nadp has been researched along with Disease Models, Animal in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (5.69) | 18.7374 |
| 1990's | 6 (4.88) | 18.2507 |
| 2000's | 31 (25.20) | 29.6817 |
| 2010's | 62 (50.41) | 24.3611 |
| 2020's | 17 (13.82) | 2.80 |
| Authors | Studies |
|---|---|
| Adjali, O; Audrain, C; Cronin, T; Croyal, M; Ducloyer, JB; Isiegas, C; Libeau, L; Mendes-Madeira, A; Morival, C; Pichard, V; Provost, N; Toublanc, E | 1 |
| Bedke, T; Diercks, BP; Gagliani, N; Guse, AH; Huber, S; Lory, N; Meier, C; Mittrücker, HW; Nawrocki, M; Stumme, F | 1 |
| Chen, W; Chen, Y; Liu, M; Lu, Y; Wei, L; Xu, S; Zhang, Y; Zhong, C | 1 |
| Behzadi, G; Davoudi, S; Hosseinmardi, N; Janahmadi, M; Khatibi, VA; Mirnajafi-Zadeh, J; Mohammadi, M; Nazari, M; Rahdar, M; Raoufy, MR; Rezaei, M | 1 |
| Abram, CL; Bevilacqua, D; Cassatella, MA; Caveggion, E; Cestari, T; Constantin, G; Costa, S; De Sanctis, F; Donini, M; Dusi, S; Gasperini, S; Girolomoni, G; Lonardi, S; Lowell, CA; Pettinella, F; Rodegher, P; Scapini, P; Tagliaro, F; Ugel, S; Vermi, W; Zenaro, E | 1 |
| Black, SM; Du, Q; Gu, C; Han, Y; Sun, H; Sun, S; Tang, H; Wang, H; Xu, Y; Zhang, F | 1 |
| Aires, R; Campagnaro, BP; Campos-Toimil, M; Leal, MAS; Marques, VB; Meyrelles, SS; Pandolfi, T; Pereira, TMC; Vasquez, EC | 1 |
| Cao, JF; Chai, XM; Chen, PM; Peng, P; Qian, K; Qin, ZH; Sheng, R; Wang, YF; Xie, H; Zhang, LW; Zhu, J | 1 |
| Chen, Y; Cho, GJ; Choi, HS; Chung, HT; Joe, Y; Kim, HJ; Kim, UH; Park, J; Park, JW; Rah, SY; Ryter, SW; Ryu, J | 1 |
| Chang, YK; Choi, DE; Choi, DH; Choi, H; Hwang, JH; Jeong, JY; Kim, JH; Lee, CH; Lee, KW; Moon, SJ; Na, KR | 1 |
| Clément, DA; Coelho, D; Dussurget, O; Gelin, M; Huteau, V; Labesse, G; Leseigneur, C; Lionne, C; Pochet, S | 1 |
| Du, X; Hall, MS; Helke, KL; Krupenko, NI; Krupenko, SA; Pediaditakis, P; Sharma, J; Sumner, S | 1 |
| Bermúdez-Muñoz, JM; Celaya, AM; Hijazo-Pechero, S; Serrano, M; Varela-Nieto, I; Wang, J | 1 |
| Bottino, C; Caretti, G; Filippakopoulos, P; Fittipaldi, R; Mamchaoui, K; Nevi, L; Segatto, M; Szokoll, R | 1 |
| Alan Maschek, J; Byun, J; Huang, CY; Ikeda, Y; Imai, N; Kashihara, T; Kashyap, S; Mizushima, W; Oka, SI; Ralda, G; Sadoshima, J; Tippetts, TS; Tong, M; Venkatesh, S; Warren, JS; Xu, X; Zhai, P | 1 |
| Chen, Z; Han, R; Li, M; Mao, GH; Qin, ZH; She, J; Sheng, R; Wang, F; Wang, XX; Wu, JC; Zhang, R | 1 |
| Chen, C; Chen, J; Huang, B; Liu, Y; Lv, J; Ma, J; Tang, K; Tang, L; Wang, D; Wei, K; Zeng, L; Zhang, H; Zhou, L; Zhou, Y; Zhu, L | 1 |
| Chen, F; Cheng, XY; Li, J; Liu, HT; Wang, R; Yang, D; Yang, H; Yang, XH; Yao, Y; Zheng, P | 1 |
| de Bari, L; De Filippis, B; Lacivita, E; Laviola, G; Leopoldo, M; Vacca, RA; Valenti, D; Vigli, D | 1 |
| Filipović, D; Todorović, N | 1 |
| Chung, J; Kang, KS; Kim, EY; Kim, H; Kim, MJ; Koh, H; Lee, Y; Min, B; Park, HT; Son, JH; Yang, J; Yoon, W | 1 |
| Alam, SR; Hu, S; Kashatus, D; Periasamy, A; Siller, KH; Svindrych, Z; Wallrabe, H; Wang, T | 1 |
| Anderson, RE; Brush, RS; Hurley, JB; Jankowski, CSR; Lindsay, KJ; Linton, JD; Rajala, A; Rajala, RVS; Tsantilas, K; Wang, Y | 1 |
| Hosoda, K; Imahori, T; Irino, Y; Kohmura, E; Kohta, M; Matsuo, K; Nagashima, H; Nakai, T; Sasayama, T; Sato, N; Shinohara, M; Tanaka, J; Tanaka, K; Yamamoto, Y | 1 |
| Boyd, K; Ding, D; Han, C; Hirst, J; Kim, MJ; Linser, P; Meneses, Z; Miyakawa, T; Park, HJ; Salvi, R; Santostefano, K; Slade, C; Someya, S; Tanokura, M; Terada, N; Walker, L; White, K | 1 |
| Han, SJ; Kim, JI; Kong, MJ; Park, JW; Park, KM | 1 |
| Gastaldello, S; Gorza, L; Lechado I Terradas, A; Namuduri, AV; Traini, L; Vitadello, M | 1 |
| Dudenkova, VV; Lukina, MM; Shimolina, LE; Shirmanova, MV; Snopova, LB; Zagaynova, EV | 1 |
| Cha, SS; Chung, KM; Jeong, BG; Kim, MK; Lee, TH; Na, JH; Park, SB | 1 |
| Brewer, GJ; Dong, Y | 1 |
| Choi, JG; Du, XF; Eo, H; Hong, SP; Huh, E; Jeong, JS; Kim Pak, Y; Kwon, Y; Oh, MS; Sim, Y; Soh, HY | 1 |
| Berlin, T; Bragin, D; Kraynik, J; Nemoto, EM; Pappu, S; Stippler, M; Yonas, H | 1 |
| Brewer, MD; Du, W; Jiang, P; Mak, TW; Mancuso, A; Minn, AJ; Stonestrom, A; Wu, M; Yang, X | 1 |
| Armstrong, JA; Booth, DM; Cane, MC; Cash, N; Chvanov, M; Criddle, DN; Dingsdale, H; Elliott, VL; Greenhalf, W; Huang, W; Jaffar, M; Javed, MA; Kaphalia, BS; Li, Y; Mukherjee, R; Petersen, OH; Sutton, R; Tepikin, AV | 1 |
| Bytautiene, E; Drever, N; Hill, AJ; Saade, G; Tamayo, E; Yin, H | 1 |
| Brewer, GJ; Ghosh, D | 1 |
| Bermingham, B; Darji, S; Geurts, AM; Guha, A; Jacob, HJ; Jin, C; Lambert, NA; O'Connor, PM; Ocasio, H; Patel, R; Smith, SM; Stilphen, CA; Sun, J | 1 |
| Asara, JM; Filiou, MD; Landgraf, R; Nussbaumer, M; Teplytska, L; Turck, CW | 1 |
| Cuzzocrea, S; Doyle, T; Esposito, E; Jacobson, KA; Janes, K; Salvemini, D; Tosh, DK | 1 |
| Ahn, S; Jeon, MJ; Kim, H; Kim, OH; Lee, C; Lee, Y; Oh, BC; Yu, U | 1 |
| Bennett, ES; Chapalamadugu, KC; Kolliputi, N; Panguluri, SK; Tipparaju, SM | 1 |
| Devalaraja-Narashimha, K; Kim, J; Padanilam, BJ | 1 |
| Mamaeva, GI; Mikhaĭlov, VM | 1 |
| Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I | 1 |
| Dolenec, P; Mršić-Pelčić, J; Pilipović, K; Župan, G; Župan, Ž | 1 |
| Gao, E; Huang, R; Li, D; Li, X; Li, Y; Ma, S; Pei, H; Peng, C; Song, X; Tan, Y; Wang, Q; Yang, D; Yang, Y | 1 |
| Bettaieb, A; Brandes, RP; Chao, TI; Chen, X; Haj, FG; Jiang, JX; Katsuyama, M; Kiss, Z; Sasaki, Y; Schröder, K; Shah, A; Szyndralewiez, C; Tian, J; Török, NJ; Xi, Y; Yabe-Nishimura, C | 1 |
