nad has been researched along with Obesity in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (11.65) | 18.7374 |
| 1990's | 2 (1.94) | 18.2507 |
| 2000's | 3 (2.91) | 29.6817 |
| 2010's | 45 (43.69) | 24.3611 |
| 2020's | 41 (39.81) | 2.80 |
| Authors | Studies |
|---|---|
| Akiu, M; Asano, D; Honda, T; Iida, K; Nakamura, T; Pinkerton, AB; Sakurai, K; Sogawa, Y; Tanaka, J; Terayama, K; Tsuji, T; Yokoyama, M | 1 |
| Chen, W; Cong, L; Jiang, Y; Li, H; Sun, Y; Wang, H; Wang, Y; Xu, J; Yang, Q; Zhu, J | 1 |
| Blanco-Vaca, F; Canyelles, M; Escolà-Gil, JC; Julve, J; Mauricio, D; Rotllan, N | 1 |
| Kalso, E; Lötsch, J; Mäntyselkä, P; Miettinen, T; Nieminen, AI | 1 |
| Chen, Y; Deng, H; Liu, X; Luo, C; Wang, X; Yang, C | 1 |
| Bittel, AJ; Bittel, DC; Cade, WT; Cho, K; Klein, S; Mittendorfer, B; Patterson, BW; Patti, GJ; Reeds, DN; Sinacore, DR; Smith, GI; Stein, RI; Yoshino, J; Yoshino, M | 1 |
| Aflatounian, A; Bertoldo, MJ; Cochran, BJ; Edwards, MC; Gilchrist, RB; Ledger, WL; Paris, VR; Richani, D; Walters, KA; Wu, LE | 1 |
| Barrow, M; Chambers, L; Seidler, K | 1 |
| Hikosaka, K; Iqbal, T; Karim, M; Matsumoto, M; Nakagawa, T; Nawaz, A; Yaku, K | 1 |
| Ban, J; Chen, S; Chen, X; Jia, Z; Li, Z; Niu, S; Pan, X; Ren, Q; Yue, L; Zhen, R; Zhu, R | 1 |
| Bolaños-Jiménez, F; Croyal, M; García Santillán, JA; Gourdel, M; Mezo-González, CE; Reyes-Castro, LA | 1 |
| Apte, RS; Bhargava, A; Bhasin, S; Cheng, M; Ghattas-Puylara, C; Latham, N; Lavu, S; Lawney, B; Lin, AP; Livingston, D; Memish-Beleva, Y; Merugumala, S; Orkaby, AR; Ozimek, NE; Pencina, KM; Reid, KF; Sinclair, DA; Storer, T; Swain, PM; Valderrabano, R; Wilson, L; Wipper, B | 1 |
| Tian, D; Wang, H; Wang, M; Xi, P; Zhang, Y; Zhu, W | 1 |
| Musi, N | 1 |
| Kosugi, S; Nagahisa, T; Yamaguchi, S | 1 |
| Barrès, R; Basse, AL; Dalbram, E; Dall, M; Frost, M; Færgeman, NJ; Gerhart-Hines, Z; Havelund, JF; Ingerslev, LR; Karavaeva, I; Ma, T; Nielsen, KN; Nielsen, TS; Peics, J; Treebak, JT; Zierath, JR | 1 |
| Craighead, DH; Freeberg, KA; Martens, CR; Seals, DR; Udovich, CC | 1 |
| Ding, Q; Guan, XH; Jiang, MX; Li, Q; Wang, LF; Wen, K; Xiao, YF; Zhang, F; Zhao, JL; Zhao, QH | 1 |
| Guo, L; Li, BY; Liu, Y; Peng, WQ; Tang, QQ | 1 |
| Adlakha, N; Mishra, V | 1 |
| Baldeiras, I; Cavallaro, CH; Cunha-Oliveira, T; Diniz, MS; Ford, S; Grilo, LF; Martins, JD; Nathanielsz, PW; Oliveira, PJ; Pereira, SP; Tocantins, C | 1 |
| Bae, HR; Han, Y; Kim, S; Kwon, EY; Shin, SK; Yoo, JH; Young, HA | 1 |
| Meza, CA | 1 |
| Craighead, DH; Freeberg, KA; McCarty, NP | 1 |
| Fascia, BJ; Glasgow, AC; Karabinus, JA | 1 |
| Agerholm, M; Altıntaş, A; Barrès, R; Chubanava, S; Dollerup, OL; Høyer, KF; Jessen, N; Larsen, S; Lavery, GG; Møller, AB; Prats, C; Ringgaard, S; Stødkilde-Jørgensen, H; Søndergård, SD; Treebak, JT | 1 |
| Ferreira, MJ | 1 |
| Lee, AY; Lin, F; Ngo, K; Nguyen, HP; Shin, G; Sul, HS; Tabuchi, C; Viscarra, JA; Wang, Y; Yi, D | 1 |
| Dolai, S; Gaisano, HY; Kang, F; Miao, Y; Takahashi, T | 1 |
| Kim, MS; Roh, E | 1 |
| Aarts, SABM; Auwerx, J; Connell, NJ; de Wit, VHW; Elfrink, HL; Havekes, B; Hoeks, J; Houtkooper, RH; Lindeboom, L; Lutgens, E; Mevenkamp, J; Moonen, MPB; Phielix, E; Remie, CME; Roumans, KHM; Schomakers, BV; Schrauwen, P; Schrauwen-Hinderling, VB; van de Weijer, T; Zapata-Pérez, R | 1 |
| Boriek, AM; Pardo, PS | 1 |
| Aonuma, K; Feng, D; Ieda, M; Li, S; Murakoshi, N; Okabe, Y; Qin, R; Tajiri, K; Xu, D; Yonebayashi, S; Yuan, Z | 1 |
| Miller, R; Richards, GA; Wentzel, AR | 1 |
| Chaudhary, R; Heilbronn, L; Hutchison, AT; Liu, B; Page, AJ; Regmi, P; Vincent, AD | 1 |
| Fernández, AF; Fraga, MF; Roberti, A | 1 |
