nadp has been researched along with Neoplasms in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (18.57) | 18.7374 |
| 1990's | 7 (5.00) | 18.2507 |
| 2000's | 12 (8.57) | 29.6817 |
| 2010's | 53 (37.86) | 24.3611 |
| 2020's | 42 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bēma, D; Bērziņš, J; Buiķis, I; Freivalds, T; Harju, L; Miķelsone, I; Patetko, L; Simsone, Z | 1 |
| Liang, B; Zhou, D | 1 |
| Gao, W; Han, X; Huang, L; Ji, H; Li, X; Liu, C; Wang, J; Wang, W; Zhang, X | 1 |
| Dudenkova, VV; Gavrina, AI; Kovaleva, TF; Lukyanov, KA; Mozherov, AM; Shcheslavskiy, VI; Shirmanova, MV; Snopova, LB; Zagaynova, EV; Zelenova, EE | 1 |
| Izosimova, AV; Mozherov, AM; Sachkova, DA; Sharonov, GV; Shcheslavskiy, VI; Shirmanova, MV; Yuzhakova, DV; Zagaynova, EV | 1 |
| Jiang, C; Liu, J; Lu, L; Sun, W; Sun, Z; Yu, B; Zhang, Q | 1 |
| Ai, Y; Ding, M; Guan, L; He, MQ; Hu, W; Liang, Q; Ma, C; Sun, H; Zuo, H | 1 |
| Li, Y; Liu, M; Wang, Z; Zhao, Y; Zheng, Y | 1 |
| Chen, H; Gao, L; Li, L; Ma, H; Qiao, R; Wang, Y; Wei, M; Zhang, J; Zhang, X | 1 |
| Connell, CM; Davidson, EE; Ferrer, M; Flint, TR; Gao, Q; Goncalves, MD; Habel, J; Janowitz, T; Kleeman, SO; Lukey, MJ; Mourikis, N; Rubino, R; Venkitaraman, AR; White, EP; Young, L; Zaccaria, M | 1 |
| Cheng, A; Guo, H; Guo, J; Liu, L; Pan, X; Shi, J; Wang, T; Wang, Y; Xu, T; Yang, Z; Yao, X; You, W; Zhang, D; Zhang, H; Zhang, K | 1 |
| Heßling, LD; Troost-Kind, B; Weiß, M | 1 |
| Han, S; Jang, H; Kang, JH; Kang, M; Kang, SW; Kim, SY; Lee, H; Seong, DY; Sim, IA | 1 |
| Chen, H; Ding, Y; Hou, T; Hu, PH; Huang, MS; Li, J; Li, W; Luo, ZJ; Shen, ZT; Shu, C; Wang, B; Wang, FM; Xia, XH; Yuan, S; Zhang, S; Zhao, YH | 1 |
| Gleadle, JM; MacGregor, MN; McNicholas, K | 1 |
| Chiu, DT; Hwang, TL; Liu, HY; Stern, A; Wu, YH; Yang, HC; Yen, WC | 1 |
| Delfarah, A; Graham, NA; Joly, JH; Parrish, S; Phung, PS | 1 |
| Adem, Ş; Asrar, M; Hussain, G; Ji, XY; Rasul, A; Sarfraz, I; Sarker, SD; Selamoglu, Z; Shah, MA; Zahoor, AF | 1 |
| Croft, T; Lin, SJ; Venkatakrishnan, P | 1 |
| Ghareeb, H; Metanis, N | 1 |
| Bertino, JR; Herman, H; Lestari, K; Pramono, AA; Rather, GM | 1 |
| Dinkova-Kostova, AT; Hayes, JD; Tew, KD | 1 |
| Chao, H; Chen, Y; Ji, L; Kuang, S; Liao, X; Rees, TW; Sun, L; Zeng, L; Zhang, X | 1 |
| Cadoux-Hudson, T; Liu, S; Schofield, CJ | 1 |
| Zang, W; Zheng, X | 1 |
| Ju, HQ; Lin, JF; Tian, T; Xie, D; Xu, RH | 1 |
| Gao, W; Huang, C; Huber, PE; Li, C; Shen, G; Xie, N; Zhang, L; Zhou, X; Zou, B | 1 |
| Chiu, DT; Stern, A; Yang, HC | 1 |
| Duan, D; Fang, J; Osama, A; Zhang, J | 1 |
| Gu, C; Li, R; Wang, W; Yang, Y | 1 |
| Dai, P; Deng, J; Fan, A; Guo, X; Li, Z; Liu, F; Qin, Y; Wang, B; Wang, Z; Zhao, Y | 1 |
| Bauckneht, M; Bonanomi, M; Bruno, S; Cossu, V; Gaglio, D; Marini, C; Miceli, A; Morbelli, S; Orengo, AM; Piccioli, P; Ravera, S; Righi, N; Sambuceti, G | 1 |
| Cai, N; Cheng, K; Liang, H; Wen, J; Xiong, Y; Zhang, W; Zhang, Y; Zhu, J | 1 |
| Boothman, DA; Forshaw, TE; Furdui, CM; Kemp, ML; Lewis, JE | 1 |
| Jiang, WL; Li, CY; Li, Y; Mao, GJ; Tian, Y; Wang, WX | 1 |
| Chen, D; Duan, C; Liu, HX; Liu, X; Liu, Y; Piao, HL; Qi, H; Wang, Y; Xia, T | 1 |
| Bertino, JR; Pramono, AA; Rather, GM; Szekely, Z; Tedeschi, PM | 1 |
| Banerjee, S | 1 |
| Bai, R; Chen, C; Du, P; Gao, F; Li, J; Liu, J; Liu, S; Liu, T; Lu, X; Ma, M; Qin, F; Wang, Y; Zhou, H | 1 |
| Pei, DS; Xie, M | 1 |
| Hu, CA | 1 |
| Cai, L; Hu, X; Ying, M; You, D; Zeng, S; Zhu, X | 1 |
| Bauckneht, M; Bruno, S; Cossu, V; Lanfranchi, F; Marini, C; Orengo, AM; Raffa, S; Ravera, S; Sambuceti, G | 1 |
| Anselmo, SL; Avellaneda Matteo, D; Gonzalez, ER; Grunseth, AJ; Hoang, A; Kennedy, MA; Moman, P; Scott, DA; Sohl, CD | 1 |
| Maddocks, ODK; Newman, AC | 1 |
| Cheng, ML; Ho, HY; Lin, G; Lin, YT; Wu, PR | 1 |
| Chen, T; Du, W; Jiang, P; Sun, H; Xu, C; Yao, P; Zou, B | 1 |
| Alam, SR; Hu, S; Kashatus, D; Periasamy, A; Siller, KH; Svindrych, Z; Wallrabe, H; Wang, T | 1 |
| Chapman, S; DeBerardinis, RJ; Fagan, P; Gorsuch, CL; Hamann, JC; Hawk, MA; Hu, S; Jiang, L; Kim, SE; Lee, C; Leevy, WM; Mason, JA; Overholtzer, M; Schafer, ZT; Shen, L; Shuff, S; Tsegaye, MA; Weigel, KJ; Zuo, J | 1 |
| Druzhkova, IN; Dudenkova, VV; Ignatova, NI; Lukina, MM; Shimolina, LE; Shirmanova, MV; Zagaynova, EV | 1 |
| Deng, H; Leadlay, PF; Lin, HW; Lin, X; Liu, L; Shen, Y; Sun, F; Wang, SP; Williams, SR; Xu, S; Zhou, Y | 1 |
| Dean, AE; Gius, D; Heer, C; Horikoshi, N; Spitz, DR; Zhu, Y | 1 |
| Dasgupta, T; Dexter, JP; Gunawardena, J; Hosios, AM; Vander Heiden, MG; Ward, PS | 1 |
| Becherini, P; Bruzzone, S; Caffa, I; Cea, M; Damonte, P; Fresia, C; Garten, A; Grozio, A; Kiess, W; Mazzola, F; Nencioni, A; Passalacqua, M; Raffaelli, N; Schuster, S; Sociali, G; Sturla, L | 1 |
| Hou, W; Lin, C; Lu, S; Ruan, BH; Su, L; Xu, H; Yu, B; Yu, Y; Zhao, H | 1 |
| Gao, H; Li, W; Liang, J; Liu, R; Tao, B; Wang, C; Wang, X; Yang, W; Yang, Z; Zhang, Y | 1 |
