Compounds > nadp
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nadp and Astrocytoma, Grade IV

nadp has been researched along with Astrocytoma, Grade IV in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19905 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's11 (55.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Jankowski, CSR; Rabinowitz, JD1
Condro, M; Kornblum, HI; Le Belle, JE; Ludwig, K; Muthukrishnan, SD; Pajonk, F; Sperry, J; Vlashi, E1
Bartom, E; Bi, Y; Burant, CF; Calvert, AE; Chalastanis, A; Chandel, NS; Davuluri, RV; Dubrovskyi, O; Horbinski, C; Hua, Y; Hurley, LA; James, CD; Kachman, M; Kouri, FM; May, JL; Mazar, AP; Mishra, RK; Peter, ME; Schiltz, GE; Stegh, AH; Wu, Y; Zheng, H1
Cho, HR; Choi, A; Choi, H; Choi, SH; Chowdhury, T; Dho, YS; Hwang, T; Kim, DG; Kim, H; Kim, HC; Kim, JE; Kim, JI; Kim, JW; Kim, S; Kim, SK; Kim, YH; Lee, SH; Park, CK; Park, S; Park, SH; Seo, Y; Shin, JY; Xu, WJ1
Goji, T; Katoh, H; Negishi, M; Takahara, K1
Gao, H; Li, W; Liang, J; Liu, R; Tao, B; Wang, C; Wang, X; Yang, W; Yang, Z; Zhang, Y1
Chen, J; Cui, D; Gong, M; Gong, P; Ni, L; Nie, D; Shi, J; Shi, W; Xia, L; Zhao, L; Zuo, H1
Bleeker, FE; Botman, D; Dimitrakopoulou, D; Henneman, P; Hira, VV; Hoebe, RA; Khurshed, M; Leenders, WP; Lenting, K; Maciejewski, JP; Molenaar, RJ; Mul, AN; Radivoyevitch, T; Smits, MA; Stap, J; van Drunen, CM; van Lith, SA; van Noorden, CJ; Vandertop, WP; Wilmink, JW1
Burant, CF; Davis, M; Dresser, J; Feng, FY; Kachman, M; Lawrence, TS; Lyssiotis, CA; Morgan, MA; Parsels, JD; Speers, C; Wahl, DR; Wernisch, S; Wilder-Romans, K; Zhao, L; Zhao, SG1
Pollard, PJ; Ratcliffe, PJ1
Atai, NA; Bardelli, A; Bleeker, FE; Bosch, KS; Jonker, A; Lamba, S; Rijkeboer, D; Tigchelaar, W; Troost, D; Van Noorden, CJ; Vandertop, WP1
Reitman, ZJ; Yan, H1
Atai, NA; Bjerkvig, R; Bleeker, FE; Bosch, KS; Bosman, J; De Witt Hamer, PC; Jonker, A; Miletic, H; Renkema-Mills, NA; Rijkeboer, D; Schmidt, N; Tigchelaar, W; Troost, D; Van Noorden, CJ1
Croteau, NJ; Ferrick, DA; Pike, LS; Smift, AL; Wu, M1
FABIANI, A; SCHIFFER, D; VESCO, C1
MUELLER, W; NASU, H1
Arscott, LD; Ballou, DP; Becker, K; Davioud-Charvet, E; Deponte, M; Fritz-Wolf, K; Herold-Mende, C; Koncarevic, S; Meyer, M; Réau, R; Urig, S; Williams, CH1
Coper, H1
Kirsch, WM; Leitner, JW; Schulz, D1
Kirsch, WM; Schulz, DW1

Reviews

1 review(s) available for nadp and Astrocytoma, Grade IV

ArticleYear
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
    Journal of the National Cancer Institute, 2010, Jul-07, Volume: 102, Issue:13

    Topics: Animals; Arginine; Brain Neoplasms; Codon; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Glucose; Glutarates; Humans; Hypoxia; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Oligodendroglioma; Oncogenes; Signal Transduction; Up-Regulation