| Biondaro Góis, M; de Almeida Araújo, EJ; de Araujo Pereira, LG; de Mello Gonçales Sant'Ana, D; Garcia, JL; Martins Moreira, N; Nogueira de Melo, Gde A; Vicentino-Vieira, SL | 1 |
| Cheng, H; Han, P; Hu, Y; Huang, Y; Jian, C; Lei, L; Lv, Q; Men, Y; Sun, T; Wang, X; Xiong, JW; Xu, J; Yang, R; Zhang, C; Zhang, M; Zhou, X; Zhu, X | 1 |
| Araki, T; Fukuda, Y; Ohshima, T; Sakuraba, H; Shibata, T; Sone, T; Yoneda, K | 1 |
| Baker, AA; Heck, DE; Jan, YH; Laskin, DL; Laskin, JD; Mishin, V; Richardson, JR | 1 |
| Chen, P; Dong, LH; Duan, ZL; Han, M; Li, H; Li, L; Lin, YL; Miao, SB; Shu, YN; Song, Y; Sun, SG; Yin, YJ; Zhao, LL | 1 |
| Davidson, SM; Duchen, MR; Foote, K; Ganesan, A; Gosain, R; Graeff, R; Kunuthur, S; Patel, S; Tan, N; Tyser, R; Yellon, DM; Zhao, YJ | 1 |
| Brewer, GJ; LeVault, KR; Tischkau, SA | 1 |
| Han, H; Lu, J; Sun, J; Xu, T; Yan, J; Zhang, Y; Zhou, C; Zhu, S | 1 |
| Agarkov, AA; Popova, TN; Voronkova, YG; Zinovkin, RA | 1 |
| Del Bufalo, D; Desideri, M; Favia, A; Filippini, A; Montesano, C; Nicoletti, C; Orlandi, A; Padula, F; Pafumi, I; Palombi, F; Passeri, D; Sergi, M; Ziparo, E | 1 |
| Di, S; Fan, C; Han, J; Hu, W; Jiang, S; Li, T; Li, X; Liu, Y; Ma, Z; Wu, G; Xin, Z; Yan, X; Yang, Y; Zhu, Y | 1 |
| Abusleme, L; Bryant, CE; Deming, C; Ding, L; Falcone, EL; Holland, SM; Hsu, AP; Kuhns, DB; Lionakis, MS; Moutsopoulos, NM; Quiñones, M; Segre, JA; Swamydas, M; Zelazny, AM | 1 |
| Bayerl, SH; Brandenburg, S; Cseresnyes, Z; Czabanka, MA; Niesner, R; Pohlan, J; Radbruch, H; Vajkoczy, P | 1 |
| Ji, MH; Li, HH; Li, KY; Sun, XR; Wu, J; Yang, JJ; Zhang, H; Zhao, HT | 1 |
| de Vries, HJ; Niessen, HW; Rodenburg, RJ; Stienen, GJ; Wintjes, LT; Wüst, RC | 1 |
| Akimoto, K; Inoue, K; Kubota, K; Shimizu, T; Tanaka, G | 1 |
| Dovgan', OV; Maisky, VA; Mankivska, OP; Maznychenko, AV; Schomburg, ED; Steffens, H; Vlasenko, OV | 1 |
| Ito, S; Nezu, M; Saigusa, D; Souma, T; Suzuki, N; Suzuki, T; Yamamoto, M; Yu, L | 1 |
| Deshpande, DA; Guedes, AGP; Kannan, MS; Lund, FE; Subramanian, S; Walseth, TF | 1 |
| Cao, L; Chen, J; Feng, X; Han, F; Li, M; Qin, YY; Qin, ZH; Shen, XK; Sheng, R; Sun, M; Wang, J | 1 |
| Bousquet, P; de Champlain, J; Jaffré, F; Laplante, MA; Maroteaux, L; Monassier, L | 1 |
| Catalano, D; Dolganiuc, A; Hritz, I; Kodys, K; Kurt-Jones, E; Mandrekar, P; Szabo, G; Velayudham, A | 1 |
| Bränström, R; Dey, D; Forsberg, L; Lu, M; Sjöholm, A; Zhang, F; Zhang, Q | 1 |
| Bauer, I; Heiser, J; Kubulus, D; Mathes, A; Pavlidis, D; Pradarutti, S; Rensing, H; Reus, E; Thierbach, JT; Wolf, B | 1 |
| Zimmerman, MC; Zucker, IH | 1 |
| Guan, Y; Montrose, MH; Pritts, TA; Worrell, RT | 1 |
| Kondeva-Burdina, MS; Krasteva, IN; Mitcheva, MK; Nikolov, SD; Simeonova, RL; Vitcheva, VB | 1 |
| Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I | 1 |
| Brummel, TJ; Chen, YC; Ciou, SC; Huang, MH; Li, H; Liang, CJ; Sang, TK; Wang, CT; Wang, CY; Wang, HD; Wang, YY; Yen, TL; Yuh, CH | 1 |
| Brittian, KR; Cai, L; Chen, Q; Li, X; McClain, CJ; Prabhu, SD; Tan, Y; Yin, X; Zhou, Z | 1 |
| Gebert, A; Gehlsen, U; Huettmann, G; Koop, N; Oetke, A; Paulsen, F; Steven, P; Szaszák, M | 1 |
| Jover, B; Lajoix, AD; Oudot, C; Rugale, C | 1 |
| Her, S; Joung, HY; Jung, EY; Kim, K; Lee, MS; Shim, I | 1 |
| Johnston, KC; Southerland, AM | 1 |
| Chen, GC; Duan, SB; Liu, GL; Pan, P; Wang, P; Xu, XQ | 1 |
| Briet, M; Ebrahimian, T; Gonzalez, FJ; Kasal, DA; Leibowitz, A; Marchesi, C; Neves, MF; Offermanns, S; Paradis, P; Rautureau, Y; Rehman, A; Schiffrin, EL; Simeone, SM | 1 |
| Jerkic, M; Letarte, M; Sotov, V | 1 |
| Faut, M; Mazzetti, MB; Paiz, A; San Martín de Viale, LC | 1 |
| Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP; Santos, MS; Seiça, R | 1 |
| Buchheim, K; Gabriel, S; Heinemann, U; Kann, O; Kovacs, R; Schuchmann, S | 1 |
| Kunes, J; Mazancova, K; Miksik, I; Pácha, J | 1 |
| Christen, S; Ghielmetti, M; Leib, SL; Ren, H; Täuber, MG | 1 |
| Begleiter, A; Bird, RP; Curphey, TJ; Sivananthan, K | 1 |
| Chrissobolis, S; Drummond, GR; Paravicini, TM; Sobey, CG | 1 |
| Cosi, C; Fluit, P; Gallo-Hendrikx, E; Marien, MR; Martel, JC; Mount, HT; Wu, Y | 1 |
| Amiri, F; Iglarz, M; Schiffrin, EL; Touyz, RM; Viel, EC | 1 |
| Billi de Catabbi, SC; Cochón, AC; Faletti, A; Fuentes, F; San Martín de Viale, LC | 1 |
| Akamatsu, H; Arai, H; Kojima, K; Shimoyama, T; Sunamori, M; Tabuchi, N; Tanaka, H | 1 |
| Godbole, MM; Gupta, SK; Pandey, CM; Pradhan, S; Rastogi, L; Rathore, P; Ray, M | 1 |
| Bellomo, M; Floyd, BC; Gupte, RS; Gupte, SA; Labinskyy, V; Levine, RJ; Lionetti, V; Ojaimi, C; Recchia, FA; Wolin, MS; Young, ME | 1 |
| Bianchi, ML; Catão, CS; Curti, C; Martins, NM; Santos, AC; Santos, NA | 1 |
| Bauer, I; Bentley, A; Kubulus, D; Mathes, AM; Pradarutti, S; Rensing, H; Weiler, J; Wolf, B; Ziegeler, S | 1 |
| Amorini, AM; Belli, A; Cimatti, M; Delfini, R; Di Pietro, V; Finocchiaro, A; Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R | 1 |
| de Diego-Otero, Y; Decara, J; Del Arco-Herrera, I; el Bekay, R; Rodríguez-de Fonseca, F; Romero-Zerbo, Y; Sanchez-Salido, L | 1 |
| Bauer, I; Bentley, A; Kubulus, D; Mathes, AM; Rensing, H; Waibel, L; Weiler, J; Wolf, B | 1 |
| Dunbar, GL; Haik, KL; Hargrove, C; Mazei-Robison, M; Patton, J; Sandstrom, MI; Shear, DA | 1 |
| Henderson, B | 1 |