| Aguiar, M; Arellano, M; Blum, WG; Boggon, TJ; Brennan, CW; Chen, D; Chen, J; Famulare, CA; Fan, J; Gao, X; Jin, L; Levine, RL; Li, Y; Lin, R; Liu, S; Lonial, S; Mao, H; Mishra, A; Mukherjee, J; Pan, Y; Peng, J; Pieper, RO; Shih, AH; Song, L; Wang, M; Xia, S; Zhou, A | 1 |
| Kouri, FM; Mahajan, AS; May, JL; Murnan, K; Stegh, AH; Tommasini-Ghelfi, S | 1 |
| Ghahremanloo, A; Hashemy, SI; Javid, H; Mohammadi, F; Soltani, A | 1 |
| Cantley, LC; Carracedo, A; Pandolfi, PP | 1 |
| Icard, P; Lincet, H | 1 |
| Bamezai, RN; Chaman, N; Chattopadhyay, S; Gopinath, P; Gupta, V; Iqbal, MA; Kumar, B; Manvati, S; Siddiqui, FA | 1 |
| Bertino, JR; Boros, LG; Chan, LL; DiPaola, RS; Dolfi, SC; Dvorzhinski, D; Gounder, M; Hirshfield, KM; Lin, H; Markert, EK; Oltvai, ZN; Qiu, J; Tedeschi, PM; Vazquez, A | 1 |
| Choi, EH; Kaushik, N; Kaushik, NK; Park, D | 1 |
| Boruta, RJ; Dewhirst, MW; Fontanella, AN; Guo, J; Hofmann, CL; Landon, C; Manzoor, A; Palmer, GM; Park, JY; Viglianti, BL | 1 |
| Auchinvole, C; Campbell, CJ; Fisher, K; Jiang, J | 1 |
| Alberghina, L; Gaglio, D | 1 |
| Ebert, B; Hintzpeter, J; Hornung, J; Martin, HJ; Maser, E | 1 |
| Gerner, C; Grunt, T; Haider, F; Karlic, H; Proestling, K; Thaler, R; Varga, F | 1 |
| Hachem, A; Lear, P; Parrington, J | 1 |
| Diggins, KE; Irish, JM; Shah, AT; Skala, MC; Walsh, AJ | 1 |
| Hayano, M; Pagano, NC; Shimada, K; Stockwell, BR | 1 |
| Druzhkova, IN; Dudenkova, VV; Lukina, MM; Mishina, NM; Shirmanova, MV; Zagaynova, EV | 1 |
| Adams, ND; DeBerardinis, RJ; Dranka, BP; Jiang, L; McCabe, MT; Metallo, CM; Parker, SJ; Pietrak, B; Schmidt, S; Schwartz, B; Shestov, AA; Swain, P; Terada, LS; Wang, QA; Yang, C | 1 |
| Deng, F; Liu, X; Qu, Q; Wang, QJ; Zeng, F | 1 |
| Atkins, JT; DiNardo, CD; Fujii, T; Janku, F; Khawaja, MR | 1 |
| Del Mazo-Monsalvo, I; Marín-Hernández, Á; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E | 1 |
| Abali, EE; Bansal, N; Bertino, JR; Kerrigan, JE; Scotto, KW; Tedeschi, PM | 1 |
| Bohndiek, SE; Brindle, KM; Dzien, P; Hu, DE; Kennedy, BWC; Kettunen, MI; Larkin, TJ; Marco-Rius, I; Timm, KN; Williams, M; Wright, AJ | 1 |
| Cha, SY; Cha, YH; Cheong, JH; Cho, ES; Hwang, GS; Kang, SW; Kim, HS; Kim, N; Kim, NH; Kim, SY; Lee, J; Lee, SH; Lee, Y; Nam, M; Park, S; Ryu, JK; Yang, JH; Yook, JI; Yuk, YS; Yun, JS; Zhang, X | 1 |
| DeBerardinis, RJ; Vander Heiden, MG | 1 |
| Michelakis, ED; Weir, EK | 1 |
| Ahmad, IM; Aykin-Burns, N; Oberley, LW; Spitz, DR; Zhu, Y | 1 |
| Jakobs, C; Struys, EA; Wamelink, MM | 1 |
| Gastaldello, S; Gruhne, B; Kamranvar, SA; Marescotti, D; Masucci, MG; Sompallae, R | 1 |
| Feron, O | 1 |
| Chandel, NS; Weinberg, F | 1 |
| Bhardwaj, R; Dwarakanath, BS; Sharma, PK; Varshney, R | 1 |
| Reitman, ZJ; Yan, H | 1 |
| Thompson, CB; Wise, DR | 1 |
| Jung, KH; Park, JW | 1 |
| Levine, AJ; Puzio-Kuter, AM | 1 |
| Du, J; King, I; Nassar, AE | 1 |
| Gong, J; Neels, JF; Pietsch, KE; Sturla, SJ; Yu, X | 1 |
| Chandel, NS; Chen, PH; Cheng, T; DeBerardinis, RJ; Jin, ES; Linehan, WM; Mullen, AR; Sullivan, LB; Wheaton, WW; Yang, Y | 1 |
| Jackowski, S; Leonardi, R; Rock, CO; Subramanian, C | 1 |
| Shaw, RJ; Svensson, RU | 1 |
| Chandel, NS; Hay, N; Jeon, SM | 1 |
| Altschmied, J; Haendeler, J; Matsushima, S; Sadoshima, J; Shao, D; Zschauer, TC | 1 |
| Clark, PM; Driggers, EM; Goddard, WA; Hill, C; Hsieh-Wilson, LC; Keenan, MC; Mason, DE; Peters, EC; Yi, W | 1 |
| Ali, SM; Olivo, M | 1 |
| GLOCK, GE; MCLEAN, P | 1 |
| HAWTREY, AO; SILK, MH | 1 |
| WENNER, CE | 2 |
| BURK, D; WOODS, M | 1 |
| NODES, JT; REID, E | 1 |
| MISRA, DK | 1 |
| CLARK, JB; GREENBAUM, AL; MCLEAN, P; REID, E | 1 |
| COLETTA, DF; SIEGEL, PD | 1 |
| Iqbal, M; Okada, S | 1 |
| Dubin, M; Fernández Villamil, S; Stoppani, AO | 1 |
| Aitken, RJ; Baker, MA | 1 |
| Diz, DI; Robbins, ME | 1 |
| Reztsova, VV | 1 |
| Segal, B; Segal, R | 1 |
| Bernofsky, C | 1 |
| Ames, MM; Kovach, JS; Lieber, MM; Powis, G | 1 |
| Amzel, LM; Bianchet, MA; Li, R; Talalay, P | 1 |
| Eskelson, CD; Mufti, SI; Nachiappan, V; Odeleye, OE | 1 |
| Ahorn, H; Dworkin, MB; Infante, A; Loeber, G | 1 |
| Jacobson, EL | 1 |
| Jacobson, EL; Jacobson, MK | 1 |
| Bender, DA | 1 |
| Delides, A; Goldberg, DM; Neal, FE; Spooner, RJ | 1 |
| DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS | 1 |
| Holroyde, CP; Myers, RN; Paul, P; Putnam, RC; Reichard, GA; Smink, RD | 1 |
| Baturay, N; Blanco, DR; Kwon, CH | 1 |
| Phang, JM | 1 |
| MacKenzie, RE; Mejia, N; Yang, XM | 1 |
| Meighen, E; Riendeau, D | 1 |
| Miller, KW; Tu, YY; Wang, T; Yang, CS | 1 |
| Abelson, HT; Dolnick, BJ; Kamen, BA; Nylen, PA; Peterson, DW; Whitehead, VM | 1 |
| Kerppola, W | 1 |
| Heath, HD; Lenhoff, HM; Rutherford, C | 1 |
| Bertino, JR; Cashmore, AR; Hillcoat, BL | 1 |
| Ababei, L; Hăulică, A | 1 |
| Pitout, MJ; Purchase, IF; Steyn, M | 1 |
| Criss, WE | 1 |
55 review(s) available for nadp and Neoplasms
| Article | Year |
|---|---|
p53: A double-edged sword in tumor ferroptosis.