2010

Trials

1 trial(s) available for nadp and Astrocytoma, Grade IV

ArticleYear
[Studies of the NAD(P) glycohydrolase activity in human brain tumors].
    Zeitschrift fur Krebsforschung, 1967, Volume: 70, Issue:2

    Topics: Adenoma, Chromophobe; Astrocytoma; Brain Neoplasms; Clinical Trials as Topic; Enzyme Induction; Ependymoma; Glioblastoma; Glioma; Glycoside Hydrolases; Humans; NADP; Niacinamide; Paraganglioma; Pituitary Neoplasms

1967

Other Studies

18 other study(ies) available for nadp and Astrocytoma, Grade IV

ArticleYear
Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate.
    Cancer research, 2022, Oct-04, Volume: 82, Issue:19

    Topics: Animals; Antioxidants; Ascorbic Acid; Glioblastoma; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Mice; NADP; Reactive Oxygen Species; Selenium; Selenoproteins

2022
Nicotinamide Adenine Dinucleotide Phosphate Oxidase Promotes Glioblastoma Radiation Resistance in a Phosphate and Tensin Homolog-Dependent Manner.
    Antioxidants & redox signaling, 2023, Volume: 39, Issue:13-15

    Topics: Brain Neoplasms; Glioblastoma; Humans; Hypoxia; NADP; NADPH Oxidases; Phosphates; Reactive Oxygen Species; Tensins

2023
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.
    Cell reports, 2017, 05-30, Volume: 19, Issue:9

    Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Histones; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lipids; Methylation; Mice; Mice, SCID; Molecular Targeted Therapy; Mutation; NADP; Neoplastic Stem Cells; Protein Kinase Inhibitors; Reactive Oxygen Species; RNA, Messenger

2017
Glutaminase 2 expression is associated with regional heterogeneity of 5-aminolevulinic acid fluorescence in glioblastoma.
    Scientific reports, 2017, 09-22, Volume: 7, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Fluorescence; Fluorescent Dyes; Gene Expression Profiling; Glioblastoma; Glutaminase; Humans; Levulinic Acids; NADP; Prospective Studies; Protoporphyrins; Surgery, Computer-Assisted

2017
Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation.
    The Journal of biological chemistry, 2017, 12-01, Volume: 292, Issue:48

    Topics: Amino Acid Transport Systems, Acidic; Animals; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cystine; Glioblastoma; Glucose; NADP; Rats; Reactive Oxygen Species

2017
Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.
    Nature communications, 2019, 03-01, Volume: 10, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; HEK293 Cells; Humans; Kinetics; Mice; Mice, Nude; Models, Molecular; NADP; Neoplasms; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Phosphorylation; Radiation, Ionizing; Reactive Oxygen Species; Ribosemonophosphates; Tyrosine; Up-Regulation

2019
An IDH1 mutation inhibits growth of glioma cells via GSH depletion and ROS generation.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:6

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Glutathione; Humans; Isocitrate Dehydrogenase; Mutation; NADP; Reactive Oxygen Species

2014
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
    Cancer research, 2015, Nov-15, Volume: 75, Issue:22

    Topics: Antineoplastic Agents; Benzeneacetamides; Blotting, Western; Cell Line, Tumor; Chemoradiotherapy; DNA Methylation; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Knock-In Techniques; Glioblastoma; Humans; Imidazoles; In Vitro Techniques; Isocitrate Dehydrogenase; Mutation; NADP; Oxidative Stress; Radiation Tolerance

2015
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
    Cancer research, 2017, 02-15, Volume: 77, Issue:4

    Topics: Acetylcysteine; Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Mice; NADP; Radiation Tolerance; Xenograft Model Antitumor Assays

