Page last updated: 2024-08-17

nadp and Chemical and Drug Induced Liver Injury

nadp has been researched along with Chemical and Drug Induced Liver Injury in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199033 (62.26)18.7374
1990's6 (11.32)18.2507
2000's7 (13.21)29.6817
2010's7 (13.21)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, X; Kaleri, NA; Li, J; Li, X; Sun, K; Wang, L; Zhang, W1
Jin, T; Liu, J; Shi, JS; Tao, N; Wu, Q; Zhang, D; Zhu, QN1
Guelfi, M; Maioli, MA; Medeiros, HC; Mingatto, FE; Moreira, PR; Pereira, FT1
Choi, JM; Jeon, JS; Kim, SK; Kim, YM; Lee, JY; Lee, K; Oh, SJ; Ryu, CS1
Horie, T; Ito, K; Sekine, S; Shirakawa, M; Tanaka, A1
Hashizume, T; Komuro, S; Mise, M; Usui, T; Yabuki, M1
Hu, Z; Li, S; Liao, M; Ma, H; Wang, Q; Wang, Y; Wu, C; Yang, B; Yuan, Y; Zheng, Z1
Adamska, T; Baer-Dubowska, W; Ignatowicz, E; Krajka-Kuźniak, V; Szaefer, H1
Andrés, D; Bautista, M; Cascales, M; Sánchez-Reus, I1
DINMAN, BD; FOX, CF; FRAJOLA, WJ; HAMDI, EA1
SLATER, TF2
Pashkov, AN; Popov, SS; Rakhmanova, TI; Semenikhina, AV1
Devaki, T; Raghavendran, HB; Sathivel, A1
Ikeda, T1
Dalvie, D; Deese, A; Kang, P; Smith, E; Zhou, S1
Macneil, DJ; Menetski, J; Mumick, S; Nizner, P; Qian, S; Reitman, ML; Tota, MR1
Kloss, MW; Rauckman, EJ; Rosen, GM1
Boroujerdi, M; Carlo, JR; Rosenbaum, SE1
Cavagnaro, J; Rauckman, EJ; Rosen, GM1
Chan, CH; James, JL; Moody, DE; Smuckler, EA1
Willis, RJ1
Atkinson, A; Meeks, RG; Roy, D1
Hamrick, ME; Harris, SR1
Dhawan, D; Goel, A1
Corcoran, GB; Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA1
Fujisawa, K; Kojima, M; Kurihara, N1
Cascales, F; Cascales, M; Cerdán, S; Chacón, P; Santos-Ruiz, A1
Khan, S; Lauriault, VV; O'Brien, PJ1
DeGray, JA; Mason, RP; Rao, DN1
Hartmann, HJ; Miesel, R; Weser, U1
Delaforge, M; Jaouen, M; Jollès, P; Mansuy, D; Migliore-Samour, D1
Kärki, NT; Keinänen, K; Saarni, HU; Sotaniemi, EA; Stenbäck, F; Stengård, JH1
Jatoe, SD; Lauriault, V; McGirr, LG; O'Brien, PJ1
Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC1
Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ1
Faeder, E; Fowler, BA; Hook, GE; Lucier, GW; McDaniel, OS; Sonawane, BR1
Carlson, GP; Fausto, N; Fuller, GC1
Sawyer, BC; Slater, TF; Sträuli, UD2
Apostolesco, I; Dobreanu-Enesco, V; Popesco, I; Velican, D; Zamfiresco-Gheorghiu, M1
Sawyer, BC; Slater, TF2
Leevy, CM1
Brody, TM; Gibb, JW1
Glende, EA; Recknagel, RO1
Khaĭkina, BI; Pavlova, II1
DeCarli, LM; Lieber, CS1
Brodie, BB; Cho, AK; Gillette, JR; Krishna, G; Reid, WD; Sipes, G1
Taketa, K; Watanabe, A1
Brodie, BB; Cho, AK; Krishna, G; Reid, WD1
Chopra, P; Nayak, NC; Ramalingaswami, V; Roy, S1
Gerdes, H; Littmann, KP; Spuck, W1

Reviews

3 review(s) available for nadp and Chemical and Drug Induced Liver Injury

ArticleYear
[Drug-induced liver injury].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:6

    Topics: Acetaminophen; Anesthetics, General; Animals; Benzoquinones; Chemical and Drug Induced Liver Injury; Chromans; Cytochrome P-450 CYP2E1; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Genetic Predisposition to Disease; Humans; Hypoglycemic Agents; Imines; NADP; Pharmacogenetics; Thiazolidinediones; Troglitazone