Topics: Apoptosis; Ferroptosis; Humans; Lipid Peroxidation; NADP; Neoplasms; Tumor Suppressor Protein p53 | 2022 |
NAADP-binding proteins - Linking NAADP signaling to cancer and immunity.
Topics: Carrier Proteins; Humans; NADP; Neoplasms; Second Messenger Systems; Signal Transduction | 2023 |
In order for the light to shine so brightly, the darkness must be present-why do cancers fluoresce with 5-aminolaevulinic acid?
Topics: Amino Acid Transport Systems; Aminolevulinic Acid; Brain Neoplasms; Coproporphyrinogens; Ferrochelatase; Fluorescence; Glucose; Heme; Humans; Iron; MicroRNAs; Mitochondria; Mutation; NADP; Neoplasms; Oncogenes; Optical Imaging; Peptide Transporter 1; Photochemotherapy; Protoporphyrins; Skin Neoplasms; Symporters; Tumor Hypoxia; Tumor Microenvironment; Urinary Bladder Neoplasms | 2019 |
The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer.
Topics: Cell Cycle; Cell Death; Cell Proliferation; Cell Survival; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Homeostasis; Humans; NADP; Neoplasms; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species; Signal Transduction | 2019 |
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Topics: Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; NADP; Neoplasms; NF-E2-Related Factor 2; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Processing, Post-Translational; Radiation Tolerance; RNA-Binding Proteins; Signal Transduction; Vesicular Transport Proteins | 2020 |
NAD
Topics: Animals; Fungal Proteins; Homeostasis; Humans; NAD; NADP; Neoplasms; Oxidation-Reduction; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Yeasts | 2020 |
The Thioredoxin System: A Promising Target for Cancer Drug Development.
Topics: Antineoplastic Agents; Drug Development; Humans; NADP; Neoplasms; Oxidation-Reduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 2020 |
NAD- and NADPH-Contributing Enzymes as Therapeutic Targets in Cancer: An Overview.
Topics: Animals; Antineoplastic Agents; Biosynthetic Pathways; Drug Discovery; Enzyme Inhibitors; Humans; Molecular Targeted Therapy; NAD; NADP; Neoplasms; Nicotinamide Phosphoribosyltransferase | 2020 |
Oxidative Stress in Cancer.
Topics: Animals; Antioxidants; Apoptosis; Energy Metabolism; Glucose; Humans; NADP; Neoplasms; Oxidative Stress; Reactive Oxygen Species | 2020 |
Isocitrate dehydrogenase variants in cancer - Cellular consequences and therapeutic opportunities.
Topics: Animals; Enzyme Inhibitors; Glutarates; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Models, Molecular; NADP; Neoplasms | 2020 |
Structure and functions of cellular redox sensor HSCARG/NMRAL1, a linkage among redox status, innate immunity, DNA damage response, and cancer.
Topics: Animals; DNA Damage; Humans; Immunity, Innate; NADP; Neoplasms; NF-kappa B; Oxidation-Reduction; Signal Transduction; Transcription Factors | 2020 |
NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications.
Topics: Animals; Antioxidants; Cellular Reprogramming; Homeostasis; Humans; NADP; Neoplasms; Oxidative Stress | 2020 |
NAD
Topics: Aging; Cyclic ADP-Ribose; Humans; Metabolic Diseases; NAD; NADP; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction | 2020 |
G6PD: A hub for metabolic reprogramming and redox signaling in cancer.
Topics: Glucosephosphate Dehydrogenase; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2021 |
Natural Molecules Targeting Thioredoxin System and Their Therapeutic Potential.
Topics: Carcinogenesis; Homeostasis; Humans; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 2021 |
Exploring the role of glucose‑6‑phosphate dehydrogenase in cancer (Review).
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Erythrocytes; Gene Expression Regulation, Neoplastic; Glucose; Glucosephosphate Dehydrogenase; Glutathione; Humans; Mice; Mutation; NADP; Neoplasms; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2020 |
The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors.
Topics: Acetaminophen; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisinins; Auranofin; Cell Death; Cisplatin; Epigenesis, Genetic; Fatty Acids; Ferroptosis; Haloperidol; Humans; Indoles; Iron; Lapatinib; Mevalonic Acid; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Oxygen; Quinolines; Reactive Oxygen Species; Sorafenib; Spiro Compounds; Sulfasalazine; Trigonella | 2020 |
The double-edged roles of ROS in cancer prevention and therapy.
Topics: Antioxidants; Apoptosis; Carcinogenesis; Cell Proliferation; Epithelial-Mesenchymal Transition; Ferroptosis; Humans; Mitochondria; NADP; NADPH Oxidases; Necroptosis; Neoplasms; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Regulated Cell Death; Signal Transduction; Superoxide Dismutase | 2021 |
In cancer, all roads lead to NADPH.
Topics: Humans; NADP; Neoplasms | 2021 |
Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Catalysis; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Humans; Inflammation; NADP; Neoplasms; Oxidative Stress | 2021 |
Serine hydroxymethyltransferase 2: a novel target for human cancer therapy.
Topics: Cell Proliferation; Deubiquitinating Enzymes; Drug Resistance; Glutathione; Glycine Hydroxymethyltransferase; Humans; Hypoxia; NADP; Neoplasms; Pyruvate Kinase; Sirtuins; STAT3 Transcription Factor | 2021 |
Isozymes of P5C reductase (PYCR) in human diseases: focus on cancer.