| Franczyk, MP; Imai, SI; Kayser, BD; Klein, S; Mills, KF; Patterson, BW; Patti, GJ; Pietka, T; Sindelar, M; Yoshino, J; Yoshino, M | 1 |
| Abel, ED; Karwi, QG; Lopaschuk, GD; Tian, R; Wende, AR | 1 |
| Cao, X; Han, X; Huang, WY; Jia, W; Li, J; Peng, S; Peng, Y; Wang, L; Xu, Y; Ye, J; Ye, X; Zhang, S; Zhang, X; Zhou, Y | 1 |
| Akar, FG; Young, LH | 1 |
| Butterworth, S; Davis, ET; Jones, SW; Philp, AM | 1 |
| Audrito, V; Brandimarte, L; Deaglio, S; Messana, VG | 1 |
| Lu, J; Ma, DF; Qin, SP; Sun, CH; Wang, AM; Wang, X; Zhang, ZF; Zheng, GH; Zheng, YL; Zhuang, J | 1 |
| Avola, R; Barbagallo, I; Cinà, D; Currenti, W; D'Orazio, N; Galvano, F; Godos, J; Lembo, V; Li Volti, G; Morisco, F; Salomone, F | 1 |
| Huang, HC; Kao, MC; Kuo, HP; Kuo, YH; Lai, YT; Lee, HK; Lee, YJ; Liu, JY; Ou, CC; Tseng, HH; Tu, YC; Yang, BF; Yang, YC; Yeh, WC | 1 |
| Birngruber, R; Casper, M; Evans, CL; Evers, M; Manstein, D; Osseiran, S; Salma, N | 1 |
| Hee Lee, C; Hong, D; Hoon Son, G; Kim, MS; Kim, S; Myoung Kang, G; Roh, E; Young Gil, S | 1 |
| Chowdhury, S; Haque, S; Mehedi, I; Nahid, NA; Poddar, SK; Sifat, AE | 1 |
| Bock, KW | 1 |
| Boulangé, CL; Chou, CJ; Claus, SP; Collino, S; Dumas, ME; Holmes, E; Kochhar, S; Martin, FP; Montoliu, I; Nicholson, JK; Rezzi, S | 1 |
| Choi, SE; Fu, T; Kang, Y; Kemper, B; Kemper, JK; Kim, DH; Lee, KW; Li, X; Seok, S; Yu, E | 1 |
| Bakker, BM; Bleeker, A; den Besten, G; Gerding, A; Groen, BK; Houten, SM; Krab, K; Reijngoud, DJ; Simons, SM; Touw, CM; van Eunen, K | 1 |
| Cowin, GJ; Eriksson, NA; Fitzsimmons, RL; Goode, JM; Muscat, GE; Pearen, MA; Thomas, GP; Tuong, ZK; Wang, SC | 1 |
| Choi, SE; Kemper, JK | 1 |
| Choi, JM; Kim, L; Lee, WY; Oh, KW; Park, CY; Park, SE; Park, SW; Rhee, EJ; Yang, SJ | 1 |
| Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L | 1 |
| Bailey, SM; Udoh, US; Young, ME | 1 |
| Fan, SH; Hu, B; Lu, J; Shan, Q; Wu, DM; Zhang, ZF; Zheng, YL | 1 |
| Borradaile, NM; Chan, P; Hughes-Large, JM; Pang, DK; Robson, DL; Toma, J | 1 |
| Becherer, JD; Boros, EE; Cadilla, R; Carpenter, T; Cowan, D; Deaton, DN; Guo, Y; Haffner, CD; Harrington, W; Henke, BR; Jeune, MR; Kaldor, I; Milliken, N; Petrov, KG; Preugschat, F; Schulte, C; Shearer, BG; Shearer, T; Smalley, TL; Stewart, EL; Stuart, JD; Ulrich, JC | 1 |
| Cho, JH; Chou, JY; Jun, HS; Kim, GY; Lee, YM; Mansfield, BC; Pan, CJ; Springer, DA | 1 |
| Buzadzic, B; Daiber, A; Jankovic, A; Korac, A; Korac, B; Otasevic, V; Stancic, A | 1 |
| de Giorgis, T; Garten, A; Gorski, T; Kiess, W; Penke, M; Schuster, S | 1 |
| Becherer, JD; Boros, EE; Carpenter, TY; Cowan, DJ; Deaton, DN; Haffner, CD; Jeune, MR; Kaldor, IW; Poole, JC; Preugschat, F; Rheault, TR; Schulte, CA; Shearer, BG; Shearer, TW; Shewchuk, LM; Smalley, TL; Stewart, EL; Stuart, JD; Ulrich, JC | 1 |
| Hakkarainen, A; Heinonen, S; Jukarainen, S; Kaprio, J; Lundbom, J; Lundbom, N; Muniandy, M; Pietiläinen, KH; Pirinen, E; Rämö, JT; Rappou, E; Rinnankoski-Tuikka, R; Rissanen, A; Tummers, M | 1 |
| Hakkarainen, A; Heinonen, S; Jukarainen, S; Kaye, S; Lundbom, J; Lundbom, N; Pietiläinen, KH; Pirinen, E; Rappou, E; Rinnankoski-Tuikka, R; Rissanen, A; Saunavaara, V; Virtanen, KA | 1 |
| Verdin, E | 1 |
| Kawano, K; Saiga, M; Yamada, K; Yamanaka, Y; Yamato, M | 1 |
| Fukushima, A; Lopaschuk, GD | 1 |
| Drew, JE; Farquharson, AJ; Horgan, GW; Williams, LM | 1 |
| Franklin, DA; Kim, TH; Liu, S; Zhang, Y | 1 |
| Cai, W; Feng, J; Gao, G; Gong, B; Li, L; Li, Q; Ou, Z; Qi, W; Yang, X; Yang, Z; Zhao, A; Zhao, Z; Zhong, J; Zhou, T | 1 |
| Yamaguchi, S; Yoshino, J | 1 |
| Dubouchaud, H; Favier, R; Goglia, F; Guigas, B; Leverve, XM; Moreno, M; Taleux, N; Weitzel, JM | 1 |
| Choi, HS; Chung, J; Han, J; Hwang, JH; Jang, C; Jo, EJ; Jo, YS; Kho, YL; Kim, DW; Kim, JM; Kim, YK; Kwak, TH; Kweon, GR; Kyung, T; Lee, I; Lee, SH; Park, JH; Park, MK; Shong, M; Yoo, SK | 1 |
