Page last updated: 2024-08-17

nad and Wallerian Degeneration

nad has been researched along with Wallerian Degeneration in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (27.27)29.6817
2010's11 (50.00)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Sun, YY; Wu, YJ1
Chen, X; Gao, M; Hu, C; Li, W; Zhou, Y1
Coleman, MP; Höke, A1
DiAntonio, A; Figley, MD1
Loring, HS; Mondal, S; Parelkar, SS; Thompson, PR1
Sasaki, Y1
Heiland, I; Niere, M; Nikiforov, AA; Strømland, Ø; VanLinden, MR; Ziegler, M1
Bobba, N; Calliari, A; Chini, EN; Escande, C1
Brace, EJ; DiAntonio, A; Gerdts, J; Milbrandt, J; Sasaki, Y1
DiAntonio, A; Gerdts, J; Milbrandt, J; Summers, DW1
Chang, B; Lu, S; Peng, J; Quan, Q; Wang, Y1
Bramley, JC; Buchser, WJ; Clark, KB; Collins, SV1
Feng, Y; Ge, X; Wu, D; Yan, T; Zhai, Q; Zhang, Y; Zhao, J; Zheng, J1
Bendotti, C; Cialabrini, L; Coleman, M; Conforti, L; Di Stefano, M; Janeckova, L; Magni, G; Mazzola, F; Orsomando, G; Smyth, N; Wagner, D1
Antenor-Dorsey, JA; O'Malley, KL1
Barrientos, A; Liu, J; Ocampo, A1
Bedalov, A; Simon, JA1
Araki, T; Milbrandt, J; Sasaki, Y1
Chen, Y; Gu, W; He, Z; Lin, E; McBurney, MW; Wang, J; Zhai, Q1
Adalbert, R; Asress, S; Beirowski, B; Bridge, K; Coleman, MP; Conforti, L; Fang, G; Glass, JD; Huang, XP; Magni, G; Silva, A; Sorci, L; Wang, MS1
Chitnis, T; He, Z; Hurrell, JM; Kaneko, M; Kaneko, S; Khoury, SJ; Wang, J; Yiu, G1
Bellen, HJ; Cao, Y; Hiesinger, PR; Mehta, SQ; Schulze, KL; Verstreken, P; Zhai, RG; Zhou, Y1

Reviews

7 review(s) available for nad and Wallerian Degeneration

ArticleYear
NMNAT2: An important metabolic enzyme affecting the disease progression.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 158

    Topics: Axons; Disease Progression; Humans; NAD; Neurodegenerative Diseases; Nicotinamide-Nucleotide Adenylyltransferase; Wallerian Degeneration

2023
Programmed axon degeneration: from mouse to mechanism to medicine.
    Nature reviews. Neuroscience, 2020, Volume: 21, Issue:4

    Topics: Animals; Armadillo Domain Proteins; Cytoskeletal Proteins; Disease Models, Animal; Drosophila melanogaster; Humans; Mice; Mice, Transgenic; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Signal Transduction; Translational Research, Biomedical; Wallerian Degeneration

2020
The SARM1 axon degeneration pathway: control of the NAD
    Current opinion in neurobiology, 2020, Volume: 63

    Topics: Armadillo Domain Proteins; Axons; Cytoskeletal Proteins; Humans; Metabolome; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Wallerian Degeneration

2020
Metabolic aspects of neuronal degeneration: From a NAD
    Neuroscience research, 2019, Volume: 139

    Topics: Animals; Axons; Cell Death; Humans; NAD; Nerve Tissue Proteins; Neurons; Wallerian Degeneration

2019
Keeping the balance in NAD metabolism.
    Biochemical Society transactions, 2019, 02-28, Volume: 47, Issue:1

    Topics: ADP-Ribosylation; Animals; Humans; NAD; Signal Transduction; Sirtuins; Wallerian Degeneration

2019
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
    Neuron, 2016, Feb-03, Volume: 89, Issue:3

    Topics: Animals; Armadillo Domain Proteins; Axons; Cytoskeletal Proteins; Humans; Mitogen-Activated Protein Kinases; NAD; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Signal Transduction; Wallerian Degeneration

2016
Molecular mechanisms in the initiation phase of Wallerian degeneration.
    The European journal of neuroscience, 2016, Volume: 44, Issue:4

    Topics: Animals; Axons; Humans; NAD; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Wallerian Degeneration

2016

Other Studies

15 other study(ies) available for nad and Wallerian Degeneration

ArticleYear
Tri-ortho-cresyl phosphate induces axonal degeneration in chicken DRG neurons by the NAD+ pathway.
    Toxicology letters, 2022, Jun-15, Volume: 363

    Topics: Adenosine Triphosphate; Animals; Axons; Chickens; Ganglia, Spinal; NAD; Neurons; Organophosphates; Peripheral Nervous System Diseases; Phosphates; Tritolyl Phosphates; Wallerian Degeneration

