Page last updated: 2024-08-17

nad and Tuberculosis

nad has been researched along with Tuberculosis in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199017 (51.52)18.7374
1990's1 (3.03)18.2507
2000's6 (18.18)29.6817
2010's7 (21.21)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Agarwal, A; Chinta, KC; Glasgow, JN; Lumamba, K; Nadeem, S; Naidoo, T; Nargan, K; Pacl, HT; Reddy, VP; Sevalkar, RR; Steyn, AJC1
Ferraris, DM; Garavaglia, S; Gelardi, ELM; Miggiano, R; Rizzi, M1
Crans, DC; Crick, DC; Koehn, JT; Kumar, S; Lott, JS; McNeil, MR; Rooker, SA; Upadhyay, A1
Muronetz, VI; Schmalhausen, EV; Shumkov, MS; Švedas, VK1
Ariyachaokun, K; Beckham, KSH; Botella, L; Boudehen, YM; Cianci, M; Colom, A; de Carvalho, LPS; Freire, DM; Garza-Garcia, A; Genevaux, P; Grabowska, AD; Gutierrez, C; Neyrolles, O; Panikova, T; Parret, AHA; Peixoto, A; Pogenberg, V; Sala, AJ; Schnappinger, D; Schneider, TR; Svergun, DI; Tuukkanen, A; Wilmanns, M1
Deshmukh, S; Harinath, BC; Jena, L; Kumar, S; Waghmare, P1
Penberthy, WT1
Miller, CL1
Chen, B; Jacobs, WR; Vilchèze, C; Weinrick, B; Wong, KW1
Singh, V; Somvanshi, P1
Bernadou, J; Bernardes-Génisson, V; Constant, P; Delaine, T; Meunier, B; Quémard, A1
PATIALA, J1
KERPPOLA, W; PATIALA, J1
ARTMAN, M; BEKIERKUNST, A1
ARTMAN, M; BEKIERKUNST, A; WINDMAN, I1
ARTMAN, M; BEKIERKUNST, A; SILMAN, N1
ALEXANDER, N; ARTMAN, M; BEKIERKUNST, A1
GOPINATHAN, KP; SIRSI, M; VAIDYANATHAN, CS1
Bernadou, J; Bernardes-Génisson, V; Broussy, S; Gornitzka, H; Meunier, B1
Basso, LA; de Sousa, EH; de Souza, ON; Moreira, IS; Oliveira, JS; Santos, DS1
Besra, GS; Dover, LG; Gulten, G; Jacobs, WR; Langley, R; Sacchettini, JC; Wang, F1
Barry, CE; Boshoff, HI; Camacho, LR; Dowd, CS; Ehrt, S; Park, TH; Pethe, K; Schnappinger, D; Tahlan, K; Williams, KJ; Xu, X; Yun, CS1
Basso, LA; Blanchard, JS; Jacobs, WR; Musser, JM; Zheng, R1
Martin, SP; Mathur, PP; Shah, NS2
Shah, NS2
Bekierkunst, A1
Ando, F; Toida, I; Yamamoto, S3
Bekierkunst, A; Windman, I2

Reviews

2 review(s) available for nad and Tuberculosis

ArticleYear
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer.
    Biochemical Society transactions, 2020, 04-29, Volume: 48, Issue:2

    Topics: Aldehyde Oxidoreductases; Animals; Antimalarials; Antitubercular Agents; Communicable Diseases; Drug Design; Drug Discovery; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Inhibins; Isoenzymes; Malaria; NAD; Neoplasms; Oxidoreductases; Tuberculosis

2020
Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex.
    Current pharmaceutical design, 2006, Volume: 12, Issue:19

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Humans; Isoniazid; Kinetics; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis

2006

Other Studies

31 other study(ies) available for nad and Tuberculosis

ArticleYear
NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis.
    Nature communications, 2023, 09-06, Volume: 14, Issue:1

    Topics: Animals; Glycolysis; Homeostasis; Lactate Dehydrogenase 5; Mice; Myeloid Cells; NAD; Niacinamide; Tuberculosis

2023
Mycobacterial MenJ: An Oxidoreductase Involved in Menaquinone Biosynthesis.
    ACS chemical biology, 2018, 09-21, Volume: 13, Issue:9

    Topics: Bacterial Proteins; Biosynthetic Pathways; Flavin-Adenine Dinucleotide; Humans; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Oxidoreductases; Recombinant Proteins; Tuberculosis; Ubiquinone; Vitamin K 2

2018
Expression of glyceraldehyde-3-phosphate dehydrogenase from M. tuberculosis in E. coli. Purification and characteristics of the untagged recombinant enzyme.
    Protein expression and purification, 2019, Volume: 157

    Topics: Amino Acid Sequence; Cloning, Molecular; Escherichia coli; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Mycobacterium tuberculosis; NAD; Protein Folding; Recombinant Proteins; Sequence Alignment; Tuberculosis