| Gil'miiarova, FN; Radomskaia, VM; Vinogradova, LN | 1 |
| Conners, MS; Dunn, MW; Schwartzman, ML; Stoltz, RA; Urbano, F; Vafeas, C | 1 |
| Heinemann, U; Müller, W; Schuchmann, S | 1 |
| Eichhorn, M; Lütjen-Drecoll, E; May, CA; Neuhardt, T; Wilsch, C | 1 |
| Beck, H; Elger, CE; Goussakov, IV; Kunz, WS | 1 |
| Capdevila, JH; Falck, JR; Harris, RC | 1 |
| Hatakeyama, K; Kelly, KA; Marinos, RS; Martinez-Zaguilan, R; Meininger, CJ; Rojas, JD; Wu, G | 1 |
| Nakahata, E; Shindoh, C; Shindoh, Y; Takayama, T | 1 |
| Hathaway, CA; Heistad, DD; Miller, FJ; Piegors, DJ | 1 |
| Arruda, P; Castro, GM; de Nucci, G; Langone, F; Martins, ML; Muscará, MN; Papes, F; Rogério, F; Santos, LM; Teixeira, SA | 1 |
| August, M; Bodenschatz, M; Förstermann, U; Griendling, K; Kleschyov, AL; Lassègue, B; Li, H; Meinertz, T; Mollnau, H; Münzel, T; Oelze, M; Schulz, E; Szöcs, K; Tsilimingas, N; Walter, U; Wendt, M | 1 |
| Aykin-Burns, N; Ercal, N; Gurer-Orhan, H; McDonald, JD | 1 |
| Alvarez, A; Chávez, M; Chávez-Anaya, E; Medina, C; Medina, MD; Mendoza, R; Ramírez, MG; Sáenz, G; Vaca, G; Vargas, M | 1 |
| Ackerman, JJ; Chen, RD; Hotchkiss, RS; Karl, IE; Lowry, OH; Manchester, JK; Neil, JJ; Song, SK | 1 |
| Kirsch, WM; Schulz, DW | 1 |
| Engel, P; Marver, HS; Pimstone, NR; Schmid, R; Seitz, PT; Tenhunen, R | 1 |
| MacMillan, V | 1 |
| Ammon, HP; Steinke, J | 1 |
| Frenkel, R; Stafford, J; Stark, MJ | 1 |
5 review(s) available for nadp and Disease Models, Animal
| Article | Year |
|---|---|
CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets.
Topics: ADP-ribosyl Cyclase 1; Animals; Asthma; Calcium; Calcium Signaling; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Mice; MicroRNAs; Myocytes, Smooth Muscle; NAD; NADP; Respiratory Hypersensitivity | 2017 |
Considering hyperglycemia and thrombolysis in the Stroke Hyperglycemia Insulin Network Effort (SHINE) trial.
Topics: Animals; Brain Ischemia; Cerebral Hemorrhage; Diabetes Complications; Disease Models, Animal; Fibrinolytic Agents; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; NADP; NADPH Oxidases; Obesity; Recombinant Proteins; Single-Blind Method; Superoxides; Thrombolytic Therapy; Tissue Plasminogen Activator | 2012 |
Cell death and metabolic activity during epileptiform discharges and status epilepticus in the hippocampus.
Topics: Animals; Calcium Signaling; Cell Death; Disease Models, Animal; Hippocampus; NAD; NADP; Seizures; Status Epilepticus | 2002 |
The application of quantitative cytochemistry to the study of diseases of the connective tissues.
Topics: Animals; Arthritis, Rheumatoid; Cartilage, Articular; Cell Division; Connective Tissue Diseases; Disease Models, Animal; Epidermal Cells; Fractures, Bone; Glucosephosphate Dehydrogenase; Glycolysis; Hexosephosphates; Histocytochemistry; Humans; Lysosomes; Mitochondria; Mucopolysaccharidoses; NADP; Osteoarthritis; Pseudohypoparathyroidism; Psoriasis; Synovial Membrane; Vitamin K; Wound Healing; Zinc | 1983 |
Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase.
Topics: Animals; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Disease Models, Animal; Eicosanoids; Humans; Hypertension; Mixed Function Oxygenases; NADP; Oxygenases; Substrate Specificity | 2000 |
1 trial(s) available for nadp and Disease Models, Animal
| Article | Year |
|---|---|
Considering hyperglycemia and thrombolysis in the Stroke Hyperglycemia Insulin Network Effort (SHINE) trial.
Topics: Animals; Brain Ischemia; Cerebral Hemorrhage; Diabetes Complications; Disease Models, Animal; Fibrinolytic Agents; Humans; Hyperglycemia; Infusions, Intravenous; Insulin; NADP; NADPH Oxidases; Obesity; Recombinant Proteins; Single-Blind Method; Superoxides; Thrombolytic Therapy; Tissue Plasminogen Activator | 2012 |
118 other study(ies) available for nadp and Disease Models, Animal
| Article | Year |
|---|---|
Effect of retinol dehydrogenase gene transfer in a novel rat model of Stargardt disease.
Topics: Alcohol Oxidoreductases; Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Gene Knockdown Techniques; Gene Transfer Techniques; NADP; Photoreceptor Cells; Rats; Rats, Transgenic; Stargardt Disease; Vitamin A | 2021 |
Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide-Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice.
Topics: Animals; Calcium; Calcium Signaling; Carbolines; CD3 Complex; Cell Differentiation; Cell Plasticity; Cell Proliferation; Disease Models, Animal; Forkhead Transcription Factors; Inflammation; Interleukin-10; Intestines; Lymphocyte Activation; Mice, Inbred C57BL; Mice, Transgenic; NADP; Piperazines; Receptors, Antigen, T-Cell; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Up-Regulation | 2021 |
HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Histone Deacetylase 1; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidase 4; Oxidative Stress | 2022 |
The Glycolysis Inhibitor 2-Deoxy-D-Glucose Exerts Different Neuronal Effects at Circuit and Cellular Levels, Partially Reverses Behavioral Alterations and does not Prevent NADPH Diaphorase Activity Reduction in the Intrahippocampal Kainic Acid Model of Te
Topics: Animals; Deoxyglucose; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Glucose; Glycolysis; Hippocampus; Kainic Acid; NADP; NADPH Dehydrogenase; Neurons | 2023 |
Neutrophils inhibit γδ T cell functions in the imiquimod-induced mouse model of psoriasis.