Topics: Amino Acid Sequence; Animals; delta-1-Pyrroline-5-Carboxylate Reductase; Humans; Isoenzymes; Mitochondria; NAD; NADP; Neoplasms; Pyrroline Carboxylate Reductases | 2021 |
Metformin and Cancer Glucose Metabolism: At the Bench or at the Bedside?
Topics: AMP-Activated Protein Kinases; Animals; Biomedical Research; Carbohydrate Dehydrogenases; Cell Proliferation; Cytosol; Endoplasmic Reticulum; Fluorodeoxyglucose F18; Glucose; Humans; Hypoglycemic Agents; Metformin; NADP; Neoplasms; Oxidative Phosphorylation; Pentose Phosphate Pathway; Phosphorylation; Positron Emission Tomography Computed Tomography; Reproducibility of Results | 2021 |
One-carbon metabolism in cancer.
Topics: Amino Acids; Carbon; Humans; Metabolic Networks and Pathways; Methylation; NAD; NADP; Neoplasms; Nucleotides | 2017 |
Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy.
Topics: Animals; Female; Gene Expression; Humans; Male; Mitochondria; Mitochondrial Proteins; Models, Biological; NAD; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Protein Transport; Signal Transduction; Sirtuins | 2018 |
Cancer-associated mutation and beyond: The emerging biology of isocitrate dehydrogenases in human disease.
Topics: Allosteric Site; Animals; Catalytic Domain; Citric Acid Cycle; Cytoplasm; DNA Methylation; Epigenesis, Genetic; Glutarates; Homeostasis; Humans; Immune System; Inhibitory Concentration 50; Isocitrate Dehydrogenase; Mice; Mitochondria; Mutation; NADP; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Phenotype | 2019 |
The thioredoxin system and cancer therapy: a review.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Humans; NADP; Neoplasms; Oxidative Stress; Thioredoxin-Disulfide Reductase; Thioredoxins | 2019 |
Cancer metabolism: fatty acid oxidation in the limelight.
Topics: Adenosine Triphosphate; Energy Metabolism; Fatty Acids; Humans; Molecular Targeted Therapy; Mutation; NADP; Neoplasms; Signal Transduction | 2013 |
[The cancer tumor: a metabolic parasite?].
Topics: Amino Acids; Cell Hypoxia; Cell Proliferation; Citric Acid; Glycolysis; Humans; Lipolysis; NADP; Neoplasm Proteins; Neoplasms | 2013 |
Redox control of glutamine utilization in cancer.
Topics: Amino Acids; Antineoplastic Agents; Glutamine; Glycolysis; Humans; Lipids; Mitochondria; Mitochondrial Proteins; NAD; NADP; NADP Transhydrogenase, AB-Specific; Neoplasms; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species | 2014 |
Calcium signals regulated by NAADP and two-pore channels--their role in development, differentiation and cancer.
Topics: Animals; Calcium; Calcium Signaling; Cell Differentiation; Endoplasmic Reticulum; Humans; NADP; Neoplasms; Ryanodine Receptor Calcium Release Channel | 2015 |
Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carnitine; Carnitine O-Palmitoyltransferase; Cytoplasm; Fatty Acids; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Lipid Metabolism; Mitochondria; Molecular Targeted Therapy; NADP; Neoplasms; Oxidation-Reduction | 2016 |
Targeting isocitrate dehydrogenase (IDH) in cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cell Differentiation; Cell Respiration; Cell Transformation, Neoplastic; Clinical Trials as Topic; Glutarates; Histone Demethylases; Histones; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Molecular Targeted Therapy; Mutation; NADP; Neoplasms | 2016 |
NAD+ Kinase as a Therapeutic Target in Cancer.
Topics: Animals; Humans; NAD; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species | 2016 |
Understanding the Intersections between Metabolism and Cancer Biology.
Topics: Adenosine Triphosphate; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Citric Acid Cycle; Humans; Metabolic Networks and Pathways; NADP; Neoplasms; Nucleotides | 2017 |
The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.
Topics: Glycolysis; Humans; Hypoxia; Metabolism, Inborn Errors; Models, Biological; Mutation; NADP; Neoplasms; Oxygen; Pentose Phosphate Pathway; Phenotype; Ribose; Transaldolase | 2008 |
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.
Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Energy Metabolism; Glycolysis; Humans; Lactic Acid; NAD; NADP; Neoplasms; Oxidation-Reduction; Pyruvic Acid; Radiation Tolerance; Sensitivity and Specificity | 2009 |
Mitochondrial metabolism and cancer.
Topics: Adenosine Triphosphate; Animals; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Mitochondria; Models, Biological; NADP; Neoplasms; Reactive Oxygen Species | 2009 |
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
Topics: Animals; Arginine; Brain Neoplasms; Codon; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Glucose; Glutarates; Humans; Hypoxia; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Oligodendroglioma; Oncogenes; Signal Transduction; Up-Regulation | 2010 |
Glutamine addiction: a new therapeutic target in cancer.
Topics: Animals; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; NADP; Neoplasms; Nucleotides; Protein Biosynthesis; TOR Serine-Threonine Kinases | 2010 |
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes.
Topics: Adenosine Triphosphate; Cell Division; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glucose; Glutamine; Glycolysis; Humans; NADP; Neoplasms; Oncogenes; Pentose Phosphate Pathway; Signal Transduction | 2010 |
Interacting with thioredoxin-1--disease or no disease?
Topics: Animals; Atherosclerosis; Blood Vessels; Cardiovascular System; Cysteine; Cystine; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hydrogen Peroxide; Mice; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Peroxiredoxins; Reactive Oxygen Species; Signal Transduction; Thioredoxins | 2013 |
Redox cycling of beta-lapachone and structural analogues in microsomal and cytosol liver preparations.
Topics: Animals; Antineoplastic Agents; Cytosol; Electron Spin Resonance Spectroscopy; Humans; Liver Extracts; Microsomes; Molecular Structure; NADP; NADPH-Ferrihemoprotein Reductase; Naphthoquinones; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species | 2004 |
Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility.
Topics: Acridines; Child; Cytoplasm; Electron Transport; Genetic Diseases, Inborn; Germ-Line Mutation; Humans; Infertility, Male; Luminescence; Male; NAD; NADP; NADPH Oxidases; Neoplasms; Nitric Oxide; Oxidative Stress; Paternal Age; Reactive Oxygen Species; Spermatozoa | 2005 |
Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Brain; Captopril; Humans; Inflammation; Kidney; Lung; NADP; Neoplasms; Oxidative Stress; Radiation Injuries; Radiation Pneumonitis; Reactive Oxygen Species; Renin-Angiotensin System; Survivors | 2006 |
[Role of glycolysis in initiation of immortality and apoptosis].
Topics: Animals; Apoptosis; Cell Survival; DNA Methylation; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hexokinase; Humans; NADP; Neoplasms; Nitric Oxide Synthase; Telomerase | 2006 |
The implications of the oxidation of lipids and anti-oxidizers for sanogenesis.
Topics: Animals; Antioxidants; Arteriosclerosis; Avitaminosis; Diet; Diet, Atherogenic; Food Analysis; Food Preservatives; Food Technology; Glutathione; Guinea Pigs; Humans; Lipid Peroxides; Membrane Lipids; NADP; Neoplasms; Oxidation-Reduction; Rats; Vitamin E | 1983 |
Physiology aspects of pyridine nucleotide regulation in mammals.