| Azuma, K; Goodpaster, BH; Kelley, DE; Menshikova, EV; Ritov, VB; Ruderman, NB; Toledo, FG; Wood, R | 1 |
| Gerner, RR; Moschen, AR; Tilg, H | 1 |
| Chau, MD; Gao, J; Gromada, J; Wu, Z; Yang, Q | 1 |
| Gayol, Mdel C; Hisano, N; Labourdette, VB; Posadas, M; Vázquez, SM | 1 |
| Choudhury, M; Friedman, JE; Jonscher, KR | 1 |
| McBurney, MW; Wu, D; Wu, J; Yan, M; Yu, Q; Zhai, Q; Zhang, F; Zhang, Y; Zhou, B | 1 |
| Duarte, FV; Gomes, AP; Hubbard, BP; Jones, JG; Nunes, P; Palmeira, CM; Rolo, AP; Sinclair, DA; Teodoro, JS; Varela, AT | 1 |
| Danzer, C; Gasperikova, D; Krek, W; Krishnan, J; Kumpf, S; Mirtschink, P; Pedrazzini, T; Simka, T; Ukropcova, B; Ukropec, J; Walter, KM | 1 |
| Ahmad, F; Baar, K; Beaven, MA; Brown, AL; Burgin, AB; Chung, JH; Ke, H; Kim, MK; Luo, H; Manganiello, V; Park, SJ; Philp, A; Rehmann, H; Taussig, R; Williams, T | 1 |
| Andreux, PA; Auwerx, J; Cantó, C; Cen, Y; Cettour-Rose, P; Fernandez-Marcos, PJ; Gademann, K; Houtkooper, RH; Oosterveer, MH; Pirinen, E; Rinsch, C; Sauve, AA; Schoonjans, K; Yamamoto, H; Youn, DY | 1 |
| Corkey, BE; Shirihai, O | 1 |
| Fukuda, D; Hirata, Y; Kurobe, H; Maeda, N; Masuzaki, H; Sakaue, H; Sata, M; Sato, H; Shimabukuro, M; Shimomura, I; Shiota, A; Soeki, T; Uematsu, E | 1 |
| Barbosa, MT; Capellini, V; Chini, EN; Escande, C; Gomes, AP; Nin, V; O'Neil, L; Price, NL; Sinclair, DA; White, TA | 1 |
| Chung, JJ; Kim, JB; Park, J | 1 |
| McMinn, MR | 1 |
| Brady, PS; Hoppel, CL | 1 |
| Chowers, I; Levy, J; Siegel, RA; Weidenfeld, J | 1 |
| Assimacopoulos-Jeannet, F; Girardier, L; Jeanrenaud, B; Rohner-Jeanrenaud, F; Seydoux, J | 1 |
| Barletta, A; Iossa, S; Lionetti, L; Liverini, G; Mollica, MP | 1 |
| Ayre, KJ; Calvert, GD; Fraser, AM; Helge, JW; Jenkins, AB; Kriketos, AD; Storlien, LH | 1 |
| Gawler, DJ; Houslay, MD; Milligan, G; Wilson, A | 1 |
| Agren, A; Berne, C; Brolin, SE | 1 |
| Ellerman, JE; Fertel, R; Kotler-Brajtburg, J; krzanowski, J; Matschinsky, FM | 1 |
| Christensen, NC; Hörder, M; Simonsen, EE; Toft, H | 1 |
| Kågedal, B; Laurell, S; Rooth, G | 1 |
| Berne, C; Gunnarsson, R; Hellerström, C | 1 |
| Hellman, B | 1 |
| Berne, C; Brolin, SE; Isacsson, U | 1 |
22 review(s) available for nad and Obesity
| Article | Year |
|---|---|
NAD+-Increasing Strategies to Improve Cardiometabolic Health?
Topics: Cardiovascular Diseases; Humans; Muscle, Skeletal; NAD; Obesity | 2021 |
Nutritional entrainment of circadian rhythms under alignment and misalignment: A mechanistic review.
Topics: Circadian Rhythm; Humans; Insulin; NAD; Obesity; Sirtuins | 2022 |
Interactions between Intestinal Homeostasis and NAD
Topics: AMP-Activated Protein Kinases; Biology; Cytokines; Glucagon-Like Peptide 1; Glucose; Glucose Intolerance; Homeostasis; Humans; Incretins; NAD; Nicotinamide Phosphoribosyltransferase; Obesity | 2023 |
Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions.
Topics: Aged; Aging; Dietary Supplements; Humans; NAD; Nicotinamide Mononucleotide; Obesity | 2023 |
Susceptibility Factors and Cellular Mechanisms Underlying Alcoholic Pancreatitis.
Topics: Acetaldehyde; Autophagy; Calcium; Disease Susceptibility; Endoplasmic Reticulum Stress; Ethanol; Exocytosis; Genetic Predisposition to Disease; Humans; Hyperlipidemias; Infections; NAD; Obesity; Pancreatitis, Alcoholic; Protective Factors; Reactive Oxygen Species; Risk Factors; Severity of Illness Index; Smoking; SNARE Proteins | 2020 |
Hypothalamic NAD
Topics: Aged; Aging; Chronobiology Disorders; Circadian Rhythm; Energy Metabolism; Humans; Hypothalamus; NAD; Obesity; Sirtuins | 2020 |
SIRT1 Regulation in Ageing and Obesity.
