nad has been researched along with Leigh Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beyrath, J; Iannetti, EF; Koopman, WJH; Smeitink, JAM; Willems, PHGM | 1 |
| Abell, L; Caudal, A; Lee, CF; Nagana Gowda, GA; Tian, R | 1 |
| Aubut, C; Boucher, G; Clish, CB; Cyr, D; Daneault, C; Des Rosiers, C; Laprise, C; Mootha, VK; Morin, C; Rioux, JD; Sharma, R; Strittmatter, L; Tardif, J; Thompson Legault, J; Tremblay-Vaillancourt, V; Vachon, L; Waters, PJ | 1 |
| Arnaud, E; Bahlo, M; Chrast, R; Davey, GM; Heath, WR; Hewitt, CA; Kinkel, SA; Komen, JC; Laskowski, A; Leong, DW; McKenzie, M; Phipson, B; Pitt, JJ; Ryan, MT; Scott, HS; Sickmann, A; Smyth, GK; Thorburn, DR; Voss, AK; Zahedi, RP | 1 |
| Marsac, C; Stansbie, D; Wallace, SJ | 1 |
| Becker, L; De Meirleir, L; Glerum, M; Robinson, BH; Sherwood, G | 1 |
1 review(s) available for nad and Leigh Disease
| Article | Year |
|---|---|
Disorders of the pyruvate dehydrogenase complex.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coenzyme A; Cranial Nerves; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Facial Bones; Feedback; Humans; Lactates; Lactic Acid; Leigh Disease; Molecular Weight; Movement Disorders; NAD; Nervous System Diseases; Phosphoric Monoester Hydrolases; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Spectrophotometry | 1986 |
5 other study(ies) available for nad and Leigh Disease
| Article | Year |
|---|---|
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
Topics: Adenosine Triphosphate; Aspartic Acid; Cell Death; Culture Media; Electron Transport Complex I; Fibroblasts; Galactose; Gene Expression; Glycolysis; Humans; Ketoglutaric Acids; Leigh Disease; Malates; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Oxaloacetic Acid; Primary Cell Culture; Pyruvic Acid; Skin | 2018 |
Targeting NAD
Topics: Animals; Brain; Disease Models, Animal; Electron Transport Complex I; Female; Leigh Disease; Longevity; Male; Mice; Mice, Knockout; Mitochondria; Molecular Targeted Therapy; NAD; Nicotinamide Mononucleotide | 2019 |
A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome
Topics: Adiponectin; Adolescent; Adult; Amines; Biomarkers; Case-Control Studies; Child; Female; Humans; Insulin; Leigh Disease; Lipid Metabolism; Male; Metabolome; Mitochondria; NAD; Neoplasm Proteins | 2015 |
Proteomic and metabolomic analyses of mitochondrial complex I-deficient mouse model generated by spontaneous B2 short interspersed nuclear element (SINE) insertion into NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) gene.
Topics: Animals; Binding Sites; DNA Transposable Elements; Electron Transport Complex I; Humans; Leigh Disease; Metabolomics; Mice; Mice, Mutant Strains; Mice, Transgenic; Mitochondria; Mutation; NAD; NADH Dehydrogenase; Proteomics; RNA Splicing | 2012 |
Clinical presentation of mitochondrial respiratory chain defects in NADH-coenzyme Q reductase and cytochrome oxidase: clues to pathogenesis of Leigh disease.
Topics: Brain Diseases, Metabolic; Child; Child, Preschool; Citric Acid Cycle; Cytochrome-c Oxidase Deficiency; Female; Fibroblasts; Humans; Infant; Infant, Newborn; Lactates; Leigh Disease; Male; Mitochondria; NAD; NAD(P)H Dehydrogenase (Quinone); Pyruvates; Quinone Reductases | 1987 |