Topics: Adrenal Cortex Hormones; Animals; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hyperthyroidism; Hypophysectomy; Liver; Mice; Mitochondria; NAD; NADP; Neoplasms; Niacinamide; Poly Adenosine Diphosphate Ribose; Rats | 1980 |
Alcohol-associated generation of oxygen free radicals and tumor promotion.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Ethanol; Female; Free Radicals; Humans; Iron Chelating Agents; Lipid Peroxidation; Male; Mitochondria, Liver; NADP; Neoplasms; Oxygen; Xanthine Dehydrogenase | 1993 |
Tryptophan and niacin nutrition--is there a problem?
Topics: Adult; Animals; Cognition Disorders; Environmental Exposure; Humans; Hydrolases; Iron Deficiencies; Kynurenine 3-Monooxygenase; Lead Poisoning; Liver; Mixed Function Oxygenases; NAD; NADP; Neoplasms; Niacin; Nutritional Requirements; Oxidative Stress; Trace Elements; Tryptophan; Zinc | 1996 |
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1976 |
The regulatory functions of proline and pyrroline-5-carboxylic acid.
Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship | 1985 |
Enzymatic reduction of fatty acids and acyl-CoAs to long chain aldehydes and alcohols.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Aldehydes; Animals; Bacteria; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Coenzyme A; Coenzyme A Ligases; Fatty Acids; Fatty Alcohols; Hydrogen-Ion Concentration; Kinetics; Microsomes; NAD; NADP; Neoplasms; Oxidation-Reduction; Plants; Repressor Proteins; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thermodynamics; Tissue Distribution | 1985 |
Progress in tumor enzymology.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cholesterol; Diethylstilbestrol; DNA; Enzyme Induction; Enzyme Repression; Feedback; Glycogen; Glycolysis; Hexokinase; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Malate Dehydrogenase; NAD; NADP; Neoplasms; Oxygen; Phosphates; Phosphofructokinase-1 | 1967 |
A review of isozymes in cancer.
Topics: Animals; Aspartate Aminotransferases; Carbamates; Cell Transformation, Neoplastic; DNA Nucleotidyltransferases; Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase; Fructosephosphates; Glutaminase; Glycerolphosphate Dehydrogenase; Hexokinase; Isocitrate Dehydrogenase; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Malate Dehydrogenase; Molecular Weight; NAD; NADP; Neoplasms; Phosphotransferases; Pyruvate Kinase; Transferases | 1971 |
85 other study(ies) available for nadp and Neoplasms
| Article | Year |
|---|---|
Cancer microcell initiation and determination.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Count; Cell Line, Tumor; Cell Nucleus; Cell Self Renewal; Cell Survival; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Endosomal Sorting Complexes Required for Transport; Female; Fibroblasts; Green Fluorescent Proteins; HeLa Cells; Humans; Indicators and Reagents; Melanoma; Microscopy, Electron; NADP; Neoplasm Recurrence, Local; Neoplasms; Neutral Red; Paclitaxel; Stress, Physiological; Time-Lapse Imaging; Transcription Factors; Transfection; Uterine Cervical Neoplasms | 2021 |
ROS-Activated homodimeric podophyllotoxin nanomedicine with self-accelerating drug release for efficient cancer eradication.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Liberation; Drug Stability; Female; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; NAD(P)H Dehydrogenase (Quinone); NADP; Nanoparticles; Neoplasms; Podophyllotoxin; Poloxamer; Polymers; Prodrugs; Reactive Oxygen Species; Tumor Microenvironment; Vitamin K 3; Xenograft Model Antitumor Assays | 2021 |
Insight into redox regulation of apoptosis in cancer cells with multiparametric live-cell microscopy.
Topics: Apoptosis; Caspase 3; Cisplatin; Microscopy, Fluorescence; NAD; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Staurosporine | 2022 |
FLIM of NAD(P)H in Lymphatic Nodes Resolves T-Cell Immune Response to the Tumor.
Topics: Animals; Mice; Microscopy, Fluorescence; NAD; NADP; Neoplasms; T-Lymphocytes | 2022 |
Engineering a synergistic antioxidant inhibition nanoplatform to enhance oxidative damage in tumor treatment.
Topics: Antioxidants; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; NADP; Nanoparticles; Neoplasms; Oxidative Stress; Peroxidases; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Tumor Microenvironment | 2023 |
An NIR fluorescent/photoacoustic dual-mode probe of NADPH for tumor imaging.
Topics: Animals; Fluorescent Dyes; Mice; NADP; Neoplasms; Optical Imaging; Photoacoustic Techniques; Spectrum Analysis | 2023 |
Coenzyme-depleting nanocarriers for enhanced redox cancer therapy under hypoxia.
Topics: Animals; Antioxidants; Cell Line, Tumor; Coenzymes; Glutathione; Humans; Hypoxia; Mice; NADP; Neoplasms; Nitroimidazoles; Oxidation-Reduction; Sorafenib | 2023 |
Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation.
Topics: Cell Proliferation; Humans; NADP; Neoplasms; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Reactive Oxygen Species | 2023 |
Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia.
Topics: Animals; Cachexia; Corticosterone; Diet, Ketogenic; Ferroptosis; Glucose; Interleukin-6; Ketone Bodies; Mice; NADP; Neoplasms | 2023 |
NADPH increase in mitosis in aneuploid tumour cells protects against genomic aberrations.
Topics: Aneuploidy; Genomics; Humans; Mitosis; NADP; Neoplasms | 2023 |
A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Aneuploidy; Apoptosis Regulatory Proteins; Chromosome Segregation; Humans; NADP; Neoplasms; Reactive Oxygen Species | 2023 |
Glucose Deprivation Induces Cancer Cell Death through Failure of ROS Regulation.
Topics: Adenosine Triphosphate; Antioxidants; Cell Death; Glucose; Glutathione; Humans; NADP; Neoplasms; Reactive Oxygen Species | 2023 |
Core-Shell Reactor Partitioning Enzyme and Prodrug by ZIF-8 for NADPH-Sensitive In Situ Prodrug Activation.
Topics: Antineoplastic Agents; Cytochrome P-450 Enzyme System; Dacarbazine; Humans; NADP; Neoplasms; Prodrugs | 2023 |
A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.
Topics: Amino Acid Transport System y+; Antineoplastic Combined Chemotherapy Protocols; Antiporters; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Dimerization; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutathione; Humans; Metabolome; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Synthetic Drugs | 2020 |
A Mitochondrion-Localized Two-Photon Photosensitizer Generating Carbon Radicals Against Hypoxic Tumors.
Topics: Carbon; Cell Hypoxia; Humans; Mitochondria; NADP; Neoplasms; Photochemotherapy; Photons; Photosensitizing Agents; Spectrum Analysis; Tumor Microenvironment | 2020 |
Electron-Accepting Micelles Deplete Reduced Nicotinamide Adenine Dinucleotide Phosphate and Impair Two Antioxidant Cascades for Ferroptosis-Induced Tumor Eradication.
Topics: Animals; Antioxidants; Cell Line, Tumor; Electrons; Ferroptosis; Glutathione; Mice; Micelles; NADP; Neoplasms; Oxidation-Reduction; Phosphates | 2020 |
Two high-rate pentose-phosphate pathways in cancer cells.
Topics: Animals; Chromatography, Liquid; Endoplasmic Reticulum; Energy Metabolism; Gene Silencing; Glucosephosphate Dehydrogenase; Humans; Mass Spectrometry; Metabolomics; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Reactive Oxygen Species | 2020 |
Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors.