Topics: Aging; Animals; Diabetes Mellitus, Type 2; DNA Damage; Exercise; Gene Expression Regulation; Humans; Hypoxia; Inflammation; Insulin Resistance; Metabolic Syndrome; Mice; NAD; Obesity; Oxidative Stress; Protein Domains; Protein Processing, Post-Translational; Risk; Sirtuin 1; Stress, Mechanical | 2020 |
Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation.
Topics: Adipose Tissue; Animals; Epigenesis, Genetic; Humans; Insulin Resistance; Liver; NAD; Neoplasms; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; S-Adenosylmethionine | 2021 |
Cardiac Energy Metabolism in Heart Failure.
Topics: Adenosine Triphosphate; Amino Acids, Branched-Chain; Comorbidity; Diabetes Mellitus, Type 2; Energy Metabolism; Epigenesis, Genetic; Fatty Acids; Glucose; Glycolysis; Heart Failure; Humans; Insulin Resistance; Ketone Bodies; Mitochondria; Myocardium; NAD; Obesity; Oxidation-Reduction | 2021 |
The Extracellular NADome Modulates Immune Responses.
Topics: Adenosine Triphosphate; Animals; Humans; Immunomodulation; Inflammatory Bowel Diseases; NAD; Neoplasms; Obesity; Sepsis | 2021 |
Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule.
Topics: Alzheimer Disease; Animals; Cardiovascular Diseases; Diabetes Mellitus; Humans; NAD; Nicotinamide Mononucleotide; Obesity | 2019 |
Aryl hydrocarbon receptor (AHR) functions in NAD
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Humans; Myelopoiesis; NAD; Obesity; Receptors, Aryl Hydrocarbon; Signal Transduction | 2019 |
Regulation of SIRT1 by microRNAs.
Topics: Animals; Gene Expression Regulation; Humans; MicroRNAs; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Sirtuin 1; Sirtuins; Up-Regulation | 2013 |
Circadian regulation of metabolism.
Topics: Acetylglucosamine; Adenosine Diphosphate Ribose; Alcohol Drinking; Amino Acids; AMP-Activated Protein Kinases; Animals; Carbohydrate Metabolism; Circadian Clocks; Circadian Rhythm; Diabetes Mellitus; Energy Metabolism; Heme; Homeostasis; Humans; Light; Lipid Metabolism; Mitochondria; NAD; Obesity; Proteins; Sleep; Sleep Disorders, Circadian Rhythm; Suprachiasmatic Nucleus; Wakefulness | 2014 |
Redox implications in adipose tissue (dys)function--A new look at old acquaintances.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Hydrogen Peroxide; Insulin Resistance; Metabolic Syndrome; Mitochondria; NAD; NADPH Oxidases; Obesity; Oxidation-Reduction | 2015 |
Physiological and pathophysiological roles of NAMPT and NAD metabolism.
Topics: Animals; Cytokines; Diabetes Mellitus, Type 2; Humans; NAD; Nicotinamide Phosphoribosyltransferase; Obesity | 2015 |
NAD⁺ in aging, metabolism, and neurodegeneration.
Topics: Aging; Biosynthetic Pathways; Diabetes Mellitus, Type 2; DNA Damage; Fatty Liver; Humans; Mitochondria; NAD; Neurodegenerative Diseases; Obesity; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Sirtuins | 2015 |
Acetylation control of cardiac fatty acid β-oxidation and energy metabolism in obesity, diabetes, and heart failure.
Topics: Acetyl Coenzyme A; Acetylation; Animals; Diabetes Mellitus; Energy Metabolism; Fatty Acids; Heart Failure; Humans; Myocardium; NAD; Obesity; Oxidation-Reduction | 2016 |
Adipose tissue NAD
Topics: Adipose Tissue; Animals; Humans; Insulin Resistance; Models, Biological; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; PPAR gamma; Protein Processing, Post-Translational; Sirtuin 1; Translational Research, Biomedical | 2017 |
Pre-B cell colony enhancing factor/NAMPT/visfatin in inflammation and obesity-related disorders.
Topics: Animals; Fatty Liver; Humans; Inflammation; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Tumor Necrosis Factor-alpha | 2010 |
New evaluations of redox regulating system in adipose tissue of obesity.
Topics: Adipose Tissue; Homeostasis; Humans; Inflammation; Models, Biological; NAD; NADP; Obesity; Oxidation-Reduction; Oxidative Stress | 2007 |
Quantitative histochemistry of glucose metabolism in the islets of Langerhans.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Citrates; Glucose; Glucosephosphates; Glutamates; Glycogen; Hexokinase; Hexosediphosphates; Hexosephosphates; Hyperglycemia; Islets of Langerhans; Lactates; Methods; Mice; NAD; NADP; Obesity; Organophosphorus Compounds; Pyruvates; Spectrometry, Fluorescence; Uridine Diphosphate Sugars | 1971 |
6 trial(s) available for nad and Obesity
| Article | Year |
|---|---|
Worksite-based intensive lifestyle therapy has profound cardiometabolic benefits in people with obesity and type 2 diabetes.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Life Style; Male; NAD; Obesity; Sirtuins; Triglycerides; Workplace | 2022 |
Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older Adults: A Physiologic Study.
Topics: Aged; Body Weight; Cholesterol; Humans; Insulin Resistance; Middle Aged; NAD; Nicotinamide Mononucleotide; Obesity; Overweight | 2023 |
Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin-resistant men.
Topics: Humans; Insulin Resistance; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Obesity; Pyridinium Compounds | 2020 |
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans.
Topics: Acetylcarnitine; Aged; Body Composition; Dietary Supplements; Female; Humans; Male; Middle Aged; Muscle, Skeletal; NAD; Niacinamide; Obesity; Overweight; Pyridinium Compounds | 2020 |
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.