Topics: Animals; Disease Models, Animal; Disease Progression; Eczema; Imiquimod; Mice; NADP; NADPH Oxidases; Neutrophils; Psoriasis | 2022 |
Salusin-β Promotes Vascular Calcification
Topics: Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Glucuronidase; Intercellular Signaling Peptides and Proteins; Klotho Proteins; Male; NADP; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Calcification | 2019 |
Sildenafil reduces aortic endothelial dysfunction and structural damage in spontaneously hypertensive rats: Role of NO, NADPH and COX-1 pathways.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cyclic GMP; Cyclooxygenase 1; Disease Models, Animal; Endothelial Progenitor Cells; Endothelium, Vascular; Hypertension; Lipid Peroxidation; Male; Membrane Proteins; NADP; Nitric Oxide; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Sildenafil Citrate; Vasodilation; Vasodilator Agents | 2020 |
Exogenous NADPH ameliorates myocardial ischemia-reperfusion injury in rats through activating AMPK/mTOR pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; Glucose; Injections, Intravenous; Male; Mitochondria; Myocardial Reperfusion Injury; NADP; Oxygen; Phosphorylation; Protective Agents; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases | 2020 |
Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Autophagosomes; Calcium; Carbon Monoxide; Cell Line; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; NADP; Ras Homolog Enriched in Brain Protein; RNA, Small Interfering; Sepsis; Sirtuin 1; TOR Serine-Threonine Kinases; Tristetraprolin | 2020 |
The potential roles of NAD(P)H:quinone oxidoreductase 1 in the development of diabetic nephropathy and actin polymerization.
Topics: Actins; Animals; Cells, Cultured; Diabetic Nephropathies; Disease Models, Animal; Humans; Kidney Glomerulus; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADP; Polymerization; Streptozocin | 2020 |
New Chemical Probe Targeting Bacterial NAD Kinase.
Topics: Adenine; Adenosine; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Bacterial Proteins; Disease Models, Animal; Enzyme Inhibitors; Mice; Models, Molecular; NADP; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Sepharose; Staphylococcus aureus | 2020 |
Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Female; Humans; Leucovorin; Lipid Metabolism; Male; Metabolomics; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NADP; Oxidoreductases Acting on CH-NH Group Donors; Sjogren-Larsson Syndrome; Tetrahydrofolates | 2020 |
G6PD overexpression protects from oxidative stress and age-related hearing loss.
Topics: Aging; Animals; Apoptosis; Auditory Threshold; Cochlea; Disease Models, Animal; Female; Glucosephosphate Dehydrogenase; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADP; Oxidative Stress; Presbycusis; Reactive Oxygen Species; Recombinant Proteins; Up-Regulation | 2020 |
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.
Topics: Animals; Azepines; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NADP; NADPH Oxidases; Neuromuscular Diseases; Nuclear Proteins; Oxidative Stress; Reactive Oxygen Species; Transcription Factors; Triazoles | 2020 |
Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cells, Cultured; Cytokines; Diabetic Cardiomyopathies; Diet, High-Fat; Disease Models, Animal; Fibrosis; Glutathione; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitophagy; Myocytes, Cardiac; NAD; NADP; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Rats, Wistar; Sirtuins; Thioredoxins | 2021 |
NADPH is superior to NADH or edaravone in ameliorating metabolic disturbance and brain injury in ischemic stroke.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Mice; Mice, Inbred ICR; NAD; NADP; Neuroprotective Agents; Random Allocation; Reperfusion Injury; Stress, Physiological | 2022 |
Hypoxia Promotes Breast Cancer Cell Growth by Activating a Glycogen Metabolic Program.
Topics: Animals; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glycogen; Humans; Hypoxia; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Metabolic Networks and Pathways; Mice; NADP; Phosphoenolpyruvate Carboxykinase (GTP); Reactive Oxygen Species | 2021 |
Astragaloside IV Ameliorates Cognitive Impairment and Neuroinflammation in an Oligomeric Aβ Induced Alzheimer's Disease Mouse Model via Inhibition of Microglial Activation and NADPH Oxidase Expression.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astragalus Plant; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Male; Maze Learning; Mice, Inbred ICR; Microglia; NADP; NADPH Oxidases; Neuroinflammatory Diseases; Neurons; Neuroprotective Agents; Phytotherapy; Reactive Oxygen Species; Saponins; Triterpenes | 2021 |
Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome.
Topics: Adenosine Triphosphate; Animals; Brain; Disease Models, Animal; Female; Glucosephosphate Dehydrogenase; Glutamic Acid; Histocompatibility Antigens; Horseradish Peroxidase; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Diseases; NADP; Piperazines; Reactive Oxygen Species; Receptors, Serotonin; Rett Syndrome; Serotonin Receptor Agonists; Superoxide Dismutase | 2017 |
Prefrontal cortical glutathione-dependent defense and proinflammatory mediators in chronically isolated rats: Modulation by fluoxetine or clozapine.
Topics: Animals; Antidepressive Agents; Clozapine; Cytokines; Defense Mechanisms; Disease Models, Animal; Fluoxetine; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Male; Mood Disorders; NADP; NF-kappa B; Nitric Oxide Synthase Type II; Prefrontal Cortex; Rats; Rats, Wistar; Social Isolation | 2017 |
Isocitrate protects DJ-1 null dopaminergic cells from oxidative stress through NADP+-dependent isocitrate dehydrogenase (IDH).
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Nerve Degeneration; Nerve Tissue Proteins; NF-E2 Transcription Factor; Oxidative Stress; Parkinson Disease | 2017 |
Segmented cell analyses to measure redox states of autofluorescent NAD(P)H, FAD & Trp in cancer cells by FLIM.
Topics: Animals; Cytosol; Disease Models, Animal; Doxorubicin; Flavin-Adenine Dinucleotide; Glucose; Heterografts; Humans; Microscopy, Fluorescence; Mitochondria; Molecular Imaging; NAD; NADP; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation | 2018 |
Pyruvate kinase M2 regulates photoreceptor structure, function, and viability.
Topics: Animals; Apoptosis; Carbon Isotopes; Cell Membrane; Cyclic Nucleotide Phosphodiesterases, Type 6; Disease Models, Animal; Electroretinography; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Integrases; Mice; Mice, Knockout; NADP; Phospholipids; Promoter Regions, Genetic; Protein Binding; Protein Isoforms; Pyruvate Kinase; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Signal Transduction; Staining and Labeling; Tomography, Optical Coherence; Transcription, Genetic; Triglycerides | 2018 |
Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion.
Topics: Animals; Antioxidants; Brain Infarction; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Glucosephosphate Dehydrogenase; HSP27 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Morpholines; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Protein Carbonylation; Pyrones; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger | 2018 |
Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.
Topics: Aging; Animals; Apoptosis; Cell Survival; Cochlea; Disease Models, Animal; Glutathione Reductase; Hair Cells, Auditory; Hearing Loss; Humans; Isocitrate Dehydrogenase; Male; Mice; Mitochondria; NADP; Neurons; Oxidative Stress; Oxygen Consumption; Spiral Ganglion; Thioredoxin Reductase 2 | 2018 |
Mitochondrial NADP
Topics: Animals; Antioxidants; Apoptosis; Cisplatin; Disease Models, Animal; Female; Glutathione; Isocitrate Dehydrogenase; Kidney Diseases; Kidney Tubules; Mice, Knockout; Mitochondria; NADP; Organophosphorus Compounds; Oxidative Stress; Piperidines; Signal Transduction | 2018 |
Sarcolemmal loss of active nNOS (Nos1) is an oxidative stress-dependent, early event driving disuse atrophy.