Topics: Humans; Hydrogen Peroxide; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species | 2021 |
NAD(P)H-triggered probe for dual-modal imaging during energy metabolism and novel strategy of enhanced photothermal therapy in tumor.
Topics: Animals; Cell Line, Tumor; Energy Metabolism; Mice; NADP; Nanoparticles; Neoplasms; Photoacoustic Techniques; Phototherapy; Photothermal Therapy; Theranostic Nanomedicine | 2021 |
Hypoxia and pH co-triggered oxidative stress amplifier for tumor therapy.
Topics: Acrolein; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Glutathione; Humans; Hydrogen-Ion Concentration; Mice; NADP; Neoplasms; Nitroimidazoles; Oxidative Stress; Reactive Oxygen Species; Tumor Hypoxia; Tumor Microenvironment | 2021 |
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Topics: Animals; Glucose; Glutamine; Lactic Acid; Mice; NADP; Neoplasms; Pentose Phosphate Pathway | 2021 |
Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.
Topics: Catalysis; Catalytic Domain; Circular Dichroism; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Glioma; Humans; Hydrophobic and Hydrophilic Interactions; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Oxygen; Protein Engineering; Protein Multimerization; Software; Temperature | 2017 |
Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; Glycolysis; Histone Deacetylase 1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mitochondria; Mitochondrial Proteins; NAD; NADP; NADP Transhydrogenase, AB-Specific; Neoplasm Transplantation; Neoplasms; Oxidative Phosphorylation; Signal Transduction | 2017 |
Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Topics: Cell Line, Tumor; Gluconates; Humans; Hydro-Lyases; Malate Dehydrogenase; Mutation, Missense; NADP; Neoplasm Proteins; Neoplasms; Pentose Phosphate Pathway; Protein Multimerization; Signal Transduction | 2017 |
Segmented cell analyses to measure redox states of autofluorescent NAD(P)H, FAD & Trp in cancer cells by FLIM.
Topics: Animals; Cytosol; Disease Models, Animal; Doxorubicin; Flavin-Adenine Dinucleotide; Glucose; Heterografts; Humans; Microscopy, Fluorescence; Mitochondria; Molecular Imaging; NAD; NADP; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation | 2018 |
RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Epithelial Cells; Extracellular Matrix; Female; HCT116 Cells; HeLa Cells; Humans; Mammary Glands, Human; Mice, Nude; Mitochondria; Mitochondrial Proteins; Mitophagy; NADP; Neoplasm Metastasis; Neoplasms; Phosphoprotein Phosphatases; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Tumor Burden | 2018 |
Metabolic cofactors NAD(P)H and FAD as potential indicators of cancer cell response to chemotherapy with paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers; Flavin-Adenine Dinucleotide; Humans; Microscopy, Fluorescence, Multiphoton; NADP; Neoplasms; Oxidation-Reduction; Paclitaxel; Tumor Cells, Cultured | 2018 |
Directed Accumulation of Anticancer Depsipeptides by Characterization of Neoantimycins Biosynthetic Pathway and an NADPH-Dependent Reductase.
Topics: Antineoplastic Agents; Biosynthetic Pathways; Cell Line, Tumor; Depsipeptides; Genes, Bacterial; Humans; Multigene Family; NADP; Neoplasms; Organic Chemicals; Oxidoreductases; Peptide Synthases; Polyketide Synthases; Streptomyces | 2018 |
Lack of evidence for substrate channeling or flux between wildtype and mutant isocitrate dehydrogenase to produce the oncometabolite 2-hydroxyglutarate.
Topics: Cell Line, Tumor; HEK293 Cells; Humans; Hydroxybutyrates; Isocitrate Dehydrogenase; Models, Biological; Mutation; NADP; Neoplasm Proteins; Neoplasms; Protein Multimerization | 2018 |
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Topics: Cell Line; Cell Line, Tumor; Cytokines; Doxorubicin; Glucosephosphate Dehydrogenase; HEK293 Cells; Hep G2 Cells; Humans; Hydrogen Peroxide; MCF-7 Cells; NADP; Neoplasms; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Poly(ADP-ribose) Polymerases; Sirtuins; Up-Regulation | 2019 |
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP
Topics: Antineoplastic Agents; Azoles; Binding Sites; Cell Line, Tumor; Cell Proliferation; Escherichia coli; Glutamate Dehydrogenase; Humans; Isoindoles; Molecular Docking Simulation; NADP; Neoplasms; Organoselenium Compounds | 2019 |
Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; HEK293 Cells; Humans; Kinetics; Mice; Mice, Nude; Models, Molecular; NADP; Neoplasms; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Phosphorylation; Radiation, Ionizing; Reactive Oxygen Species; Ribosemonophosphates; Tyrosine; Up-Regulation | 2019 |
Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.
Topics: Cell Line, Tumor; Disease Management; fms-Like Tyrosine Kinase 3; Humans; Isocitrate Dehydrogenase; Janus Kinase 2; Models, Biological; Mutation; NADP; Neoplasms; Phosphorylation; Protein Binding; Protein Multimerization; Protein-Tyrosine Kinases | 2019 |
Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
Topics: Cell Line, Tumor; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Isoenzymes; Models, Biological; NADP; Neoplasms; Phosphatidylinositol 3-Kinases; Protein Subunits; Pyruvate Kinase; Reactive Oxygen Species; TOR Serine-Threonine Kinases | 2013 |
Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Carrier Proteins; Cell Line, Tumor; Embryonic Stem Cells; Energy Metabolism; Fatty Acids; Female; Folic Acid; Gene Expression Regulation, Neoplastic; Glycine; Humans; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Methotrexate; Mice; Multienzyme Complexes; NADP; Neoplasms; Protein Biosynthesis; Purines; Serine; Transferases | 2013 |
Altered antioxidant system stimulates dielectric barrier discharge plasma-induced cell death for solid tumor cell treatment.
Topics: Antioxidants; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Activation; Flow Cytometry; Glutathione; Glutathione Disulfide; HEK293 Cells; Humans; Membrane Potential, Mitochondrial; NADP; Neoplasms; Plasma Gases; Reactive Oxygen Species | 2014 |
Systemic anti-tumour effects of local thermally sensitive liposome therapy.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Combined Modality Therapy; Doxorubicin; Female; Flavin-Adenine Dinucleotide; Hemoglobins; Humans; Hyperthermia, Induced; Mice; NADP; Neoplasms; Oxygen; Polyethylene Glycols; Spectrum Analysis; Treatment Outcome; Tumor Burden | 2014 |
Quantitative measurement of redox potential in hypoxic cells using SERS nanosensors.
Topics: Biosensing Techniques; Cell Line, Tumor; Electrochemistry; Electrons; Gold; Green Fluorescent Proteins; Humans; Hypoxia; Metal Nanoparticles; Microscopy, Electron, Transmission; NAD; NADP; Nanoparticles; Nanotechnology; Neoplasms; Optics and Photonics; Oxidation-Reduction; Oxygen; Spectrum Analysis, Raman | 2014 |
Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Curcumin; Daunorubicin; Humans; NADP; Neoplasms | 2015 |
Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Diphosphonates; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Epigenesis, Genetic; Fatty Acids; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Ibandronic Acid; Lovastatin; Mevalonic Acid; MicroRNAs; NADP; Neoplasms; Protein Processing, Post-Translational; Simvastatin; Vitamin D | 2015 |
In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cetuximab; Cisplatin; Flavin-Adenine Dinucleotide; Humans; Microscopy, Fluorescence, Multiphoton; NADP; Neoplasms; Oxidation-Reduction; Single-Cell Analysis; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; NADP; Neoplasms; Pharmacogenetics; Precision Medicine | 2016 |
The metabolic interaction of cancer cells and fibroblasts - coupling between NAD(P)H and FAD, intracellular pH and hydrogen peroxide.