2019
An NAD
    Molecular cell, 2019, 03-21, Volume: 73, Issue:6

    Topics: Animals; Antibiotics, Antitubercular; Antitoxins; Bacterial Load; Bacterial Proteins; Bacterial Toxins; Cells, Cultured; Disease Models, Animal; Female; Host-Pathogen Interactions; Humans; Kinetics; Macrophages; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Microbial Viability; Models, Molecular; Mycobacterium smegmatis; Mycobacterium tuberculosis; NAD; Phosphorylases; Protein Conformation; Toxin-Antitoxin Systems; Tuberculosis

2019
Study of mechanism of interaction of truncated isoniazid-nicotinamide adenine dinucleotide adduct against multiple enzymes of Mycobacterium tuberculosis by a computational approach.
    International journal of mycobacteriology, 2015, Volume: 4, Issue:4

    Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Molecular Docking Simulation; Mycobacterium tuberculosis; NAD; Tuberculosis

2015
Nicotinamide adenine dinucleotide biology and disease.
    Current pharmaceutical design, 2009, Volume: 15, Issue:1

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Multiple Sclerosis; NAD; Neoplasms; Schizophrenia; Tuberculosis

2009
The evolution of schizophrenia: a model for selection by infection, with a focus on NAD.
    Current pharmaceutical design, 2009, Volume: 15, Issue:1

    Topics: Biological Evolution; Humans; Kynurenine; Models, Biological; NAD; Schizophrenia; Selection, Genetic; Tuberculosis

2009
NAD+ auxotrophy is bacteriocidal for the tubercle bacilli.
    Molecular microbiology, 2010, Volume: 76, Issue:2

    Topics: Animals; Biosynthetic Pathways; Colony Count, Microbial; Disease Models, Animal; Mice; Microbial Viability; Models, Biological; Mycobacterium bovis; Mycobacterium tuberculosis; NAD; Niacinamide; Tuberculosis; Virulence

2010
Toward the virtual screening of potential drugs in the homology modeled NAD+ dependent DNA ligase from Mycobacterium tuberculosis.
    Protein and peptide letters, 2010, Volume: 17, Issue:2

    Topics: Amino Acid Sequence; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Computational Biology; Databases, Protein; DNA Ligases; Drug Design; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mycobacterium tuberculosis; NAD; Phylogeny; Protein Binding; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Tuberculosis

2010
Development of isoniazid-NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis

2010
The amount of pyridine nucleotides (coenzymes I and II) in blood in experimental tuberculosis before and during isoniazid treatment.
    American review of tuberculosis, 1954, Volume: 70, Issue:3

    Topics: Coenzymes; Isomerism; Isoniazid; NAD; Niacin; Nicotinic Acids; Nucleotides; Tuberculosis

1954
Pyridinenucleotides (coenzyme I and II) of blood in normal subjects and in various diseases, especially tuberculosis.
    Annales medicinae experimentalis et biologiae Fenniae, 1954, Volume: 32, Issue:7

    Topics: Blood; Humans; NAD; Nucleotides; Thoracic Cavity; Tuberculosis; Tuberculosis, Pulmonary

1954
Tissue metabolism in infection. DPNase activity, DPN levels, and DPN-linked dehydrogenases in tissues from normal and tuberculous mice.
    The American review of respiratory disease, 1962, Volume: 86

    Topics: Animals; L-Lactate Dehydrogenase; Liver; Lung; Metabolism; Mice; NAD; NAD+ Nucleosidase; Nucleotidases; Oxidoreductases; Splenectomy; Tuberculosis

1962
PARTICULATE, SOLUBLE AND PLASMA NICOTINAMIDE-ADENINE DINUCLEOTIDE GLYCOHYDROLASE IN NORMAL AND TUBERCULOUS GUINEA-PIGS.
    Biochimica et biophysica acta, 1964, Feb-10, Volume: 82

    Topics: Animals; Blood Chemical Analysis; Clinical Enzyme Tests; Glycoside Hydrolases; Guinea Pigs; Kidney; Liver; Lung; NAD; Plasma; Research; Spleen; Transferases; Tuberculosis

1964
TISSUE METABOLISM IN INFECTION. SOLUBLE NICOTINAMIDE-ADENINE DINUCLEOTIDASE IN ORGANS FROM TUBERCULOUS MICE.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Adenine; Animals; Liver; Lung; Metabolism; Mice; Mycobacterium tuberculosis; NAD; Niacin; Niacinamide; Nucleotidases; Research; Tuberculosis

1964
NICOTINAMIDE ADENINE DINUCLEOTIDASE ACTIVITY IN CELLS OF TUBERCULOUS ANIMALS.
    Science (New York, N.Y.), 1964, Jul-17, Volume: 145, Issue:3629

    Topics: Adenine; Animals; Guinea Pigs; Leukocytes; Lymphoid Tissue; Metabolism; Mice; Monocytes; NAD; Niacinamide; Nucleotidases; Research; Tuberculosis

1964
NICOTINAMIDE-ADENINE DINUCLEOTIDE-GLYCOHYDROLASE ACTIVITY IN EXPERIMENTAL TUBERCULOSIS.
    The Biochemical journal, 1965, Volume: 94

    Topics: Animals; Biochemical Phenomena; Biochemistry; Chloromercuribenzoates; Enzyme Inhibitors; Ethylmaleimide; Isoniazid; Liver; Lung; Metabolism; Mice; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Research; Tuberculosis