Topics: Aged; Body Composition; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin; Insulin Resistance; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Obesity; Overweight; Postmenopause; Prediabetic State; RNA-Seq; Signal Transduction | 2021 |
Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.
Topics: Adipose Tissue, White; Adult; Counseling; Cytokines; Diet, Reducing; Down-Regulation; Female; Humans; Male; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Poly(ADP-ribose) Polymerases; Signal Transduction; Sirtuin 1; Sirtuins; Subcutaneous Fat; Up-Regulation; Weight Loss | 2016 |
75 other study(ies) available for nad and Obesity
| Article | Year |
|---|---|
Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator.
Topics: Animals; Anti-Obesity Agents; Body Weight; Diabetes Mellitus, Type 2; Humans; Male; Mice, Obese; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Small Molecule Libraries; Structure-Activity Relationship; Urea | 2021 |
NAD
Topics: Gene Regulatory Networks; Humans; Mitochondrial Diseases; NAD; Obesity; Oocytes; Sirtuin 3 | 2021 |
Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes.
Topics: Adenosine Monophosphate; Biomarkers; Chronic Pain; Cysteine; Female; Humans; Machine Learning; Metabolome; Metabolomics; Methionine; NAD; Obesity; Phenotype; Sleep Wake Disorders | 2022 |
Nicotinamide reprograms adipose cellular metabolism and increases mitochondrial biogenesis to ameliorate obesity.
Topics: Adipose Tissue; Animals; Glucose; Mice; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Obesity; Organelle Biogenesis; Proteomics | 2022 |
Declining muscle NAD
Topics: Animals; Dihydrotestosterone; Female; Humans; Hyperandrogenism; Insulin Resistance; Lipids; Metabolic Syndrome; Mice; Muscle, Skeletal; NAD; Nicotinamide Mononucleotide; Obesity; Polycystic Ovary Syndrome | 2022 |
Loss of hepatic Nmnat1 has no impact on diet-induced fatty liver disease.
Topics: Animals; Diet; Liver; Mice; Mice, Inbred C57BL; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Non-alcoholic Fatty Liver Disease; Obesity | 2022 |
Metabolomics Provides Insights into Renoprotective Effects of Semaglutide in Obese Mice.
Topics: Adenosine; Animals; Insulin Resistance; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NAD; Obesity | 2022 |
Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism.
Topics: Animals; Brain; Female; Kynurenic Acid; Kynurenine; Memory Disorders; NAD; Obesity; Rats; Tryptophan | 2023 |
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet.
Topics: Animals; Body Composition; Diet, High-Fat; Metabolic Diseases; Mice; NAD; Nicotinamide Mononucleotide; Obesity; Sirtuins | 2023 |
NAD-elevating Interventions for Cardiometabolic Disease.
Topics: Aged; Aging; Cardiovascular Diseases; Humans; Middle Aged; NAD; Obesity; Overweight | 2023 |
NAMPT-dependent NAD
Topics: Adipose Tissue, Brown; Animals; Circadian Rhythm; Cytokines; NAD; Nicotinamide Phosphoribosyltransferase; Obesity | 2023 |
CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD
Topics: Adipose Tissue, Brown; Animals; Diet, High-Fat; Energy Metabolism; Mice; Mice, Inbred C57BL; Muscle, Skeletal; NAD; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Sirtuin 1 | 2023 |
HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway.
Topics: Adipocytes, Brown; Adipose Tissue, Brown; Adipose Tissue, White; Animals; DNA Damage; Mice; Mice, Inbred C57BL; NAD; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Sirtuin 1; Thermogenesis | 2023 |
Numerical simulation of calcium dynamics dependent ATP degradation, IP
Topics: Adenosine Triphosphate; Calcium; Calcium Signaling; Hepatocytes; Humans; NAD; Obesity | 2023 |
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress.
Topics: Animals; Antioxidants; Catalase; Female; Glutathione; Humans; Liver; Liver Diseases; NAD; Obesity; Oxidative Stress; Pregnancy; Sheep; Superoxide Dismutase | 2023 |
D-Allulose Ameliorates Dysregulated Macrophage Function and Mitochondrial NADH Homeostasis, Mitigating Obesity-Induced Insulin Resistance.
Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Homeostasis; Humans; Inflammation; Insulin Resistance; Insulins; Macrophages; Mice; Mice, Inbred C57BL; Mitochondria; NAD; Obesity | 2023 |
Home exercise reduces cardiometabolic disease risk.
Topics: Cardiovascular Diseases; Exercise; Humans; NAD; Obesity | 2019 |
Overcoming exercise barriers: home-based HIT for reducing cardiovascular disease risk in obese individuals.
Topics: Cardiovascular Diseases; Exercise; Humans; NAD; Obesity | 2020 |
Clapping jumping jacks to improve endothelial function in obese adults: if you're happy and you NO it, clap your hands.
Topics: Cardiovascular Diseases; Hand; Humans; NAD; Obesity | 2020 |
Advances for high-intensity interval training prescription in obesity.
Topics: Cardiovascular Diseases; High-Intensity Interval Training; Humans; NAD; Obesity | 2020 |
Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Apoptosis Regulatory Proteins; Diet; Energy Metabolism; Glucose; Glycolysis; HEK293 Cells; Humans; Insulin Resistance; Lipid Droplets; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Membranes; Mitochondrial Proteins; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Obesity; Oxidation-Reduction; Oxygen Consumption; Thermogenesis; Uncoupling Protein 1 | 2020 |
Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway.
Topics: Animals; Atrial Fibrillation; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Diet, High-Fat; Heart Atria; Male; Mice, Knockout; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Ryanodine Receptor Calcium Release Channel | 2020 |
COVID-19: NAD
Topics: ADAM17 Protein; ADP-ribosyl Cyclase 1; Age Factors; Aged; Aging; COVID-19; Diabetes Mellitus, Type 2; Disease Progression; Disease Susceptibility; Humans; Inflammation; Membrane Glycoproteins; NAD; Obesity; Oxidative Stress; Protein Binding; Sirtuin 1; Virus Replication; Zinc | 2020 |
Early or delayed time-restricted feeding prevents metabolic impact of obesity in mice.