Topics: Cell Communication; Coculture Techniques; Fibroblasts; Flavin-Adenine Dinucleotide; Fluorescence; HeLa Cells; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intracellular Space; NADP; Neoplasms; Oxidation-Reduction | 2016 |
Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Topics: Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Citric Acid; Contact Inhibition; Cytosol; Extracellular Matrix; Glucose; Glutamic Acid; Glutamine; Homeostasis; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spheroids, Cellular | 2016 |
Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism.
Topics: Aminooxyacetic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Computer Simulation; Dichloroacetic Acid; Dihydroxyacetone Phosphate; Energy Metabolism; Enzyme Inhibitors; Female; Glycolysis; Humans; Kinetics; Mice; Mitochondria, Heart; Models, Molecular; NADP; Neoplasms; Oxamic Acid; Oxidative Phosphorylation; Rats, Wistar; Sus scrofa | 2017 |
Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-13C]Dehydroascorbic Acid Reduction Using 13C Magnetic Resonance Spectroscopy.
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Dehydroascorbic Acid; Humans; Isotope Labeling; Magnetic Resonance Spectroscopy; Mice; NADP; Neoplasms; Oxidative Stress | 2017 |
Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress.
Topics: Cell Survival; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glycolysis; Humans; NADP; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphofructokinase-1; Phosphofructokinase-1, Type C; RNA, Small Interfering; Snail Family Transcription Factors | 2017 |
The metabolic basis of vascular oxygen sensing: diversity, compartmentalization, and lessons from cancer.
Topics: Animals; Blood Vessels; Chemoreceptor Cells; Fluoroacetates; Glycolysis; Humans; Hypoxia; Mitochondria; Muscle, Smooth, Vascular; NADP; Neoplasms; Oxygen Consumption; Reactive Oxygen Species; Vascular Resistance | 2008 |
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation.
Topics: Cell Line; Cell Survival; Glucose; Glucosephosphate Dehydrogenase; Health; Humans; Hydrogen Peroxide; NADP; Neoplasms; Oxidation-Reduction; Superoxides | 2009 |
The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.
Topics: Antigens, Viral; Antioxidants; Catalytic Domain; Cell Transformation, Neoplastic; Disease Progression; DNA Damage; Epstein-Barr Virus Nuclear Antigens; Genomic Instability; Humans; Membrane Glycoproteins; Models, Biological; NADP; NADPH Oxidase 2; NADPH Oxidases; Neoplasms; Reactive Oxygen Species; Transcriptional Activation | 2009 |
Metabolic oxidative stress induced by a combination of 2-DG and 6-AN enhances radiation damage selectively in malignant cells via non-coordinated expression of antioxidant enzymes.
Topics: 6-Aminonicotinamide; Antioxidants; Catalase; Cell Line, Tumor; Deoxyglucose; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; NADP; Neoplasms; Oxidative Stress; Radiation Tolerance; Superoxide Dismutase | 2010 |
Suppression of mitochondrial NADP(+)-dependent isocitrate dehydrogenase activity enhances curcumin-induced apoptosis in HCT116 cells.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Curcumin; DNA Fragmentation; Drug Synergism; Escherichia coli; HCT116 Cells; HeLa Cells; Humans; Isocitrate Dehydrogenase; Mitochondria; Mutagenesis, Site-Directed; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Recombinant Proteins; RNA, Small Interfering; Transfection | 2011 |
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M).
Topics: Acetylcysteine; Antineoplastic Agents; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Microsomes, Liver; NADP; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sulfonamides | 2011 |
Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates.
Topics: Alcohol Dehydrogenase; Alkylation; Animals; Antibiotics, Antineoplastic; Biotransformation; Borohydrides; Cell Line, Tumor; Cell Survival; DNA; Enzyme Activation; Humans; NADP; Neoplasms; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2011 |
Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Topics: Acetyl Coenzyme A; Animals; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Citric Acid; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fumarate Hydratase; Glucose; Glutamine; Humans; Isocitrate Dehydrogenase; Kidney Neoplasms; Mice; Mitochondria; NADP; Neoplasms | 2011 |
Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation.
Topics: Acetyl Coenzyme A; Cell Hypoxia; Cell Line, Tumor; Humans; Isocitrate Dehydrogenase; Mitochondria; Mitochondrial Proteins; Mutation; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction | 2012 |
Cancer metabolism: Tumour friend or foe.
Topics: AMP-Activated Protein Kinases; Animals; Energy Metabolism; Female; Homeostasis; Male; NADP; Neoplasms; Oxidative Stress | 2012 |
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; CHO Cells; Contact Inhibition; Cricetinae; Energy Metabolism; Enzyme Activation; Female; Glucose; Homeostasis; Hydrogen Peroxide; Male; Mice; Mice, Nude; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species | 2012 |
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism.
Topics: Acetylglucosamine; Acylation; Adenosine Triphosphate; Animals; Cell Hypoxia; Cell Line; Cell Line, Tumor; Cell Proliferation; Glucose; Glycolysis; Glycosylation; Humans; Lactic Acid; Mice; Mice, Nude; N-Acetylglucosaminyltransferases; NADP; Neoplasms; Pentose Phosphate Pathway; Phosphofructokinase-1, Liver Type | 2012 |
Nitric oxide mediated photo-induced cell death in human malignant cells.
Topics: Apoptosis; Blotting, Western; Cell Death; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Fluorescein; Free Radicals; Humans; Immunohistochemistry; Indicators and Reagents; Light; Microscopy, Electron; NADP; Neoplasms; Nitric Oxide; Photochemotherapy; Time Factors | 2003 |
Levels of oxidized and reduced diphosphopyridine nucleotide and triphosphopyridine nucleotide in tumours.
Topics: Coenzymes; NAD; NADP; Neoplasms; Oxidation-Reduction | 1957 |
Mitochondria of the Ehrlich ascites-tumour cell. 2. Diphosphopyridine nucleotide- and triphosphopyridine nucleotide-dependent oxidation of isocitrate.
Topics: Ascites; Citrates; Coenzymes; Isocitrates; Mitochondria; NAD; NADP; Neoplasms; Oxidation-Reduction | 1961 |
Oxidation of reduced triphosphopyridine nucleotide by ascites tumor cells.
Topics: Ascites; Coenzymes; Diploidy; NADP; Neoplasms; Oxidation-Reduction | 1959 |
Hydrogen peroxide, catalase, glutathione peroxidase, quinones, nordihydroguaiaretic acid, and phosphopyridine nucleotides in relation to x-ray action on cancer cells.
Topics: Antineoplastic Agents; Carbohydrate Metabolism; Catalase; Glutathione Peroxidase; Hydrogen Peroxide; Masoprocol; Metabolism; NAD; NADP; Neoplasms; Neoplasms, Experimental; Nucleotides; Peroxidases; Quinones; X-Rays | 1963 |
AZO-DYE CARCINOGENESIS: RIBONUCLEOTIDES AND RIBONUCLEASES.
