nadp has been researched along with Leukemia L 1210 in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (87.88) | 18.7374 |
| 1990's | 4 (12.12) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MISRA, DK | 1 |
| Lehninger, AL; Moreadith, RW | 1 |
| Glisson, BS; Hande, KR; Ross, WE; Wozniak, AJ | 1 |
| Bertino, JR; Kamen, BA; Whyte-Bauer, W | 1 |
| Fan, CC; Huennekens, FM; Vitols, KS | 1 |
| Achari, A; Ballantine, SP; Bryant, PK; Champness, JN; Delves, CJ; Stammers, DK | 1 |
| Bertino, JR; Dicker, AP; Otter, GM; Schmid, FA; Schweitzer, BI; Sirotnak, FM; Volkenandt, M; Waltham, MC | 1 |
| Arimoto, T; Kohno, M; Takano, H; Yoshikawa, T | 1 |
| Huennekens, FM; Neef, VG | 2 |
| DiGirolamo, PM; Fujii, K; Huennekens, FM; Jacobsen, DW; Vitols, KS | 1 |
| Bertino, JR; Greenfield, NJ; Gupta, SV; Makulu, DR; Moroson, BA; Poe, M; Williams, MN | 1 |
| Bachur, NR; Gee, MV; Gordon, SL | 1 |
| Dauchy, RT; Sauer, LA | 1 |
| Davies, JF; Kaufman, BT; Kraut, J; McTigue, MA | 1 |
| Akman, SA; Block, JS; Chlebowski, RT; Dietrich, MF; Doroshow, JH | 1 |
| Akman, SA; Block, JB; Chlebowski, R; Dietrich, M; Limberg, P | 1 |
| Berger, NA; Berger, SJ; Sudar, DC | 1 |
| Baccanari, DP; Delcamp, TJ; Forsch, RA; Freisheim, JH; Rosowsky, A; Solan, VC | 1 |
| Beddell, CR; Champness, JN; Dann, JG; Eliopoulos, E; Geddes, AJ; North, AC; Ogg, D; Stammers, DK | 1 |
| Bachur, NR; Egorin, MJ; Fox, BM; Friedman, R; Gutierrez, PL | 1 |
| Huennekens, FM; Jackson, RC | 1 |
| Hansford, RG; Lehninger, AL | 1 |
| DiGirolamo, PM; Fujii, K; Henderson, GB; Huennekens, FM; Jacobsen, DW; Neef, VG; Rader, JI | 1 |
| Bertino, JR; Perkins, JP | 1 |
| Bertino, JR; Hillcoat, BL; Perkins, JP | 1 |
| Bertino, JR; Fischer, D; Hillman, G; Perkins, JP | 1 |
| Bertino, JR; Cashmore, AR; Hillcoat, BL | 1 |
| Kaufman, BT | 1 |
| Bertino, JR; McCullough, JL; Nixon, PF | 1 |
| Dunlap, RB; Freisheim, JH; Gundersen, LE; Harding, NG; Huennekens, FM; Levison, SA; Mell, GP | 1 |
| Gauldie, J; Hillcoat, BL | 1 |
| Bertino, JR; McCullough, JL | 1 |
3 review(s) available for nadp and Leukemia L 1210
| Article | Year |
|---|---|
B12 -- dependent methionine synthetase as a potential target for cancer chemotherapy.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Cells, Cultured; Cobamides; Enzyme Activation; Flavoproteins; Leukemia L1210; Methionine; Methyltransferases; Mice; NADP; Neoplasms; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1976 |
Folic acid and vitamin B12: transport and conversion to coenzyme forms.
Topics: Animals; Biological Transport, Active; Cell Line; Cell Membrane; Coenzymes; Folic Acid; Kinetics; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Models, Biological; Mutation; NADP; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Vitamin B 12 | 1974 |
Dihydrofolate reductases: structural and mechanistic aspects.
Topics: Animals; Bacteriophages; Carcinoma, Ehrlich Tumor; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chickens; Chromatography, Gel; Electrophoresis; Enterococcus faecalis; Kinetics; Lacticaseibacillus casei; Lactobacillus; Leukemia L1210; Leukocytes; Liver; Molecular Weight; NADP; Plasmodium; Spectrum Analysis; Streptococcus pneumoniae; Tetrahydrofolate Dehydrogenase; Thymus Gland; Ultraviolet Rays | 1971 |
30 other study(ies) available for nadp and Leukemia L 1210
| Article | Year |
|---|---|
A DIRECT ASSAY FOR DIHYDROFOLATE REDUCTASE IN HUMAN LEUKOCYTES.
Topics: Animals; Chemistry Techniques, Analytical; Folic Acid; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Methotrexate; Mice; Microchemistry; NADP; Neoplasms; Oxidoreductases; Research; Spectrophotometry; Tetrahydrofolate Dehydrogenase | 1964 |
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glutamic Acid; Glutamine; Kidney; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondria, Liver; NAD; NADP; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymoma; Thymus Neoplasms | 1984 |
Inhibition of etoposide-induced DNA damage and cytotoxicity in L1210 cells by dehydrogenase inhibitors and other agents.
Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Benzoates; Benzoic Acid; Cell Survival; Disulfiram; Ditiocarb; DNA; Etoposide; Leukemia L1210; Mice; NADP; Podophyllotoxin; Thiocarbamates | 1984 |
A mechanism of resistance to methotrexate. NADPH but not NADH stimulation of methotrexate binding to dihydrofolate reductase.
Topics: Animals; Drug Resistance; Kinetics; Leukemia L1210; Methotrexate; Mice; NAD; NADP; Protein Binding; Tetrahydrofolate Dehydrogenase | 1983 |
Inhibition of dihydrofolate reductase by methotrexate: a new look at an old problem.
Topics: Animals; Catalysis; Cells, Cultured; Cysteine; Folic Acid Antagonists; Histidine; Kinetics; Leukemia L1210; Methotrexate; Mice; NADP; Structure-Activity Relationship | 1980 |
The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
Topics: Amino Acid Sequence; Animals; Binding Sites; Escherichia coli; Folic Acid Antagonists; Humans; Leukemia L1210; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Molecular Structure; NADP; Pneumocystis; Protein Conformation; Protein Folding; Sequence Homology, Amino Acid; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1994 |
Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Chromatography, Affinity; DNA Primers; DNA, Neoplasm; Drug Resistance; Enzyme Stability; Escherichia coli; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Models, Molecular; Molecular Sequence Data; NADP; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Tetrahydrofolate Dehydrogenase; Time Factors | 1993 |
Generation of reactive oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust particle components in L1210 cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylation; Animals; Cytochrome c Group; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Enzyme-Linked Immunosorbent Assay; Hydroxyl Radical; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Reactive Oxygen Species; Superoxides; Tumor Cells, Cultured; Vehicle Emissions | 1999 |
Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.
Topics: Animals; Binding Sites; Cells, Cultured; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Leukemia L1210; Methotrexate; NADP; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1975 |
Interaction of 1,N6-ethenoadenine derivatives of triphosphopyridine and reduced triphosphopyridine nucleotides with dihydrofolate reductase from amethopterin-resistant L1210 cells.
Topics: Animals; Binding Sites; Drug Resistance; Kinetics; Leukemia L1210; Methotrexate; Mice; NADP; Oxidation-Reduction; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1976 |
Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.
Topics: Animals; Chromatography, Affinity; Circular Dichroism; Drug Resistance; Leukemia L1210; Methotrexate; Molecular Weight; NADP; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Tryptophan | 1977 |
A general mechanism for microsomal activation of quinone anticancer agents to free radicals.
Topics: Animals; Antibiotics, Antineoplastic; Binding Sites; Biotransformation; Electron Transport; Free Radicals; In Vitro Techniques; Leukemia L1210; Male; Mice; Microsomes; Models, Chemical; NADP; Neoplasms, Experimental; Oxygen Consumption; Quinones; Rats | 1978 |
Identification and properties of the nicotinamide adenine dinucleotide (phosphate)+-dependent malic enzyme in mouse ascites tumor mitochondria.
Topics: Animals; Binding, Competitive; Carcinoma, Krebs 2; Cell Line; Isoenzymes; Kinetics; Leukemia L1210; Malate Dehydrogenase; Male; Mice; Mitochondria; NAD; NADP; Neoplasms, Experimental; Pyruvates; Sarcoma 180 | 1978 |
Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.
Topics: Amino Acid Sequence; Animals; Biopterins; Chickens; Humans; Hydrogen Bonding; Leukemia L1210; Liver; Mice; Models, Molecular; Molecular Sequence Data; NADP; Protein Binding; Protein Conformation; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; X-Ray Diffraction | 1992 |
Synergistic cytotoxicity between menadione and dicumarol vs. murine leukemia L1210.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Calcium; Cell Division; Cysteine; Dicumarol; Drug Synergism; Glutathione; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Oxygen Consumption; Quinones; Vitamin K | 1987 |
Modulation of cytotoxicity of menadione sodium bisulfite versus leukemia L1210 by the acid-soluble thiol pool.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Glutathione; Kinetics; Leukemia L1210; Mice; NADP; Oxidation-Reduction; Superoxides; Vitamin K; Vitamin K 3 | 1985 |
Metabolic consequences of DNA damage: DNA damage induces alterations in glucose metabolism by activation of poly (ADP-ribose) polymerase.
Topics: Adenosine Triphosphate; Animals; Cell Line; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glucosephosphates; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; NADP; Poly(ADP-ribose) Polymerases | 1986 |
Methotrexate analogues. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N epsilon-(haloacetyl)-L-lysine and N delta-(haloacetyl)-L-ornithine analogues and an acivicin analogue of methotrexate.
Topics: Acetates; Animals; Candida albicans; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Isoxazoles; Leukemia L1210; Lysine; Methotrexate; Mice; NADP; Ornithine; Protein Conformation; Spectrophotometry | 1987 |
The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme.