2006
Cocaine-mediated hepatotoxicity. A critical review.
    Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; Enzymes; Glutathione; Humans; Liver; NADP; Oxidation-Reduction

1984
[Hepatotoxicity of alcohol based on its metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 1976, Nov-10, Volume: 34, Issue:11

    Topics: Alcohol Oxidoreductases; Animals; Chemical and Drug Induced Liver Injury; Dietary Proteins; Ethanol; Fatty Liver; Humans; Liver; Mitochondria, Liver; NAD; NADP; Rats

1976

Other Studies

50 other study(ies) available for nadp and Chemical and Drug Induced Liver Injury

ArticleYear
Dietary Copper Reduces the Hepatotoxicity of (-)-Epigallocatechin-3-Gallate in Mice.
    Molecules (Basel, Switzerland), 2017, Dec-23, Volume: 23, Issue:1

    Topics: Animals; Antioxidants; Catechin; Ceruloplasmin; Chemical and Drug Induced Liver Injury; Copper; Glutathione Peroxidase; Glutathione Reductase; Liver; Male; Malondialdehyde; Mice, Inbred ICR; NADP; Oxidation-Reduction; Tea

2017
Induction of Nrf2 and metallothionein as a common mechanism of hepatoprotective medicinal herbs.
    The American journal of Chinese medicine, 2014, Volume: 42, Issue:1

    Topics: Acetaminophen; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Galactosamine; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; NAD(P)H Dehydrogenase (Quinone); NADP; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Piper; Plant Extracts

2014
Protective effect of bixin on carbon tetrachloride-induced hepatotoxicity in rats.
    Biological research, 2014, Sep-29, Volume: 47

    Topics: Animals; Antioxidants; Bixaceae; Carbon Tetrachloride; Carotenoids; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Reductase; Lipid Peroxidation; Liver; Male; Malondialdehyde; NADP; Oxidative Stress; Plant Extracts; Rats, Wistar; Reactive Oxygen Species; Transaminases

2014
Prediction of Drug-Induced Liver Injury in HepG2 Cells Cultured with Human Liver Microsomes.
    Chemical research in toxicology, 2015, May-18, Volume: 28, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Hep G2 Cells; Humans; Liver; Microsomes, Liver; NADP

2015
Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition.
    Toxicology and applied pharmacology, 2015, Oct-01, Volume: 288, Issue:1

    Topics: Activation, Metabolic; Animals; Benzbromarone; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme System; Kinetics; Liver; Male; Membrane Potential, Mitochondrial; Microsomes, Liver; Mitochondria, Liver; Mitochondrial Swelling; NADP; Rats, Sprague-Dawley

2015
Evaluation of the potential for drug-induced liver injury based on in vitro covalent binding to human liver proteins.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glucuronic Acid; Glucuronosyltransferase; Glutathione; Hepatocytes; Humans; Liver; Metabolomics; Microsomes, Liver; NADP; Protein Binding; Reproducibility of Results; Risk Assessment; Risk Factors

2009
Plasma and liver proteomic analysis of 3Z-3-[(1H-pyrrol-2-yl)-methylidene]-1-(1-piperidinylmethyl)-1,3-2H-indol-2-one-induced hepatotoxicity in Wistar rats.
    Proteomics, 2010, Volume: 10, Issue:16

    Topics: Amino Acids; Animals; Apoptosis; Blood Proteins; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Female; Histocytochemistry; In Situ Nick-End Labeling; Liver; Mass Spectrometry; Mesylates; NADP; Proteome; Proteomics; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species

2010
Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:6

    Topics: Alkylating Agents; Animals; Beta vulgaris; Beverages; Blotting, Western; Chemical and Drug Induced Liver Injury; Comet Assay; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytosol; Diethylnitrosamine; DNA Damage; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Male; Microsomes, Liver; NADP; Proteins; Rats; Rats, Wistar

2012
Depletion of Kupffer cell function by gadolinium chloride attenuates thioacetamide-induced hepatotoxicity. Expression of metallothionein and HSP70.
    Biochemical pharmacology, 2003, Sep-15, Volume: 66, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Biotransformation; Chemical and Drug Induced Liver Injury; Drug Interactions; Gadolinium; Gene Expression; HSP70 Heat-Shock Proteins; Kupffer Cells; Male; Metallothionein; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidative Stress; Rats; Rats, Wistar; Thioacetamide

