein; Reactive Oxygen Species; src-Family Kinases

2009
Hypoxia-reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2.
    Biochemical and biophysical research communications, 2010, Mar-12, Volume: 393, Issue:3

    Topics: Cell Hypoxia; Cell Line, Tumor; Humans; Matrix Metalloproteinase 2; NADP; Neoplasm Invasiveness; Oxygen; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; rac1 GTP-Binding Protein; Reactive Oxygen Species

2010
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cell Division; Cytosol; Diazoxide; Electric Conductivity; Electrophysiology; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Membrane Potentials; Mitochondria; NADP; Pancreatic Neoplasms; Patch-Clamp Techniques; Potassium Chloride; Rats; Tolbutamide; Tumor Cells, Cultured

2004
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer.
    Free radical biology & medicine, 2008, Feb-01, Volume: 44, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxyglucose; Free Radical Scavengers; Glucose; Humans; Mice; Mice, Inbred Strains; NADP; Oxidative Stress; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Sulfhydryl Compounds

2008
The effects of pyridine nucleotides on the activity of a calcium-activated nonselective cation channel in the rat insulinoma cell line, CRI-G1.
    The Journal of membrane biology, 1994, Volume: 142, Issue:3

    Topics: Animals; Calcium; Insulinoma; Ion Channels; Islets of Langerhans; Kinetics; Membrane Potentials; NAD; NADP; Pancreatic Neoplasms; Patch-Clamp Techniques; Rats; Tumor Cells, Cultured

1994
Metabolism of the hamster pancreatic carcinogen methyl-2-oxopropylnitrosamine by hamster liver and pancreas.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 2000, Volume: 27, Issue:2

    Topics: Animals; Carcinogens; Cricetinae; Cytosol; In Vitro Techniques; Liver; Male; Mesocricetus; Microsomes, Liver; NAD; NADP; Nitrosamines; Pancreas; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley

2000
Crabtree effect in tumoral pancreatic islet cells.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured

1988