Topics: Animals; Bed Rest; Disease Models, Animal; Down-Regulation; Female; Forkhead Box Protein O3; Healthy Volunteers; Hindlimb Suspension; Humans; Male; Muscular Atrophy; NADP; Nitric Oxide Synthase Type I; Oxidative Stress; Protein Transport; Quadriceps Muscle; Rats, Wistar; Sarcolemma; Superoxides; Time Factors | 2018 |
In vivo metabolic and SHG imaging for monitoring of tumor response to chemotherapy.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Collagen; Colorectal Neoplasms; Disease Models, Animal; Female; Irinotecan; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; NADP; Paclitaxel; Second Harmonic Generation Microscopy | 2019 |
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Hydrolysis; Indicators and Reagents; Mice; Microbial Sensitivity Tests; NADP; Survival Analysis; Treatment Outcome | 2018 |
Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites.
Topics: Aging; Alzheimer Disease; Animals; Brain; Caenorhabditis elegans Proteins; Carrier Proteins; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Female; Hippocampus; Male; Metabolome; Mice; Mice, Transgenic; NAD; NADP; Oxidation-Reduction | 2019 |
Protective effects of DA-9805 on dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity in the models of Parkinson's disease.
Topics: Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Mice; Mice, Inbred ICR; NADP; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidopamine; Parkinson Disease; PC12 Cells; Plant Extracts; Plant Preparations; Rats | 2019 |
Microvascular shunts in the pathogenesis of high intracranial pressure.
Topics: Animals; Blood Flow Velocity; Cerebrovascular Circulation; Disease Models, Animal; Erythrocyte Count; Functional Laterality; Intracranial Hypertension; Intracranial Pressure; Laser-Doppler Flowmetry; Male; Microcirculation; NADP; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
TAp73 enhances the pentose phosphate pathway and supports cell proliferation.
Topics: Animals; Antioxidants; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Disease Models, Animal; DNA; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucosephosphate Dehydrogenase; Humans; Mice; NADP; Nuclear Proteins; Pentose Phosphate Pathway; Reactive Oxygen Species | 2013 |
Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis.
Topics: Acinar Cells; Acyltransferases; Animals; Apoptosis; Calcium; Calcium Signaling; Carboxylesterase; Cells, Cultured; Disease Models, Animal; Ethanol; Fatty Acids; Fatty Acids, Monounsaturated; Fomepizole; Membrane Potential, Mitochondrial; Mice; Mitochondria; NADP; Necrosis; Pancreatitis, Alcoholic; Pyrazoles; Pyrones | 2014 |
The role of NADPH oxidase in a mouse model of fetal alcohol syndrome.
Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Alcohol Spectrum Disorders; Fetus; Mice, Inbred C57BL; NADP; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2014 |
External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons.
Topics: Aging; Alzheimer Disease; Animals; Cell Death; Cells, Cultured; Cysteine; Cystine; Disease Models, Animal; Extracellular Space; Glutathione; Male; Mice; Mice, Transgenic; NADP; Neurons; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species | 2014 |
HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats.
Topics: Animals; Disease Models, Animal; Hydrogen; Hydrogen-Ion Concentration; Hypertension; Ion Channels; Kidney Diseases; Loop of Henle; Male; NADP; Patch-Clamp Techniques; Rats; Rats, Inbred Dahl; Rats, Mutant Strains; Reactive Oxygen Species; Sodium; Superoxides | 2014 |
Behavioral extremes of trait anxiety in mice are characterized by distinct metabolic profiles.
Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Computer Simulation; Disease Models, Animal; Gyrus Cinguli; Male; Mass Spectrometry; Metabolic Networks and Pathways; Mice; NADP; Oxidative Stress; Predictive Value of Tests; Proteomics; Pyruvic Acid; Tandem Mass Spectrometry | 2014 |
A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Hyperalgesia; Male; NADP; Neuralgia; Neuroglia; NF-kappa B; Oxidation-Reduction; Paclitaxel; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha | 2014 |
High resolution in vivo 31P-MRS of the liver: potential advantages in the assessment of non-alcoholic fatty liver disease.
Topics: Animals; Disease Models, Animal; Ethanolamines; Glycerylphosphorylcholine; Liver Cirrhosis; Magnetic Resonance Spectroscopy; Male; NADP; Non-alcoholic Fatty Liver Disease; Phosphatidylethanolamines; Phosphorus; Phosphorylcholine; Rats; Rats, Sprague-Dawley | 2015 |
High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulation.
Topics: Action Potentials; Animals; Biomarkers; Bradycardia; Cell Line; Disease Models, Animal; Electrocardiography; Heart Conduction System; Heart Rate; Histone Deacetylase Inhibitors; Hyperoxia; Kv1.5 Potassium Channel; L-Lactate Dehydrogenase; Mice; Myocytes, Cardiac; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Rats; Signal Transduction; Sirtuin 1; Time Factors; Troponin I | 2015 |
TIGAR regulates glycolysis in ischemic kidney proximal tubules.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Cells, Cultured; Disease Models, Animal; Glucosephosphate Dehydrogenase; Glutathione; Glycolysis; Injections, Intravenous; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Mice, Knockout; NADP; Oxidative Stress; Phosphofructokinase-1; Phosphoric Monoester Hydrolases; Proteins; Reperfusion Injury; RNA Interference; RNA, Small Interfering; Severity of Illness Index; Time Factors; Tumor Suppressor Protein p53 | 2015 |
[The effect of NADP+ on electrophysiological properties of cardiomyocytes of C57BL/6 and mdx mice].
Topics: Action Potentials; Animals; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Heart Rate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; NADP; Oxidative Stress | 2013 |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid | 2014 |
A single dose of PPARγ agonist pioglitazone reduces cortical oxidative damage and microglial reaction following lateral fluid percussion brain injury in rats.
Topics: Animals; Brain Edema; Brain Injuries; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Lipid Peroxidation; Male; Microglia; NADP; Neuroprotective Agents; Oxidative Stress; Percussion; Pioglitazone; Rats; Rats, Wistar; Thiazolidinediones | 2015 |
TNF-α inhibitor protects against myocardial ischemia/reperfusion injury via Notch1-mediated suppression of oxidative/nitrative stress.
Topics: Animals; Calcium-Binding Proteins; Disease Models, Animal; Down-Regulation; Enzyme Activation; Etanercept; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NADP; Nitric Oxide Synthase Type II; Onium Compounds; Organometallic Compounds; Oxidative Stress; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Receptor, Notch1; RNA Interference; RNA, Small Interfering; Salicylates; Serrate-Jagged Proteins; Tumor Necrosis Factor-alpha | 2015 |
Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
Topics: Animals; Biomarkers; Biopsy; Diet; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Insulin Resistance; Lipid Peroxidation; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; NADP; NADPH Oxidase 4; NADPH Oxidases; Obesity; Oxidative Stress; Protein Phosphatase 1; Pyrazoles; Pyrazolones; Pyridines; Pyridones; Stress, Physiological | 2015 |
Oral dependent-dose toxoplasmic infection model induced by oocysts in rats: Myenteric plexus and jejunal wall changes.
Topics: Animals; Antibodies, Protozoan; Disease Models, Animal; Histocytochemistry; Immunoglobulin G; Jejunum; Male; Myenteric Plexus; NAD; NADP; Neurons; Random Allocation; Rats; Rats, Wistar; Toxoplasma; Toxoplasmosis, Animal | 2015 |
Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish.