Topics: Adenosine Triphosphate; Azo Compounds; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Coloring Agents; DNA; DNA, Neoplasm; Glucosamine; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glucuronates; Guanine Nucleotides; Liver Neoplasms; Mice; NAD; NADP; Neoplasms; Nucleosides; Pathology; Pharmacology; Rats; Research; Ribonucleases; Ribonucleotides; RNA; Toxicology; Uracil Nucleotides | 1963 |
A DIRECT ASSAY FOR DIHYDROFOLATE REDUCTASE IN HUMAN LEUKOCYTES.
Topics: Animals; Chemistry Techniques, Analytical; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Methotrexate; Mice; Microchemistry; NADP; Neoplasms; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1964 |
CONCENTRATIONS AND RATES OF SYNTHESIS OF NICOTINAMIDE-ADENINE-DINUCLEODIDE PHOSPHATE IN PRECANCEROUS LIVERS AND HEPATOMAS INDUCED BY AZO-DYE FEEDING.
Topics: Adenine; Carcinogens; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; NADP; Neoplasms; Neoplasms, Experimental; Niacin; Niacinamide; p-Dimethylaminoazobenzene; Phosphates; Phosphotransferases; Rats; Research; Toxicology | 1964 |
LACTIC DEHYDROGENASE.
Topics: Cardiovascular Diseases; Clinical Enzyme Tests; Humans; L-Lactate Dehydrogenase; Metabolism; NAD; NADP; Neoplasms; Oxidoreductases | 1964 |
Induction of NAD(P)H:quinone reductase by probucol: a possible mechanism for protection against chemical carcinogenesis and toxicity.
Topics: Animals; Antioxidants; Enzyme Induction; Male; Mice; NAD(P)H Dehydrogenase (Quinone); NADP; Neoplasms; Probucol; Tissue Distribution | 2003 |
Anticancer drug testing in vitro: use of an activating system with the human tumor stem cell assay.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Line; Cyclophosphamide; Humans; In Vitro Techniques; Liver; NADP; Neoplasms; Pyrrolizidine Alkaloids; Rats | 1981 |
The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.
Topics: Amino Acid Sequence; Animals; Benzoquinones; Binding Sites; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Flavoproteins; Liver; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); NADP; Neoplasms; Oxidation-Reduction; Prodrugs; Rats; Triazines | 1995 |
Characterization of cytosolic malic enzyme in human tumor cells.
Topics: Adipose Tissue; Amino Acid Sequence; Base Sequence; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cytosol; Escherichia coli; Gene Expression; Gene Transfer Techniques; Humans; Isoenzymes; Kinetics; Liver; Malate Dehydrogenase; Molecular Sequence Data; NADP; Neoplasms; Peptide Fragments; Recombinant Proteins; Trypsin; Tumor Cells, Cultured | 1994 |
Niacin deficiency and cancer in women.
Topics: Diet; Female; Follow-Up Studies; Humans; Male; Middle Aged; NAD; NADP; Neoplasms; Niacin; Nutritional Status; Women's Health | 1993 |
A biomarker for the assessment of niacin nutriture as a potential preventive factor in carcinogenesis.
Topics: Adenosine Diphosphate Ribose; Biomarkers; Blood Cells; DNA Damage; DNA Repair; Humans; NAD; NADP; Neoplasms; Niacin; Nutritional Status; Polymers | 1993 |
An optimized semi-automatic rate method for serum glutathione reductase activity and its application to patients with malignant disease.
Topics: Aged; Buffers; Clinical Enzyme Tests; Edetic Acid; Enzyme Reactivators; Female; Glutathione Reductase; Humans; Male; Middle Aged; NADP; Neoplasm Metastasis; Neoplasms; Prognosis | 1976 |
Metabolic response to total parenteral nutrition in cancer patients.
Topics: Adult; Aged; Blood Glucose; Carbon Dioxide; Fatty Acids, Nonesterified; Female; Glucose; Humans; Insulin; Lactates; Male; Middle Aged; NADP; Neoplasms; Oxygen Consumption; Parenteral Nutrition; Parenteral Nutrition, Total | 1977 |
p-(Methylsulfinyl)phenyl nitrogen mustard as a novel bioreductive prodrug selective against hypoxic tumors.
Topics: Animals; Antineoplastic Agents; Cell Survival; CHO Cells; Cricetinae; Hypoxia; Liver; Mechlorethamine; Melanoma, Experimental; Mice; Mice, Inbred BALB C; NADP; Neoplasms; Oxidation-Reduction; Prodrugs; Sulfoxides; Tumor Cells, Cultured | 1992 |
Methylenetetrahydrofolate dehydrogenases in normal and transformed mammalian cells.
Topics: Aminohydrolases; Animals; Antibodies; Cell Line; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Antibody Technique; Formate-Tetrahydrofolate Ligase; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; NAD; NADP; Neoplasms; Oxidoreductases | 1988 |
Effects of riboflavin deficiency on metabolism of nitrosamines by rat liver microsomes.
Topics: Animals; Cytochrome P-450 CYP2E1; Eating; Male; Microsomes, Liver; Monoamine Oxidase; NADP; NADPH-Ferrihemoprotein Reductase; Neoplasms; Nitrosamines; Oxidoreductases, N-Demethylating; Oxygenases; Rats; Rats, Inbred Strains; Riboflavin Deficiency | 1985 |
Lack of dihydrofolate reductase in human tumor and leukemia cells in vivo.
Topics: Animals; Cattle; Cell Line; Cells, Cultured; Chickens; Humans; Leukemia, Experimental; Liver; Methotrexate; NADP; Neoplasms; Tetrahydrofolate Dehydrogenase; Tissue Distribution | 1985 |
On the occurence of the alpha isomer of diphosphopyridine nucleotide and on the dehydrogenases activated by it, in leucocytes and neoplastic tissues. A metabolic error.
Topics: Animals; Chromatography, Paper; Cyanides; Humans; L-Lactate Dehydrogenase; Leukocytes; Malate Dehydrogenase; Metabolism, Inborn Errors; NAD; NADP; Neoplasms; Neoplasms, Experimental; Oxidoreductases; Rats | 1968 |
Anomalies of growth and form in hydra: polarity, gradients, and a neoplasia analog.
Topics: Cnidaria; Congenital Abnormalities; Glucosephosphate Dehydrogenase; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Regeneration | 1969 |
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase | 1970 |
[Changes in intermediate metabolism in experimental chronic hypoxia].
Topics: Animals; Cyanides; Erythrocytes; Glucose; Glycolysis; Humans; Hypoxia; Lactates; Liver; Methylene Blue; NAD; NADP; Neoplasms; Oxygen Consumption; Pentosephosphates; Pyruvates; Rabbits; Rats | 1971 |
A comparative study on aflatoxin B 1 metabolism in mice and rats.
Topics: Absorption; Aflatoxins; Animals; Cell Fractionation; Chromatography, Paper; Chromatography, Thin Layer; Drug Resistance; Female; Fluorescence; Gastric Mucosa; Glucuronates; In Vitro Techniques; Liver; Male; Mice; Microsomes, Liver; NADP; Neoplasms; Rats; Species Specificity; Spectrophotometry; Sulfates; Ultraviolet Rays | 1971 |