Topics: Animals; Circadian Rhythm; Diet, High-Fat; Fasting; Fatty Liver; Glucose; Glucose Tolerance Test; Liver; Male; Mice, Inbred C57BL; NAD; Obesity; Random Allocation | 2021 |
ADP Induces Blood Glucose Through Direct and Indirect Mechanisms in Promotion of Hepatic Gluconeogenesis by Elevation of NADH.
Topics: Adenosine Diphosphate; Animals; Diet; Glucagon; Gluconeogenesis; Glucose; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Obesity; Signal Transduction; Thinness | 2021 |
NAD Repletion Therapy: A Silver Bullet for HFpEF?
Topics: Heart Failure; Humans; NAD; Obesity; Stroke Volume | 2021 |
eNAMPT Is Localised to Areas of Cartilage Damage in Patients with Hip Osteoarthritis and Promotes Cartilage Catabolism and Inflammation.
Topics: Aged; Aged, 80 and over; Cartilage, Articular; Chemokines; Chondrocytes; Cytokines; Hip Joint; Humans; Matrix Metalloproteinase 13; Matrix Metalloproteinases; Middle Aged; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Organ Culture Techniques; Osteoarthritis, Hip; Proteoglycans | 2021 |
The Inhibitory Effects of Purple Sweet Potato Color on Hepatic Inflammation Is Associated with Restoration of NAD⁺ Levels and Attenuation of NLRP3 Inflammasome Activation in High-Fat-Diet-Treated Mice.
Topics: Animals; Anthocyanins; Anti-Inflammatory Agents; Diet, High-Fat; Endoplasmic Reticulum Stress; Gene Expression Regulation; Hepatitis, Animal; Inflammasomes; Ipomoea batatas; Liver; Mice; NAD; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nod Signaling Adaptor Proteins; Obesity; Oxidative Stress; Pigments, Biological; Plant Extracts; Protein Transport | 2017 |
Silibinin Restores NAD⁺ Levels and Induces the SIRT1/AMPK Pathway in Non-Alcoholic Fatty Liver.
Topics: Adenylate Kinase; Animals; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Humans; Mice; Mice, Inbred C57BL; NAD; Non-alcoholic Fatty Liver Disease; Obesity; Silybin; Silymarin; Sirtuin 1 | 2017 |
Proteomic profiling of Ganoderma tsugae ethanol extract-induced adipogenesis displaying browning features.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Adipogenesis; Animals; Blotting, Western; Diet; Drugs, Chinese Herbal; Electrophoresis, Gel, Two-Dimensional; Ethanol; Fungal Proteins; Ganoderma; Male; Mice; NAD; Obesity; Organelle Biogenesis; Oxidation-Reduction; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Uncoupling Protein 1 | 2018 |
Enhanced quantification of metabolic activity for individual adipocytes by label-free FLIM.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Drug Evaluation, Preclinical; Energy Metabolism; Mice; Microscopy, Fluorescence; Mitochondria; NAD; Obesity; Optical Imaging | 2018 |
Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice.
Topics: Animals; Circadian Rhythm; Dietary Supplements; Energy Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NAD; Obesity | 2018 |
Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways.
Topics: Adaptation, Physiological; Animals; Diet, High-Fat; Female; Hemiterpenes; Keto Acids; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mitochondria; NAD; Obesity; Oxidation-Reduction; Succinic Acid; Urine; Weight Gain | 2013 |
Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.
Topics: 3' Untranslated Regions; Animals; Cytokines; Gene Expression Regulation; Gene Silencing; Liver; Male; Mice; Mice, Inbred BALB C; MicroRNAs; NAD; Nicotinamide Phosphoribosyltransferase; Obesity; Protein Binding; RNA, Messenger; Sirtuin 1 | 2013 |
Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.
Topics: Animals; Carnitine; Fatty Acids; Female; Kinetics; Liver; Metabolic Networks and Pathways; Mitochondria; Models, Biological; NAD; Obesity; Oxidation-Reduction; Palmitoyl Coenzyme A; Palmitoylcarnitine; Rats; Rats, Wistar; Reproducibility of Results | 2013 |
Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance.
Topics: Adipose Tissue; Adiposity; Animals; Carbohydrate Metabolism; Diet, High-Fat; DNA-Binding Proteins; Glycogen; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; NAD; Nerve Tissue Proteins; Obesity; Organ Specificity; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Endurance; Receptors, Steroid; Receptors, Thyroid Hormone; Transcription Factors; Transcriptome; Triglycerides | 2013 |
Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; Male; Mitochondrial Turnover; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Inbred OLETF; Signal Transduction; Sirtuin 1; Sirtuins; Transcription Factors | 2014 |
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, Type 2; Diet; Energy Metabolism; Fatty Liver; Gene Knockdown Techniques; Glucose Intolerance; Glucose Transporter Type 4; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; S-Adenosylmethionine; Sirtuin 1; Spermine; Thinness | 2014 |
Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice.
Topics: Animals; Diet, High-Fat; Fatty Liver; Hydroxyethylrutoside; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; NAD; Nuclear Proteins; Obesity; Oxidative Stress; Phosphatidate Phosphatase; Signal Transduction; Sirtuin 1 | 2014 |
Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity.
Topics: Animals; Aorta; Apoptosis; Cattle; Cell Death; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Drug Combinations; Endothelial Cells; Gene Expression Regulation; Humans; Immunohistochemistry; Laminin; Lipids; Metabolic Syndrome; Microcirculation; NAD; Niacin; Nicotinamide Mononucleotide; Obesity; Protein Binding; Proteoglycans; Pyrazoles; Receptors, G-Protein-Coupled; Receptors, Nicotinic; RNA Interference; RNA, Small Interfering; Serum Albumin | 2014 |
Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.