Topics: Actins; Animals; Animals, Genetically Modified; Bacterial Proteins; Disease Models, Animal; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Genes, Reporter; Luminescent Proteins; Membrane Proteins; Mitochondria; Mitochondrial Dynamics; Morpholinos; Muscle Development; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophies; NADP; Recombinant Fusion Proteins; Signal Transduction; Superoxide Dismutase; Time-Lapse Imaging; Zebrafish; Zebrafish Proteins | 2015 |
A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Amino Acid Sequence; Amino Acid Substitution; Animals; Biocatalysis; Catalytic Domain; Chickens; Databases, Protein; Disease Models, Animal; Fatty Liver; Gene Expression Regulation, Enzymologic; Hypothyroidism; Liver; Molecular Sequence Data; Mutant Proteins; NADP; Phenanthrenes; Protein Conformation; Protein Stability; Protein Subunits; Recombinant Proteins; Tyrosine | 2015 |
Vitamin K3 (menadione) redox cycling inhibits cytochrome P450-mediated metabolism and inhibits parathion intoxication.
Topics: Acetylcholinesterase; Activation, Metabolic; Animals; Cholinesterase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Female; GPI-Linked Proteins; Humans; Insecticides; Liver; Microsomes, Liver; NADP; Organophosphate Poisoning; Oxidation-Reduction; Paraoxon; Parathion; Rats, Long-Evans; Recombinant Proteins; Time Factors; Vitamin K 3 | 2015 |
TRAF6-Mediated SM22α K21 Ubiquitination Promotes G6PD Activation and NADPH Production, Contributing to GSH Homeostasis and VSMC Survival In Vitro and In Vivo.
Topics: Animals; Apoptosis; Becaplermin; Carotid Artery Injuries; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Glucosephosphate Dehydrogenase; Glutathione; Homeostasis; Male; Mice, Knockout; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADP; Neointima; Pentose Phosphate Pathway; Plaque, Atherosclerotic; Protein Transport; Proto-Oncogene Proteins c-sis; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Time Factors; TNF Receptor-Associated Factor 6; Transfection; Ubiquitination | 2015 |
Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.
Topics: Animals; Calcium Channels; Calcium Signaling; Carbolines; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NADP; Piperazines; Rats, Sprague-Dawley; Time Factors | 2015 |
Circadian Disruption Reveals a Correlation of an Oxidative GSH/GSSG Redox Shift with Learning and Impaired Memory in an Alzheimer's Disease Mouse Model.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Chronobiology Disorders; Disease Models, Animal; Gene Expression Regulation; Glutathione; Glutathione Disulfide; Humans; Memory Disorders; Mice; Mice, Transgenic; Mutation; NADP; Nitric Oxide Synthase Type II; Oxidation-Reduction | 2016 |
The role of rhynchophylline in alleviating early brain injury following subarachnoid hemorrhage in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; Hippocampus; Indole Alkaloids; Male; NAD(P)H Dehydrogenase (Quinone); NADP; NF-E2-Related Factor 2; Oxindoles; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Subarachnoid Hemorrhage; Tumor Necrosis Factor-alpha | 2016 |
Effect of SkQ1 on Activity of the Glutathione System and NADPH-Generating Enzymes in an Experimental Model of Hyperglycemia.
Topics: Animals; Antioxidants; Disease Models, Animal; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hyperglycemia; Isocitrate Dehydrogenase; Liver; Male; Mitochondria; NADP; Oxidation-Reduction; Plastoquinone; Rats; Reactive Oxygen Species | 2015 |
NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis.
Topics: Animals; Calcium Signaling; Carbolines; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Disease Progression; Gene Expression; Male; Melanoma; Melanoma, Experimental; Mice; NADP; Neoplasm Metastasis; Neovascularization, Pathologic; Piperazines; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
Icariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 9; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Drugs, Chinese Herbal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Esophageal Neoplasms; Eukaryotic Initiation Factor-2; Flavonoids; Glutathione; Humans; Male; Mice; NADP; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.
Topics: Adult; Animals; Citrobacter rodentium; Colitis; Crosses, Genetic; Dextran Sulfate; Disease Models, Animal; Disease Susceptibility; Female; Gene Expression; Granulomatous Disease, Chronic; Humans; Inflammatory Bowel Diseases; Mice; Mice, Knockout; Microbiota; NADP; NADPH Oxidases; Reactive Oxygen Species | 2016 |
Time lapse in vivo microscopy reveals distinct dynamics of microglia-tumor environment interactions-a new role for the tumor perivascular space as highway for trafficking microglia.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Movement; CX3C Chemokine Receptor 1; Disease Models, Animal; Gene-Environment Interaction; Glioma; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Intravital Microscopy; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Microscopy, Confocal; NADP; Neovascularization, Pathologic; Xenograft Model Antitumor Assays | 2016 |
Amelioration of oxidative stress-induced phenotype loss of parvalbumin interneurons might contribute to the beneficial effects of environmental enrichment in a rat model of post-traumatic stress disorder.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anxiety; Conditioning, Classical; Deoxyguanosine; Disease Models, Animal; Electroshock; Environment; Fear; GABAergic Neurons; Glutamate Decarboxylase; Hippocampus; Interneurons; Male; Maze Learning; NADP; NADPH Oxidase 2; NADPH Oxidase 4; Oxidative Stress; Parvalbumins; Phenotype; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spatial Memory; Stress Disorders, Post-Traumatic | 2016 |
Mitochondrial complex I dysfunction and altered NAD(P)H kinetics in rat myocardium in cardiac right ventricular hypertrophy and failure.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Heart; Hypertrophy, Right Ventricular; Male; Mitochondria; Myocardium; NAD; NADP; Oxygen Consumption; Rats, Wistar | 2016 |
Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Disease Models, Animal; DNA Breaks, Double-Stranded; Drug Synergism; Fibroblasts; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Mice; NADP; Neoplastic Stem Cells; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Thioredoxin-Disulfide Reductase; Thioredoxins; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2016 |
NADPH-diaphorase reactivity and Fos-immunoreactivity within the ventral horn of the lumbar spinal cord of cats submitted to acute muscle inflammation induced by injection of carrageenan.
Topics: Animals; Carrageenan; Cats; Disease Models, Animal; Inflammation; Male; NADP; NADPH Dehydrogenase; Neurons; Nitric Oxide Synthase; Pain; Proto-Oncogene Proteins c-fos; Spinal Cord | 2016 |
Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression.
Topics: Animals; Antioxidants; Cell Line; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Enzymologic; Genotype; Glucosephosphate Dehydrogenase; Glutathione; Humans; Kelch-Like ECH-Associated Protein 1; Kidney Tubular Necrosis, Acute; Kidney Tubules; Mice, Knockout; NADP; NF-E2-Related Factor 2; Oxidative Stress; Phenotype; Reactive Oxygen Species; Reperfusion Injury; RNA Interference; Signal Transduction; Time Factors; Transfection | 2017 |
Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, Animal; Humans; Inflammation; Mice; NADP; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; Reperfusion Injury; Stroke | 2017 |
Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Echocardiography, Doppler; Indoles; Isoproterenol; Mice; Mice, Inbred Strains; NADP; Probability; Quinolines; Random Allocation; Reactive Oxygen Species; Receptor, Serotonin, 5-HT2B; Reference Values; Sensitivity and Specificity; Serotonin Antagonists; Superoxides | 2008 |
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
Topics: Animals; Cytochrome P-450 CYP2E1; Disease Models, Animal; Ethanol; Fatty Liver; Hepatocytes; Interleukin-6; Lipopolysaccharide Receptors; Liver; Liver Diseases, Alcoholic; Lymphocyte Antigen 96; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; NADP; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2008 |
BLX-1002, a novel thiazolidinedione with no PPAR affinity, stimulates AMP-activated protein kinase activity, raises cytosolic Ca2+, and enhances glucose-stimulated insulin secretion in a PI3K-dependent manner.