1965
Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct.
    Organic & biomolecular chemistry, 2005, Feb-21, Volume: 3, Issue:4

    Topics: Crystallography, X-Ray; Humans; Isoniazid; Molecular Conformation; Molecular Structure; NAD; Niacin; Pyridines; Tuberculosis

2005
Mechanism of thioamide drug action against tuberculosis and leprosy.
    The Journal of experimental medicine, 2007, Jan-22, Volume: 204, Issue:1

    Topics: Antitubercular Agents; Bacterial Proteins; Crystallography, X-Ray; Drug Design; Drug Resistance, Multiple, Bacterial; Ethionamide; Humans; In Vitro Techniques; Leprostatic Agents; Leprosy; Models, Molecular; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium leprae; Mycobacterium tuberculosis; NAD; Oxidoreductases; Prothionamide; Tuberculosis; Tuberculosis, Multidrug-Resistant

2007
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
    The Journal of biological chemistry, 2008, Jul-11, Volume: 283, Issue:28

    Topics: Animals; Genome, Bacterial; Homeostasis; Lung; Macrophages; Mice; Mutation; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Pentosyltransferases; Transcription, Genetic; Tuberculosis

2008
Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:3

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Microbial; Humans; Isoniazid; Mutagenesis; Mutation; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis

1998
Actions of isoniazid on NADH dehydrogenase activity of kidney of tuberculous guinea pigs.
    Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:2

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Isoniazid; Kidney; NAD; Oxidoreductases; Tuberculosis

1966
Nicotinamide adenine dinucleotidase activity in experimental tuberculosis.
    Biochimica et biophysica acta, 1966, Mar-28, Volume: 117, Issue:1

    Topics: Animals; Brain; Guinea Pigs; In Vitro Techniques; Kidney; Liver; N-Glycosyl Hydrolases; NAD; Spleen; Tuberculosis

1966
Subcellular distribution of nicotinamide adenine dinucleotidase in the spleen of tuberculous guinea pigs and tuberculous guinea pigs treated with isoniazid.
    The American review of respiratory disease, 1967, Volume: 96, Issue:1

    Topics: Animals; Cell Nucleus; Centrifugation; Enzymes; Guinea Pigs; Isoniazid; Male; Microsomes; Mitochondria; NAD; Nucleotidases; Spleen; Tuberculosis

1967
Effect of isoniazid on preservation of nicotinamide dinucleotide in animal cells.
    Archives of biochemistry and biophysics, 1967, Mar-20, Volume: 118, Issue:3

    Topics: Alcohol Oxidoreductases; Animals; Carcinoma, Ehrlich Tumor; Isoniazid; Liver; Lung; Mice; NAD; Nucleotidases; Spleen; Triaziquone; Tuberculosis

1967
[Biochemical study on the host response to tuberculous infection. 3. Significance of live tubercle bacilli to the metabolic changes of host].
    Kekkaku : [Tuberculosis], 1967, Volume: 42, Issue:5

    Topics: Animals; Cortisone; Female; Glycoside Hydrolases; Injections, Intravenous; Liver; Lung; Mice; Mycobacterium tuberculosis; NAD; Tuberculosis

1967
[Biochemical study on the host response to tuberculous infection. 2. NAD-ase of tuberculous mouse].
    Kekkaku : [Tuberculosis], 1967, Volume: 42, Issue:4

    Topics: Acid Phosphatase; Animals; Glycoside Hydrolases; Guinea Pigs; Mice; NAD; Succinate Dehydrogenase; Tuberculosis

1967
Biochemical study on the host response to tuberculous infection. IV. Influences of isoniazid, streptomycin, nicotinamide, and cortisone.
    The American review of respiratory disease, 1968, Volume: 98, Issue:3

    Topics: Animals; Cortisone; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Niacinamide; Streptomycin; Tuberculosis

1968
Nicotinamide adenine dinucleotide levels and nadase activity in polymorphonuclear leukocytes, alveolar macrophages, and erythrocytes of tuberculous guinea pigs.
    The American review of respiratory disease, 1969, Volume: 100, Issue:2

    Topics: Animals; Centrifugation; Erythrocytes; Guinea Pigs; Leukocytes; Macrophages; N-Glycosyl Hydrolases; NAD; Pulmonary Alveoli; Tuberculosis

1969
Oxidized and reduced forms of nicotinamide nucleotides in livers of tuberculous mice.
    The American review of respiratory disease, 1967, Volume: 96, Issue:2

    Topics: Animals; Liver; Mice; NAD; NAD+ Nucleosidase; Oxidation-Reduction; Tuberculosis

1967
Isocitric dehydrogenase and nicotinamide adenine dinucleotidase in experimental tuberculosis: influence of isoniazid on metabolic damage.
    The American review of respiratory disease, 1967, Volume: 95, Issue:2

    Topics: Animals; Guinea Pigs; Isocitrate Dehydrogenase; Isoniazid; Kidney; Male; NAD; NADP; Nucleotidases; Tuberculosis

1967