2017
Cancer. Puzzling patterns of predisposition.
    Science (New York, N.Y.), 2009, Apr-10, Volume: 324, Issue:5924

    Topics: Amino Acid Substitution; Arginine; Brain Neoplasms; Citric Acid Cycle; Dinucleoside Phosphates; Fumarate Hydratase; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Glioblastoma; Glutamates; Humans; Hydroxylation; Hypoxia-Inducible Factor 1; Isocitrate Dehydrogenase; Mutation; NADP; Oncogenes; Succinate Dehydrogenase

2009
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.
    Acta neuropathologica, 2010, Volume: 119, Issue:4

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Amino Acid Substitution; Drug Therapy; Enzyme Assays; Female; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation; NADP; Oxidoreductases; Prognosis; Radiotherapy; Survival Analysis

2010
Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2011, Volume: 59, Issue:5

    Topics: Animals; Brain; Brain Neoplasms; Glioblastoma; Humans; Isocitrate Dehydrogenase; Mice; Mice, Inbred C57BL; Models, Animal; Mutation; NADP; Oxidoreductases; Rats; Rats, Nude

2011
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.
    Biochimica et biophysica acta, 2011, Volume: 1807, Issue:6

    Topics: Adenosine Triphosphate; Brain Neoplasms; Cell Death; Down-Regulation; Drug Evaluation, Preclinical; Epoxy Compounds; Fatty Acids; Glioblastoma; Humans; Hypoglycemic Agents; Models, Biological; NADP; Oxidation-Reduction; Reactive Oxygen Species; Tumor Cells, Cultured; Up-Regulation

2011
HISTOCHEMICAL STUDY OF ROSENTHAL FIBRES, WITH OBSERVATIONS ABOUT SOME ENZYME ACTIVITIES.
    Psychiatria et neurologia, 1964, Volume: 147

    Topics: Acid Phosphatase; Adenosine Triphosphate; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; Dihydrolipoamide Dehydrogenase; Electron Transport Complex II; Ependyma; Esterases; Glioblastoma; Glucose-6-Phosphatase; Hemangiosarcoma; Histocytochemistry; Intracranial Arteriosclerosis; L-Lactate Dehydrogenase; NAD; NADP; Oligodendroglioma; Succinate Dehydrogenase

1964
[ENZYME HISTOCHEMICAL STUDIES ON GLIOMA].
    Deutsche Zeitschrift fur Nervenheilkunde, 1964, Apr-23, Volume: 186

    Topics: Acid Phosphatase; Alkaline Phosphatase; Astrocytoma; Brain; Brain Neoplasms; Esterases; Glioblastoma; Glioma; NAD; NADP; Neurochemistry; Oligodendroglioma; Oxidoreductases

1964
Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase.
    The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21

    Topics: Binding Sites; Borohydrides; Cell Division; Cysteine; Enzyme Inhibitors; Glioblastoma; Glutathione; Glutathione Reductase; Humans; Kinetics; Mass Spectrometry; Models, Molecular; NADP; Organometallic Compounds; Organophosphorus Compounds; Oxidation-Reduction; Recombinant Proteins; Tumor Cells, Cultured

2005
The quantitative histochemistry of the experimental glioblastoma: glycolysis and growth.
    Acta histochemica, 1967, Volume: 28, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Creatine Kinase; Glioblastoma; Glucose; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glutamate Dehydrogenase; Glycogen; Glycolysis; Hexokinase; Histocytochemistry; Ischemia; Lactates; Mice; NAD; NADP; Neoplasms, Experimental; Phosphates; Phosphocreatine; Phosphoglucomutase; Phosphogluconate Dehydrogenase

1967
Regional bioenergetic events in the experimental glioblastoma. Aquantitative histochemical study.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Disease Models, Animal; Fluorometry; Freezing; Glioblastoma; Glucose; Glycogen; Histocytochemistry; Lactates; Mice; NAD; NADP; Neoplasm Transplantation; Neoplasms, Experimental; Neuroglia; Oxygen Consumption; Pentoses; Phosphates; Phosphocreatine; Transplantation, Homologous

1971