Topics: AMP-Activated Protein Kinases; Animals; Calcium; Cells, Cultured; Cytosol; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Fenofibrate; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; KATP Channels; Mice; Mice, Inbred Strains; NADP; Obesity; Peroxisome Proliferator-Activated Receptors; Phosphatidylinositol 3-Kinases; Pioglitazone; Protein Kinase Inhibitors; Signal Transduction; Thiazolidinediones; Time Factors; Tissue Culture Techniques; Up-Regulation | 2009 |
Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock.
Topics: Animals; Blood Substitutes; Cytokines; Disease Models, Animal; Endothelin-1; Hemoglobins; Humans; Isotonic Solutions; Liver; Male; NADP; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ringer's Solution; Shock, Hemorrhagic; Time Factors | 2009 |
Mitochondrial dysfunction and mitochondrial-produced reactive oxygen species: new targets for neurogenic hypertension?
Topics: Animals; Cardiovascular System; Central Nervous System; Disease Models, Animal; Electron Transport; Hypertension; Medulla Oblongata; Mitochondria; NADP; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Superoxide Dismutase | 2009 |
Intestinal ischemia-reperfusion injury: reversible and irreversible damage imaged in vivo.
Topics: Animals; Biomarkers; Cell Shape; Disease Models, Animal; Hydrogen-Ion Concentration; Intestinal Mucosa; Jejunum; Male; Mice; Mice, Inbred ICR; Microcirculation; Microscopy, Confocal; Microscopy, Fluorescence; NADP; Permeability; Recovery of Function; Regional Blood Flow; Reperfusion Injury; Splanchnic Circulation; Time Factors | 2009 |
Effect of purified saponin mixture from Astragalus corniculatus on enzyme- and non-enzyme-induced lipid peroxidation in liver microsomes from spontaneously hypertensive rats and normotensive rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Astragalus Plant; Carbon Tetrachloride; Disease Models, Animal; Iron Compounds; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; NADP; Oxidative Stress; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Wistar; Saponins; Spectrophotometry | 2010 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila.
Topics: Aging; Aldose-Ketose Isomerases; Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Gene Knockdown Techniques; Humans; Huntington Disease; Longevity; Male; NADP; Neurons; Oxidative Stress; Pentose Phosphate Pathway; Peptides; Reactive Oxygen Species; RNA, Small Interfering | 2012 |
Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner.
Topics: Angiotensin II; Animals; Cardiomyopathy, Alcoholic; Cell Death; Disease Models, Animal; Disease Progression; Ethanol; Heart Ventricles; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NADP; Oxidative Stress; Protein Kinase C; Ventricular Remodeling | 2012 |
Two-photon fluorescence lifetime imaging monitors metabolic changes during wound healing of corneal epithelial cells in vitro.
Topics: Animals; Burns, Chemical; Cells, Cultured; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Female; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; NADP; Organ Culture Techniques; Sodium Hydroxide; Tomography, Optical Coherence; Wound Healing | 2012 |
[Oxydative stress and beneficial effect of sodium restriction on kidney damage associated with insulin resistance in rats].
Topics: Albuminuria; Animals; Blood Glucose; Diet, Sodium-Restricted; Disease Models, Animal; Fibrosis; Fructose; Insulin Resistance; Kidney Diseases; Male; NADP; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2012 |
The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Brain; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Indazoles; Male; Maze Learning; NADP; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Reaction Time; Restraint, Physical | 2012 |
Aged rats are susceptible to nephrotoxicity induced by iodinated contrast media.
Topics: Aging; Angiotensin II; Animals; Contrast Media; Diatrizoate Meglumine; Disease Models, Animal; Kidney; Kidney Diseases; Male; Malondialdehyde; NADP; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NADP; Oxidative Stress; PPAR gamma; Superoxide Dismutase; Vascular Diseases | 2013 |
Oxidative stress contributes to endothelial dysfunction in mouse models of hereditary hemorrhagic telangiectasia.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Animals; Disease Models, Animal; Endoglin; Endothelium, Vascular; Heterozygote; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondria; Models, Biological; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Telangiectasia, Hereditary Hemorrhagic | 2012 |
Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Topics: Allylisopropylacetamide; Animals; Disease Models, Animal; Glucose; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Heme; Liver; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Porphyria, Acute Intermittent; Pyridines; Rats; Reactive Oxygen Species | 2013 |
Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Adenine Nucleotides; Animals; Calcium; Cholestasis, Intrahepatic; Citrate (si)-Synthase; Disease Models, Animal; Energy Metabolism; Female; Hepatocytes; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; NADP; Oxygen Consumption; Random Allocation; Rats; Rats, Wistar | 2002 |
Placental 11beta-hydroxysteroid dehydrogenase in Dahl and spontaneously hypertensive rats.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Actins; Animals; Blood Pressure; Corticosterone; Disease Models, Animal; Female; Hydroxysteroid Dehydrogenases; Hypertension; Isoenzymes; Models, Cardiovascular; NADP; Organ Size; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Cerebral Cortex; Disease Models, Animal; Energy Metabolism; Free Radicals; Meningitis, Bacterial; NAD; NADP; Oxidative Stress; Pentose Phosphate Pathway; Rats; Rats, Wistar; Streptococcal Infections; Streptococcus pneumoniae | 2003 |
Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Colon; Colonic Neoplasms; Dimethyl Fumarate; Disease Models, Animal; Enzyme Induction; Fumarates; Glucuronosyltransferase; Glutathione Transferase; Inactivation, Metabolic; Intestinal Mucosa; Liver; Male; NAD(P)H Dehydrogenase (Quinone); NADP; Pyrazines; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 2003 |
Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo.
Topics: Animals; Basilar Artery; Catalase; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Hydrogen Peroxide; Hypertension; Male; NADP; NADPH Oxidase 4; NADPH Oxidases; Potassium Channel Blockers; Protein Subunits; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Species Specificity; Superoxide Dismutase; Superoxides; Vasodilation | 2004 |
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Catecholamines; Cell Cycle Proteins; Cerebellum; Corpus Striatum; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Dopamine; Mesencephalon; Mice; Mice, Knockout; NAD; NADP; Protein Serine-Threonine Kinases; Psychomotor Performance; Sex Factors; Tumor Suppressor Proteins | 2004 |
Involvement of oxidative stress in the profibrotic action of aldosterone. Interaction wtih the renin-angiotension system.
Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Biomarkers; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Endocardium; Endothelium, Vascular; Fibrosis; Infusions, Intra-Arterial; Kidney; Losartan; Male; Models, Cardiovascular; NADP; Nitroprusside; Oxidative Stress; Pericardium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels; Systole; Thiobarbituric Acid Reactive Substances; Vasodilator Agents | 2004 |
Hepatic arachidonic acid metabolism is disrupted after hexachlorobenzene treatment.
Topics: Animals; Arachidonic Acid; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Hexachlorobenzene; Hydroxyeicosatetraenoic Acids; Intubation, Gastrointestinal; Liver; Methods; Microsomes, Liver; NADP; Oxidoreductases; Phospholipases A; Phospholipases A2; Porphyrias, Hepatic; Prostaglandins E; Rats; Rats, Wistar; Time Factors | 2005 |
Aprotinin attenuated ischemia-reperfusion injury in an isolated rat lung model after 18-hours preservation.
Topics: Animals; Aprotinin; Cytokines; Disease Models, Animal; Gelatin; Lung; Lung Transplantation; Macrophages; Male; Malondialdehyde; NADP; Organ Preservation; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Serine Proteinase Inhibitors; Time Factors | 2005 |
Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult.
Topics: Animals; Brain Infarction; Calcium; Catalase; Cell Death; Disease Models, Animal; Hypothyroidism; Imidazoles; In Situ Nick-End Labeling; Lipid Peroxidation; Male; NADP; Neurologic Examination; Neuroprotective Agents; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Tetrazolium Salts | 2006 |
Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.
Topics: 6-Aminonicotinamide; Animals; Blood Pressure; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Heart Failure; Humans; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Superoxides; Teratogens; Time Factors | 2006 |
Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.