Topics: Animals; Binding Sites; Humans; Leukemia L1210; Mice; Models, Molecular; NADP; Neoplasm Proteins; Protein Binding; Protein Conformation; Species Specificity; Tetrahydrofolate Dehydrogenase; Trimethoprim; X-Ray Diffraction | 1987 |
Cellular activation of diaziquone [2,5-diaziridinyl-3,6-bis (carboethoxyamino)-1,4-benzoquinone] to its free radical species.
Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Cell Line; Ethylmaleimide; Free Radicals; Humans; Kinetics; Leukemia; Leukemia L1210; Mice; NADP; Oxygen Consumption | 1985 |
Turnover of dihydrofolate reductase in rapidly dividing cells.
Topics: Animals; Carbon Isotopes; Cell Division; Cells; Chromatography, Affinity; Drug Resistance, Microbial; Half-Life; Isotope Labeling; Kinetics; Lacticaseibacillus casei; Leucine; Leukemia L1210; Methotrexate; Mice; NADP; Polysaccharides; Tetrahydrofolate Dehydrogenase; Time Factors | 1973 |
Active oxidative decarboxylation of malate by mitochondria isolated from L-1210 ascites tumor cells.
Topics: Aerobiosis; Animals; Ascites; Coenzymes; Decarboxylation; In Vitro Techniques; Kinetics; Leukemia L1210; Magnesium; Malate Dehydrogenase; Malates; Manganese; Mice; Mice, Inbred Strains; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Surface-Active Agents; Vibration | 1973 |
Dihydrofolate reductase from the L1210R murine lymphoma. Fluorometric measurements of the interaction of the enzyme with coenzymes, substrates, and inhibitors.
Topics: Animals; Chemical Phenomena; Chemistry; Enzymes; Fluorometry; Folic Acid; Leukemia L1210; Lymphoma; Methotrexate; Mice; NADP; Triamterene | 1966 |
Dihydrofolate reductase from the L1210 R murine lymphoma. Further studies on the binding of substrates and inhibitors to the enzyme.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Fluorometry; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Leukemia L1210; Methotrexate; Mice; NADP; Protein Binding; Pyrimidines; Tetrahydrofolate Dehydrogenase; Triamterene | 1967 |
Antibody to dihydrofolate reductase from a methotrexate-resistant subline of the L1210 lymphoma.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Binding Sites; Bone Marrow; Carcinoma, Ehrlich Tumor; Chickens; Complement Fixation Tests; Escherichia coli; Guinea Pigs; Humans; Immune Sera; Immunodiffusion; Leukemia L1210; Leukemia, Experimental; Liver; Lymphoma; Mice; NAD; NADP; Rabbits; Sarcoma 180; Species Specificity; Tetrahydrofolate Dehydrogenase | 1969 |
"Induction" of dihydrofolate reductase: purification and properties of the "induced" human erythrocyte and leukocyte enzyme and normal bone marrow enzyme.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromatography; Enzyme Activation; Enzyme Induction; Erythrocytes; Folic Acid; Humans; Hydrogen-Ion Concentration; Immune Sera; Leukemia L1210; Leukocytes; Methotrexate; Molecular Weight; NAD; NADP; Neoplasms; Protein Denaturation; Tetrahydrofolate Dehydrogenase | 1970 |
Isoelectric focusing studies on dihydrofolic reductase.
Topics: Animals; Cell Line; Chickens; Electrophoresis; Escherichia coli; Isoelectric Focusing; Leukemia L1210; Liver; NAD; NADP; Neoplasms, Experimental; Saccharomyces; Salmonella typhimurium; Tetrahydrofolate Dehydrogenase | 1971 |
Kinetic investigation of the reaction mechanism of dihydrofolate reductase from L1210 cells.
Topics: Animals; Binding Sites; Chromatography, Gel; Computers; Folic Acid Antagonists; Kinetics; Leukemia L1210; NADP; Protein Binding; Spectrum Analysis; Tetrahydrofolate Dehydrogenase; Triamterene; Ultraviolet Rays | 1971 |
Purification of tetrahydrofolate dehydrogenase by affinity chromatography.
Topics: Alkylation; Ammonium Sulfate; Animals; Buffers; Cell Line; Chemical Precipitation; Chromatography, Affinity; Chromatography, Gel; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Leukemia L1210; Methods; Methotrexate; NADP; Osmolar Concentration; Polysaccharides; Protein Binding; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays | 1972 |
Dihydrofolate reductase from mouse liver and spleen. Purification, properties and inhibition by substituted 2,4-diaminopyrimidines and 4,6-diaminotriazines.
Topics: Animals; Antigen-Antibody Reactions; Cell Line; Chromatography; Chromatography, Gel; Enzyme Activation; Folic Acid; Folic Acid Antagonists; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leukemia L1210; Liver; Lymphoma; Methotrexate; Mice; Mice, Inbred Strains; NADP; Potassium Chloride; Protein Denaturation; Pyrimidines; Spleen; Tetrahydrofolate Dehydrogenase; Triazines; Urea | 1971 |