2003
CCI4 TOXICITY. III. HEPATO-STRUCTURAL AND ENZYMATIC CHANGE.
    Archives of environmental health, 1963, Volume: 7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Hepatitis; Liver; Microscopy; NADP; Oxidoreductases; Rabbits; Research

1963
A NOTE ON THE RELATIVE TOXIC ACTIVITIES OF TETRACHLOROMETHANE AND TRICHLORO-FLUORO-METHANE ON THE RAT.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Chloroform; Fluorides; Glucuronidase; Hepatitis; Methane; NADP; Necrosis; Rats; Research; Solvents; Toxicology

1965
Glutathione system and activity of NADPH-generating enzymes in the liver of intact rats and animals with toxic hepatitis receiving melatonin.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Isocitrate Dehydrogenase; Liver; Male; Melatonin; NADP; Oxidation-Reduction; Rats

2005
Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.
    World journal of gastroenterology, 2006, Jun-28, Volume: 12, Issue:24

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Cytochrome-B(5) Reductase; Endoplasmic Reticulum; Imines; Inactivation, Metabolic; Liver; Magnetic Resonance Spectroscopy; Male; Microscopy, Electron; Microsomes, Liver; Mitochondria; NADP; NADPH-Ferrihemoprotein Reductase; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Sargassum; Tumor Necrosis Factor-alpha

2006
Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Flutamide; Glutathione; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; NADP; Recombinant Proteins; Tandem Mass Spectrometry

2007
Deficiency in cytosolic malic enzyme does not increase acetaminophen-induced hepato-toxicity.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Chemical and Drug Induced Liver Injury; Cytosol; Genotype; Glutathione; Liver; Malate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NADP

2008
Protective action of 2(3)-tert-butyl-4-hydroxyanisole (BHA) on acetaminophen-induced liver necrosis in male A/J mice.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3

    Topics: Acetaminophen; Animals; Anisoles; Butylated Hydroxyanisole; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Liver Diseases; Male; Mice; Mice, Inbred A; Microsomes, Liver; NADP; Necrosis; Protein Binding

1984
Norcocaine nitroxide. A potential hepatotoxic metabolite of cocaine.
    Molecular pharmacology, 1982, Volume: 21, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cocaine; In Vitro Techniques; Kinetics; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344

1982
The phospholipids of the hepatic endoplasmic reticulum. Structural change in liver injury.
    The Biochemical journal, 1982, Aug-15, Volume: 206, Issue:2

    Topics: Adenosine Diphosphate; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorides; Endoplasmic Reticulum; Ferric Compounds; Liver; Liver Diseases; Male; Microsomes, Liver; NADP; Phosphatidic Acids; Rats; Rats, Inbred Strains

1982
Possible role of endogenous toxigenic lipids in the carbon tetrachloride poisoned hepatocyte.
    Federation proceedings, 1980, Volume: 39, Issue:13

    Topics: Biotransformation; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Free Radicals; Membrane Lipids; Microsomes, Liver; NADP; Peroxides

1980
Increased oxidative stress in the liver of mice treated with trichloroethylene.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Clofibrate; Liver; Male; Malondialdehyde; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Trichloroacetic Acid; Trichloroethylene

1993
Antagonism of acetaminophen hepatotoxicity by phospholipase A2 inhibitors.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 79, Issue:1

    Topics: Acetaminophen; Animals; Calcium; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlorpromazine; Diltiazem; DNA; Homeostasis; Male; Mice; Mitochondria, Liver; NADP; Oxidation-Reduction; Phospholipases A; Phospholipases A2

1993
Further evidence for zinc as a hepatoprotective agent in rat liver toxicity.
    Experimental and molecular pathology, 1995, Volume: 63, Issue:2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Mixed Function Oxygenases; NADP; Rats; Zinc

1995
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat.
    Science (New York, N.Y.), 1976, Sep-03, Volume: 193, Issue:4256

    Topics: Animals; Chemical and Drug Induced Liver Injury; Humans; Hydrazines; Iproniazid; Isoniazid; Microsomes, Liver; NADP; Rats; Structure-Activity Relationship

1976
Hepatotoxic effect of thioacetamide (TAM) on NADP-linked enzymes, aminotransferases and glutamate dehydrogenase.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1978, Issue:1

    Topics: Acetamides; Alanine Transaminase; Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutamate Dehydrogenase; Male; NADP; Rats; Thioacetamide; Transaminases