2022
Identification of the first noncompetitive SARM1 inhibitors.
    Bioorganic & medicinal chemistry, 2020, 09-15, Volume: 28, Issue:18

    Topics: Amino Acid Motifs; Amino Acid Sequence; Armadillo Domain Proteins; Axons; Berberine; Binding Sites; Catalysis; Chlorides; Cytoskeletal Proteins; Gene Knockdown Techniques; High-Throughput Screening Assays; Humans; Hydrolases; Mutagenesis; NAD; Niacinamide; Protein Binding; Wallerian Degeneration; Zinc Compounds

2020
Resveratrol delays Wallerian degeneration in a NAD(+) and DBC1 dependent manner.
    Experimental neurology, 2014, Volume: 251

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal; Humans; In Vitro Techniques; Mice; NAD; Neurofilament Proteins; Neurons; Resveratrol; RNA-Binding Proteins; Sciatic Nerve; Sirtuin 1; Stilbenes; Time Factors; Transfection; Wallerian Degeneration

2014
SARM1 activation triggers axon degeneration locally via NAD⁺ destruction.
    Science (New York, N.Y.), 2015, Apr-24, Volume: 348, Issue:6233

    Topics: Animals; Armadillo Domain Proteins; Axons; Cytoskeletal Proteins; HEK293 Cells; Humans; Mice; Mice, Knockout; NAD; Neurons; Peripheral Nerve Injuries; Protein Multimerization; Wallerian Degeneration

2015
Avian axons undergo Wallerian degeneration after injury and stress.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2016, Volume: 202, Issue:11

    Topics: Analysis of Variance; Animals; Axons; Axotomy; Calcium; Cells, Cultured; Disease Models, Animal; Finches; Microscopy, Confocal; Microscopy, Fluorescence; NAD; Nerve Degeneration; Paclitaxel; Pressure; Retinal Ganglion Cells; Stress, Physiological; Vincristine; Wallerian Degeneration

2016
Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.
    Neurochemistry international, 2010, Volume: 56, Issue:1

    Topics: Animals; Axons; Cell Death; Cell Line; Cells, Cultured; Cytoprotection; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubules; NAD; Neurofilament Proteins; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Time Factors; Wallerian Degeneration

2010
Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration.
    The FEBS journal, 2011, Volume: 278, Issue:15

    Topics: Animals; Axons; Gene Targeting; Mice; Mice, Knockout; NAD; Nerve Tissue Proteins; Nicotinamide-Nucleotide Adenylyltransferase; Wallerian Degeneration

2011
WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity.
    Molecular neurodegeneration, 2012, Feb-08, Volume: 7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Axons; Cells, Cultured; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; NAD; Nerve Tissue Proteins; Neurites; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Parkinson Disease; Wallerian Degeneration

2012
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins.
    Human molecular genetics, 2013, May-01, Volume: 22, Issue:9

    Topics: alpha-Synuclein; Gene Expression; Histone Deacetylases; Mitochondria; NAD; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Oxidative Phosphorylation; Peptides; Protein Folding; Saccharomyces cerevisiae; Wallerian Degeneration

2013
Neuroscience. NAD to the rescue.
    Science (New York, N.Y.), 2004, Aug-13, Volume: 305, Issue:5686

    Topics: Animals; Axons; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Mice; Mutation; NAD; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; RNA, Small Interfering; Sirtuin 1; Sirtuins; Ubiquitin-Protein Ligases; Wallerian Degeneration

2004
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
    Science (New York, N.Y.), 2004, Aug-13, Volume: 305, Issue:5686

    Topics: 3T3 Cells; Animals; Axons; Axotomy; Benzamides; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Humans; Lentivirus; Mice; Mutation; NAD; Naphthols; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes; Ubiquitin-Protein Ligases; Vincristine; Wallerian Degeneration

2004
A local mechanism mediates NAD-dependent protection of axon degeneration.
    The Journal of cell biology, 2005, Aug-01, Volume: 170, Issue:3

    Topics: Adenosine Triphosphate; Animals; Axons; Cells, Cultured; Mice; NAD; Nerve Tissue Proteins; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Recombinant Fusion Proteins; Sirtuin 1; Sirtuins; Wallerian Degeneration

2005
NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration.
    Cell death and differentiation, 2007, Volume: 14, Issue:1

    Topics: Animals; Axons; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAD; Nerve Tissue Proteins; Nicotinamide-Nucleotide Adenylyltransferase; Point Mutation; Resveratrol; Sciatic Neuropathy; Stilbenes; Wallerian Degeneration

2007
Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-20, Volume: 26, Issue:38

    Topics: Animals; Axons; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Multiple Sclerosis; NAD; Nerve Degeneration; Neuroprotective Agents; Rats; Wallerian Degeneration

2006
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity.
    PLoS biology, 2006, Volume: 4, Issue:12

    Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Mice; Mutant Proteins; NAD; Nerve Degeneration; Neurons; Nicotinamide-Nucleotide Adenylyltransferase; Retina; Wallerian Degeneration

2006