Topics: ADP-ribosyl Cyclase 1; Animals; Cell Line; Dogs; Drug Discovery; Humans; Liver; Mice, Inbred C57BL; Molecular Docking Simulation; Muscles; NAD; Obesity; Quinolones; Thiazoles | 2015 |
Mice expressing reduced levels of hepatic glucose-6-phosphatase-α activity do not develop age-related insulin resistance or obesity.
Topics: AMP-Activated Protein Kinases; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Dependovirus; Disease Models, Animal; Energy Metabolism; Gene Expression; Genetic Therapy; Genetic Vectors; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; Insulin Resistance; Liver; Mice; Mice, Knockout; NAD; Nuclear Proteins; Obesity; Signal Transduction; Sirtuin 1; Transcription Factors | 2015 |
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
Topics: ADP-ribosyl Cyclase 1; Amides; Aminoquinolines; Animals; Biological Availability; Crystallography, X-Ray; Humans; Hydrolysis; Liver; Membranes, Artificial; Mice, Inbred C57BL; Models, Molecular; Muscle, Skeletal; NAD; Obesity; Permeability; Protein Conformation; Quinolines; Stereoisomerism; Structure-Activity Relationship | 2015 |
Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Body Composition; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Down-Regulation; Female; Finland; Glucose Tolerance Test; Humans; Insulin Resistance; Life Style; Male; NAD; Obesity; Sirtuins; Twins, Monozygotic | 2016 |
TEMPOL increases NAD(+) and improves redox imbalance in obese mice.
Topics: Animals; Antioxidants; Ascorbic Acid; Cyclic N-Oxides; Diet, High-Fat; Electron Spin Resonance Spectroscopy; Energy Metabolism; Ethidium; Glutathione; Humans; Mice; Mice, Obese; NAD; Obesity; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spin Labels | 2016 |
Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding.
Topics: Adipose Tissue, White; Adiposity; Animals; Biomarkers; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Glucose Intolerance; Liver; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle, Skeletal; NAD; Nicotinamide N-Methyltransferase; Obesity; Organ Specificity; Principal Component Analysis; Sirtuins; Tryptophan Oxygenase; Weight Gain | 2016 |
Protection against High-Fat-Diet-Induced Obesity in MDM2
Topics: Adipose Tissue; Animals; Cell Differentiation; Cell Line; Diet, High-Fat; Energy Metabolism; Gene Expression Regulation; Glucose Transporter Type 4; Longevity; Mice; NAD; Nicotinamide N-Methyltransferase; Obesity; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-mdm2; Proto-Oncogene Proteins c-myc; Ribosomal Proteins; Sirtuin 1; Survival Rate; Tumor Suppressor Protein p53 | 2017 |
IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity.
Topics: 3T3-L1 Cells; Adenosine Triphosphate; Adipose Tissue; Adipose Tissue, White; Animals; Body Mass Index; Cell Polarity; Cell Respiration; Eating; Humans; Interleukin-17; Lipolysis; Liver; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitochondria; Models, Biological; NAD; Non-alcoholic Fatty Liver Disease; Obesity; Oxygen Consumption; RNA, Messenger; Weight Gain | 2018 |
High expression of thyroid hormone receptors and mitochondrial glycerol-3-phosphate dehydrogenase in the liver is linked to enhanced fatty acid oxidation in Lou/C, a rat strain resistant to obesity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fatty Acids; Gluconeogenesis; Glycerol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Hepatocytes; Male; Mitochondria, Liver; Monocarboxylic Acid Transporters; NAD; Obesity; Oxidation-Reduction; Rats; Rats, Wistar; Receptors, Thyroid Hormone; Species Specificity | 2009 |
Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice.
Topics: Adenylate Kinase; Animals; Disease Models, Animal; Energy Metabolism; Metabolic Syndrome; Mice; Mice, Knockout; NAD; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Naphthoquinones; Obesity; Oxidation-Reduction; Phenotype; Signal Transduction | 2009 |
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adult; Biopsy; Blood Glucose; Cardiolipins; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Electron Transport; Humans; Insulin Resistance; Lipid Metabolism; Middle Aged; Mitochondria; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Obesity; Oxidative Phosphorylation; Quadriceps Muscle; Trichloroacetic Acid | 2010 |
Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway.
Topics: Adipocytes; Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Energy Metabolism; Fibroblast Growth Factors; Genes; Glucose; Homeostasis; Male; Mice; Mice, Obese; Mitochondria; NAD; Obesity; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Random Allocation; Signal Transduction; Sirtuin 1 | 2010 |
Auerbach plexus structure with NADH histochemistry in a line of obese rats: effects of dietary restriction.
Topics: Animals; Diet, Reducing; Histocytochemistry; Intestine, Small; Male; Myenteric Plexus; NAD; Obesity; Rats; Time Factors | 2010 |
Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat.
Topics: Aging; Animals; Caloric Restriction; Fatty Liver; Liver; Mice; Mitochondria; NAD; Obesity; Phenotype; Sirtuin 3 | 2011 |
WldS enhances insulin transcription and secretion via a SIRT1-dependent pathway and improves glucose homeostasis.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; C-Peptide; Cell Line, Tumor; Diet, High-Fat; Fluorescent Antibody Technique; Glucose; Immunohistochemistry; Immunoprecipitation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; NAD; NADP; Nerve Tissue Proteins; Niacin; Obesity; Real-Time Polymerase Chain Reaction; Signal Transduction; Sirtuin 1 | 2011 |
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.
Topics: AMP-Activated Protein Kinases; Animals; Berberine; Cell Line; Diet, High-Fat; Glucose; Hormones; Hyperglycemia; Insulin Resistance; Male; Mice; Mitochondria; Mitochondria, Muscle; Muscle, Skeletal; Myoblasts; NAD; Obesity; Organelle Biogenesis; Phosphorylation; Rats; Rats, Sprague-Dawley; Sirtuin 1 | 2012 |
Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.