1978
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
    Chemico-biological interactions, 1992, Volume: 81, Issue:3

    Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains

1992
Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes.
    Archives of biochemistry and biophysics, 1991, Aug-15, Volume: 289, Issue:1

    Topics: Animals; Benzyl Viologen; Cations; Chemical and Drug Induced Liver Injury; Cobalt; Cytochrome P-450 Enzyme System; Diquat; Electron Spin Resonance Spectroscopy; Free Radicals; Liver; Male; Metyrapone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat; Pentetic Acid; Pyridinium Compounds; Rats

1991
Antiinflammatory reactivity of copper(I)-thionein.
    Inflammation, 1990, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Chemical and Drug Induced Liver Injury; Ficusin; Free Radicals; Inflammation; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Male; Metallothionein; Mice; NADP; Neutrophils; Oxygen; Phagocytosis; Singlet Oxygen; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1990
In vivo effects of immunostimulating lipopeptides on mouse liver microsomal cytochromes P-450 and on paracetamol-induced toxicity.
    Experientia, 1989, Sep-15, Volume: 45, Issue:9

    Topics: Acetaminophen; Adjuvants, Immunologic; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Lipid Peroxidation; Liver Diseases; Mice; Microsomes, Liver; NADP; Oligopeptides; Pimelic Acids

1989
Medroxyprogesterone acetate and phenobarbital induce NADPH producing enzyme activities in rats with a chemical liver injury.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 50, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Enzyme Induction; Glucose-6-Phosphatase; Isocitrate Dehydrogenase; Malate Dehydrogenase; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; NADP; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains

1985
The toxicity of disulphides to isolated hepatocytes and mitochondria.
    Drug metabolism and drug interactions, 1988, Volume: 6, Issue:3-4

    Topics: Adenosine Triphosphate; Animals; Calcium; Chemical and Drug Induced Liver Injury; Cystamine; Disulfides; Dithiothreitol; In Vitro Techniques; Liver; Male; Membrane Potentials; Mitochondria; Mitochondria, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains

1988
Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:8

    Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Halothane; Hyperthyroidism; Lipid Metabolism; Male; Microsomes, Liver; NADP; Phenobarbital; Proteins; Pyridines; Rats; Rats, Inbred Strains; Triiodothyronine

1988
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1

    Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium

1973
TCDD-induced changes in rat liver microsomal enzymes.
    Environmental health perspectives, 1973, Volume: 5

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Chemical and Drug Induced Liver Injury; Chlorobenzenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dioxins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Glucuronidase; Glucuronosyltransferase; Hydroxylation; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NADP; Oxidative Phosphorylation; Proteins; Rats

1973
Effects of spironolactone on carbon tetrachloride hepatotoxicity.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:1

    Topics: Alanine Transaminase; Aldehydes; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Glucose-6-Phosphatase; Male; Malonates; Microsomes, Liver; NADP; Rats; Spironolactone

1974
Changes in liver nucleotide concentrations in experimental liver injury. 1. Carbon tetrachloride poisoning.
    The Biochemical journal, 1964, Volume: 93, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Liver; NAD; NADP; Necrosis; Paraffin; Promethazine; Rats

1964
Changes in liver nucleotide concentrations in experimental liver injury. 2. Acute ethanol poisoning.
    The Biochemical journal, 1964, Volume: 93, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Liver; NAD; NADP; Rats

1964
Contributions to the study of certain energy-producing intracellular enzymes during chronic experimental hepatitis.
    Folia histochemica et cytochemica, 1966, Volume: 4, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Histocytochemistry; NAD; NADP; Oxidoreductases; Rabbits

1966
Liver nucleotides in acute experimental liver injury induced by dimethylnitrosamine and by thioacetamide.
    The Biochemical journal, 1966, Volume: 101, Issue:1

    Topics: Amides; Animals; Chemical and Drug Induced Liver Injury; Female; Liver; NAD; NADP; Nitrosamines; Rats; Sulfhydryl Compounds

1966
Nicotinamide-adenine dinucleotides in acute liver injury induced by ethionine, and a comparison with the effects of salicylate.
    The Biochemical journal, 1966, Volume: 101, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Ethionine; Female; Liver; NAD; NADP; Rats; Sodium Salicylate

1966
Clinical diagnosis, evaluation and treatment of liver disease in in alcoholics.
    Federation proceedings, 1967, Volume: 26, Issue:5