Topics: Aconitate Hydratase; Acute Kidney Injury; Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Calcium; Cardiolipins; Caspase 3; Cisplatin; Disease Models, Animal; Energy Metabolism; Enzyme Activation; Glutathione; Kidney; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; NADP; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Sulfhydryl Compounds | 2007 |
Melatonin pretreatment improves liver function and hepatic perfusion after hemorrhagic shock.
Topics: Animals; Disease Models, Animal; Indocyanine Green; Liver; Liver Circulation; Male; Melatonin; NADP; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic | 2008 |
Temporal window of metabolic brain vulnerability to concussions: mitochondrial-related impairment--part I.
Topics: Acetylation; Adenine Nucleotides; Amino Acids; Animals; Aspartic Acid; Brain; Brain Concussion; Coenzymes; Disease Models, Animal; Energy Metabolism; Glutamate Carboxypeptidase II; Male; Mitochondria; NADP; Nicotinic Acids; Rats; Rats, Wistar; Recurrence; RNA, Messenger; Severity of Illness Index; Time Factors | 2007 |
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
Topics: Age Factors; Animals; Antioxidants; Brain; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hydrogen Peroxide; Macrophages; Mice; Mice, Knockout; NADP; Oxidative Stress; Oxidoreductases; Protein Carbonylation; Reactive Oxygen Species; Subcellular Fractions; Thiobarbituric Acid Reactive Substances | 2007 |
Melatonin receptors mediate improvements of liver function but not of hepatic perfusion and integrity after hemorrhagic shock in rats.
Topics: Animals; Antioxidants; Coloring Agents; Disease Models, Animal; Indocyanine Green; Liver; Liver Function Tests; Male; Melatonin; Microcirculation; NADP; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Reference Values; Shock, Hemorrhagic; Treatment Outcome | 2008 |
7-nitroindazole attenuates 6-hydroxydopamine-induced spatial learning deficits and dopamine neuron loss in a presymptomatic animal model of Parkinson's disease.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dopamine; Indazoles; Learning Disabilities; Male; Maze Learning; NADP; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spatial Behavior; Substantia Nigra | 2008 |
[Exchange reactions in brain tissue under chronic ethanol intoxication].
Topics: Alcohol Oxidoreductases; Alcoholism; Animals; Brain; Citric Acid Cycle; Disease Models, Animal; Ethanol; Humans; NAD; NADP; Rabbits | 1982 |
Alkali burn-induced synthesis of inflammatory eicosanoids in rabbit corneal epithelium.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Burns, Chemical; Chromatography, High Pressure Liquid; Cornea; Corneal Neovascularization; Cytochrome P-450 Enzyme System; Disease Models, Animal; Epithelium; Eye Burns; Lipoxygenase; NADP; Rabbits; Sodium Hydroxide; Time Factors; Wound Healing | 1997 |
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E | 1998 |
Morphological changes of retinal pigment epithelium and choroid in rd-mice.
Topics: Animals; Choroid; Corrosion Casting; Disease Models, Animal; Histocytochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron; NADP; Pigment Epithelium of Eye; Retinal Degeneration | 1999 |
Altered mitochondrial oxidative phosphorylation in hippocampal slices of kainate-treated rats.
Topics: Animals; Benzimidazoles; Calcium; Chelating Agents; Coloring Agents; Disease Models, Animal; Egtazic Acid; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Mitochondria; NADP; Neurons; Organ Culture Techniques; Oxidative Phosphorylation; Oxygen Consumption; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sodium-Potassium-Exchanging ATPase; Uncoupling Agents | 1999 |
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Chromatography, High Pressure Liquid; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; GTP Cyclohydrolase; Immunoblotting; Kinetics; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Isoforms; Pteridines; Pterins; Rats; Rats, Mutant Strains | 2000 |
Interleukin-12 prevents diaphragm muscle deterioration in a septic animal model.
Topics: Adenosine Triphosphatases; Animals; Diaphragm; Disease Models, Animal; Electrophysiology; Endotoxins; Immunohistochemistry; Interleukin-12; Kinetics; Muscle Contraction; Muscle Fibers, Skeletal; Muscles; NADP; NADPH Dehydrogenase; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Time Factors | 2001 |
Regression of atherosclerosis in monkeys reduces vascular superoxide levels.
Topics: Acetylcholine; Animals; Arteries; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Dyes; Immunohistochemistry; In Vitro Techniques; Lipoproteins, LDL; Macaca fascicularis; Macrophages; Male; Membrane Transport Proteins; NADP; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Remission, Spontaneous; Superoxides; Vasomotor System | 2002 |
Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis.
Topics: Animals; Biopterins; Brain; Calcium; Calmodulin; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Flavin-Adenine Dinucleotide; Male; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; Rats; Rats, Inbred Lew; RNA, Messenger; Subcellular Fractions; Tyrosine | 2002 |
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Adhesion Molecules; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Infusions, Parenteral; Membrane Glycoproteins; Membrane Transport Proteins; Microfilament Proteins; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Dehydrogenase; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Protein Kinase C; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides; Vasodilation; Vasodilator Agents | 2002 |
Oxidative stress in a phenylketonuria animal model.
Topics: Animals; Brain; Catalase; Chromatography, High Pressure Liquid; Disease Models, Animal; Erythrocytes; Glucosephosphate Dehydrogenase; Glutathione; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Mice; Mice, Knockout; NADP; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylalanine; Phenylketonurias | 2002 |
Effects of G-6-PD deficiency, experimentally induced or genetically transmitted, on the sorbitol pathway activity. In vitro and in vivo studies.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Animals; Black People; Cataract; Child; Chloramphenicol; Costa Rica; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Erythrocytes; Galactosemias; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Humans; Incidence; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Male; Middle Aged; NADP; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sorbitol | 1992 |
Sepsis does not impair tricarboxylic acid cycle in the heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Citric Acid Cycle; Disease Models, Animal; Female; Heart; Heart Rate; Hematocrit; Magnetic Resonance Spectroscopy; Myocardium; NAD; NADP; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains; Reference Values; Sepsis | 1991 |
Regional bioenergetic events in the experimental glioblastoma. Aquantitative histochemical study.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Disease Models, Animal; Fluorometry; Freezing; Glioblastoma; Glucose; Glycogen; Histocytochemistry; Lactates; Mice; NAD; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Neuroglia; Oxygen Consumption; Pentoses; Phosphates; Phosphocreatine; Transplantation, Homologous | 1971 |
Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism.
Topics: Adaptation, Physiological; Animals; Bilirubin; Bone Marrow; Cycloheximide; Dactinomycin; Disease Models, Animal; Enzyme Induction; Female; Heme; Hemoglobins; Hemoglobinuria; Homeostasis; Injections, Intravenous; Iron Isotopes; Kidney Tubules; Liver; NADP; Oxygenases; Protein Biosynthesis; Puromycin; Rats; RNA; Spleen | 1971 |
Critical oxygen tensions in the brain.
Topics: Adenine Nucleotides; Animals; Brain; Brain Chemistry; Disease Models, Animal; Hypoxia; Lactates; NAD; NADP; Oxygen; Oxygen Consumption; Partial Pressure; Phosphocreatine; Pyruvates; Rats | 1971 |
6-Amnionicotinamide (6-AN) as a diabetogenic agent. In vitro and in vivo studies in the rat.
Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; NADP; Niacinamide; Pancreas; Pentosephosphates; Rats | 1972 |
Increased "malic enzyme" activity during adaptation to a low protein diet.
Topics: Adaptation, Physiological; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Dietary Proteins; Disease Models, Animal; Enzyme Induction; Glucosephosphate Dehydrogenase; Isocitrate Dehydrogenase; Kwashiorkor; Liver; Malate Dehydrogenase; Male; NADP; Protein Deficiency; Proteins; Rats | 1972 |