Topics: Acetylation; Adipocytes; Animals; Base Sequence; Cell Differentiation; Cells, Cultured; Diet; Energy Metabolism; Fatty Acids; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mitochondria; Molecular Sequence Data; NAD; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sequence Alignment; Sirtuin 2; Trans-Activators; Transcription Factors | 2012 |
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue, White; Aging; AMP-Activated Protein Kinase Kinases; Animals; Caloric Restriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Diet; Glucose Intolerance; Guanine Nucleotide Exchange Factors; Mice; Models, Molecular; Muscle, Skeletal; NAD; Obesity; Protein Kinases; Resveratrol; Rolipram; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Topics: Acetylation; Adipose Tissue, Brown; Animals; Brain; Diet, High-Fat; Dietary Supplements; Electron Transport Complex I; Energy Metabolism; HEK293 Cells; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal; NAD; Niacinamide; Obesity; Organ Specificity; Oxidation-Reduction; Oxygen Consumption; Protein Processing, Post-Translational; Pyridinium Compounds; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Sirtuin 1; Sirtuin 3; Superoxide Dismutase; Weight Gain | 2012 |
Metabolic master regulators: sharing information among multiple systems.
Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Insulin Resistance; Lactic Acid; Liver; Metabolome; Mitochondria; Models, Biological; Muscles; NAD; NADP; Obesity; Oxidation-Reduction; Pyruvic Acid; Signal Transduction | 2012 |
Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.
Topics: Adipocytes; Administration, Oral; AMP-Activated Protein Kinases; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Fatty Acid Transport Proteins; Glucose Transporter Type 4; Hypertrophy; Insulin; Islets of Langerhans; Male; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; NAD; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; RNA, Messenger; Signal Transduction; Sirtuin 1; Telmisartan; Time Factors; Trans-Activators; Transcription Factors | 2012 |
Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome.
Topics: ADP-ribosyl Cyclase 1; Animals; Apigenin; Cell Line, Tumor; Gene Expression Regulation; Humans; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; NAD; Obesity; Quercetin; Random Allocation; Sirtuin 1 | 2013 |
Mechanisms of energy balance in obesity.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Eating; Energy Intake; Energy Metabolism; Female; Glycerophosphates; Lipoprotein Lipase; Male; NAD; Obesity; Physical Exertion; Rats; Sodium-Potassium-Exchanging ATPase | 1984 |
Peroxisomal palmitoyl-CoA oxidation in the Zucker rat.
Topics: Acyl Coenzyme A; Animals; Catalase; Female; Liver; Male; Microbodies; NAD; Obesity; Organ Size; Organoids; Oxidation-Reduction; Palmitoyl Coenzyme A; Rats; Rats, Zucker; Starvation | 1983 |
In vitro metabolism of cortisol by human abdominal adipose tissue.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Abdomen; Adipose Tissue; Adult; Female; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; NAD; NADP; Obesity; Time Factors | 1982 |
Functional disconnection of brown adipose tissue in hypothalamic obesity in rats.
Topics: Adipose Tissue, Brown; Animals; Caprylates; DNA; Female; Hypothalamus; NAD; NADP; Norepinephrine; Obesity; Oxidation-Reduction; Rats; Sympathetic Nervous System | 1981 |
Hepatic mitochondrial respiration and transport of reducing equivalents in rats fed an energy dense diet.
Topics: Animals; Biological Transport; Diet, Reducing; Energy Intake; Energy Metabolism; Glutamic Acid; Glycerolphosphate Dehydrogenase; Malates; Male; Mitochondria, Liver; NAD; Obesity; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Rats; Rats, Wistar | 1995 |
Interrelationships between muscle fibre type, substrate oxidation and body fat.
Topics: Adult; Blood Glucose; Body Composition; Citrate (si)-Synthase; Cross-Sectional Studies; Exercise; Exercise Test; Humans; Hydrocortisone; Insulin; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; NAD; Obesity; Oxygen Consumption; Pulmonary Gas Exchange; Reference Values; Respiratory Function Tests | 1999 |
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella | 1989 |
Influence of ischemia on the levels of reduced pyridine nucleotides in the pancreatic islets.
Topics: Animals; Hyperglycemia; Ischemia; Islets of Langerhans; Liver; Luciferases; Male; Mice; NAD; NADP; Obesity; Pancreas; Photochemistry; Rats | 1973 |
Serum triglyceride values in healthy adults.
Topics: Adult; Age Factors; Female; Humans; Male; Middle Aged; NAD; Obesity; Oxidation-Reduction; Triglycerides | 1969 |
The effect of variation of lipolysis after nicotinic acid and acetylsalicylate on blood concentrations of 3-hydroxybutyrate and acetoacetate in starving subjects.
Topics: Acetoacetates; Adolescent; Adult; Aspirin; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Hydroxybutyrates; Lipid Metabolism; Male; Middle Aged; NAD; Nicotinic Acids; Obesity; Starvation | 1970 |
Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Female; Glucose; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; NAD; Niacinamide; Nitrosourea Compounds; Obesity; Oxygen Consumption; Streptozocin | 1974 |
Some metabolic aspects of the obese-hyperglycemic syndrome in mice.
Topics: Adipose Tissue; Animals; Atrophy; Female; Glucose Tolerance Test; Glucuronidase; Hyperglycemia; Isocitrate Dehydrogenase; Liver; Male; Mice; Muscles; NAD; NADP; Obesity; Testis | 1967 |
Photokinetic assay of NADH and NADPH in microdissected tissue samples.
Topics: Alcaligenes; Alcohol Oxidoreductases; Animals; Glucosephosphate Dehydrogenase; Glutathione Reductase; Hydroxybutyrate Dehydrogenase; Hyperglycemia; Islets of Langerhans; Kinetics; Liver; Luciferases; Mice; Mice, Inbred Strains; Micromanipulation; NAD; NADP; Obesity; Oscillometry; Oxidation-Reduction; Pancreas; Rhodobacter sphaeroides; Saccharomyces cerevisiae | 1972 |