    Topics: Alcoholism; Blood Glucose; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Liver; Humans; Lactates; Liver Diseases; NAD; NADP; Organ Size

1967
The protective effect of nicotinamide on carbon tetrachloride-induced hepatotoxicity.
    Biochemical pharmacology, 1967, Volume: 16, Issue:10

    Topics: Animals; Antidotes; Body Temperature; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Liver; Mitochondria, Liver; NAD; NADP; Niacinamide; Rats; Temperature

1967
The inhibitory effects in vitro of phenothiazines and other drugs on lipid-peroxidation systems in rat liver microsomes, and their relationship to the liver necrosis produced by carbon tetrachloride.
    The Biochemical journal, 1968, Volume: 106, Issue:1

    Topics: Adenine Nucleotides; Animals; Animals, Newborn; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chickens; Depression, Chemical; Female; Iron; Lipid Metabolism; Liver; Microsomes; NADP; Oxygen Consumption; Peroxides; Phenols; Phenothiazines; Promethazine; Rats; Stimulation, Chemical; Succinates; Sulfites; Temperature; Trifluoperazine

1968
Biochemical basis for the in vitro pro-oxidant action of carbon tetrachloride.
    Experimental and molecular pathology, 1969, Volume: 11, Issue:2

    Topics: Aldehydes; Animals; Antimetabolites; Benzene; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochromes; Edetic Acid; Electron Transport; Ferricyanides; Glutathione; Lipid Metabolism; Male; Malonates; Methane; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1969
[Distribution characteristics of nicotinamide coenzymes (NAD and NADP) in the cellular structures of the liver and brain following administration of DDT].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:1

    Topics: Animals; Brain; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cytoplasm; DDT; Fluorometry; Liver; Male; Mitochondria; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Rats

1970
Reduced nicotinamide-adenine dinucleotide phosphate oxidase: activity enhanced by ethanol consumption.
    Science (New York, N.Y.), 1970, Oct-02, Volume: 170, Issue:3953

    Topics: Alcohol Drinking; Animals; Catalase; Chemical and Drug Induced Liver Injury; Ethanol; Female; Hydrogen Peroxide; Male; Microsomes, Liver; NADP; Oxidoreductases; Rats; Stimulation, Chemical

1970
Possible mechanism of liver necrosis caused by aromatic organic compounds.
    Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:1

    Topics: Animals; Autoradiography; Benzene Derivatives; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Chromatography, Paper; Drug Synergism; Glutathione; Hydrocarbons, Halogenated; Liver; Liver Diseases; Male; Microsomes, Liver; NADP; Naphthalenes; Necrosis; Phenobarbital; Rats

1971
Interconvertible microheterogeneity of glucose-6-phosphate dehydrogenase in rat liver.
    Biochimica et biophysica acta, 1971, Apr-14, Volume: 235, Issue:1

    Topics: Acrylates; Animals; Carbon Tetrachloride Poisoning; Cattle; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlorides; Drug Stability; Electrophoresis, Disc; Glucosephosphate Dehydrogenase; Hemoglobins; Kidney; Liver; Male; Mercaptoethanol; Mercury; Molecular Weight; Muscles; NADP; Rats; Solubility; Spectrophotometry; Time Factors

1971
Drug metabolism in man: past, present, and future.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Aerobiosis; Alkylating Agents; Allyl Compounds; Animals; Autoradiography; Bromine; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Paper; Ethers, Cyclic; Glutathione; Hydrocarbons, Halogenated; Iodine; Liver; Male; Mice; Microsomes, Liver; Models, Biological; NADP; Necrosis; Phenobarbital; Rats; Sheep; Sulfur Isotopes

1971
Mechanism of carbon tetrachloride hepatotoxicity. An in vivo study of its molecular basis in rats and monkeys.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 26, Issue:6

    Topics: Aniline Compounds; Animals; Biopsy; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electron Transport; Endoplasmic Reticulum; Ethionine; Fatty Liver; Glucose-6-Phosphatase; Histocytochemistry; Liver; Macaca; Male; Microsomes, Liver; NADP; Necrosis; Oxidoreductases; Phenazines; Phenobarbital; Proadifen; Protein Deficiency; Rats; Rats, Inbred Strains

1972
[Effect of experimental liver damage on the reduction of testosterone and 4-androstene-3,17-dione].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1972, Volume: 157, Issue:2

    Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethanol; In Vitro Techniques; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Testosterone

1972